Search Result
Results for "
Drug Iintermediate
" in MedChemExpress (MCE) Product Catalog:
4604
Inhibitors & Agonists
1933
Biochemical Assay Reagents
94
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-170587
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- HY-168489
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Drug-Linker Conjugates for ADC
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Cancer
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OBI-992 drug-linker is a drug-linker conjugate composed of a TOP I inhibitor Exatecan (HY-13631) and a linker. OBI-992 drug-linker exhibits antitumor property in mouse models and can be used for synthesis of ADC OBI-992 .
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- HY-163487
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AZD8205 Drug-linker
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Drug-Linker Conjugates for ADC
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Cancer
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Puxitatug samrotecan drug-linker (AZD8205 drug-linker) is part of the anti-B7-H4 antibody-conjugated active molecule ADC (drug-linker conjugate for ADC). Puxitatug samrotecan drug-linker contains a degradable ADC linker and a topoisomerase I inhibitor Exatecan (HY-13631) .
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- HY-176455
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Drug-Linker Conjugates for ADC
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Cancer
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ADC-5 drug-linker (Compound linker-payload 5) is a drug-linker conjugate for ADC with potent anti-tumor activity. ADC-5 drug-linker can be used to synthesize NLRP3 agonist 3 (HY-176452) .
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- HY-172554
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Drug-Linker Conjugates for ADC
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Cancer
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XMT-2056 drug-linker is a drug-linker conjugate linker for a HER2-Directed STING Agonist antibody-Drug Conjugate (XMT-2056, Calotatug ginistinag). Calotatug ginistinag (XMT-2056) is an antibody-drug conjugate targeting HER2, with an effective payload connected via a linker (LP, HY-148067) to a STING agonist (STING agonist-20, HY-148068), and has potential immune activation and anticancer activity .
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- HY-168550
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ADC Linker
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Cancer
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STI-8811 drug-linker is a linker for synthesis of ADC molecule STI-8811 .
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- HY-166975
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pSar 100
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Biochemical Assay Reagents
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Others
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Polysarcosine 100 (pSar 100) is a hydrophilic alternative to PEG that has good targeted drug delivery properties and can remain in the bloodstream longer. Polysarcosine 100 can be used in drug delivery research .
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- HY-166972
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pSar 50
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Biochemical Assay Reagents
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Others
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Polysarcosine 50 (pSar 50) is a hydrophilic alternative to PEG that has good targeted drug delivery properties and can remain in the bloodstream longer. Polysarcosine 50 can be used in drug delivery research .
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- HY-166973
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pSar 20
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Biochemical Assay Reagents
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Others
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Polysarcosine 20 (pSar 20) is a hydrophilic alternative to PEG that has good targeted drug delivery properties and can remain in the bloodstream longer. Polysarcosine 20 can be used in drug delivery research .
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- HY-166974
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pSar 150
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Biochemical Assay Reagents
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Others
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Polysarcosine 150 (pSar 150) is a hydrophilic alternative to PEG that has good targeted drug delivery properties and can remain in the bloodstream longer. Polysarcosine 150 can be used in drug delivery research .
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- HY-167451
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Biochemical Assay Reagents
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Others
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PLLA3000-PEG5000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA3000-PEG5000-N3 can be used in drug delivery research .
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- HY-167447
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Biochemical Assay Reagents
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Others
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PLLA4000-PEG5000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA4000-PEG5000-N3 can be used in drug delivery research .
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- HY-167445
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Biochemical Assay Reagents
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Others
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PLLA5000-PEG2000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA5000-PEG2000-N3 can be used in drug delivery research .
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- HY-167449
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Biochemical Assay Reagents
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Others
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PLLA4000-PEG2000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA4000-PEG2000-N3 can be used in drug delivery research .
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- HY-167462
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Biochemical Assay Reagents
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Others
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PLLA1000-PEG1000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA1000-PEG1000-N3 can be used in drug delivery research .
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- HY-167459
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Biochemical Assay Reagents
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Others
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PLLA1000-PEG5000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA1000-PEG5000-N3 can be used in drug delivery research .
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- HY-167453
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Biochemical Assay Reagents
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Others
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PLLA3000-PEG2000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA3000-PEG2000-N3 can be used in drug delivery research .
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- HY-167464
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Biochemical Assay Reagents
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Others
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PLLA10000-PEG3000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA10000-PEG3000-N3 can be used in drug delivery research .
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- HY-167444
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Biochemical Assay Reagents
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Others
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PLLA5000-PEG3000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA5000-PEG3000-N3 can be used in drug delivery research .
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- HY-167463
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Biochemical Assay Reagents
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Others
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PLLA10000-PEG5000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA10000-PEG5000-N3 can be used in drug delivery research .
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- HY-167461
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Biochemical Assay Reagents
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Others
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PLLA1000-PEG2000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA1000-PEG2000-N3 can be used in drug delivery research .
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- HY-167450
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Biochemical Assay Reagents
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Others
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PLLA4000-PEG1000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA4000-PEG1000-N3 can be used in drug delivery research .
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- HY-167458
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Biochemical Assay Reagents
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Others
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PLLA2000-PEG1000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA2000-PEG1000-N3 can be used in drug delivery research .
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- HY-167454
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Biochemical Assay Reagents
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Others
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PLLA3000-PEG1000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA3000-PEG1000-N3 can be used in drug delivery research .
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- HY-167456
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Biochemical Assay Reagents
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Others
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PLLA2000-PEG3000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA2000-PEG3000-N3 can be used in drug delivery research .
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- HY-167443
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Biochemical Assay Reagents
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Others
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PLLA5000-PEG5000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA5000-PEG5000-N3 can be used in drug delivery research .
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- HY-167465
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Biochemical Assay Reagents
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Others
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PLLA10000-PEG2000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA10000-PEG2000-N3 can be used in drug delivery research .
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- HY-167452
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Biochemical Assay Reagents
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Others
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PLLA3000-PEG3000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA3000-PEG3000-N3 can be used in drug delivery research .
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- HY-167457
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Biochemical Assay Reagents
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Others
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PLLA2000-PEG2000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA2000-PEG2000-N3 can be used in drug delivery research .
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- HY-167466
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Biochemical Assay Reagents
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Others
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PLLA10000-PEG1000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA10000-PEG1000-N3 can be used in drug delivery research .
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- HY-167455
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Biochemical Assay Reagents
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Others
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PLLA2000-PEG5000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA2000-PEG5000-N3 can be used in drug delivery research .
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- HY-167460
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Biochemical Assay Reagents
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Others
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PLLA1000-PEG3000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA1000-PEG3000-N3 can be used in drug delivery research .
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- HY-167446
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Biochemical Assay Reagents
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Others
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PLLA5000-PEG1000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA5000-PEG1000-N3 can be used in drug delivery research .
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- HY-167448
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Biochemical Assay Reagents
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Others
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PLLA4000-PEG3000-N3 is a polylactic acid derivative used for encapsulating hydrophobic drugs. PLLA4000-PEG3000-N3 can be used in drug delivery research .
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- HY-144000
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Liposome
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Others
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DSPE-PEG-PDP is a phospholipid PEG conjugate that can be used in drug delivery applications .
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- HY-143211
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Liposome
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Others
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Murapalmitine is the component of liposomes for drug delivery .
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- HY-143691
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Liposome
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Others
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MGlc-DAG, a glycoglycerolipid, can be used for the synthesis of drug delivery compound .
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- HY-W590546
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- HY-166994
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- HY-166883
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- HY-P99719
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BAY 1129980; Anti-C4.4a antibody-Drug conjugates
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Antibody-Drug Conjugates (ADCs)
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Cancer
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Lupartumab Amadotin (BAY 1129980) is an antibody–drug conjugate (ADC) consisting of a fully human C4.4A (LYPD3)-targeting mAb (BAY 1135626) (HY-147281) conjugated to a novel, highly potent derivative of the microtubule-disrupting cytotoxic drug auristatin via a noncleavable alkyl hydrazide linker. Lupartumab Amadotin can be used for the research of non-small cell lung cancer .
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- HY-142979
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Liposome
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Others
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DSPE-PEG 2000 is a PEG polymer containing DSPE and amine end groups. DSPE-PEG 2000 can be used to form micelles as nanoparticles for drug delivery .
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- HY-142986
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Liposome
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Others
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Dlin-MeOH is a lipid product for use in drug delivery systems .
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- HY-145742
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DSPG sodium
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Liposome
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Cardiovascular Disease
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1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) is the component of liposomes for drug delivery .
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- HY-W590537
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- HY-167021
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Biochemical Assay Reagents
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Cancer
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Cholesterol-doxorubicin is a cholesterol conjugate with good storage stability, low hematotoxicity, and controllable drug delivery properties. Cholesterol-doxorubicin can be used in drug delivery research .
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- HY-150240
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Liposome
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Cancer
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DOPE-GA can be used in the preparation of liposomes for research on drug delivery and other applications .
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- HY-144017
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Liposome
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Others
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12:0 EPC chloride is a cationic phospholipid. 12:0 EPC chloride can be used for drug delivery .
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- HY-W441001
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Biochemical Assay Reagents
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Others
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DSPE-Fluorescein is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-Fluoresceincan be used in drug delivery research .
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- HY-153186
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Liposome
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Others
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LNP Lipid-3 is an ionizable lipid that can be used to synthesize lipid nanoparticles. LNP Lipid-3 can be applied in the research of drug delivery .
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- HY-145782
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- HY-166849
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Biochemical Assay Reagents
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Others
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B22&" is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. "&B22&"can be used in drug delivery research ."
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- HY-W440987
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Biochemical Assay Reagents
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Others
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DOPE-mPEG (MW 1000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations to achieve better therapeutic effects. DOPE-mPEG (MW 1000) can be used in drug delivery research .
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- HY-W800741
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Biochemical Assay Reagents
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Others
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Undecyl 8-bromooctanoate is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations to achieve better therapeutic effects. Undecyl 8-bromooctanoate can be used in drug delivery research .
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- HY-W440989
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Biochemical Assay Reagents
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Others
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DOPE-mPEG (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-mPEG (MW 5000)can be used in drug delivery research .
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- HY-166606
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Biochemical Assay Reagents
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Others
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DSPE-polysarcosine66 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-polysarcosine66can be used in drug delivery research .
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- HY-142984
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Liposome
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Others
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Decanoic acid, 2-hexyl-, 6-oxohexyl ester-1 is a lipid product can be used for drug delivery .
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- HY-142987
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- HY-W591448
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Azide (MW 1000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Azide (MW 1000)can be used in drug delivery research .
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- HY-166846
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Biochemical Assay Reagents
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Others
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DOPE-PEG-FITC (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-FITC (MW 2000)can be used in drug delivery research .
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- HY-166648
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Biochemical Assay Reagents
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Others
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DSPE-PEG-Maleimide (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-PEG-Maleimide (MW 2000)can be used in drug delivery research .
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- HY-W440828
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Biochemical Assay Reagents
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Others
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DOPE-PEG-COOH (MW 3400) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-COOH (MW 3400)can be used in drug delivery research .
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- HY-W440997
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Mal (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Mal (MW 5000)can be used in drug delivery research .
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- HY-W591450
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Azide (MW 3400) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Azide (MW 3400)can be used in drug delivery research .
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- HY-W440993
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Amine (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Amine (MW 5000)can be used in drug delivery research .
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- HY-W440996
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Mal (MW 3400) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Mal (MW 3400)can be used in drug delivery research .
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- HY-166644
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Biochemical Assay Reagents
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Others
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DPPE-PEG-amine (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DPPE-PEG-amine (MW 2000)can be used in drug delivery research .
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- HY-W591451
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Azide (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Azide (MW 5000)can be used in drug delivery research .
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- HY-W440992
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Amine (MW 3400) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Amine (MW 3400)can be used in drug delivery research .
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- HY-W440826
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Biochemical Assay Reagents
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Others
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DOPE-PEG-COOH (MW 1000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-COOH (MW 1000)can be used in drug delivery research .
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- HY-W440829
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Biochemical Assay Reagents
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Others
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DOPE-PEG-COOH (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-COOH (MW 5000)can be used in drug delivery research .
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- HY-166680
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Biochemical Assay Reagents
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Others
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DOPE-PEG-FITC (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-FITC (MW 5000)can be used in drug delivery research .
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- HY-W440994
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Mal (MW 1000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Mal (MW 1000)can be used in drug delivery research .
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- HY-166651
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Biochemical Assay Reagents
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Others
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DSPE-Hyd-PEG-Mal (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-Hyd-PEG-Mal (MW 2000)can be used in drug delivery research .
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- HY-166857
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Biochemical Assay Reagents
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Others
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DMPE-PEG-amine (TFA) (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DMPE-PEG-amine (TFA) (MW 2000)can be used in drug delivery research .
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- HY-166654
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Biochemical Assay Reagents
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Others
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DSPE-Amide-PEG-Rhodamine (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-Amide-PEG-Rhodamine (MW 2000)can be used in drug delivery research .
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- HY-W590667
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Biochemical Assay Reagents
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Others
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C2 Ceramide-1-phosphate is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. C2 Ceramide-1-phosphatecan be used in drug delivery research .
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- HY-166833
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Rhodamine B (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Rhodamine B (MW 5000)can be used in drug delivery research .
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- HY-P10128
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- HY-142985
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Liposome
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Metabolic Disease
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Oleyl Mesylate is a derivative of Oleyl Alcohol. Oleyl Alcohol has been incorporated into various formulations for drug delivery .
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- HY-166852
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Cy5 (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Cy5 (MW 2000)can be used in drug delivery research .
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- HY-W440821
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- HY-166848
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Cy5.5 (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Cy5.5 (MW 2000)can be used in drug delivery research .
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- HY-166850
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Biochemical Assay Reagents
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Others
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DOPE-PEG-Cy5.5 (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Cy5.5 (MW 5000)can be used in drug delivery research .
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- HY-153852
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Liposome
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Others
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1LNP Lipid-7 (Compound 7013) is a lipid. LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) and for drug delivery .
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- HY-144010
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DOPE-PEG2000; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium
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Liposome
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Others
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18:1 PEG2000 PE (18:1 PEG-PE) is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:1 PEG2000 PE can be used for drug delivery .
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- HY-W440922
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Biochemical Assay Reagents
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Others
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m-PEG-DSPE (sodium) (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DSPE (sodium) (MW 1000) can be used in drug delivery research .
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- HY-167022
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Biochemical Assay Reagents
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Others
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DSPE-PEG-azide (MW 600) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-azide (MW 600) can be used in drug delivery research .
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- HY-167036
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Biochemical Assay Reagents
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Others
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DMG-PEG-Mal (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DMG-PEG-Mal (MW 2000) can be used in drug delivery research .
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-
- HY-W440925
-
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Biochemical Assay Reagents
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Others
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|
m-PEG-DSPE (sodium) (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DSPE (sodium) (MW 5000) can be used in drug delivery research .
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-
- HY-W440825
-
|
|
Biochemical Assay Reagents
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Others
|
|
DSPE-PEG-COOH (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-COOH (MW 1000) can be used in drug delivery research .
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-
- HY-166979
-
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|
Biochemical Assay Reagents
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Others
|
|
Stearic acid-mPEG (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Stearic acid-mPEG (MW 2000) can be used in drug delivery research .
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-
- HY-W440932
-
|
|
Biochemical Assay Reagents
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Others
|
|
Stearic acid-mPEG (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Stearic acid-mPEG (MW 5000) can be used in drug delivery research .
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-
- HY-W440930
-
|
|
Biochemical Assay Reagents
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Others
|
|
Stearic acid-mPEG (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Stearic acid-mPEG (MW 1000) can be used in drug delivery research .
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-
- HY-W440894
-
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Biochemical Assay Reagents
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Others
|
|
DSPE-PEG-DBCO (sodium) (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-DBCO (sodium) (MW 5000) can be used in drug delivery research .
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-
- HY-W440942
-
|
|
Biochemical Assay Reagents
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Others
|
|
Pentacosadiynoic acid-mPEG (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Pentacosadiynoic acid-mPEG (MW 2000) can be used in drug delivery research .
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-
- HY-166980
-
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|
Biochemical Assay Reagents
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Others
|
|
m-PEG-DPPE (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DPPE (MW 2000) can be used in drug delivery research .
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-
- HY-167031
-
|
|
Biochemical Assay Reagents
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Others
|
|
DOPE-PEG-DBCO (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DOPE-PEG-DBCO (MW 5000) can be used in drug delivery research .
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-
- HY-166981
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-TCO (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-TCO (MW 2000) can be used in drug delivery research .
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-
- HY-166807
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Palmitate-PEG-Mal (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Palmitate-PEG-Mal (MW 1000) can be used in drug delivery research .
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-
- HY-166968
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-COOH (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-COOH (MW 5000) can be used in drug delivery research .
|
-
- HY-167028
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-alkyne (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-alkyne (MW 2000) can be used in drug delivery research .
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-
- HY-W440943
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Pentacosadiynoic acid-mPEG (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Pentacosadiynoic acid-mPEG (MW 5000) can be used in drug delivery research .
|
-
- HY-W440881
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-DBCO (sodium) (MW 3400) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-DBCO (sodium) (MW 3400) can be used in drug delivery research .
|
-
- HY-166983
-
|
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-DMG (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DMG (MW 5000) can be used in drug delivery research .
|
-
- HY-166982
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-PA (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-PA (MW 2000) can be used in drug delivery research .
|
-
- HY-W440941
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Pentacosadiynoic acid-mPEG (MW 1000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Pentacosadiynoic acid-mPEG (MW 1000) can be used in drug delivery research .
|
-
- HY-W440830
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-COOH (MW 3400) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-COOH (MW 3400) can be used in drug delivery research .
|
-
- HY-W440924
-
|
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-DSPE (sodium) (MW 3000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. m-PEG-DSPE (sodium) (MW 3000) can be used in drug delivery research .
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-
- HY-166992
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1,2-Dioleoyl-sn-glycero-3-PA (ammonium) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. 1,2-Dioleoyl-sn-glycero-3-PA (ammonium)can be used in drug delivery research .
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-
- HY-144013
-
|
DSPE-mPEG2000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium
|
Liposome
|
Others
|
|
18:0 mPEG2000 PE (DSPE-mPEG2000) ammonium is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:0 mPEG2000 PE ammonium can be used for drug delivery .
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-
- HY-166874
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-endo-BCN (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-endo-BCN (MW 2000) can be used in drug delivery research .
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-
- HY-166871
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-endo-BCN (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-endo-BCN (MW 5000) can be used in drug delivery research .
