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Results for "

DES

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) Androgen Receptor (1) Apoptosis (1) Autophagy (3) Bacterial (2) Bombesin Receptor (1) Bradykinin Receptor (8) Drug Metabolite (1) Estrogen Receptor/ERR (1) Fluorescent Dye (1) GCGR (4) GHSR (2) GnRH Receptor (9) HIV (1) HIV Protease (1) Isotope-Labeled Compounds (2) Oxytocin Receptor (1) Phospholipase (2) PROTAC Linkers (2) Small Interfering RNA (siRNA) (1) Vasopressin Receptor (2)
By Research Areas:	Cancer (6) Cardiovascular Disease (3) Endocrinology (10) Infection (2) Inflammation/Immunology (9) Metabolic Disease (9) Neurological Disease (2)

By Targets:

Adrenergic Receptor (1)

Androgen Receptor (1)

Apoptosis (1)

Autophagy (3)

Bacterial (2)

Bombesin Receptor (1)

Bradykinin Receptor (8)

Drug Metabolite (1)

Estrogen Receptor/ERR (1)

Fluorescent Dye (1)

GCGR (4)

GHSR (2)

GnRH Receptor (9)

HIV (1)

HIV Protease (1)

Isotope-Labeled Compounds (2)

Oxytocin Receptor (1)

Phospholipase (2)

PROTAC Linkers (2)

Small Interfering RNA (siRNA) (1)

Vasopressin Receptor (2)

By Research Areas:

Cancer (6)

Cardiovascular Disease (3)

Endocrinology (10)

Infection (2)

Inflammation/Immunology (9)

Metabolic Disease (9)

Neurological Disease (2)

Inhibitors & Agonists

Fluorescent Dye

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-132795S

Des(1-cyclohexanol) Venlafaxine-d6

Isotope-Labeled Compounds Others

Des(1-cyclohexanol) Venlafaxine-d₆ is the deuterium labeled Des(1-cyclohexanol) Venlafaxine[1].

Des(1-cyclohexanol) Venlafaxine-d6	Isotope-Labeled Compounds	Others
Des(1-cyclohexanol) Venlafaxine-d₆ is the deuterium labeled Des(1-cyclohexanol) Venlafaxine[1].

HY-15899

Des(benzylpyridyl) Atazanavir	HIV Protease HIV Drug Metabolite	Infection
Des(benzylpyridyl) Atazanavir (compound M1) is a N-dealkylation product of Atazanavir (HY-17367) metabolite. Atazanavir is a highly selective HIV-1 protease inhibitor. Des(benzylpyridyl) Atazanavir may contribute to the effectiveness Atazanavir but also to the toxicity and interactions. Des(benzylpyridyl) Atazanavir can be used for further research of Atazanavir effects .

HY-P5713

Des(8-14)brevinin-1PMa	Bacterial	Infection
Des(8-14)brevinin-1PMa is a host-defense peptide that exhibits antimicrobial activity against Staphylococcus aureus and Echerichia coli. Des(8-14)brevinin-1PMa also shows hemolytic activity .

HY-141757S

Des-p-fluorobenzyl mosapride-d5

Isotope-Labeled Compounds Others

Des-p-fluorobenzyl mosapride-d₅ is the deuterium labeled Des-p-fluorobenzyl mosapride[1].

Des-p-fluorobenzyl mosapride-d5	Isotope-Labeled Compounds	Others
Des-p-fluorobenzyl mosapride-d₅ is the deuterium labeled Des-p-fluorobenzyl mosapride[1].

HY-P4440

*(Des-Gly10,Des-Ser4,D-Leu6,Pro-NHEt9)-LHRH*	GnRH Receptor	Others
(Des-Gly10,Des-Ser4,D-Leu6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P1366

des-Gln14-Ghrelin	GHSR	Metabolic Disease
des-Gln14-Ghrelin is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca ²⁺]i in CHO-GHSR62 cells, with an EC₅₀ of 2.4 nM .

