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Results for "

Diclofenac+Sodium

" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-15037
    Diclofenac Sodium
    10+ Cited Publications

    GP 45840

    		 COX Apoptosis Inflammation/Immunology Cancer
    Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.