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-
- HY-167024
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol valerate is a cholesterol ester with good biocompatibility, bioavailability and bioactivity. Cholesterol valerate can be used in drug delivery research .
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-
- HY-167025
-
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|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol laurate is a cholesterol ester with good biocompatibility, bioavailability and bioactivity. Cholesterol laurate can be used in drug delivery research .
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-
- HY-148033
-
|
N,N,N-Trimethylchitosan
|
Drug Derivative
|
Others
|
|
Trimethyl chitosan (N,N,N-Trimethylchitosan) is a multifunctional polymer and a derivative of Chitosan (HY-B2144A). Trimethyl chitosan targets the absorption enhancing proteins of tight junctions of intestinal and mucosal epithelial cells, induces tight junction protein rearrangement, and increases intercellular permeability. Trimethyl chitosan can stimulate the activity of promoting transmembrane transport of hydrophilic drugs (such as peptides and proteins) and can be used for drug delivery and synthesis of nanoparticles .
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-
- HY-167000
-
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m-PEG-VS (MW 10000)
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-Vinylsulfone (MW 10000) (m-PEG-VS (MW 10000)) is a PEG derivative that modulates the release of drugs from microparticle systems for parenteral administration. m-PEG-Vinylsulfone (MW 10000) can be used in drug delivery studies .
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-
- HY-166995
-
|
Bis-VS-PEG (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
|
Bis-Vinylsulfone-PEG (MW 5000) (Bis-VS-PEG (MW 5000)) is a PEG derivative that modulates the release of drugs from microparticle systems for parenteral administration. Bis-Vinylsulfone-PEG (MW 5000) can be used in drug delivery studies .
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-
- HY-166998
-
|
m-PEG-VS (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-Vinylsulfone (MW 5000) (m-PEG-VS (MW 5000)) is a PEG derivative that modulates the release of drugs from microparticle systems for parenteral administration. m-PEG-Vinylsulfone (MW 5000) can be used in drug delivery studies .
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-
- HY-166999
-
|
m-PEG-VS (MW 20000)
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-Vinylsulfone (MW 20000) (m-PEG-VS (MW 20000)) is a PEG derivative that modulates the release of drugs from microparticle systems for parenteral administration. m-PEG-Vinylsulfone (MW 20000) can be used in drug delivery studies .
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-
- HY-167016
-
|
|
Liposome
|
Others
|
|
Cholesterol-undecanoate-glucose conjugate is a cholesterol conjugate used in the synthesis of intranasal liposomal vaccines. Cholesterol-undecanoate-glucose conjugate can be used in drug delivery studies .
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-
- HY-144005B
-
|
C16 PEG Ceramide (MW 5000)
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
C16 PEG5000 Ceramide (C16 PEG Ceramide (MW 5000)) is a PEG lipid for the preparation of liposomes and can be used in drug delivery studies .
|
-
- HY-144005A
-
|
C16 PEG Ceramide (MW 750)
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
C16 PEG750 Ceramide (C16 PEG Ceramide (MW 750)) is a PEG lipid for the preparation of liposomes and can be used in drug delivery studies .
|
-
- HY-166993
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cy5-PEG-methyltetrazine (MW 5000) is a PEG derivative that modulates the release of drugs from microparticle systems for parenteral administration. Cy5-PEG-methyltetrazine (MW 5000) can be used in drug delivery studies .
|
-
- HY-150118
-
|
|
Liposome
|
Others
|
|
Lipid 8 is an ionizable amino lipid that can be used to synthesize lipid nanoparticles (LNPs). Lipid 8 is applicable to research in drug delivery .
|
-
- HY-143693
-
|
|
Liposome
|
Others
|
|
DGDG, a chloroplast lipid, is a bilayer-forming lipid. DGDG is important for photosynthesis, and can be used for drug delivery .
|
-
- HY-141892A
-
|
DSPE PEG(2000) Carboxylic Acid sodium
|
Liposome
|
Others
|
|
DSPE-PEG Carboxylic acid (sodium), MW 2000 is a PEG-lipid that can be used in the preparation of drug delivery nanoparticles .
|
-
- HY-166996
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Bis(N-2-ethoxyethyl 2-hexyldecanoate)amine is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Bis(N-2-ethoxyethyl 2-hexyldecanoate)amine can be used in drug delivery research .
|
-
- HY-112197
-
|
|
PKG
|
Cardiovascular Disease
|
|
PKG agent G1 targets C42 of PKG Iα. PKG agent G1 can couple to vasodilation and blood pressure lowering by a C42 PKG Iα-independent mechanism.
|
-
- HY-167115
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA-azide (MW 20000) is a polylactic acid derivative that can self-assemble in water. PLLA-azide (MW 20000) can be used in drug delivery research .
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-
- HY-167071
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA-azide (MW 5000) is a polylactic acid derivative that can self-assemble in water. PLLA-azide (MW 5000) can be used in drug delivery research .
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-
- HY-167117
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA-azide (MW 10000) is a polylactic acid derivative that can self-assemble in water. PLLA-azide (MW 10000) can be used in drug delivery research .
|
-
- HY-156829A
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) is a matrix materia, with lactic acid (LA)：glycolic acid (GA) = 15:1, that acts as anti-cancer drug delivery. PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) can improve a drug's bioavailability, efficacy, water solubility, drug encapsulation efficiency, sustained drug release, and to minimize undesirable toxicity .
|
-
- HY-156829
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 1:1) is a matrix materia, with lactic acid (LA)：glycolic acid (GA) = 1:1, that acts as anti-cancer drug delivery. PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 1:1) can improve a drug's bioavailability, efficacy, water solubility, drug encapsulation efficiency, sustained drug release, and to minimize undesirable toxicity .
|
-
- HY-W440722
-
|
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
Cholesterol-PEG-Thiol (MW 1000) is a PEGylated lipid that forms micelles in water and can be used to prepare liposomes or nanoparticles as drug delivery systems. The thiol moiety reacts with maleimide to form a stable thioether bond .
|
-
- HY-W590547
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(6-(4-Hydroxybutylamino)hexyl)carbamic undecyl is a lipid with a terminal hydroxyl group, which is used to construct or modify lipid nanoparticles (LNP). (6-(4-Hydroxybutylamino)hexyl)carbamic undecyl can be used in drug delivery research .
|
-
- HY-W440835
-
|
DSPE-PEG(2000)-DBCO
|
Liposome
|
Others
|
|
DSPE-PEG-DBCO, MW 2000 is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery . DSPE-PEG-DBCO, MW 2000 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-167064
-
|
DSPE-Polysarcosine50
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-pSar50 (DSPE-Polysarcosine50) is a pSar-lipid derivative. DSPE-pSar50 is a hydrophilic alternative to PEG and can be used in drug delivery research .
|
-
- HY-167068
-
|
Azide-Polysarcosine150
|
Biochemical Assay Reagents
|
Others
|
|
Azide-pSar150 (Azide-Polysarcosine150) is a pSar-lipid derivative. Azide-pSar150 is a hydrophilic alternative to PEG and can be used in drug delivery research .
|
-
- HY-167067
-
|
DSPE-Polysarcosine100
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-pSar100 (DSPE-Polysarcosine100) is a pSar-lipid derivative. DSPE-pSar100 is a hydrophilic alternative to PEG and can be used in drug delivery research .
|
-
- HY-167066
-
|
DSPE-Polysarcosine150
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-pSar150 (DSPE-Polysarcosine150) is a pSar-lipid derivative. DSPE-pSar150 is a hydrophilic alternative to PEG and can be used in drug delivery research .
|
-
- HY-167065
-
|
DSPE-Polysarcosine20
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-pSar20 (DSPE-Polysarcosine20) is a pSar-lipid derivative. DSPE-pSar20 is a hydrophilic alternative to PEG and can be used in drug delivery research .
|
-
- HY-167069
-
|
Azide-Polysarcosine100
|
Biochemical Assay Reagents
|
Others
|
|
Azide-pSar100 (Azide-Polysarcosine100) is a pSar-lipid derivative. Azide-pSar100 is a hydrophilic alternative to PEG and can be used in drug delivery research .
|
-
- HY-167063
-
|
Azide-Polysarcosine20
|
Biochemical Assay Reagents
|
Others
|
|
Azide-pSar20 (Azide-Polysarcosine20) is a pSar-lipid derivative. Azide-pSar20 is a hydrophilic alternative to PEG and can be used in drug delivery research .
|
-
- HY-147018
-
|
|
Liposome
|
Others
|
|
1-Octylnonyl 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl](2-hydroxyethyl)amino]octanoate is a PEG lipid. 1-Octylnonyl 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl](2-hydroxyethyl)amino]octanoate can be used for researching drug delivery .
|
-
![1-Octylnonyl 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl](2-hydroxyethyl)amino]octanoate](//file.medchemexpress.com/product_pic/hy-147018.gif)
- HY-166997
-
|
|
Liposome
|
Others
|
|
AL-A12 is a short-chain amino lipid with high gene delivery efficiency and low toxicity, and can be used in drug delivery research .
|
-
- HY-167389
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG3000-ALK is a polylactic acid derivative that can form micelles in water. PLLA5000-PEG3000-ALK can be used in drug delivery research .
|
-
- HY-167410
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG2000-ALK is a polylactic acid derivative that can form micelles in water. PLLA10000-PEG2000-ALK can be used in drug delivery research .
|
-
- HY-167405
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG3000-ALK is a polylactic acid derivative that can form micelles in water. PLLA1000-PEG3000-ALK can be used in drug delivery research .
|
-
- HY-167388
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG5000-ALK is a polylactic acid derivative that can form micelles in water. PLLA5000-PEG5000-ALK can be used in drug delivery research .
|
-
- HY-167408
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG5000-ALK is a polylactic acid derivative that can form micelles in water. PLLA10000-PEG5000-ALK can be used in drug delivery research .
|
-
- HY-167409
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG3000-ALK is a polylactic acid derivative that can form micelles in water. PLLA10000-PEG3000-ALK can be used in drug delivery research .
|
-
- HY-167404
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG5000-ALK is a polylactic acid derivative that can form micelles in water. PLLA1000-PEG5000-ALK can be used in drug delivery research .
|
-
- HY-167392
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG5000-ALK is a polylactic acid derivative that can form micelles in water. PLLA4000-PEG5000-ALK can be used in drug delivery research .
|
-
- HY-167394
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG2000-ALK is a polylactic acid derivative that can form micelles in water. PLLA4000-PEG2000-ALK can be used in drug delivery research .
|
-
- HY-167391
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG1000-ALK is a polylactic acid derivative that can form micelles in water. PLLA5000-PEG1000-ALK can be used in drug delivery research .
|
-
- HY-167400
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG5000-ALK is a polylactic acid derivative that can form micelles in water. PLLA2000-PEG5000-ALK can be used in drug delivery research .
|
-
- HY-167403
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG1000-ALK is a polylactic acid derivative that can form micelles in water. PLLA2000-PEG1000-ALK can be used in drug delivery research .
|
-
- HY-167393
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG3000-ALK is a polylactic acid derivative that can form micelles in water. PLLA4000-PEG3000-ALK can be used in drug delivery research .
|
-
- HY-167390
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG2000-ALK is a polylactic acid derivative that can form micelles in water. PLLA5000-PEG2000-ALK can be used in drug delivery research .
|
-
- HY-167402
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG2000-ALK is a polylactic acid derivative that can form micelles in water. PLLA2000-PEG2000-ALK can be used in drug delivery research .
|
-
- HY-167396
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG5000-ALK is a polylactic acid derivative that can form micelles in water. PLLA3000-PEG5000-ALK can be used in drug delivery research .
|
-
- HY-167407
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG1000-ALK is a polylactic acid derivative that can form micelles in water. PLLA1000-PEG1000-ALK can be used in drug delivery research .
|
-
- HY-167401
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG3000-ALK is a polylactic acid derivative that can form micelles in water. PLLA2000-PEG3000-ALK can be used in drug delivery research .
|
-
- HY-167395
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG1000-ALK is a polylactic acid derivative that can form micelles in water. PLLA4000-PEG1000-ALK can be used in drug delivery research .
|
-
- HY-167398
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG2000-ALK is a polylactic acid derivative that can form micelles in water. PLLA3000-PEG2000-ALK can be used in drug delivery research .
|
-
- HY-167406
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG2000-ALK is a polylactic acid derivative that can form micelles in water. PLLA1000-PEG2000-ALK can be used in drug delivery research .
|
-
- HY-167397
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG3000-ALK is a polylactic acid derivative that can form micelles in water. PLLA3000-PEG3000-ALK can be used in drug delivery research .
|
-
- HY-167399
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG1000-ALK is a polylactic acid derivative that can form micelles in water. PLLA3000-PEG1000-ALK can be used in drug delivery research .
|
-
- HY-158709
-
|
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
Cho-es-Lys is a cationic lipid synthesized by coupling natural cholesterol and amino acids, which has high gene transfection efficiency. Cho-es-Lys can be used in drug delivery research .
|
-
- HY-168461
-
|
|
Bacterial
|
Infection
|
|
AK-968-11563024 is an inhibitor of marine V. vulnificus NAT [ (VIBVN)NAT] with an IC50 of 18.86 µM. NATs (Arylamine N-acetyltransferases) in marine V. vulnificus plays a role in drug metabolism, contributing to the development of drug resistance. Therefore, AK-968-11563024 can be utilized in research related to drug resistance .
|
-
- HY-159674
-
|
N-Tetamine-polySarcosine45-Maleimide
|
Biochemical Assay Reagents
|
Others
|
|
N-Tetamine-pSar45-Maleimide (N-Tetamine-polySarcosine45-Maleimide) is a pSar-lipid derivative. As a hydrophilic alternative to PEG, N-Tetamine-pSar45-Maleimide can be used in drug delivery research .
|
-
- HY-173381A
-
|
Cholesteryl biotinyl(polyethyleneglycol)-1000 carbamate
|
Biochemical Assay Reagents
|
Others
|
|
Cholesteryl-PEG1000-Biotin is a lipid product. Cholesteryl-PEG1000-Biotin is a cholesterol backbone attached to one side of a PEG unit and a Biotin unit on the other side. Biotin is an enzyme cofactor that can be used to label proteins, and PEG is a low-toxic, hydrophilic, water-soluble polymer. Cholesteryl-PEG1000-Biotin can be used for drug circulation time studies .
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-
- HY-W440699
-
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Biochemical Assay Reagents
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Others
|
|
Cholesterol-PEG-acid (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-acid (MW 3400) can be used in drug delivery research .
|
-
- HY-W591891
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-acid (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-acid (MW 1000) can be used in drug delivery research .
|
-
- HY-W440700
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-acid (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-acid (MW 5000) can be used in drug delivery research .
|
-
- HY-W440988
-
|
|
Liposome
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Others
|
|
DOPE-mPEG, MW 2000 is a phospholipid polydisperse PEG (or DOPE liposome), can be used for preparation of targeted delivery of liposomal drug and giant unilamellar vesicles (GUVs). DOPE-mPEG, MW 2000 significantly reduces the pH-sensitivity of the liposome in a concentration dependent manner .
|
-
- HY-W440709
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-alcohol (MW 10000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-alcohol (MW 10000) can be used in drug delivery research .
|
-
- HY-W591914
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-methoxy (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-methoxy (MW 5000) can be used in drug delivery research .
|
-
- HY-W440692
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-amine (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-amine (MW 5000) can be used in drug delivery research .
|
-
- HY-W440718
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-Mal (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Mal (MW 1000) can be used in drug delivery research .
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-
- HY-W440695
-
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|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-azide (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-azide (MW 3400) can be used in drug delivery research .
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-
- HY-W440726
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-Vinylsulfone (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Vinylsulfone (MW 1000) can be used in drug delivery research .
|
-
- HY-W440696
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-azide (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-azide (MW 5000) can be used in drug delivery research .
|
-
- HY-W591912
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-methoxy (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-methoxy (MW 1000) can be used in drug delivery research .
|
-
- HY-W440723
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-Thiol (MW 2000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Thiol (MW 2000) can be used in drug delivery research .
|
-
- HY-W440707
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-alcohol (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-alcohol (MW 3400) can be used in drug delivery research .
|
-
- HY-W440721
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-Mal (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Mal (MW 5000) can be used in drug delivery research .
|
-
- HY-W440728
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-Vinylsulfone (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Vinylsulfone (MW 3400) can be used in drug delivery research .
|
-
- HY-W440717
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-Folate (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Folate (MW 5000) can be used in drug delivery research .
|
-
- HY-W440716
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-Folate (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Folate (MW 3400) can be used in drug delivery research .
|
-
- HY-W440697
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-NHS (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 1000) can be used in drug delivery research .
|
-
- HY-W440702
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-NHS (MW 2000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 2000) can be used in drug delivery research .
|
-
- HY-W440725
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-Thiol (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Thiol (MW 5000) can be used in drug delivery research .
|
-
- HY-W440693
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-azide (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-azide (MW 1000) can be used in drug delivery research .
|
-
- HY-W440691
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-amine (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-amine (MW 3400) can be used in drug delivery research .
|
-
- HY-W440713
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-Biotin (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Biotin (MW 5000) can be used in drug delivery research .
|
-
- HY-W440705
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-alcohol (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-alcohol (MW 1000) can be used in drug delivery research .
|
-
- HY-W440720
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-Mal (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Mal (MW 3400) can be used in drug delivery research .
|
-
- HY-W440714
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-Folate (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Folate (MW 1000) can be used in drug delivery research .
|
-
- HY-W440708
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-alcohol (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-alcohol (MW 5000) can be used in drug delivery research .
|
-
- HY-W440703
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-NHS (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 3400) can be used in drug delivery research .
|
-
- HY-W440712
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-Biotin (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Biotin (MW 3400) can be used in drug delivery research .
|
-
- HY-W440729
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-Vinylsulfone (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Vinylsulfone (MW 5000) can be used in drug delivery research .
|
-
- HY-145941
-
|
2-Acryloxyethyltrimethylammonium chloride
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
|
AETA (2-Acryloxyethyltrimethylammonium chloride) can be used for the synthesis of hydrophilic polymers and hydrogels. Hydrogels are used for membranes, catheters, contact lenses, and drug delivery systems .
