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Dapagliflozin

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10450
    Dapagliflozin
    30+ Cited Publications

    BMS-512148

    		 SGLT Metabolic Disease Cancer
    Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin induces HIF1 expression and attenuates renal IR injury .
    <em>Dapagliflozin</em>
  • HY-128723
    Dapagliflozin impurity

    		SGLT Others
    Dapagliflozin impurity is an enantiomer of Dapagliflozin which is a sodium-glucose transporter 2 inhibitor .
    <em>Dapagliflozin</em> impurity
  • HY-10450S
    Dapagliflozin-d5

    BMS-512148-d5
    Dapagliflozin-d5 is a deuterium labeled Dapagliflozin. Dapagliflozin is a competitive SGLT2 inhibitor[1].
    <em>Dapagliflozin</em>-d5
  • HY-10450A
    Dapagliflozin ((2S)-1,2-propanediol, hydrate)
    30+ Cited Publications

    BMS-512148 (2S)-1,2-propanediol, hydrate

    		 SGLT Metabolic Disease Cancer
    Dapagliflozin ((2S)-1,2-propanediol, hydrate) is the S-enantiomer of Dapagliflozin 1,2-propanediol, hydrate. Dapagliflozin ((2S)-1,2-propanediol, hydrate), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin ((2S)-1,2-propanediol, hydrate) induces HIF1 expression and attenuates renal IR injury .
    <em>Dapagliflozin</em> ((2S)-1,2-propanediol, hydrate)
  • HY-400785
    Dapagliflozin impurity A

    		Others Cancer
    Dapagliflozin impurity A (Compound A) is a dapagliflozin peroxide, a genotoxic impurity, can cause damage to human genetic material at very low concentrations, leading to genetic mutations and possibly tumorigenesis .
    <em>Dapagliflozin</em> impurity A
  • HY-122473
    fluoro-Dapagliflozin

    		SGLT Metabolic Disease
    fluoro-Dapagliflozin, a structural analog of Dapagliflozin, is a selective SGLT2 inhibitor with Ki values of 5.3 nM and 330 nM for SGLT2 and SGLT1, respectively. fluoro-Dapagliflozin blocks glucose transport and glucose-coupled currents .
    fluoro-<em>Dapagliflozin</em>
  • HY-137145
    galacto-Dapagliflozin

    		SGLT Others
    Galacto-dapagliflozin is a selective inhibitor for hSGLT2 with Ki of 25 nM .
    galacto-<em>Dapagliflozin</em>

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