HY-RS03703

DES Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
DES Human Pre-designed siRNA Set A contains three designed siRNAs for DES gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

DES Human Pre-designed siRNA Set A DES Human Pre-designed siRNA Set A

HY-P4467

*(Des-Pyr1,Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH* (DES-Pyr1)-Leuprolide	GnRH Receptor	Others
(Des-Pyr1,Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P1366A

des-Gln14-Ghrelin TFA	GHSR	Metabolic Disease
des-Gln14-Ghrelin TFA is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca ²⁺]i in CHO-GHSR62 cells, with an EC₅₀ of 2.4 nM .

HY-P3209

Des-Arg9-[Leu8]-Bradykinin acetate	Bradykinin Receptor	Inflammation/Immunology
Des-Arg9-[Leu8]-Bradykinin acetate is potent bradykinin receptor 1 (B1R) antagonist. Des-Arg9-[Leu8]-Bradykinin acetate can be used for renal fibrosis research .

HY-P3542

Des His1, Glu8 Exendin-4	GCGR	Metabolic Disease
Des His1, Glu8 Exendin-4 is a potent glucagon-like peptide-1 receptor (GLP-1-R) antagonist. Des His1, Glu8 Exendin-4 improves glucose homeostasis by regulating both insulin secretion and glucose production. Des His1, Glu8 Exendin-4 can be used for the research of type 2 diabetic and gastrointestinal .

HY-P4463

*(Des-Pyr1)-LHRH*	GnRH Receptor	Others
(Des-Pyr1)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P0048

*(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH* Surfagon
(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (Surfagon, Mwt 1167.34 Da) is an agonist of gonadotropin-releasing hormone (GnRH). (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH can be used as an internal standard for the LC-MS analysis of leuprorelide acetate. (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH has potential applications in biochemical analysis and fertility .

HY-P3583

*(Des-Gly10,D-Arg6,Pro-NHEt9)-LHRH II (chicken)*	GnRH Receptor	Others
Des-Gly10,D-Arg6,Pro-NHEt9)-LHRH II (chicken) is an active petide. (Des-Gly10,D-Arg6,Pro-NHEt9)-LHRH II (chicken) can be used for the research of various biochemical studies .

HY-P4413

*(Des-Glu5)-ACTH (1-24) (human, bovine, rat)*	Androgen Receptor	Endocrinology
(Des-Glu5)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production .

HY-P4456

*(Des-His6)-ACTH (1-24) (human, bovine, rat)*	Adrenergic Receptor	Endocrinology
(Des-His6)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production .

HY-P4432

*(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)*	GnRH Receptor	Endocrinology
(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon) is a GnRH analog that induces ovulation and/or spawning in farmed fish .

HY-P4445

*(Des-Gly10,D-Leu6,Orn8,Pro-NHEt9)-LHRH*	GnRH Receptor	Others
(Des-Gly10,D-Leu6,Orn8,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4442

*(Des-Gly10,D-His2,D-Trp6,Pro-NHEt9)-LHRH*	GnRH Receptor	Others
(Des-Gly10,D-His2,D-Trp6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4447

*(Des-Gly10,D-Pyr1,D-Leu6,Pro-NHEt9)-LHRH*	GnRH Receptor	Others
(Des-Gly10,D-Pyr1,D-Leu6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4441

*(Des-Gly10,D-His2,D-His(Bzl)6,Pro-NHEt9)-LHRH*	GnRH Receptor	Others
(Des-Gly10,D-His2,D-His(Bzl)6,Pro-NHEt9)-LHRH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P1490

Bradykinin (2-9) DES-Arg1-bradykinin	Bradykinin Receptor	Cardiovascular Disease Endocrinology
Bradykinin (2-9) is an amino-truncated Bradykinin peptide. Bradykinin (2-9) is a metabolite of Bradykinin, cleaved by Aminopeptidase P.