|
-
- HY-167054
-
|
PLLA2000-PEG2000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG2000-VS (PLLA2000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167055
-
|
PLLA4000-PEG2000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG2000-VS (PLLA4000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167020
-
|
PLGA3000-PEG1000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA3000-PEG1000-VS (PLGA3000-PEG1000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167034
-
|
PLGA5000-PEG1000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA5000-PEG1000-VS (PLGA5000-PEG1000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167006
-
|
PLGA10000-PEG3000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA10000-PEG3000-VS (PLGA10000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167019
-
|
PLGA2000-PEG5000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA2000-PEG5000-VS (PLGA2000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167027
-
|
PLGA3000-PEG5000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA3000-PEG5000-VS (PLGA3000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167051
-
|
PLLA1000-PEG5000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG5000-VS (PLLA1000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167030
-
|
PLGA4000-PEG2000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA4000-PEG2000-VS (PLGA4000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167032
-
|
PLGA4000-PEG3000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA4000-PEG3000-VS (PLGA4000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167062
-
|
PLLA2000-PEG3000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG3000-VS (PLLA2000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167005
-
|
PLGA10000-PEG2000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA10000-PEG2000-VS (PLGA10000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167052
-
|
PLLA2000-PEG1000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG1000-VS (PLLA2000-PEG1000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167038
-
|
PLGA5000-PEG5000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA5000-PEG5000-VS (PLGA5000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167018
-
|
PLGA2000-PEG3000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA2000-PEG3000-VS (PLGA2000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167485
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG5000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA1000-PEG5000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167013
-
|
PLGA1000-PEG5000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA1000-PEG5000-VS (PLGA1000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167474
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG3000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA4000-PEG3000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167469
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG5000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA5000-PEG5000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167492
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG1000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA10000-PEG1000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167057
-
|
PLLA3000-PEG5000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG5000-VS (PLLA3000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167482
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG3000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA2000-PEG3000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167040
-
|
PLLA10000-PEG1000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG1000-VS (PLLA10000-PEG1000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167037
-
|
PLGA5000-PEG3000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA5000-PEG3000-VS (PLGA5000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167473
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG5000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA4000-PEG5000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167475
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG2000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA4000-PEG2000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167480
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG1000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA3000-PEG1000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167491
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG2000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA10000-PEG2000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167043
-
|
PLLA10000-PEG3000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG3000-VS (PLLA10000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167471
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG2000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA5000-PEG2000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167477
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG5000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA3000-PEG5000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167008
-
|
PLGA1000-PEG1000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA1000-PEG1000-VS (PLGA1000-PEG1000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167058
-
|
PLLA3000-PEG3000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG3000-VS (PLLA3000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167053
-
|
PLLA4000-PEG3000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG3000-VS (PLLA4000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167033
-
|
PLGA4000-PEG5000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA4000-PEG5000-VS (PLGA4000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167049
-
|
PLLA4000-PEG5000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG5000-VS (PLLA4000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167048
-
|
PLLA1000-PEG2000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG2000-VS (PLLA1000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167488
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG1000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA1000-PEG1000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167041
-
|
PLLA5000-PEG3000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG3000-VS (PLLA5000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167059
-
|
PLLA3000-PEG2000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG2000-VS (PLLA3000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167486
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG3000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA1000-PEG3000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167046
-
|
PLLA1000-PEG1000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG1000-VS (PLLA1000-PEG1000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167472
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG1000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA5000-PEG1000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167047
-
|
PLLA5000-PEG1000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG1000-VS (PLLA5000-PEG1000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167490
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG3000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA10000-PEG3000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167050
-
|
PLLA1000-PEG3000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG3000-VS (PLLA1000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167470
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG3000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA5000-PEG3000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167029
-
|
PLGA4000-PEG1000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA4000-PEG1000-VS (PLGA4000-PEG1000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167484
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG1000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA2000-PEG1000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167039
-
|
PLLA5000-PEG5000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG5000-VS (PLLA5000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167044
-
|
PLLA5000-PEG2000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG2000-VS (PLLA5000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167009
-
|
PLGA1000-PEG2000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA1000-PEG2000-VS (PLGA1000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167026
-
|
PLGA3000-PEG3000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA3000-PEG3000-VS (PLGA3000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167060
-
|
PLLA3000-PEG1000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG1000-VS (PLLA3000-PEG1000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167014
-
|
PLGA2000-PEG1000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA2000-PEG1000-VS (PLGA2000-PEG1000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167479
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG2000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA3000-PEG2000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167487
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG2000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA1000-PEG2000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167483
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG2000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA2000-PEG2000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167478
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG3000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA3000-PEG3000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167061
-
|
PLLA2000-PEG5000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG5000-VS (PLLA2000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167489
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG5000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA10000-PEG5000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167023
-
|
PLGA3000-PEG2000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA3000-PEG2000-VS (PLGA3000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167481
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG5000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA2000-PEG5000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167010
-
|
PLGA1000-PEG3000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA1000-PEG3000-VS (PLGA1000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167056
-
|
PLLA4000-PEG1000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG1000-VS (PLLA4000-PEG1000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167045
-
|
PLLA10000-PEG5000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG5000-VS (PLLA10000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167035
-
|
PLGA5000-PEG2000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLGA5000-PEG2000-VS (PLGA5000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167476
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG1000-RhB is a terminal rhodamine-labeled polylactic acid derivative. PLLA4000-PEG1000-RhB can be used to label nanomicelles for real-time monitoring of drug release in vivo .
|
-
- HY-167042
-
|
PLLA10000-PEG2000-Vinylsulfone
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG2000-VS (PLLA10000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
|
-
- HY-167545
-
|
POPE
|
Liposome
Biochemical Assay Reagents
|
Others
|
|
1-Palmitoyl-2-oleoylphosphatidylethanolamine (POPE) is a PE-based synthetic phospholipid that can intercalate with other amphiphilic molecules to form stable bilayers at physiological pH. 1-Palmitoyl-2-oleoylphosphatidylethanolamine can be used in drug delivery research .
|
-
- HY-167305
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG1000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA3000-PEG1000-Thiol can be used in drug delivery research .
|
-
- HY-167307
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG3000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA2000-PEG3000-Thiol can be used in drug delivery research .
|
-
- HY-167306
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG5000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA2000-PEG5000-Thiol can be used in drug delivery research .
|
-
- HY-167299
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG3000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA4000-PEG3000-Thiol can be used in drug delivery research .
|
-
- HY-167295
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG3000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA5000-PEG3000-Thiol can be used in drug delivery research .
|
-
- HY-167311
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG3000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA1000-PEG3000-Thiol can be used in drug delivery research .
|
-
- HY-167316
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG2000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA10000-PEG2000-Thiol can be used in drug delivery research .
|
-
- HY-167304
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG2000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA3000-PEG2000-Thiol can be used in drug delivery research .
|
-
- HY-167301
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG1000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA4000-PEG1000-Thiol can be used in drug delivery research .
|
-
- HY-167309
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG1000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA2000-PEG1000-Thiol can be used in drug delivery research .
|
-
- HY-167296
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG2000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA5000-PEG2000-Thiol can be used in drug delivery research .
|
-
- HY-167297
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG1000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA5000-PEG1000-Thiol can be used in drug delivery research .
|
-
- HY-167300
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG2000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA4000-PEG2000-Thiol can be used in drug delivery research .
|
-
- HY-167315
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG3000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA10000-PEG3000-Thiol can be used in drug delivery research .
|
-
- HY-167317
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG1000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA10000-PEG1000-Thiol can be used in drug delivery research .
|
-
- HY-167303
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG3000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA3000-PEG3000-Thiol can be used in drug delivery research .
|
-
- HY-167314
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG5000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA10000-PEG5000-Thiol can be used in drug delivery research .
|
-
- HY-167312
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG2000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA1000-PEG2000-Thiol can be used in drug delivery research .
|
-
- HY-167308
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG2000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA2000-PEG2000-Thiol can be used in drug delivery research .
|
-
- HY-167294
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG5000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA5000-PEG5000-Thiol can be used in drug delivery research .
|
-
- HY-167302
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG5000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA3000-PEG5000-Thiol can be used in drug delivery research .
|
-
- HY-167310
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG5000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA1000-PEG5000-Thiol can be used in drug delivery research .
|
-
- HY-167298
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG5000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA4000-PEG5000-Thiol can be used in drug delivery research .
|
-
- HY-167313
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG1000-Thiol is a polylactic acid derivative that forms micelles in water and initiates biodegradation by attacking ester bonds through hydrolysis. PLLA1000-PEG1000-Thiol can be used in drug delivery research .
|
-
- HY-151226
-
|
GMS
|
Liposome
|
Cancer
|
|
Glyceryl monostearate (GMS) is a single-tailed lipidic monoglyceride that can be used to synthesize nanoliposomes for drug delivery .
|
-
- HY-156862
-
|
|
Angiotensin Receptor
|
Others
|
|
(+)-Chloroquine is a aminoquinoline drug impairs in vitro the terminal glycosylation of angiotensin-converting enzyme 2 (ACE-2) .
|
-
- HY-B0803
-
|
Benflumetol
|
Parasite
|
Infection
|
|
Lumefantrine is an active antimalarial molecule used in combination with Artemether as a first- and second-line antimalarial drug with oral activity .
|
-
- HY-B1629
-
|
|
Drug Intermediate
|
Infection
|
|
Dichlorodiphenylmethane is a drug intermediate, which is widely used in the fields of pesticide, dye and medicine .
|
-
- HY-164637
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Aniline-PEG3-C1-Boc (compound D-1) is an intermediate of cytotoxic drug linker polymer. Aniline-PEG3-C1-Boc can be used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W888515
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-PCL is a biodegradable, biocompatible, and semi-crystalline copolymer having a very low glass transition temperature. mPEG-PCL can be used as synthetic material for biomedical and drug delivery .
|
-
- HY-167324
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG2000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA4000-PEG2000-SPDP can be used in drug delivery research .
|
-
- HY-167339
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG3000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA10000-PEG3000-SPDP can be used in drug delivery research .
|
-
- HY-167330
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG5000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA2000-PEG5000-SPDP can be used in drug delivery research .
|
-
- HY-167325
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG1000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA4000-PEG1000-SPDP can be used in drug delivery research .
|
-
- HY-167335
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG3000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA1000-PEG3000-SPDP can be used in drug delivery research .
|
-
- HY-167338
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG5000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA10000-PEG5000-SPDP can be used in drug delivery research .
|
-
- HY-167341
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG1000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA10000-PEG1000-SPDP can be used in drug delivery research .
|
-
- HY-167336
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG2000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA1000-PEG2000-SPDP can be used in drug delivery research .
|
-
- HY-167333
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG1000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA2000-PEG1000-SPDP can be used in drug delivery research .
|
-
- HY-167331
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG3000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA2000-PEG3000-SPDP can be used in drug delivery research .
|
-
- HY-167332
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG2000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA2000-PEG2000-SPDP can be used in drug delivery research .
|
-
- HY-167321
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG1000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA5000-PEG1000-SPDP can be used in drug delivery research .
|
-
- HY-167328
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG2000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA3000-PEG2000-SPDP can be used in drug delivery research .
|
-
- HY-167320
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG2000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA5000-PEG2000-SPDP can be used in drug delivery research .
|
-
- HY-167327
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG3000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA3000-PEG3000-SPDP can be used in drug delivery research .
|
-
- HY-167326
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG5000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA3000-PEG5000-SPDP can be used in drug delivery research .
|
-
- HY-167334
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG5000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA1000-PEG5000-SPDP can be used in drug delivery research .
|
-
- HY-167318
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG5000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA5000-PEG5000-SPDP can be used in drug delivery research .
|
-
- HY-167323
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG3000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA4000-PEG3000-SPDP can be used in drug delivery research .
|
-
- HY-167322
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG5000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA4000-PEG5000-SPDP can be used in drug delivery research .
|
-
- HY-167340
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG2000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA10000-PEG2000-SPDP can be used in drug delivery research .
|
-
- HY-167337
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG1000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA1000-PEG1000-SPDP can be used in drug delivery research .
|
-
- HY-167319
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG3000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA5000-PEG3000-SPDP can be used in drug delivery research .
|
-
- HY-167329
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG1000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA3000-PEG1000-SPDP can be used in drug delivery research .
|
-
- HY-167412
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG2000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA5000-PEG2000-FOL can be used in drug delivery research .
|
-
- HY-167415
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG5000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA10000-PEG5000-FOL can be used in drug delivery research .
|
-
- HY-167413
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA20000-PEG5000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA20000-PEG5000-FOL can be used in drug delivery research .
|
-
- HY-167411
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG5000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA5000-PEG5000-FOL can be used in drug delivery research .
|
-
- HY-167416
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG2000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA10000-PEG2000-FOL can be used in drug delivery research .
|
-
- HY-167414
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA20000-PEG2000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA20000-PEG2000-FOL can be used in drug delivery research .
|
-
- HY-109796
-
|
|
Bacterial
|
Infection
|
|
NIK250 is a potent multiple drug resistance (MDR) reversal agent that inhibits P-glycoprotein .
|
-
- HY-W583868
-
|
1,2-POPE; 16:0-18:1 PE
|
Liposome
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Others
|
|
1-Palmitoyl-2-oleoyl-sn-glycero-3-PE (1,2-POPE; 16:0-18:1 PE) is a phosphatidylethanolamine (PE) lipid. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can induce lipid bilayer to form a hexagonal phase (HII) structure in an acidic environment and promote membrane fusion. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can enhance the endosomal escape ability of lipid nanoparticles (LNPs) and improve the cellular delivery efficiency of nucleic acid drugs such as mRNA. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can be used for LNP carrier targeting of gene therapy and mRNA vaccines .
|
-
- HY-167428
-
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Biochemical Assay Reagents
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Others
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|
PLLA3000-PEG1000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA3000-PEG1000-NH2 can be used in drug delivery research .
|
-
- HY-167425
-
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Biochemical Assay Reagents
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Others
|
|
PLLA3000-PEG5000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA3000-PEG5000-NH2 can be used in drug delivery research .
|
-
- HY-167427
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG2000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA3000-PEG2000-NH2 can be used in drug delivery research .
|
-
- HY-167440
-
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|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG3000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA10000-PEG3000-NH2 can be used in drug delivery research .
|
-
- HY-167441
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG2000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA10000-PEG2000-NH2 can be used in drug delivery research .
|
-
- HY-167424
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG1000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA4000-PEG1000-NH2 can be used in drug delivery research .
|
-
- HY-167421
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG5000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA4000-PEG5000-NH2 can be used in drug delivery research .
|
-
- HY-167437
-
|
|
Biochemical Assay Reagents
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Others
|
|
PLLA1000-PEG2000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA1000-PEG2000-NH2 can be used in drug delivery research .
|
-
- HY-167433
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG1000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA2000-PEG1000-NH2 can be used in drug delivery research .
|
-
- HY-167420
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG1000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA5000-PEG1000-NH2 can be used in drug delivery research .
|
-
- HY-167431
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG3000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA2000-PEG3000-NH2 can be used in drug delivery research .
|
-
- HY-167439
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG5000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA10000-PEG5000-NH2 can be used in drug delivery research .
|
-
- HY-167435
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG5000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA1000-PEG5000-NH2 can be used in drug delivery research .
|
-
- HY-167438
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG1000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA1000-PEG1000-NH2 can be used in drug delivery research .
|
-
- HY-167442
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG1000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA10000-PEG1000-NH2 can be used in drug delivery research .
|
-
- HY-167434
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA20000-PEG5000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA20000-PEG5000-NH2 can be used in drug delivery research .
|
-
- HY-167419
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG2000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA5000-PEG2000-NH2 can be used in drug delivery research .
|
-
- HY-167430
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG5000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA2000-PEG5000-NH2 can be used in drug delivery research .
|
-
- HY-167423
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG2000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA4000-PEG2000-NH2 can be used in drug delivery research .
|
-
- HY-167418
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG3000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA5000-PEG3000-NH2 can be used in drug delivery research .
|
-
- HY-167436
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG3000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA1000-PEG3000-NH2 can be used in drug delivery research .
|
-
- HY-167432
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG2000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA2000-PEG2000-NH2 can be used in drug delivery research .
|
-
- HY-167426
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG3000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA3000-PEG3000-NH2 can be used in drug delivery research .
|
-
- HY-167429
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA30000-PEG5000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA30000-PEG5000-NH2 can be used in drug delivery research .
|
-
- HY-167422
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG3000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA4000-PEG3000-NH2 can be used in drug delivery research .
|
-
- HY-167417
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG5000-NH2 is a block copolymer based on polylactic acid derivatives that can self-assemble in water. PLLA5000-PEG5000-NH2 can be used in drug delivery research .
|
-
- HY-200444
-
|
|
Liposome
|
Others
|
|
Lipid catechol is a lipid that forms lipid prodrug nanoassemblies (LPNA) with boronic acid-containing compounds. Lipid catechol is promising for research of drug delivery .
|
-
- HY-W440832
-
|
DSPE-PEG(2000) Azide
|
Liposome
|
Infection
|
|
DSPE-PEG-Azide (MW 2000) is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery . DSPE-PEG-Azide (MW 2000) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-167370
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG5000-BIO is a polylactic acid derivative that can form micelles in water. In addition, PLLA5000-PEG5000-BIO can bind tightly to avidin or streptavidin for protein labeling. PLLA5000-PEG5000-BIO can be used in drug delivery research .
|
-
- HY-167383
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG2000-BIO is a polylactic acid derivative that can form micelles in water. In addition, PLLA1000-PEG2000-BIO can bind tightly to avidin or streptavidin for protein labeling. PLLA1000-PEG2000-BIO can be used in drug delivery research .
|
-
- HY-167384
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG1000-BIO is a polylactic acid derivative that can form micelles in water. In addition, PLLA1000-PEG1000-BIO can bind tightly to avidin or streptavidin for protein labeling. PLLA1000-PEG1000-BIO can be used in drug delivery research .
|
-
- HY-167376
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG5000-BIO is a polylactic acid derivative that can form micelles in water. In addition, PLLA3000-PEG5000-BIO can bind tightly to avidin or streptavidin for protein labeling. PLLA3000-PEG5000-BIO can be used in drug delivery research .
|
-
- HY-167373
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG5000-BIO is a polylactic acid derivative that can form micelles in water. In addition, PLLA4000-PEG5000-BIO can bind tightly to avidin or streptavidin for protein labeling. PLLA4000-PEG5000-BIO can be used in drug delivery research .
|
-
- HY-167379
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG5000-BIO is a polylactic acid derivative that can form micelles in water. In addition, PLLA2000-PEG5000-BIO can bind tightly to avidin or streptavidin for protein labeling. PLLA2000-PEG5000-BIO can be used in drug delivery research .
