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Results for "

Diclofenac-d4

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

3

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15036S
    Diclofenac-d4

    		Isotope-Labeled Compounds COX Apoptosis Inflammation/Immunology
    Diclofenac-d4 is the deuterium labeled Diclofenac. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].
    <em>Diclofenac-d4</em>
  • HY-15037S1
    Diclofenac-d4 sodium

    		COX Apoptosis Inflammation/Immunology
    Diclofenac-d4 (sodium) is the deuterium labeled Diclofenac sodium. Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].
    <em>Diclofenac-d4</em> sodium
  • HY-15550S
    4'-Hydroxy diclofenac-d4

    		Drug Metabolite Neurological Disease Inflammation/Immunology
    4'-Hydroxy diclofenac-d4 is the deuterium labeled 4'-Hydroxy diclofenac. 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties[1][2].
    <em>4</em>'-Hydroxy <em>diclofenac-d4</em>

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