HY-P3608

*[Des-His1,Glu9] Glucagon*	GCGR	Metabolic Disease
[Des-His1,Glu9] Glucagon is a potent glucagon receptor system peptide antagonist. [Des-His1,Glu9] Glucagon enhances the glucose-stimulated release of insulin from pancreatic islet cells. [Des-His1,Glu9] Glucagon can be used to research diabetes .

HY-N11758

5′-Des-O-methylharringtonine

Others Others

5′-Des-O-methylharringtonine is a nature product that could be isolated from Cephalotaxus harringtonia .

*5′-Des-O-methylharringtonine*	Others	Others
5′-Des-O-methylharringtonine is a nature product that could be isolated from Cephalotaxus harringtonia .

HY-P0298

*[Des-Arg9]-Bradykinin*	Bradykinin Receptor	Inflammation/Immunology Endocrinology
[Des-Arg9]-Bradykinin is a Bradykinin (B₁) receptor agonist that displays selectivity for B₁ over B₂ receptors.

HY-P0298A

*[Des-Arg9]-Bradykinin acetate* 1 Publications Verification	Bradykinin Receptor	Inflammation/Immunology Endocrinology
[Des-Arg9]-Bradykinin acetate is a Bradykinin B₁ receptor agonist that displays selectivity for B₁ over B₂ receptors.

HY-103295

*Lys-[Des-Arg9]Bradykinin*	Bradykinin Receptor	Metabolic Disease Inflammation/Immunology
Lys-[Des-Arg9]Bradykinin, a naturally occurring kinin, is a potent and highly selective bradykinin B1 receptor agonist with a K_i of 0.12 nM, 1.7 nM and 0.23 nM for human, mouse and rabbit B1 receptors, respectively. Lys-[Des-Arg9]Bradykinin has low inhibitory activity on B2 receptors .

HY-P1143

*[Des-His1,Glu9]-Glucagon amide*	GCGR	Metabolic Disease
[Des-His1,Glu9]-Glucagon amide is a potent and peptide antagonist of the glucagon receptor, with a pA₂ of 7.2. [Des-His1,Glu9]-Glucagon amide is potentially useful in the study of the pathogenesis of diabetes .

HY-103295A

*Lys-[Des-Arg9]Bradykinin TFA*	Bradykinin Receptor	Metabolic Disease Inflammation/Immunology
Lys-[Des-Arg9]Bradykinin TFA, a naturally occurring kinin, is a potent and highly selective bradykinin B1 receptor agonist with a K_i of 0.12 nM, 1.7 nM and 0.23 nM for human, mouse and rabbit B1 receptors, respectively. Lys-[Des-Arg9]Bradykinin TFA has low inhibitory activity on B2 receptors .

HY-P1143A

*[Des-His1,Glu9]-Glucagon amide TFA*	GCGR	Metabolic Disease
[Des-His1,Glu9]-Glucagon amide TFA is a potent and peptide antagonist of the glucagon receptor, with a pA₂ of 7.2. [Des-His1,Glu9]-Glucagon amide TFA is potentially useful in the study of the pathogenesis of diabetes .

HY-N9542

Dimethyl Citric acid	Others	Others
Dimethylurea/citric acid is a highly efficient deep eutectic solvent (DES). Dimethylurea/citric acid can be used as a catalyst and a green reaction medium for the synthesis of bis(indolyl)methanes, quinolines and aryl-4, 5-diphenyl-1H-imidazoles.

HY-P4676

Lys-(Des-Arg9,Leu8)-Bradykinin

Bradykinin Receptor Endocrinology

Lys-(Des-Arg9,Leu8)-Bradykinin is a bradykinin B1 receptor antagonist .

*Lys-(Des-Arg9,Leu8)-Bradykinin*	Bradykinin Receptor	Endocrinology
Lys-(Des-Arg9,Leu8)-Bradykinin is a bradykinin B1 receptor antagonist .