|
-
- HY-167381
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG1000-BIO is a polylactic acid derivative that can form micelles in water. In addition, PLLA2000-PEG1000-BIO can bind tightly to avidin or streptavidin for protein labeling. PLLA2000-PEG1000-BIO can be used in drug delivery research .
|
-
- HY-167372
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG1000-BIO is a polylactic acid derivative that can form micelles in water. In addition, PLLA5000-PEG1000-BIO can bind tightly to avidin or streptavidin for protein labeling. PLLA5000-PEG1000-BIO can be used in drug delivery research .
|
-
- HY-167377
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG2000-BIO is a polylactic acid derivative that can form micelles in water. In addition, PLLA3000-PEG2000-BIO can bind tightly to avidin or streptavidin for protein labeling. PLLA3000-PEG2000-BIO can be used in drug delivery research .
|
-
- HY-167382
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG5000-BIO is a polylactic acid derivative that can form micelles in water. In addition, PLLA1000-PEG5000-BIO can bind tightly to avidin or streptavidin for protein labeling. PLLA1000-PEG5000-BIO can be used in drug delivery research .
|
-
- HY-167380
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG2000-BIO is a polylactic acid derivative that can form micelles in water. In addition, PLLA2000-PEG2000-BIO can bind tightly to avidin or streptavidin for protein labeling. PLLA2000-PEG2000-BIO can be used in drug delivery research .
|
-
- HY-167378
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG1000-BIO is a polylactic acid derivative that can form micelles in water. In addition, PLLA3000-PEG1000-BIO can bind tightly to avidin or streptavidin for protein labeling. PLLA3000-PEG1000-BIO can be used in drug delivery research .
|
-
- HY-167385
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG5000-BIO is a polylactic acid derivative that can form micelles in water. In addition, PLLA10000-PEG5000-BIO can bind tightly to avidin or streptavidin for protein labeling. PLLA10000-PEG5000-BIO can be used in drug delivery research .
|
-
- HY-167374
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG2000-BIO is a polylactic acid derivative that can form micelles in water. In addition, PLLA4000-PEG2000-BIO can bind tightly to avidin or streptavidin for protein labeling. PLLA4000-PEG2000-BIO can be used in drug delivery research .
|
-
- HY-167387
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG1000-BIO is a polylactic acid derivative that can form micelles in water. In addition, PLLA10000-PEG1000-BIO can bind tightly to avidin or streptavidin for protein labeling. PLLA10000-PEG1000-BIO can be used in drug delivery research .
|
-
- HY-167386
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG2000-BIO is a polylactic acid derivative that can form micelles in water. In addition, PLLA10000-PEG2000-BIO can bind tightly to avidin or streptavidin for protein labeling. PLLA10000-PEG2000-BIO can be used in drug delivery research .
|
-
- HY-167375
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG1000-BIO is a polylactic acid derivative that can form micelles in water. In addition, PLLA4000-PEG1000-BIO can bind tightly to avidin or streptavidin for protein labeling. PLLA4000-PEG1000-BIO can be used in drug delivery research .
|
-
- HY-167371
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG2000-BIO is a polylactic acid derivative that can form micelles in water. In addition, PLLA5000-PEG2000-BIO can bind tightly to avidin or streptavidin for protein labeling. PLLA5000-PEG2000-BIO can be used in drug delivery research .
|
-
- HY-167132
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA6000-PEG4000-PLLA6000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA6000-PEG4000-PLLA6000 can be used in drug delivery research .
|
-
- HY-167356
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG2000-PLLA3000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA3000-PEG2000-PLLA3000 can be used in drug delivery research .
|
-
- HY-167366
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG4000-PLLA1000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA1000-PEG4000-PLLA1000 can be used in drug delivery research .
|
-
- HY-167361
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG3000-PLLA2000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA2000-PEG3000-PLLA2000 can be used in drug delivery research .
|
-
- HY-167357
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG1000-PLLA3000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA3000-PEG1000-PLLA3000 can be used in drug delivery research .
|
-
- HY-167118
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG6000-PLLA5000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA5000-PEG6000-PLLA5000 can be used in drug delivery research .
|
-
- HY-167343
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG3000-PLLA5000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA5000-PEG3000-PLLA5000 can be used in drug delivery research .
|
-
- HY-167363
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG1000-PLLA2000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA2000-PEG1000-PLLA2000 can be used in drug delivery research .
|
-
- HY-167137
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA6000-PEG6000-PLLA6000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA6000-PEG6000-PLLA6000 can be used in drug delivery research .
|
-
- HY-167352
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG8000-PLLA3000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA3000-PEG8000-PLLA3000 can be used in drug delivery research .
|
-
- HY-167128
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA8000-PEG8000-PLLA8000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA8000-PEG8000-PLLA8000 can be used in drug delivery research .
|
-
- HY-167139
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA8000-PEG1000-PLLA8000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA8000-PEG1000-PLLA8000 can be used in drug delivery research .
|
-
- HY-167360
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG4000-PLLA2000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA2000-PEG4000-PLLA2000 can be used in drug delivery research .
|
-
- HY-167126
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA6000-PEG3000-PLLA6000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA6000-PEG3000-PLLA6000 can be used in drug delivery research .
|
-
- HY-167365
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG6000-PLLA1000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA1000-PEG6000-PLLA1000 can be used in drug delivery research .
|
-
- HY-167345
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG1000-PLLA5000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA5000-PEG1000-PLLA5000 can be used in drug delivery research .
|
-
- HY-167353
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG6000-PLLA3000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA3000-PEG6000-PLLA3000 can be used in drug delivery research .
|
-
- HY-167350
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG2000-PLLA4000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA4000-PEG2000-PLLA4000 can be used in drug delivery research .
|
-
- HY-167134
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA8000-PEG4000-PLLA8000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA8000-PEG4000-PLLA8000 can be used in drug delivery research .
|
-
- HY-167120
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA6000-PEG1000-PLLA6000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA6000-PEG1000-PLLA6000 can be used in drug delivery research .
|
-
- HY-167358
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG8000-PLLA2000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA2000-PEG8000-PLLA2000 can be used in drug delivery research .
|
-
- HY-167367
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG3000-PLLA1000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA1000-PEG3000-PLLA1000 can be used in drug delivery research .
|
-
- HY-167344
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG2000-PLLA5000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA5000-PEG2000-PLLA5000 can be used in drug delivery research .
|
-
- HY-167349
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG3000-PLLA4000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA4000-PEG3000-PLLA4000 can be used in drug delivery research .
|
-
- HY-167364
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG8000-PLLA1000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA1000-PEG8000-PLLA1000 can be used in drug delivery research .
|
-
- HY-167124
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA6000-PEG2000-PLLA6000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA6000-PEG2000-PLLA6000 can be used in drug delivery research .
|
-
- HY-167369
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG1000-PLLA1000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA1000-PEG1000-PLLA1000 can be used in drug delivery research .
|
-
- HY-167346
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG8000-PLLA4000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA4000-PEG8000-PLLA4000 can be used in drug delivery research .
|
-
- HY-167359
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG6000-PLLA2000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA2000-PEG6000-PLLA2000 can be used in drug delivery research .
|
-
- HY-167351
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG1000-PLLA4000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA4000-PEG1000-PLLA4000 can be used in drug delivery research .
|
-
- HY-167130
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA8000-PEG6000-PLLA8000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA8000-PEG6000-PLLA8000 can be used in drug delivery research .
|
-
- HY-167354
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG4000-PLLA3000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA3000-PEG4000-PLLA3000 can be used in drug delivery research .
|
-
- HY-167342
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG4000-PLLA5000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA5000-PEG4000-PLLA5000 can be used in drug delivery research .
|
-
- HY-167140
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA6000-PEG8000-PLLA6000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA6000-PEG8000-PLLA6000 can be used in drug delivery research .
|
-
- HY-167355
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG3000-PLLA3000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA3000-PEG3000-PLLA3000 can be used in drug delivery research .
|
-
- HY-167362
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG2000-PLLA2000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA2000-PEG2000-PLLA2000 can be used in drug delivery research .
|
-
- HY-167119
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG8000-PLLA5000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA5000-PEG8000-PLLA5000 can be used in drug delivery research .
|
-
- HY-167347
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG6000-PLLA4000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA4000-PEG6000-PLLA4000 can be used in drug delivery research .
|
-
- HY-167368
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG2000-PLLA1000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA1000-PEG2000-PLLA1000 can be used in drug delivery research .
|
-
- HY-167138
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA8000-PEG2000-PLLA8000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA8000-PEG2000-PLLA8000 can be used in drug delivery research .
|
-
- HY-167348
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG4000-PLLA4000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA4000-PEG4000-PLLA4000 can be used in drug delivery research .
|
-
- HY-167136
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA8000-PEG3000-PLLA8000 is an amphiphilic triblock polymer based on polylactic acid derivatives that improves the specificity and cell affinity of PLA-based biomaterials. PLLA8000-PEG3000-PLLA8000 can be used in drug delivery research .
|
-
- HY-159194
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-Cy5.5 is a CY5.5 labeled DSPE-PEG 2000 for drug delivery and imaging .
|
-
- HY-145767A
-
|
|
Drug Intermediate
|
Others
|
|
SN-38-CO-DMEDA TFA is the intermediate product for synthesizing antibody-conjugated drug LND1035 .
|
-
- HY-D2401F
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-Polystyrene microsphere (100 nm) is a Cy5 (HY-D0821)-labeled microsphere that can be used for bioimaging and drug delivery .
|
-
- HY-161602
-
|
|
EGFR
|
Cancer
|
|
EGFR/HER2-IN-13 (Compd 38) is an inhibitor of mutant EGFR/HER2s which are resistant to other drugs. EGFR/HER2-IN-13 can be used for cancer research .
|
-
- HY-161603
-
|
|
EGFR
|
Cancer
|
|
EGFR/HER2-IN-14 (Compd 46) is an inhibitor of mutant EGFR/HER2s which are resistant to other drugs. EGFR/HER2-IN-14 can be used for cancer research .
|
-
- HY-162926
-
|
|
Bacterial
|
Infection
|
|
Antituberculosis agent-12 (compound 3408) is a narrow-spectrum antituberculosis prodrug phosphate that has the ability to inhibit drug-resistant tuberculosis infection .
|
-
- HY-W414069
-
|
|
Endogenous Metabolite
Liposome
|
Others
|
|
Thiocholesterol is a member of the class of cholesteric liquid crystals (CLCs) that can be used to synthesis cationic lipid. Thiocholesterol is a stronger stabilizer of silver nanoparticles (SNPs). Thiocholesterol can be used for plasma membrane research and drug delivery .
|
-
- HY-W440698
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG-Acid (MW 2000) is a polydisperse PEG derivative which can be used to create liposome as drug carrier for delivering therapeutic agents into tissues.
|
-
- HY-158255A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-PLGA (22500-26500) is a biodegradable polymer composed of methyl polyethylene glycol (mPEG) and poly(lactic-co-glycolic acid) (PLGA). mPEG-PLGA (22500-26500) can be used in drug delivery systems .
|
-
- HY-W763806
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Zein is a plant protein‐based polymer, can be used to prepare nanofibrous mats through electrospun. Zein has good cell compatibility and easy fabrication ability, and can be used in drug delivery systems .
|
-
- HY-N0322BR
-
|
|
Reference Standards
Liposome
Endogenous Metabolite
|
Others
|
Cholesterol (Excipient) (Standard) is the analytical standard of Cholesterol (Excipient) (HY-N0322B). This product is intended for research and analytical applications. Cholesterol Excipient is a component of the cell membrane and a precursor of some hormones, vitamin D and bile acid, with oral activity. Cholesterol Excipient is a drug delivery carrier based on the lipid environment of the cell membrane. Due to its amphiphilicity, good biocompatibility and biodegradability, it can be used as an excipient in drug preparations. Cholesterol Excipient can self-assemble into delivery systems such as micelles, nanoparticles, and liposomes, and achieve controlled drug release by regulating membrane fluidity or responding to the microenvironment. It has the characteristics of high drug loading efficiency and good biocompatibility. Cholesterol Excipient is mainly used for research in the fields of targeted delivery of anticancer, antibacterial, antiviral drugs and treatment of skin diseases.
Cholesterol itself is also an endogenous regulator involved in the cleavage of amyloid precursor protein (APP) mediated by β-secretase and intestinal absorption, as well as an endogenous estrogen-related receptor α (ERRα) agonist. Cholesterol affects the subcellular localization of APP processing enzymes by regulating the cell membrane lipid environment, which can promote the production of β-amyloid protein and its adsorption and removal by probiotics. It is used to study the pathogenesis of Alzheimer's disease (AD) and the cholesterol-lowering function of probiotics[1][2][3][4][5].
|
-
- HY-155902B
-
|
Maleimide-PEG-Hydroxy (MW 1000)
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-OH (MW 1000) was used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
|
-
- HY-139818
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-PLA (PEG MW 3000 & PLA MW 70,000) is a block copolymer, which can be used to preparenanoparticles and micelles for targeted drug delivery .
|
-
- HY-173590
-
|
|
Histone Demethylase
|
Cancer
|
|
AW4 is a LSD1 inhibitor. AW4 inhibits LSD1 ΔTTAS activity in H3K4me2 demethylation assays. AW4 can be used for research of drug resistance .
|
-
- HY-155902
-
|
Maleimide-PEG-Hydroxy (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-OH (MW 5000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
|
-
- HY-155902A
-
|
Maleimide-PEG-Hydroxy (MW 2000)
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-OH (MW 2000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
|
-
- HY-171060
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Mc-Pro-PAB-MMAE is a Drug-Linker Conjugate for ADC. Mc-Pro-PAB-MMAE consists of Monomethyl auristatin E (HY-15162) and a linker. Mc-Pro-PAB-MMAE can be used for synthesis of ADCs .
|
-
- HY-W013751
-
|
N-Fmoc-glycyl-L-valine
|
Drug Intermediate
|
Others
|
|
Fmoc-Gly-Val-OH (N-Fmoc-glycyl-L-valine) is a glycyl valine derivative, can be used for the synthesis of drugs or other compounds .
|
-
- HY-119108
-
|
BOF-A2
|
Drug Derivative
|
Cancer
|
|
Emitefur is an orally active and potent anticancer drug. Emitefur can be used for advanced gastric cancer patients .
|
-
- HY-153892
-
-
- HY-131955
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-aminooxy-PEG2-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-139819
-
|
|
Biochemical Assay Reagents
|
Others
|
|
MPEG-PLA (PEG MW 3000 & PLA MW 50,000) is a block copolymer, which can be used to preparenanoparticles for targeted drug delivery .
|
-
- HY-105939
-
|
LM 22070
|
PGE synthase
|
Inflammation/Immunology
|
|
Isofezolac (LM 22070) is a non-steroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin-synthetase. Isofezolac anti-inflammatory, and antipyretic properties .
|
-
- HY-160453
-
|
|
Others
|
Others
|
|
MC-Gly-Gly-Phe-Gly-NH-CH2-O-cyclopropane-CH2COOH is a camptothecin derivative. MC-Gly-Gly-Phe-Gly-NH-CH2-O-cyclopropane-CH2COOH can be used for antibody drug conjugate (ADC) .
|
-
- HY-159709
-
|
|
Liposome
|
Others
|
|
VL-422 is an ionizable cationic lipid that can be used for lipid nanoparticle (LNP) and drug delivery research .
|
-
- HY-150242A
-
|
|
Liposome
|
Others
|
|
Cbz-Ala-Ala-Asn TFA is a peptide that designed based on the sequence of the substrate of legumain. Legumain is a cysteine protease. Cbz-Ala-Ala-Asn TFA can be applied as a scaffold for drug delivery .
|
-
- HY-166648A
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Maleimide (ammonium) (MW 2000) has DSPE phospholipids and maleimide to prepare nanostructured lipid carriers. DSPE-PEG-Maleimide (ammonium) (MW 2000) can be used in drug delivery research .
|
-
- HY-W440548
-
|
Ethylene diacrylate
|
Biochemical Assay Reagents
|
Others
|
|
Ethylene glycol diacrylate (Ethylene diacrylate) is a cross-linking homobifunctional reagent. Ethylene glycol diacrylate can be polymerized to form poly(ethylene glycol) diacrylate for drug delivery .
|
-
- HY-W090151
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Silyl-ether based ROMP monomer iPrSi is a biochemical reagent that can be used in the synthesis of advanced polymer materials for biomedical applications, including drug delivery vehicles and hydrogels .
|
-
- HY-130671A
-
|
(R)-1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol sodium
|
Liposome
|
Others
|
|
L-DPPG ((R)-1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol sodium) is a phospholipid targeting biological membranes. L-DPPG interacts with lipid bilayers through hydrophobic and electrostatic interactions. L-DPPG is used in research on drug delivery systems .
|
-
- HY-42990
-
|
HSPC; Hydrogenated soybean phosphatidylcholine
|
Liposome
|
Metabolic Disease
|
|
Hydrogenated soya phosphatidylcholine (hydrogenated soybean phosphatidylcholine) is a natural product. Hydrogenated soya phosphatidylcholine can extend drug release in regard to drug loading and solubility for oral drug delivery of watersoluble drugs .
|
-
- HY-W440727
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG-Vinylsulfone (MW 2000) is a thiol reactive polyPEG via thiol-ene reaction to form a thioether bond. It can self-assemble in water and is used to prepare liposome as drug vehicle for targeted delivery into tissues.
|
-
- HY-P10741
-
-
- HY-W440690
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG-Amine (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles.
|
-
- HY-W440724
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG-Thiol (MW 3400) is an amphiphatic PEG derivative which forms micelles in water and can be used to prepare liposomes or nanoparticles for drug delivery system. The thiol moiety is reactive with maleimide to form a stable thioether bond.
|
-
- HY-W590593
-
|
|
Liposome
|
Cancer
|
|
mPEG-Cholesterol,MW 2000 is a PEG derivative which self-assembles in water to form micelle-like structure. The cholesterol tail can be used to encapsulate hydrophobic drugs while the PEG chain ehances the water solubility of the micelles.
|
-
- HY-W591913
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG-methoxy, MW 2000 is a PEG derivative which self-assembles in water to form micelle-like structure. The cholesterol tail can be used to encapsulate hydrophobic drugs while the PEG chain ehances the water solubility of the micelles.
|
-
- HY-P5533
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
CRT, an iron peptide mimic, can bind to apo-transferrin (apo-Tf). CRT can be used to modify nanoparticles, and enhances drug delivery efficiency .
|
-
- HY-122274
-
|
|
Parasite
|
Infection
|
|
MMV666693 is a translation inhibitor specific for Plasmodium falciparum. MMV666693 has low cytotoxicity in human fibroblasts (IC50>32 µM) and can be used in the development of antimalarial drugs .
|
-
- HY-144773A
-
|
HR1405–01
|
COX
|
Inflammation/Immunology
|
|
Loxoprofenol-SRS tromethamine (HR1405-01), an active metabolite of Loxoprofen, is a Safe intravenous non-steroidal anti-inflammatory drug (NSAID) with superior anti-inflammatory and analgesic activities .
|
-
- HY-W409806
-
|
|
Liposome
|
Inflammation/Immunology
|
|
Cholesterylamine is a cationic lipid. Cholesterylamine can be added to the PLGA to prepare PLGA particle having surface charge. Cholesterylamine can be used for drug delivery. Cholesterylamine can be used for autoimmune diseases and allergy research .
|
-
- HY-156516
-
|
|
ADC Cytotoxin
Topoisomerase
|
Cancer
|
|
10NH2-11F-Camptothecin is a Camptothecin (HY-16560) analogue that serves as an ADC cytotoxin for the synthesis of antibody-drug conjugates (ADCs). 10NH2-11F-Camptothecin can inhibit tumor growth and is used in cancer research .
|
-
- HY-W440706
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG-alcohol (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.
|
-
- HY-121310
-
|
|
Bacterial
|
Infection
Cancer
|
Phthalocyanine is a photosensitizer. Phthalocyanine has a light-killing effect on bacterial biofilms, effectively inactivating bacteria. Phthalocyanine can be linked to anticancer drugs to target cancer. Phthalocyanine can also be used to develop chemical sensors for studying microbial infections and tumors .
|
-
- HY-153222
-
|
|
Bacterial
|
Infection
|
|
SEQ-9 is an orally active Mycobacterium tuberculosis (Mtb) 23S bacterial ribosome inhibitor with an IC50 of approximately 170 nM for unmethylated Mtb ribosomes. SEQ-9 also potently inhibits A2296 methylated ribosomes. SEQ-9 can be used to study bacterial infection and drug resistance .
|
-
- HY-W339838
-
|
14:0 Lyso PG
|
Liposome
|
Cancer
|
|
1-Myristoyl-2-hydroxy-sn-glycero-3-PG sodium is a lysophospholipid containing myristic acid (14:0) at the sn-1 position. It has been used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
|
-
- HY-160979
-
|
DA-5047
|
Histamine Receptor
|
Others
Endocrinology
|
|
Bisfentidine is an H2 receptor antagonist, Bisfentidine can block the H2 receptor on the cells of the stomach wall, and reduce the secretion of stomach acid. Bisfentidine binds to cytochrome P-450 in liver microsomes and affects drug metabolism. Bisfentidine can be used in the study of metabolic processes of drugs, lipid peroxidation processes and peptic ulcers diseases .
|
-
- HY-130407
-
|
|
PROTAC Linkers
|
Cancer
|
|
Lipoamido-PEG3-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Lipoamido-PEG3-OH (compound TA-TEG-G2CN) can be used in the formation of a highly stable, dendronized gold nanoparticle (AuNP)-based drug delivery platform .
|
-
- HY-W009033
-
-
- HY-W440991
-
|
|
Liposome
|
Cancer
|
|
DOPE-PEG-Amine (MW 2000) is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form a triazole ring.
|
-
- HY-B2247A
-
|
poly(lactic-co-glycolic acid) (75:25)
|
Biochemical Assay Reagents
|
Others
|
|
PLGA (75:25) is a low toxicity, biocompatible and biodegradable controlled drug delivery carrier, can achieve slow release in the organism. PLGA (75:25) is a copolymer of 75% poly lactic acid (PLA) and 25% poly glycolic acid (PGA). PLGA (75:25) has been extensively studied as delivery vehicles for agents, proteins and various other macromolecules such as DNA, RNA and peptides .
|
-
- HY-145485
-
|
|
Biochemical Assay Reagents
|
Others
|
|
HS-PEG-SH (MW 3400), a linear homobifunctional PEG, is a cross-linker. HS-PEG-SH can be used for drug delivery and preparation of PEG hydrogels .
|
-
- HY-P2046
-
|
|
Opioid Receptor
|
Neurological Disease
|
|
β-Endorphin (rat) is an endogenous opioid neuropeptide and peptide hormone. β-Endorphin (rat) has analgesic activity and also contributes to food intake in satiated rats. β-Endorphin (rat) can be used in the research of neurological diseases such as analgesia and drug addiction .
|
-
- HY-145323
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
Mitochondria-Targeted Photoactivatable Proagent accumulates in the mitochondria and shows light-triggered temporally controlled cell death. Mitochondria-Targeted Photoactivatable Proagent can be used in a novel drug delivery platform that provides on-demand, real-time, organelle-specific agent release and monitoring upon photoactivation .
|
-
- HY-P10560
-
|
|
Biochemical Assay Reagents
|
Others
|
|
M918 is a cell-penetrating peptide. M918 is internalized by cells through endocytosis and can effectively penetrate a variety of cells in a non-toxic manner. M918 can be used in gene therapy and drug delivery system research .
|
-
- HY-W109224
-
|
|
ADC Linker
|
Cancer
|
|
3,3'-(Propane-2, 2-Diylbis (sulfanediyl))dipropionic acid is a ROS-sensitive cleavable linker that can be used in the synthesis of ADCs. 3,3'-(Propane-2,2-diylbis(sulfanediyl))dipropionic acid is promising for research of tumor drug delivery systems .
|
-
- HY-W440704
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG-NHS (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 5000) can be used in drug delivery research .
|
-
- HY-156517
-
|
|
ADC Cytotoxin
Topoisomerase
|
Cancer
|
|
7Ethanol-10NH2-11F-Camptothecin is a Camptothecin (HY-16560) analogue that serves as an ADC cytotoxin for the synthesis of antibody-drug conjugates (ADCs). 7Ethanol-10NH2-11F-Camptothecin can inhibit tumor growth and is used in cancer research .
|
-
- HY-163977
-
|
2,2-Diphenyl-1,3-dioxa-2-silacyclooct-5-ene
|
Biochemical Assay Reagents
|
Others
|
|
Silyl-ether based ROMP Monomer (2,2-Diphenyl-1,3-dioxa-2-silacyclooct-5-ene) is a biochemical reagent that can be used in the synthesis of advanced polymer materials for biomedical applications, including drug delivery vehicles and hydrogels .
|
-
- HY-D2762
-
|
|
Fluorescent Dye
|
Cancer
|
|
18:1 PE TopFluor AF 594 triammonium is a fluorescently labeled phospholipid probe. 18:1 PE TopFluor AF 594 triammonium can be used as a fluorescent tracer for lipid nanoparticles (LNPs). 18:1 PE TopFluor AF 594 triammonium is promising for research of drug delivery systems .
|
-
- HY-W591332
-
|
|
Liposome
|
Cancer
|
|
DMPE-mPEG, MW 2000 is a PEGylated 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE) compound with a methyl group at the other end of the PEG chain. The PEG polymer exhibits amphiphatic behavior and helps to form stable micelles in an aqueous solution. It can be used to prepare nanoparticles or liposomes for targeted drug delivery applications.
|
-
- HY-148668
-
|
SHR-A1811 Drug-linker
|
Drug-Linker Conjugates for ADC
Topoisomerase
|
Cancer
|
|
MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM) .
|
-
- HY-160597
-
|
|
ADC Cytotoxin
Topoisomerase
|
Cancer
|
|
Exatecan-amide-bicyclo[1.1.1]pentan-1-ol (Compound 79) is an exatecan (HY-13631) derivative that can be used as a payload in drug conjugates. Exatecan-amide-bicyclo[1.1.1]pentan-1-ol has significant inhibitory activity against a variety of tumor cell lines .
|
-
![Exatecan-amide-bicyclo[1.1.1]pentan-1-ol](//file.medchemexpress.com/product_pic/hy-160597.gif)
- HY-125861A
-
|
MC(Viscosity:15mPa.s)
|
Biochemical Assay Reagents
|
Others
|
|
Methyl cellulose (MC) (Viscosity:15mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:15mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .
|
-
- HY-125861H
-
|
MC(Viscosity:25mPa.s)
|
Biochemical Assay Reagents
|
Others
|
|
Methyl cellulose (MC) (Viscosity:25mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:25mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .
|
-
- HY-125861E
-
|
MC(Viscosity:4000mPa.s)
|
Biochemical Assay Reagents
|
Others
|
|
Methyl cellulose (MC) (Viscosity:4000mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:4000mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .
|
-
- HY-125861B
-
|
MC(Viscosity:400mPa.s)
|
Biochemical Assay Reagents
|
Others
|
|
Methyl cellulose (MC) (Viscosity:400mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:400mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .
|
-
- HY-125861D
-
|
MC(Viscosity:40000mPa.s)
|
Biochemical Assay Reagents
|
Others
|
|
Methyl cellulose (MC) (Viscosity:40000mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:40000mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .
|
-
- HY-125861C
-
|
MC(Viscosity:1500mPa.s)
|
Biochemical Assay Reagents
|
Others
|
|
Methyl cellulose (MC) (Viscosity:1500mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:1500mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .
|
-
- HY-125861
-
|
MC(Viscosity:100000mPa.s)
|
Biochemical Assay Reagents
|
Others
|
|
Methyl cellulose (MC) (Viscosity:100000mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:100000mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .
|
-
- HY-P10502
-
|
|
LDLR
|
Others
|
|
L57 exhibits high affinity to the low-density lipoprotein receptor-related protein 1 (LRP1) with Ki of 45 nM. L57 exhibits blood-brain barrier (BBB) permeability and plasma stability. L57 can be utilized as the carrier for CNS drug delivery .
|
-
- HY-126393
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Carboxymethyl-β-cyclodextrin, 99% is a cationic cyclodextrin used as a carrier for drugs. It has been shown to bind nonsteroidal anti-inflammatory drugs (NSAIDs) with high affinity and selectivity.
|
-
- HY-W663740
-
|
MNP; MeNP; N-Methyl-N'-nitrosopiperazine
|
Biochemical Assay Reagents
|
Others
|
|
1-Methyl-4-nitrosopiperazine (MNP; MeNP;N-Methyl-N'-nitrosopiperazine) is a potential impurity in sartans, non-steroidal anti-inflammatory drugs (NSAIDs), and thiazide diuretics .
|
-
- HY-W105639A
-
|
Calcium lactate pentahydrate, meets USP testing specifications
|
Biochemical Assay Reagents
|
Others
|
|
Calcium L-lactate pentahydrate, meets USP testing specifications (Calcium lactate pentahydrate, meets USP testing specifications) is a biochemical reagent and serves as one of the important sources of calcium. Compared to other organic calcium salts, Calcium L-lactate pentahydrate, meets USP testing specifications exhibits excellent solubility and bioavailability. Calcium L-lactate pentahydrate, meets USP testing specifications possesses remarkable moisture resistance, thermal stability, and chemical stability and can be used in medical implants and drug delivery systems .
|
-
- HY-171341
-
|
|
Biochemical Assay Reagents
|
Others
|
|
H-Pro-2-ClTrt resin is an acid-sensitive resin for solid-phase peptide synthesis. H-Pro-2-ClTrt resin binds to amino acids through an acid-labile chlorotrityl linker. H-Pro-2-ClTrt resin is promising for research of peptide drug development .
|
-
- HY-N2894
-
|
|
Parasite
|
Infection
|
|
Piperolactam A is a natural product that can be isolated from root of Piper betle. Piperolactam A exhibits promising leishmanicidal action against wild type and drug resistant strains of Leishmania donovani .
|
-
- HY-W441021
-
|
|
Liposome
|
Others
|
|
DSPE-Pyrene is a phospholipid molecule with polycyclic aromatic hydrocarbon, and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles. Pyrene is a fluorescent probe whose spectrum is sensitive to the polarity of its environment.
|
-
- HY-W043170
-
|
|
Phosphatase
|
Cancer
|
|
PRL3-CNNM4 PPI IN 1 (Compound C28d52) is an inhibitor of the PRL3-CNNM4 interaction and also inhibits PRL-mediated suppression of CNNM. PRL3-CNNM4 PPI IN 1 is capable of penetrating epithelial cell layers, exhibits metabolic stability, possesses favorable pharmacokinetic and pharmacodynamic properties, and holds potential for drug development based on this compound .
|
-
- HY-131468
-
|
AMD473; ZD0473
|
DNA/RNA Synthesis
|
Cancer
|
|
Picoplatin (AMD473) is a platinum-based antineoplastic agent. Picoplatin is specifically to circumvent thiol-mediated drug resistance by sterically hindering its reaction with glutathione (GSH) while still retaining the ability to form cytotoxic lesions with DNA .
|
-
- HY-160774
-
|
|
Drug-Linker Conjugates for ADC
Topoisomerase
|
Cancer
|
|
Val-Cit-PABC-DOX (compound 10109), an epsilon-poly-L-lysine-based drug conjugate, is an agent-linker conjugate for ADC by using a DNA topoisomerase I and topoisomerase II inhibitor, Doxorubicin (HY-15142), linked via the linker, Val-Cit-PABC .
|
-
- HY-A0273
-
|
4-Isopropylantipyrine; Isopropylphenazone
|
COX
|
Inflammation/Immunology
|
|
Propyphenazone (4-Isopropylantipyrine) is an orally active nonacidic pyrazole nonsteroidal anti-inflammatory drug (NSAID). Propyphenazone is a weak nonselective COX inhibitor. Propyphenazone has the effect of reducing pain and antipyretic activity with minimal anti-inflammatory activity .
|
-
- HY-126055A
-
|
|
Adenylate Cyclase
|
Others
|
|
Hadacidin sodium is a competitive inhibitor of adenylate synthase. Hadacidin sodium binds to the active site of adenylate synthase, competitively inhibiting L-aspartate binding. Hadacidin sodium can be used in drug design, to help develop new inhibitors or activators to regulate adenylate synthase activity, and to play a role in the study of related diseases .
|
-
- HY-126055
-
|
|
Adenylate Cyclase
|
Others
|
|
Hadacidin is a competitive inhibitor of adenylate synthase. Hadacidin binds to the active site of adenylate synthase, competitively inhibiting L-aspartate binding. Hadacidin can be used in drug design, to help develop new inhibitors or activators to regulate adenylate synthase activity, and to play a role in the study of related diseases .
|
-
- HY-115415
-
|
|
Liposome
|
Others
|
|
1,2-Distearoyl-sn-glycero-3-phosphate, sodium salt is a phospholipid commonly used as a component of liposome formulations and drug delivery systems. 1,2-Distearoyl-sn-glycero-3-phosphate, sodium salt has unique chemical properties that make it an effective tool for encapsulating drugs and delivering them to specific targets in the body. It acts as a stabilizer and emulsifier, which can improve the solubility and bioavailability of drugs.
|
-
- HY-P10216
-
|
|
Biochemical Assay Reagents
|
Neurological Disease
|
|
CAQK peptide selectively binds to injured mouse brain. CAQK peptide selectively targets demyelinating areas and it is absent from healthy tissue. The CAQK peptide target is a proteoglycan complex upregulated in brain injuries and is used for drug delivery. CAQK peptide can penetrate the blood-brain barrier .
|
-
- HY-156514
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
MC-GGFG-AM-(10NH2-11F-Camptothecin) is an antibody drug conjugates (ADC). MC-GGFG-AM-(10NH2-11F-Camptothecin) binds to the anti-TROp-2 antibody sacituzumab via a hydrolysable pH-sensitive linker and has anti-tumor activity. MC-GGFG-AM-(10NH2-11F-Camptothecin) can be used for cancer research .
|
-
- HY-116910
-
|
|
GABA Receptor
|
Neurological Disease
|
|
CPP-115 is a GABA transaminase inactivator with higher affinity and lower retinal toxicity than Vigabatrin (HY-15399). CPP-115 increases brain GABA levels by inhibiting GABA transaminase catabolism. CPP-115 can be used in the study of drug addiction and infantile spasms .
|
-
- HY-N9535A
-
|
|
Drug Metabolite
|
Metabolic Disease
|
|
(R)-tert-OMe-byakangelicin is a kind of furanocoumarin, which has inhibitory activity to liver drug metabolizing enzyme (DME) activity. (R)-tert-OMe-byakangelicin can be isolated from immature fruits of Angelica sinensis .
|
-
- HY-B1057S2
-
|
Fenazoxine-d3
|
β-catenin
|
Neurological Disease
|
|
Nefopam-d3 is a deuterium labeled Nefopam (Fenazoxine). Nefopam is a centrally-acting but non-opioid analgesic drug, and Nefopam targets β-catenin protein level in mesenchymal cells .
|
-
- HY-134129
-
|
Benzoyl CoA
|
Endogenous Metabolite
|
Others
Metabolic Disease
|
|
Benzoyl coenzyme A (Benzoyl CoA) is A derivative of Coenzyme A (CoA) in which the mercaptan group of CoA binds to the benzoyl group. Benzoyl coenzyme A is involved in the catalytic reaction as a substrate for the acyl transfer reaction. Benzoyl coenzyme A is a versatile metabolic intermediate that can be used to reveal substrate specificity of enzymes, metabolic regulation, and drug metabolism .
|
-
- HY-W440917
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-FITC, MW 5000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
|
-
- HY-W440915
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-FITC, MW 2000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
|
-
- HY-125619
-
|
|
Liposome
|
Others
|
|
1,2-dioctanoyl-sn-glycero-3-phosphocholine, is a phospholipid commonly used as a component of liposome formulations and drug delivery systems. 1,2-dioctanoyl-sn-glycero-3-phosphocholine has unique chemical properties that allow it to form stable bilayers and vesicles, allowing drug encapsulation and delivery to specific targets in the body. It acts as a stabilizer and emulsifier, which can improve the solubility and bioavailability of drugs.
|
-
- HY-147354
-
|
|
LYTACs
|
Cardiovascular Disease
|
TriGalNAc CBz is a GalNAc derivative and tri-GalNAc is an asialoglycoprotein receptor (ASGPR) ligand. TriGalNAc CBz can be used for mRNA drug delivery as well as lysosomal targeted chimerism (LYTAC) studies .
|
-
- HY-W591449
-
|
|
Liposome
|
Cancer
|
|
DOPE-PEG-Azide, MW 2000 is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .
|
-
- HY-153725
-
|
|
Liposome
|
Cancer
|
|
17:1 Lyso PC is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .
|
-
- HY-128754
-
|
|
Endogenous Metabolite
Interleukin Related
TNF Receptor
NO Synthase
|
Inflammation/Immunology
|
|
Monoolein is a biocompatible lipid molecule that can be used as a carrier for bone repair. Monoolein exhibits anti-inflammatory activity by inhibiting the immune response induced by LPS (HY-D1056). It exerts its anti-inflammatory effects by reducing the production of immune response factors such as IL-12 p40, IL-6, and TNF-α, and inhibiting the generation of NO. Monoolein can be used in drug delivery and research in the field of inflammatory diseases .
|
-
- HY-141126
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
Azido-PEG4-alpha-D-mannose is a PEG linker that combines an azide group with an alpha-D-mannose moiety. Azido-PEG4-alpha-D-mannose is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Azido-PEG4-alpha-D-mannose has the targeting property of mannose, which can accurately deliver drugs to specific cells or tissues to improve the therapeutic effect of drugs .
|
-
- HY-D2452
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-Ccisplatin is a compound of Cyanine 3 fluorescent dye CY3 (HY-D0822) combined with Cisplatin (HY-17394). Cy3-Ccisplatin can be used for drug delivery, fluorescent labeling, cell imaging and tracking .
|
-
- HY-156630
-
|
|
Liposome
|
Others
|
|
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .
|
-
- HY-156630A
-
|
|
Liposome
|
Others
|
|
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .
|
-
- HY-106823
-
-
- HY-169509
-
|
|
PARP
Necroptosis
Topoisomerase
RIP kinase
Mixed Lineage Kinase
|
Cancer
|
|
Topoisomerase I/II Inhibitor 8 (Compound Ru7) is a dual catalytic inhibitor of Topoisomerase I/II, capable of inducing DNA damage and PARP-1 activation, which subsequently leads to the activation of RIPK1, RIPK3, and MLKL, ultimately triggering necroptosis. Topoisomerase I/II Inhibitor 8 demonstrates remarkable anticancer activity by effectively targeting the nuclei of cancer cells and inducing cell death through necroptosis, showing great clinical potential in circumventing drug resistance in cancer treatment .
|
-
- HY-134129B
-
|
Benzoyl CoA sodium
|
Endogenous Metabolite
|
Others
Metabolic Disease
|
|
Benzoyl coenzyme A (sodium) is the sodium salt form of Benzoyl coenzyme A (HY-134129). Benzoyl coenzyme A (sodium) is A derivative of Coenzyme A (CoA) in which the mercaptan group of CoA binds to the benzoyl group. Benzoyl coenzyme A (sodium) is involved in the catalytic reaction as a substrate for the acyl transfer reaction. Benzoyl coenzyme A (sodium) is a versatile metabolic intermediate that can be used to reveal substrate specificity of enzymes, metabolic regulation, and drug metabolism .
|
-
- HY-144018
-
|
|
Liposome
|
Others
|
|
18:1 EPC (chloride), an egg phosphatidylcholine, is used for liposomes applied in drug delivery .
|
-
- HY-101478A
-
|
|
mGluR
Apoptosis
|
Neurological Disease
Cancer
|
|
Fenobam hydrate is a selective and orally active mGluR5 antagonist (IC50=84 nM) that can penetrate the blood-brain barrier. Fenobam hydrate shows the Kd values of 54 nM and 31 nM on rat and human recombinant mGlu5 receptors, respectively. Fenobam hydrate has anxiolytic activity, inhibits self-administration behavior in rat, and induces apoptosis in cancer cells. Fenobam hydrate can be used for research on neurological diseases, cancer and drug addiction .
|
-
- HY-134783
-
|
|
Liposome
|
Others
|
|
1,19-Bis(2-butyloctyl) 10-[[3-(dimethylamino)propyl](1-oxononyl)amino]nonadecanedioate is an excipient for vaccines. 1,19-Bis(2-butyloctyl) 10-[[3-(dimethylamino)propyl](1-oxononyl)amino]nonadecanedioate can be used for the research of the development of COVID-19 vaccines and drug delivery for gene therapy .
|
-
amino]nonadecanedioate](//file.medchemexpress.com/product_pic/hy-134783.gif)
- HY-135759
-
|
|
Bacterial
|
Infection
|
|
Cetraxate is an orally active antiulcer Drug. Cetraxate increases the blood flow of gastric mucosal. Cetraxate increases the eradication of Helicobacter pylori in smokers when in combination with Omeprazole (HY-B0113),Amoxicillin (HY-B0467A), and Clarithromycin (HY-17508) .
|
-
- HY-A0273R
-
|
4-Isopropylantipyrine (Standard); Isopropylphenazone (Standard)
|
Reference Standards
COX
|
Inflammation/Immunology
|
|
Propyphenazone (Standard) is the analytical standard of Propyphenazone. This product is intended for research and analytical applications. Propyphenazone (4-Isopropylantipyrine) is an orally active nonacidic pyrazole nonsteroidal anti-inflammatory drug (NSAID). Propyphenazone is a weak nonselective COX inhibitor. Propyphenazone has the effect of reducing pain and antipyretic activity with minimal anti-inflammatory activity .
|
-
- HY-112523A
-
|
|
Liposome
|
Others
|
|
DMTAP is a cationic lipid that can be used for delivery of DNA, RNAi and drugs .
|
-
- HY-144000D
-
-
- HY-144000K
-
-
- HY-144000C
-
-
- HY-144000E
-
-
- HY-144000J
-
-
- HY-144000H
-
-
- HY-144000B
-
-
- HY-164500
-
|
|
Apoptosis
Histone Methyltransferase
|
Cancer
|
|
MC3629 is an inhibitor of histone methyltransferase (EZH2) with anti-tumor activity. MC3629 inhibits SHH MB cancer cell proliferation and self-renewal and induces apoptosis. MC3629 can be used to study drug resistance in tumor aggressiveness .
|
-
- HY-112760
-
|
DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium
|
Liposome
|
Others
|
|
18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .
|
-
- HY-W440893
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-OH, MW 5000 is a linear phospholipid PEG polymer. The lipid tails allow encapsulation of hdyrophobic therapeutics while the PEG chain maintains its hydrophilicity. The polymer can be used for drug nanocarrier, such as liposomal anti cancer drug or mRNA/DNA vaccine. Reagent grade, for research use only.
|
-
- HY-P10539
-
|
|
Bacterial
|
Infection
|
|
Hp1404 is a novel cationic antimicrobial peptide. Hp1404 has specific inhibitory activity against Gram-positive bacteria, including Staphylococcus aureus (MRSA) resistant to Laburnetin (HY-N7382). Hp1404 has antimicrobial activity, low toxicity, and is not prone to drug resistance, and can be used in the research of antimicrobial agents .
|
-
- HY-168943B
-
-
- HY-W1123940A
-
-
- HY-W1123940C
-
-
- HY-W1123940
-
-
- HY-W1123940D
-
-
- HY-168943
-
-
- HY-W1123940B
-
-
- HY-144021
-
|
|
Liposome
|
Others
|
|
14:0 EPC chloride is an acyl cationic lipid that can be used for liposomes applied in drug delivery .
|
-
- HY-W016420
-
|
MK-0955 sodium
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Fosfomycin (MK-0955) sodium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin sodium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .
|
-
- HY-B1075A
-
|
MK-0955
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .
|
-
- HY-P10649A
-
|
|
Fluorescent Dye
|
Cancer
|
|
CPP12 TFA is a small, amphiphilic, cyclic cell-penetrating peptide (CPP) in salt form. CPP12 TFA binds directly to plasma membrane phospholipids, enters mammalian cells via endocytosis, and is then efficiently released from endosomes. CPP12 TFA can be used for intracellular delivery of drugs and chemical probes .
|
-
- HY-144022
-
|
|
Liposome
|
Others
|
|
16:0 DAP is a cationic lipids that can be used for drug delivery, gene transfection and vaccine delivery .
|
-
- HY-168943C
-
-
- HY-144007
-
|
|
Liposome
|
Others
|
|
Chol-PEG is a nonionic surfactant vesicles and can be used for a blood-persistent drug delivery system .
|
-
- HY-144025
-
|
|
Liposome
|
Others
|
|
DOBAQ, a cationic lipid, is a pH-sensitive lipid. DOBAQ can be used for liposomes applied in drug delivery .
|
-
- HY-W441003
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-IA, MW 2000 is a thiol reactive phospholipid polyPEG. The iodoacetyll group is reactive with thiol to produce a thioether linkage. The polymer can self-assemble in water to form lipid bilayer and can be used to encapsulate drugs in targeted delivery application, such as liposomal doxorubicin as an anti cancer drug or mRNA vaccine. Reagent grade, for research use only.
|
-
- HY-B1075
-
|
MK-0955 calcium
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Fosfomycin (MK-0955) calcium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin calcium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .
|
-
- HY-B0609
-
|
MK-0955 tromethamine
|
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Fosfomycin (MK-0955) tromethamine is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin tromethamine shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .
|
-
- HY-112624B
-
|
Dextran 70; Dextran D70; Dextran T70(MW 64000-76000)
|
Bacterial
|
Others
|
|
Dextran 70,000 is a high molecular weight polysaccharide formed by glucose linked by α-(1→6) glycosidic bonds. Dextran 70,000 can expand blood volume through colloidal osmotic pressure effect and inhibit cell adhesion and platelet aggregation through steric hindrance. At the same time, Dextran 70,000 can be used as a drug carrier to achieve targeted delivery through endocytosis. Dextran 70,000 is biologically inert and has low immunogenicity. It can be used for clinical blood volume expansion, anti-thrombotic research, and evaluation of vascular permeability in in vitro experiments. It can also be combined with fluorescent dyes for cell tracking and drug delivery research. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance.
|
-
- HY-112755
-
|
|
Liposome
|
Others
|
|
DODMA is a cationic lipid that can be used to prepare lipid nanoparticles. DODMA can be used for drug delivery .
|
-
- HY-144023
-
|
|
Liposome
|
Others
|
|
16:0-18:1 EPC chloride is a cationic lipid, which can be used for liposomes applied in drug delivery .
|
-
- HY-150644
-
|
|
Aldose Reductase
|
Cancer
|
|
S07-2010 is a potent pan-AKR1C (aldo-keto reductase family 1 member C) inhibitor, with IC50 values of 0.19, 0.36, 0.47, and 0.73 μM for AKR1C3, AKR1C4, AKR1C1 and AKR1C2, respectively. S07-2010 induces apoptosis in A549/DDP cells. S07-2010 strengthens the cytotoxicity of chemotherapeutic agents in drug-resistant cells. S07-2010 significantly inhibits the proliferation of drug-resistant cells .
|
-
- HY-142992
-
-
- HY-142977
-
|
|
Liposome
Drug Intermediate
|
Others
|
|
6-Oxohexyl 2-hexyldecanoate, 80% (ELSD) is an intermediate in the synthesis of ALC-0315. ALC-0315 is an ionizable amino lipid. ALC-0315 is a key component of LNP delivery vehicles. 6-Oxohexyl 2-hexyldecanoate, 80% (ELSD) is an effective delivery vehicle of mRNA .
|
-
- HY-143695
-
|
|
Liposome
|
Others
|
|
16:0 TAP is a lipid product. 16:0 TAP can be used for the preparation of giant unilamellar vesicles to deliver agents .
|
-
- HY-W1048508C
-
-
- HY-W1048509C
-
-
- HY-173171
-
-
- HY-W1048828H
-
-
- HY-W1048508B
-
-
- HY-W1048509B
-
-
- HY-W1048828J
-
-
- HY-101103
-
|
(2-Hydroxypropyl)-β-cyclodextrin
|
Biochemical Assay Reagents
|
Cancer
|
|
HP-β-CD ((2-Hydroxypropyl)-β-cyclodextrin) is a widely used drug delivery vehicle to improve the stability and bioavailability.
|
-
- HY-138622
-
|
|
Liposome
|
Others
|
|
24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery .
|
-
- HY-W1048509A
-
-
- HY-W1048508A
-
-
- HY-W1048509D
-
-
- HY-W1048508D
-
-
- HY-CP002
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Bovine Serum Albumin (BSA) is a 583 amino acid protein consisting of three homologous full alpha structural domains. BSA is a spherical protein essential for the transport of molecules such as fatty acids, drugs and hormones from the blood. It is used in many biochemical applications as a drug carrier for biologically active compounds. For long-term storage, recombinant protein solution should be diluted further with 0.1% BSA .
|
-
- HY-165427
-
|
|
Liposome
|
Cancer
|
|
Lipid 11 (Compound Lipid 1) is a cationic lipid for nucleic acid delivery. Lipid 11 forms lipid nanoparticles (LNPs) through electrostatic binding with nucleic acids (such as ceDNA). Lipid 11 forms complexes with negatively charged nucleic acids via cationic amine groups, which can be endocytosed by cells to release nucleic acids for activity. Lipid 11 is promising for research of gene therapy drug delivery systems .
|
-
- HY-Y0873O
-
|
Polyethylene glycol 35000
|
Biochemical Assay Reagents
|
Others
|
|
PEG35000 is a polyethylene glycol with a molecular weight of 35,000 that can be used as a carrier material and modifier in drug delivery systems .
|
-
- HY-N2427R
-
|
|
Reference Standards
Others
|
Others
|
|
Adamantane (Standard) is the analytical standard of Adamantane. This product is intended for research and analytical applications. Adamantane, a polycyclic cage molecule with high symmetry and remarkable properties. Adamantane can be incorporated into a lipophilic part of the lipid bilayer that constitutes membranes and as an anchor in the lipid bilayer of liposomes. Adamantane can be used in research of surface recognition and drug delivery .
|
-
- HY-P5033
-
|
|
Bacterial
|
Cancer
|
Cyclo(Gly-His) is a liposome-encapsulated cyclic dipeptide with antimicrobial and anticancer activity. Cyclo(Gly-His) has cytotoxicity for HeLa and MCF-7 cell with IC50 values of 1.699 mM and 0.358 mM, respectively. Cyclo(Gly-His) can be used for the research of drug delivery systems .
|
-
- HY-169336
-
|
|
PARP
PSMA
|
Cancer
|
|
CQ-16 is an orally active small molecule drug conjugate (SMDC) targeting prostate-specific membrane antigen (PSMA). CQ-16 exhibits highly selective antiproliferative activity between PSMA-positive and PSMA-negative prostate cells. In addition, CQ-16 also has PARP inhibitory activity (IC50=1 nM). (Pink: PSMA Ligand (HY-139840); Black: Linker (HY-W037980); Blue: PARP Inhibitor (HY-10162))
|
-
- HY-W1111591
-
|
mPEG-Hydroxy (MW 350); Polyethylene glycol monomethyl ether (MW 350)
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-OH (MW 350) (mPEG-Hydroxy (MW 350)) is a derivative of polyethylene glycol (PEG) that can be used for drug delivery .
|
-
- HY-140696H
-
|
mPEG-Hydroxy (MW 750); Polyethylene glycol monomethyl ether (MW 750)
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-OH (MW 750) (mPEG-Hydroxy (MW 750)) is a derivative of polyethylene glycol (PEG) that can be used for drug delivery .
|
-
- HY-W1048855D
-
-
- HY-W1048512C
-
-
- HY-W1048855C
-
-
- HY-148601
-
|
DSPG
|
Liposome
|
Others
|
|
1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol is an anionic phospholipid, can be used for drug delivery and the synthesis of liposomes.
|
-
- HY-W1048855B
-
-
- HY-W1048855A
-
-
- HY-144027
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dolichol (13~21) is a lipid carrier containing isoprene units. Dolichol (13~21) can be used for liposomes applied in drug delivery .
|
-
- HY-140696B
-
|
mPEG-Hydroxy (MW 550); Polyethylene glycol monomethyl ether (MW 550)
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-OH (MW 550) (mPEG-Hydroxy (MW 550)) is a derivative of polyethylene glycol (PEG) that can be used for drug delivery .
|
-
- HY-W1048512A
-
-
- HY-W440886
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Biotin, MW 3400 is a phospholipid PEG for biotinylation. The amphiphilic property of the DSPE-PEG is useful for precision drug delivery and cancer therapy.
|
-
- HY-W1048512D
-
-
- HY-W1048512B
-
-
- HY-W440903
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.
|
-
- HY-W440926
-
|
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.
|
-
- HY-144020
-
|
|
Liposome
|
Others
|
|
14:0 DAP (1,2-dimyristoyl-3-dimethylammonium-propane ) is a cationic lipid that can be used for drug delivery .
|
-
- HY-Y0873A1
-
|
Polyethylene glycol 100000
|
Biochemical Assay Reagents
|
Others
|
|
PEG100000 (Polyethylene glycol 100000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-Y1219C
-
-
- HY-Y0873A9
-
|
Polyethylene glycol 2000000
|
Biochemical Assay Reagents
|
Others
|
|
PEG2000000 (Polyethylene glycol 2000000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-Y0873A2
-
|
Polyethylene glycol 600000
|
Biochemical Assay Reagents
|
Others
|
|
PEG600000 (Polyethylene glycol 600000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-Y0873A5
-
|
Polyethylene glycol 200000
|
Biochemical Assay Reagents
|
Others
|
|
PEG200000 (Polyethylene glycol 200000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-W1048851A
-
-
- HY-Y1219H
-
-
- HY-W1048851D
-
-
- HY-Y0873A7
-
|
Polyethylene glycol 900000
|
Biochemical Assay Reagents
|
Others
|
|
PEG900000 (Polyethylene glycol 900000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-Y1219I
-
-
- HY-Y0873A4
-
|
Polyethylene glycol 4000000
|
Biochemical Assay Reagents
|
Others
|
|
PEG4000000 (Polyethylene glycol 4000000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-W1048851B
-
|
4-Arm-PEG-Maleimide (MW 10000)
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG-MAL (MW 10000) can be used for site-specific protein and peptide modification and can be used for drug delivery .
|
-
- HY-Y0873A6
-
|
Polyethylene glycol 400000
|
Biochemical Assay Reagents
|
Others
|
|
PEG400000 (Polyethylene glycol 400000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-Y0873B1
-
|
Polyethylene glycol 8000000
|
Biochemical Assay Reagents
|
Others
|
|
PEG8000000 (Polyethylene glycol 8000000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-Y1219D
-
-
- HY-Y0873A3
-
|
Polyethylene glycol 1000000
|
Biochemical Assay Reagents
|
Others
|
|
PEG1000000 (Polyethylene glycol 1000000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-172357
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Poly (3-hydroxybutyric acid-co-3-hydroxyvaleric acid) is a biodegradable polymer that can be used to construct nanoparticles for drug delivery .