HY-103291

*Sar-[D-Phe8]-des-Arg9-Bradykinin*	Bradykinin Receptor	Inflammation/Immunology Endocrinology
Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings .

HY-P4541

*(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14)*	Bombesin Receptor	Cancer
(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14) is a bombesin (BBN) antagonist and can be used for the research of cancer .

HY-P4683

*(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin*	Vasopressin Receptor	Cardiovascular Disease
(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin is a potent vasopressin V1 receptor (VP V1R) antagonist. (Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin significantly decreases the mean arterial pressure (MAP) in rats .

HY-P4683A

*(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin acetate*	Vasopressin Receptor	Cardiovascular Disease
(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin is a potent vasopressin V1 receptor (VP V1R) antagonist. (Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin significantly decreases the mean arterial pressure (MAP) in rats .

HY-P4397

*(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin*	Oxytocin Receptor	Endocrinology
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin, an oxytocin receptor antagonist, abolishes oxytocin-enhanced inhibitory postsynaptic currents in CA1 pyramidal neurons .

HY-122402

Umirolimus	Bacterial	Inflammation/Immunology
Umirolimus, a macrocyclic triene lactone Rapamycin derivative, is powerful immunosuppressant and anti-inflammatory agent. Umirolimus has highly lipophilicity and can be used agent-eluting stent (DES) applications .

HY-14598

Diethylstilbestrol 3 Publications Verification Stilbestrol	Estrogen Receptor/ERR Apoptosis Autophagy	Endocrinology Cancer
Diethylstilbestrol (Stilbestrol) is a non-steroidal female hormone that has oral activity and can act on menopausal and postmenopausal disorders. Diethylstilbestrol can induce DNA oxidation and Apoptosis of spermatogonial stem cells. Diethylstilbestrol can induce thymocyte Autophagy Diethylstilbestrol is a 11β-hydroxysteroid dehydrogenase 2 (HSD11B2) inhibitor. .

HY-W040270

Amino-PEG10-amine	PROTAC Linkers	Cancer
Amino-PEG10-amine, a PEG-based PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer .

HY-130411

Amino-PEG11-amine	PROTAC Linkers	Cancer
Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer .

HY-12807

FIPI 4 Publications Verification 5-Fluoro-2-indolyl DESchlorohalopemide	Phospholipase Autophagy	Inflammation/Immunology Cancer
FIPI (5-Fluoro-2-indolyl des-chlorohalopemide), a derivative of Halopemide (HY-119093), is a phospholipase D (PLD) inhibitor with IC₅₀s of approximately 25 nM and 20 nM for PLD1 and PLD2, respectively. FIPI inhibits PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis. FIPI has the potential for autoimmunity and cancer metastasis research .

HY-D1346

610CP	Fluorescent Dye	Others
610CP is a new type of actin labeling dye. It dissolves in organic solvents. In DMSO the 610CP excitation/emission wavelength is between 609 and 634 nm. 610CP is a fluorescent dye that penetrates living cells. Upon cell entry, 610CP binds to Bromo-des-methyl-Jasplakinolide Therefore, 610CP dye can be used to stain actin fluorescence images with low background and high resolution.

HY-12807A

FIPI hydrochloride 5-Fluoro-2-indolyl DESchlorohalopemide hydrochloride	Phospholipase Autophagy	Inflammation/Immunology Cancer
FIPI (5-Fluoro-2-indolyl des-chlorohalopemide) hydrochloride, a derivative of Halopemide (HY-119093), is a phospholipase D (PLD) inhibitor with IC₅₀s of approximately 25 nM and 20 nM for PLD1 and PLD2, respectively. FIPI hydrochloride inhibits PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis. FIPI hydrochloride has the potential for autoimmunity and cancer metastasis research .

Cat. No.	Product Name	Type