|
-
- HY-Y0873A8
-
|
Polyethylene glycol 5000000
|
Biochemical Assay Reagents
|
Others
|
|
PEG5000000 (Polyethylene glycol 5000000) is a polymer compound with good biocompatibility and biodegradability, and is widely used in drug controlled release systems and bioadhesive materials .
|
-
- HY-Y1219E
-
-
- HY-W1048851C
-
-
- HY-115340
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Decanoic acid sodium, also known as Decanoic acid sodium, is a salt of the fatty acid capric acid. It is easily soluble in water and has a slightly soapy smell. Decanoic acid sodium acts as a penetration enhancer, which means it increases the absorption and bioavailability of drugs across biological membranes, including the intestinal epithelium and the blood-brain barrier. This property makes it useful in pharmaceutical formulations to improve drug delivery and effectiveness. Furthermore, Decanoic acid sodium has potential applications in food preservatives and cosmetics due to its antibacterial properties.
|
-
- HY-P99230
-
|
|
Integrin
CD22
|
Cancer
|
|
Pinatuzumab is a humanized monoclonal antibody targeting cell-surface antigen CD22. Pinatuzumab can be used to synthesize antibody-drug conjugate (ADC) such as Pinatuzumab vedotin (HY-141602). Pinatuzumab can be studied in research on cancer such as non-Hodgkin lymphoma. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .
|
-
- HY-W440916
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-FITC, MW 3400 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
|
-
- HY-162220
-
|
|
Estrogen Receptor/ERR
17β-HSD
|
Metabolic Disease
|
|
HSD17B13-IN-94 (Compound 12) is an effective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for Estradiol (HY-B0141). HSD17B13-IN-94 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD, NASH, or drug-induced liver injury (DILI) .
|
-
- HY-W001132
-
Indole
1 Publications Verification
|
Endogenous Metabolite
|
Infection
|
|
Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule .
|
-
- HY-149156
-
|
|
Liposome
|
Cancer
|
|
Lipid C24 is a cationic ionizable lipid that can be used for synthesizing lipid nanoparticles. Lipid C24 can be used in the study of drug delivery .
|
-
- HY-139480B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Poly(ethylene glycol) dithiol (Mn 1500) is a thiol-modified PEG that can be used to synthesize dithiol-terminated amphiphilic diblock copolymers for drug delivery .
|
-
- HY-139480A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Poly(ethylene glycol) dithiol (Mn 1000) is a thiol-modified PEG that can be used to synthesize dithiol-terminated amphiphilic diblock copolymers for drug delivery .
|
-
- HY-B1075R
-
|
MK-0955 calcium (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Fosfomycin (calcium) (Standard) is the analytical standard of Fosfomycin (calcium). This product is intended for research and analytical applications. Fosfomycin (MK-0955) calcium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin calcium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .
|
-
- HY-172711A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG3400-R6H4 can be used for drug delivery .
|
-
- HY-172711
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG2000-R6H4 can be used for drug delivery .
|
-
- HY-172712
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3000-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG3000-R6H4 can be used for drug delivery .
|
-
- HY-172710
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-R6H4 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (R6H4). R6H4 can be used for pH responsive anticancer drug delivery purposes. DSPE-PEG1000-R6H4 can be used for drug delivery .
|
-
- HY-W440885
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-Ald, MW 5000 is a phospholipid PEG polymer which can self-assemble spontaneously in water with their hydrophilic heads oriented toward the water (micelles). The polymer can be used to prepare liposome as a drug nanocarrier for administration of nutrients and therapeutic drugs, such as lipid nanoparticles in mRNA or DNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
-
- HY-169320
-
|
|
Cytochrome P450
|
Cancer
|
|
SJPYT-328 is a PXR agonsit. PXR plays a major role in drug metabolism and drug-drug interactions .
|
-
- HY-112307A
-
|
|
Liposome
|
Others
|
|
(Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) is an anionic phospholipid, can be used for drug delivery and the synthesis of liposomes .
|
-
- HY-144008
-
|
|
Liposome
|
Others
|
|
C8 PEG-Ceramide is a lipid product. C8 PEG-Ceramide can synthesize lipid bilayer carrier and can be used for drug delivery .
|
-
- HY-143210
-
|
|
Liposome
|
Metabolic Disease
|
|
Transfectam is a cationic lipid able to interact with DNA to form complexes that mediate efficient gene transfer into various eukaryotic cells .
|
-
- HY-143692
-
-
- HY-N5159
-
|
|
iGluR
|
Neurological Disease
|
|
Ampullosporin A is a peptaibol-type polypeptide that can be isolated from the fungus Sepedonium ampullosporum HKI-0053, exhibiting neuroleptic-like activity. Ampullosporin A can inhibit hyperactivity induced by NMDA receptor antagonist MK-801 (HY-15084B) and ameliorate social behavior abnormalities caused by subchronic drug treatment. Ampullosporin A alters the activity of glutamate receptors without affecting dopamine D1 and D2 receptors .
|
-
- HY-W1049129D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-mal (MW 40000) is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG-mal (MW 40000) can be used for drug delivery .
|
-
- HY-W1048552
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-mal (MW 1000) is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG-mal (MW 1000) can be used for drug delivery .
|
-
- HY-W1049129C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-mal (MW 20000) is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG-mal (MW 20000) can be used for drug delivery .
|
-
- HY-W1049129B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-mal (MW 10000) is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG-mal (MW 10000) can be used for drug delivery .
|
-
- HY-150241
-
|
|
Liposome
|
Others
|
|
DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery .
|
-
- HY-145885
-
|
|
Toll-like Receptor (TLR)
|
Infection
Inflammation/Immunology
Cancer
|
|
TLR7/8 agonist 6 (Compound 4) is the potent agonist of TLR7/8 with IC50s of 0.18 and 5.34 μM, respectively. TLR7/8 agonist 6 is an imidazoquinoline derivative compound. Toll-like receptors (TLRs) 7 and 8 are key targets in the development of immunomodulatory drugs for researching infectious disease, cancer, and autoimmune disorders .
|
-
- HY-145886
-
|
|
Toll-like Receptor (TLR)
|
Infection
Inflammation/Immunology
Cancer
|
|
TLR7/8 Antagonist 1 (Compound 16c) is the potent antagonist of TLR7/8 with IC50s of 3.91 and 2.19 μM, respectively. TLR7/8 Antagonist 1 is an imidazoquinoline derivative compound. Toll-like receptors (TLRs) 7 and 8 are key targets in the development of immunomodulatory drugs for researching infectious disease, cancer, and autoimmune disorders .
|
-
- HY-144008A
-
|
|
Liposome
|
Others
|
|
C8 PEG5000 Ceramide is a lipid product. C8 PEG5000 Ceramide can synthesize lipid bilayer carrier and can be used for drug delivery .
|
-
- HY-W020780C
-
|
mPEG-Maleimide (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-Mal (MW 3400) is a PEG derivative used for thiol pegylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
-
- HY-172382B
-
|
PGCL, 65:35
|
Biochemical Assay Reagents
|
Others
|
|
Poly(D,L-lactide-co-glycolide), 65:35 (PGCL, 65:35) is a copolymer formed by the ring-opening polymerization of lactide and glycolide, which can be used for drug delivery .
|
-
- HY-W441015A
-
|
|
Liposome
|
Others
|
|
DSPE-m-PEG-NHS (MW 3400) is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
|
-
- HY-W020780A
-
|
mPEG-Maleimide (MW 350)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-Mal (MW 350) is a PEG derivative used for thiol PEGylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
-
- HY-172382A
-
|
PGCL,75:25
|
Biochemical Assay Reagents
|
Others
|
|
Poly(D,L-lactide-co-glycolide), 75:25 (PGCL, 75:25) is a copolymer formed by the ring-opening polymerization of lactide and glycolide, which can be used for drug delivery .
|
-
- HY-W020780B
-
|
mPEG-Maleimide (MW 750)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-Mal (MW 750) is a PEG derivative used for thiol pegylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
-
- HY-172382
-
|
PGCL, 50:50
|
Biochemical Assay Reagents
|
Others
|
|
Poly(D,L-lactide-co-glycolide), 50:50 (PGCL, 50:50) is a copolymer formed by the ring-opening polymerization of lactide and glycolide, which can be used for drug delivery .
|
-
- HY-164657
-
|
PAMAM
|
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
Polyamidoamine (PAMAM) (20% in methanol) is a new type of drug carrier that has drug encapsulation capabilities internally and biocompatibility on the surface, and can be used as a drug delivery system.
|
-
- HY-172274
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-APRPG is a PEG compound which composed of DSPE and a APRPG peptide. DSPE-PEG1000-APRPG can be used for drug delivery .
|
-
- HY-172274B
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-APRPG is a PEG compound which composed of DSPE and a APRPG peptide. DSPE-PEG5000-APRPG can be used for drug delivery .
|
-
- HY-172274A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-APRPG is a PEG compound which composed of DSPE and a APRPG peptide. DSPE-PEG2000-APRPG can be used for drug delivery .
|
-
- HY-109541
-
|
DMPC; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine; Dimyristoyl phosphatidylcholine
|
Liposome
|
Cancer
|
|
Colfosceril miristate (DMPC) is a synthetic phospholipid. Colfosceril miristate has antiproliferative effects on various tumors. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery .
|
-
- HY-172168A
-
|
|
Fluorescent Dye
|
Others
|
|
Orange Fluorescent PLGA nanoparticles, 200nm a nanoparticle made from the polymer PLGA and labeled with an orange fluorescent dye. Orange Fluorescent PLGA nanoparticles, 200nm can be used for drug delivery and for tracing .
|
-
- HY-172174
-
|
|
Fluorescent Dye
|
Others
|
|
Red Fluorescent PLGA nanoparticles, 100nm is a nanoparticle made from the polymer PLGA and labeled with a red fluorescent dye. Red Fluorescent PLGA nanoparticles, 100nm can be used for drug delivery and for tracing .
|
-
- HY-172168B
-
|
|
Fluorescent Dye
|
Others
|
|
Orange Fluorescent PLGA nanoparticles, 500nm a nanoparticle made from the polymer PLGA and labeled with an orange fluorescent dye. Orange Fluorescent PLGA nanoparticles, 500nm can be used for drug delivery and for tracing .
|
-
- HY-172168
-
|
|
Fluorescent Dye
|
Others
|
|
Orange Fluorescent PLGA nanoparticles, 100nm a nanoparticle made from the polymer PLGA and labeled with an orange fluorescent dye. Orange Fluorescent PLGA nanoparticles, 100nm can be used for drug delivery and for tracing .
|
-
- HY-172174B
-
|
|
Fluorescent Dye
|
Others
|
|
Red Fluorescent PLGA nanoparticles, 500nm is a nanoparticle made from the polymer PLGA and labeled with a red fluorescent dye. Red Fluorescent PLGA nanoparticles, 500nm can be used for drug delivery and for tracing .
|
-
- HY-172174A
-
|
|
Fluorescent Dye
|
Others
|
|
Red Fluorescent PLGA nanoparticles, 200nm is a nanoparticle made from the polymer PLGA and labeled with a red fluorescent dye. Red Fluorescent PLGA nanoparticles, 200nm can be used for drug delivery and for tracing .
|
-
- HY-142654
-
|
|
Liposome
|
Others
|
|
ATX-002 is an ionizable cationic lipid for RNA drug delivery. The calculated pKa (c-pKa) and measured pKa values for ATX-002 are 8.68 and 6.03, respectively .
|
-
- HY-104086
-
|
CB7; Carrier CB7
|
Biochemical Assay Reagents
|
Others
|
|
Cucurbit[7]uril is a cyclic organic molecule consisting of seven glycoluril units linked by methylene bridges. It has a rigid barrel-like structure with two identical inlets at both ends to selectively encapsulate guest molecules of appropriate size, shape, and polarity. Cucurbit[7]uril is known for its high binding affinity for a variety of organic and inorganic guests, including drugs, amino acids, peptides, and metal ions. This property makes them promising candidates for various applications in areas such as drug delivery, catalysis, and sensing.
|
-
![Cucurbit[7]uril](//file.medchemexpress.com/product_pic/hy-104086.gif)
- HY-172278C
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG3400-CGKRK can be used for drug delivery .
|
-
- HY-W763557B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Poly(ethylene glycol) methacrylate (MW 500) is a monomethacrylate functionalized PEG, which is used to prepare composite materials, such as Poly(ethylene glycol) methacrylate-chitosan, and can be used as an ocular drug delivery carrier .
|
-
- HY-W763557A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Poly(ethylene glycol) methacrylate (MW 360) is a monomethacrylate functionalized PEG, which is used to prepare composite materials, such as Poly(ethylene glycol) methacrylate-chitosan, and can be used as an ocular drug delivery carrier .
|
-
- HY-140741
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG-OH, MW 2000 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Additionally, DSPE-PEG-OH, MW 2000 can also be used for drug delivery .
|
-
- HY-172680
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG1000-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG1000-VIP can be used for drug delivery .
|
-
- HY-W008034
-
|
|
Amino Acid Derivatives
|
Cancer
|
|
Fmoc-L-Trp(Boc)-OH is an amino acid derivative with a protective group, which has the ability to self-assemble and form nanoparticles. Fmoc-L-Trp(Boc)-OH can be used in the study of anticancer drug delivery .
|
-
- HY-W441009A
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Maleimide (MW 3400) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 3400) ammonium can be used in drug delivery research .
|
-
- HY-172278A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG2000-CGKRK can be used for drug delivery .
|
-
- HY-172278B
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG5000-CGKRK can be used for drug delivery .
|
-
- HY-172278
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-CGKRK is a PEG compound which composed of DSPE and a cell-penetrating peptide (CGKRK). DSPE-PEG1000-CGKRK can be used for drug delivery .
|
-
- HY-W441009C
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Maleimide (MW 4000) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 4000) ammonium can be used in drug delivery research .
|
-
- HY-172681
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG2000-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG2000-VIP can be used for drug delivery .
|
-
- HY-W441009B
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Maleimide (MW 1000) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 1000) ammonium can be used in drug delivery research .
|
-
- HY-W441009H
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Maleimide (MW 40000) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 40000) ammonium can be used in drug delivery research .
|
-
- HY-172682
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG5000-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG5000-VIP can be used for drug delivery .
|
-
- HY-172681A
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG3400-VIP is a PEG compound which composed of DSPE and a vasoactive intestinal peptide (VIP). DSPE-PEG3400-VIP can be used for drug delivery .
|
-
- HY-W441009E
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Maleimide (MW 20000) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 20000) ammonium can be used in drug delivery research .
|
-
- HY-B2247
-
|
poly(lactic-co-glycolic acid) (50:50)
|
Biochemical Assay Reagents
|
Others
|
|
PLGA (50:50) (poly(lactic-co-glycolic acid) (50:50)) is a copolymer of poly lactic acid (PLA) and poly glycolic acid (PGA) which can be used to fabricate devices for drug delivery and tissue engineering applications.
|
-
- HY-W441009D
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Maleimide (MW 10000) ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide (MW 10000) ammonium can be used in drug delivery research .
|
-
- HY-W001132R
-
|
|
Reference Standards
Endogenous Metabolite
|
Infection
|
|
Indole (Standard) is the analytical standard of Indole. This product is intended for research and analytical applications. Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule .
|
-
- HY-W1048511
-
|
2-Arm PEG-Amine (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
|
2-Arm PEG-NH2 (MW 5000) (2-Arm PEG-Amine (MW 5000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
-
- HY-W1048511A
-
|
2-Arm PEG-Amine (MW 20000)
|
Biochemical Assay Reagents
|
Others
|
|
2-Arm PEG-NH2 (MW 20000) (2-Arm PEG-Amine (MW 20000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
-
- HY-W1048511C
-
|
2-Arm PEG-Amine (MW 10000)
|
Biochemical Assay Reagents
|
Others
|
|
2-Arm PEG-NH2 (MW 10000) (2-Arm PEG-Amine (MW 10000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
-
- HY-W1048511B
-
|
2-Arm PEG-Amine (MW 40000)
|
Biochemical Assay Reagents
|
Others
|
|
2-Arm PEG-NH2 (MW 40000) (2-Arm PEG-Amine (MW 40000)) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
-
- HY-W1049085C
-
|
mPEG-Succinimidyl Succinate ester (MW 20000)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-SS (MW 20000) (mPEG-Succinimidyl Succinate ester (MW 20000)) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG-SS (MW 20000) can be used for drug delivery .
|
-
- HY-W1049085B
-
|
mPEG-Succinimidyl Succinate ester (MW 10000)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-SS (MW 10000) (mPEG-Succinimidyl Succinate ester (MW 10000)) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG-SS (MW 10000) can be used for drug delivery .
|
-
- HY-144015
-
|
|
Liposome
|
Others
|
|
14:1 EPC trifluoromethanesulfonate is ethyl-phosphatidylcholine (EPC) with monounsaturated 14:1 chains. 14:1 EPC trifluoromethanesulfonate shows transfection activity. 14:1 EPC trifluoromethanesulfonate can be used for drug delivery .
|
-
- HY-W1049085E
-
|
mPEG-Succinimidyl Succinate ester (MW 2000)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-SS (MW 2000) (mPEG-Succinimidyl Succinate ester (MW 2000)) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG-SS (MW 2000) can be used for drug delivery .
|
-
- HY-W440892
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-OH, MW 3400 is an amphiphilic polydisperse PEG which can spontaneously self-assemble in aqueous solution. The polymer can be used to prepare liposoome for targeted drug delivery. Reagent grade, for research use only.
|
-
- HY-W1049085D
-
|
mPEG-Succinimidyl Succinate ester (MW 40000)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-SS (MW 40000) (mPEG-Succinimidyl Succinate ester (MW 40000)) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG-SS (MW 40000) can be used for drug delivery .
|
-
- HY-W1049085
-
|
mPEG-Succinimidyl Succinate ester (MW 1000)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-SS (MW 1000) (mPEG-Succinimidyl Succinate ester (MW 1000)) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG-SS (MW 1000) can be used for drug delivery .
|
-
- HY-W1049085H
-
|
mPEG-Succinimidyl Succinate ester (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-SS (MW 3400) (mPEG-Succinimidyl Succinate ester (MW 3400)) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG-SS (MW 3400) can be used for drug delivery .
|
-
- HY-W1049085A
-
|
mPEG-Succinimidyl Succinate ester (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-SS (MW 5000) (mPEG-Succinimidyl Succinate ester (MW 5000)) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG-SS (MW 5000) can be used for drug delivery .
|
-
- HY-N0235
-
|
(S)-(+)-Bakuchiol
|
Carboxylesterase (CES)
p38 MAPK
Autophagy
UGT
|
Infection
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2) , with IC50s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory , antibacterial , antitumor therapies, as well as drug metabolism regulation.
|
-
- HY-W1048605
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG-Mal (MW 5000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG-Mal (MW 5000) can be used for drug delivery .
|
-
- HY-W1048574J
-
|
OHC-PEG-carboxyl (MW 40000)
|
Biochemical Assay Reagents
|
Others
|
|
OHC-PEG-COOH (MW 40000) (OHC-PEG-carboxyl (MW 40000)) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG-COOH (MW 40000) can be used for drug delivery .
|
-
- HY-W1048510B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Arm PEG-Mal (MW 20000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 2-Arm PEG-Mal (MW 20000) can be used for drug delivery .
|
-
- HY-W1048574H
-
|
OHC-PEG-carboxyl (MW 1000)
|
Biochemical Assay Reagents
|
Others
|
|
OHC-PEG-COOH (MW 1000) (OHC-PEG-carboxyl (MW 1000)) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG-COOH (MW 1000) can be used for drug delivery .
|
-
- HY-W1048510A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Arm PEG-Mal (MW 10000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 2-Arm PEG-Mal (MW 10000) can be used for drug delivery .
|
-
- HY-W1048605C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG-Mal (MW 40000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG-Mal (MW 40000) can be used for drug delivery .
|
-
- HY-W1048574I
-
|
OHC-PEG-carboxyl (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
|
OHC-PEG-COOH (MW 3400) (OHC-PEG-carboxyl (MW 3400)) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG-COOH (MW 3400) can be used for drug delivery .
|
-
- HY-W1048574A
-
|
OHC-PEG-carboxyl (MW 2000)
|
Biochemical Assay Reagents
|
Others
|
|
OHC-PEG-COOH (MW 2000) (OHC-PEG-carboxyl (MW 2000)) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG-COOH (MW 2000) can be used for drug delivery .
|
-
- HY-W1048510C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Arm PEG-Mal (MW 40000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 2-Arm PEG-Mal (MW 40000) can be used for drug delivery .
|
-
- HY-W1048574E
-
|
OHC-PEG-carboxyl (MW 20000)
|
Biochemical Assay Reagents
|
Others
|
|
OHC-PEG-COOH (MW 20000) (OHC-PEG-carboxyl (MW 20000)) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG-COOH (MW 20000) can be used for drug delivery .
|
-
- HY-W1048510D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Arm PEG-Mal (MW 5000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 2-Arm PEG-Mal (MW 5000) can be used for drug delivery .
|
-
- HY-W1048605B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG-Mal (MW 10000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG-Mal (MW 10000) can be used for drug delivery .
|
-
- HY-W1048605A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG-Mal (MW 20000) is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG-Mal (MW 20000) can be used for drug delivery .
|
-
- HY-W1048574D
-
|
OHC-PEG-carboxyl (MW 10000)
|
Biochemical Assay Reagents
|
Others
|
|
OHC-PEG-COOH (MW 10000) (OHC-PEG-carboxyl (MW 10000)) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG-COOH (MW 10000) can be used for drug delivery .
|
-
- HY-155901
-
|
Maleimide-NH-PEG-amine TFA (MW 2000)
|
Biochemical Assay Reagents
|
Others
|
|
Mal-NH-PEG-NH2 (TFA) (MW 2000) is a PEG derivative that may be used for thiol PEGylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
-
- HY-W1048574C
-
|
OHC-PEG-carboxyl (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
|
OHC-PEG-COOH (MW 5000) (OHC-PEG-carboxyl (MW 5000)) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG-COOH (MW 5000) can be used for drug delivery .
|
-
- HY-164296
-
|
|
ADC Linker
|
Cancer
|
|
SMP-96745 is a dual-drug targeting linker-drug conjugate and can be used for study of cancer .
|
-
- HY-109541S2
-
|
DMPC-d9; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d9
|
Isotope-Labeled Compounds
|
Cancer
|
|
Colfosceril miristate-d9 (DMPC-d9) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery .
|
-
- HY-109541S1
-
|
DMPC-d4; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d4
|
Isotope-Labeled Compounds
|
Cancer
|
|
Colfosceril miristate-d4 (DMPC-d4) is deuterium labeled Colfosceril miristate. Colfosceril miristate is a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery .
|
-
- HY-172279A
-
|
|
Liposome
|
Infection
|
|
DSPE-PEG2000-TAT is a PEG compound which composed of DSPE and a cell-penetrating peptide (TAT) (HY-P0281). DSPE-PEG2000-TAT can be used for drug delivery .
|
-
- HY-109541S3
-
|
DMPC-d13; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d13
|
Isotope-Labeled Compounds
|
Others
|
|
Colfosceril miristate-d13 (DMPC-d13) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery .
|
-
- HY-109541S
-
|
DMPC-d58; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d58
|
Isotope-Labeled Compounds
|
Cancer
|
|
Colfosceril miristate-d58 (DMPC-d58) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery .
|
-
- HY-172279B
-
|
|
Liposome
|
Infection
|
|
DSPE-PEG3000-TAT is a PEG compound which composed of DSPE and a cell-penetrating peptide (TAT) (HY-P0281). DSPE-PEG3000-TAT can be used for drug delivery .
|
-
- HY-143209B
-
|
|
Liposome
|
Others
|
|
DSPE-PEG3400 is a phospholipids-polymer conjugate that can be used in drug delivery applications. DSPE-PEG3400 is a material for the formulation of nanocarriers for achieving prolonged blood circulation time, improved stability and enhanced encapsulation efficiency .
|
-
- HY-172279
-
|
|
Liposome
|
Infection
|
|
DSPE-PEG1000-TAT is a PEG compound which composed of DSPE and a cell-penetrating peptide (TAT) (HY-P0281). DSPE-PEG1000-TAT can be used for drug delivery .
|
-
- HY-W440897
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-SH, MW 3400 is a maleimide reactive PEG lipid. The amphiphilic polymer forms lipid bilayer in water and can be used to prepare liposomes for drug nanocarriers to deliver mRNA, DNA or siRNA. Reagent grade, for research use only.
|
-
- HY-109541S4
-
|
DMPC-d63; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d63
|
Isotope-Labeled Compounds
|
Cancer
|
|
Colfosceril miristate-d63 (DMPC-d63) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery .
|
-
- HY-172279C
-
|
|
Liposome
|
Infection
|
|
DSPE-PEG3400-TAT is a PEG compound which composed of DSPE and a cell-penetrating peptide (TAT) (HY-P0281). DSPE-PEG3400-TAT can be used for drug delivery .
|
-
- HY-W440895
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-SH (MW 1000) is an amphiphilic poly-PEG that can form lipid bilayers in water. This amphiphilic polymer can form lipid bilayers in aqueous solution and can be used to embed active molecules for drug delivery systems such as mRNA vaccines.
|
-
- HY-172276A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG2000-R8 can be used for drug delivery .
|
-
- HY-172276
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG1000-R8 can be used for drug delivery .
|
-
- HY-164035
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG-DBCO (MW 2000) is a PEG lipid with a DOPE and a DBCO as functional groups. DOPE can be used as a helper lipid in gene transfection. PEG is used in drug delivery system. DBCO can be used for click chemistry .
|
-
- HY-172276C
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG3400-R8 can be used for drug delivery .
|
-
- HY-W440900
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-SPDP, MW 3400 is an amphiphilic polyPEG which forms lipid bilayer in water. It can be used to encapsualte therapeutic agents, such as hydrophilic nutrierns (protein/peptide, mRNA/DNA/siRNA) or hdyrophobic drugs ( Reagent grade, for research use only.
|
-
- HY-172276B
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG5000-R8 can be used for drug delivery .
|
-
- HY-132972
-
|
|
TrxR
|
Cancer
|
|
TrxR-IN-2, a potential thioredoxin reductase (TrxR) inhibitor, represents a promising candidate drug for the chemoresearch of drug-resistant hepatocellular carcinoma.
|
-
- HY-172483
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3000-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG3000-TAASGVRSMH can be used for drug delivery .
|
-
- HY-W440896
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.
|
-
- HY-172482A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG3400-TAASGVRSMH can be used for drug delivery .
|
-
- HY-W1049091B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-Alkyne (MW 10000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
|
-
- HY-W1049091D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-Alkyne (MW 40000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
|
-
- HY-W1049091A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-Alkyne (MW 5000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
|
-
- HY-144016
-
|
|
Liposome
|
Others
|
|
16:0 EPC chloride, a P-O-ethyl derivative, is a saturated cationic lipid. 16:0 EPC chloride can serve as a DNA and RNA transfecting agent. 16:0 EPC chloride can be used as a co-adjuvant for preparing vaccines and promote drug delivery .
|
-
- HY-172481
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG1000-TAASGVRSMH can be used for drug delivery .
|
-
- HY-W1049105
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-Alkyne (MW 2000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
|
-
- HY-W1049091
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-Alkyne (MW 1000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
|
-
- HY-172482
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG2000-TAASGVRSMH can be used for drug delivery .
|
-
- HY-W1049091C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-Alkyne (MW 20000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
|
-
- HY-W1049091E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-Alkyne (MW 3400) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
|
-
- HY-148049
-
|
|
Liposome
|
Others
|
|
TT3 is an ionizable lipid-like material and a lipid nanoparticle (LLNs)-based mRNA delivery vector. TT3 exhibits liver and spleen specificity and excellent delivery efficiency .
|
-
- HY-W440928
-
|
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
DSPE-PEG-DBCO, MW 5000 is a phospholipid polyPEG which can self-assemble in water to form lipid bilayer. The polymer can be used to prepare liposomes as drug carrier to deliver nutrients/therpeutic agents, such as mRNA or DNA. Reagent grade, for research use only.
|
-
- HY-172277B
-
|
|
Liposome
|
Neurological Disease
|
|
DSPE-PEG5000-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG5000-R9 can be used for drug delivery .
|
-
- HY-172687
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG2000-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). CSTSMLKAC is capable of mediating selective homing of phage to ischemic heart tissue. DSPE-PEG2000-CSTSMLKAC can be used for drug delivery .
|
-
- HY-172727
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG5000-EB1 can be used for drug delivery .
|
-
- HY-172687A
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG3400-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). CSTSMLKAC is capable of mediating selective homing of phage to ischemic heart tissue. DSPE-PEG3400-CSTSMLKAC can be used for drug delivery .
|
-
- HY-172686
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG1000-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). CSTSMLKAC is capable of mediating selective homing of phage to ischemic heart tissue. DSPE-PEG1000-CSTSMLKAC can be used for drug delivery .
|
-
- HY-172725
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG1000-EB1 can be used for drug delivery .
|
-
- HY-172726
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG2000-EB1 can be used for drug delivery .
|
-
- HY-172277A
-
|
|
Liposome
|
Neurological Disease
|
|
DSPE-PEG2000-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG2000-R9 can be used for drug delivery .
|
-
- HY-172726A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG3400-EB1 can be used for drug delivery .
|
-
- HY-172688
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG5000-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). CSTSMLKAC is capable of mediating selective homing of phage to ischemic heart tissue. DSPE-PEG5000-CSTSMLKAC can be used for drug delivery .
|
-
- HY-172277C
-
|
|
Liposome
|
Neurological Disease
|
|
DSPE-PEG3400-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG3400-R9 can be used for drug delivery .
|
-
- HY-172277
-
|
|
Liposome
|
Neurological Disease
|
|
DSPE-PEG1000-R9 is a PEG compound which composed of DSPE and a poly-arginine-9 peptide (R9). DSPE-PEG1000-R9 can be used for drug delivery .
|
-
- HY-172270D
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
|
-
- HY-172270C
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
|
-
- HY-172270
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
|
-
- HY-172270A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
|
-
- HY-N0235R
-
|
(S)-(+)-Bakuchiol (Standard)
|
Carboxylesterase (CES)
Reference Standards
p38 MAPK
Autophagy
UGT
|
Infection
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Bakuchiol (Standard) is the analytical standard of Bakuchiol. This product is intended for research and analytical applications. Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2) , with IC50s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory , antibacterial , antitumor therapies, as well as drug metabolism regulation.
|
-
- HY-W440906
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-Vinylsulfone, MW 3400 is a thiol reactive PEG lipid. The polymer can self-assemble spontaneously in aqueous solution to form lipid bilayer and be used to prepare nanoparticles/liposomes for drug delivery, for example mRNA vaccine or DNA vaccine. Reagent grade, for research use only.
|
-
- HY-W440921
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Rhodamine, MW 5000 is a phospholipid polyPEG with red fluorescent. The polymer can form lipid bilayer and be used to prepare nanoparticles or liposomes for targeted drug delivery. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
|
-
- HY-W440920
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Rhodamine, MW 3400 is a phospholipid polyPEG with red fluorescent. The polymer can form lipid bilayer and be used to prepare nanoparticles or liposomes for targeted drug delivery. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
|
-
- HY-172442
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Hyaluronidase is an enzyme that can break down hyaluronic acid. Hyaluronidase can increase the absorption of drugs into tissues and reduce tissue damage in cases of drug extravasation .
|
-
- HY-172405
-
|
|
Drug Derivative
|
Others
|
|
Captisol is a chemically modified β-cyclodextrin derivative. Captisol has the primary activity of enhancing the water solubility of poorly soluble drugs. The main regulatory mechanism of captisol is to encapsulate drug molecules through the hydrophobic cavity, and the hydrophilic outer surface improves dispersibility. Captisol can be used to improve the bioavailability and stability of drugs. Captisol can also be used in the development of drug delivery systems, such as the preparation of inclusion complexes or physical mixtures .
|
-
- HY-W1048527A
-
|
8-Arm PEG-Thiol (MW 20000)
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG-SH (MW 20000) (8-Arm PEG-Thiol (MW 20000)) is a multi-arm PEG derivative with thiol groups at each end of the eight arms. 8-Arm PEG-SH (MW 20000) can be used for drug delivery .
|
-
- HY-172473
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG2000-NGR can be used for drug delivery .
|
-
- HY-172708A
-
|
|
Liposome
|
Neurological Disease
|
|
DSPE-PEG3400-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG3400-PP1 can be used for drug delivery .
|
-
- HY-172504
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG5000-KAA can be used for drug delivery .
|
-
- HY-172473A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG34000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG3400-NGR can be used for drug delivery .
|
-
- HY-172503A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG3400-KAA can be used for drug delivery .
|
-
- HY-153137
-
|
304O13
|
Liposome
|
Cancer
|
|
Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate is a biodegradable lipid prepared by the conjugate addition of alkylamines to acrylates. Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate can be used in various drug delivery systems to deliver polynucleotides, siRNA for example .
|
-
- HY-W440891
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-OH, MW 1000 is a hydroxyl terminated phospholipid PEG polymer. The hydrophobic tails allow for the encapsulation and congregation of other hydrophobic drugs. The polymer can be used to prepare liposomes or lipid nanoparticles. Hydroxyl terminal can further derivatize the compound. Reagent grade, for research use only.
|
-
- HY-172685
-
|
|
Liposome
|
Others
|
|
DSPE-PEG5000-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG5000-GRGDS can be used for drug delivery .
|
-
- HY-W1048527
-
|
8-Arm PEG-Thiol (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG-SH (MW 5000) (8-Arm PEG-Thiol (MW 5000)) is a multi-arm PEG derivative with thiol groups at each end of the eight arms. 8-Arm PEG-SH (MW 5000) can be used for drug delivery .
|
-
- HY-172474
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG5000-NGR can be used for drug delivery .
|
-
- HY-172502
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG1000-KAA can be used for drug delivery .
|
-
- HY-172684A
-
|
|
Liposome
|
Others
|
|
DSPE-PEG3400-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG3400-GRGDS can be used for drug delivery .
|
-
- HY-172709
-
|
|
Liposome
|
Neurological Disease
|
|
DSPE-PEG5000-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG5000-PP1 can be used for drug delivery .
|
-
- HY-172472
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG1000-NGR can be used for drug delivery .
|
-
- HY-172684
-
|
|
Liposome
|
Others
|
|
DSPE-PEG2000-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG2000-GRGDS can be used for drug delivery .
|
-
- HY-W1048527B
-
|
8-Arm PEG-Thiol (MW 40000)
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG-SH (MW 40000) (8-Arm PEG-Thiol (MW 40000)) is a multi-arm PEG derivative with thiol groups at each end of the eight arms. 8-Arm PEG-SH (MW040000) can be used for drug delivery .
|
-
- HY-172503
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG2000-KAA can be used for drug delivery .
|
-
- HY-172708
-
|
|
Liposome
|
Neurological Disease
|
|
DSPE-PEG2000-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG2000-PP1 can be used for drug delivery .
|
-
- HY-172683
-
|
|
Liposome
|
Others
|
|
DSPE-PEG1000-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG1000-GRGDS can be used for drug delivery .
|
-
- HY-W1048527C
-
|
8-Arm PEG-Thiol (MW 10000)
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG-SH (MW 10000) (8-Arm PEG-Thiol (MW 10000)) is a multi-arm PEG derivative with thiol groups at each end of the eight arms. 8-Arm PEG-SH (MW 10000) can be used for drug delivery .
|
-
- HY-172707
-
|
|
Liposome
|
Neurological Disease
|
|
DSPE-PEG1000-PP1 is a PEG compound which composed of DSPE and a PP1 peptide. PP1 peptide targets the inflammatory atherosclerotic plaque. DSPE-PEG1000-PP1 can be used for drug delivery .
|
-
- HY-B0317F
-
|
|
Calcium Channel
|
Infection
|
|
Amlodipine hydrochloride is a biologically active drug used to lower blood pressure and prevent chest pain. Amlodipine hydrochloride has shown synergistic effects with antimicrobial drugs in in vitro studies, especially against carbene peptide-resistant Acinetobacter baumannii. Amlodipine hydrochloride can be used in combination with other antibiotics to enhance the inhibitory effect against resistant bacteria. The use of amlodipine hydrochloride helps reduce the dosage requirements of the drug, reduce toxic effects, and delay the emergence of drug resistance .
|
-
- HY-W1048918B
-
|
mPEG-COOH (MW 10000)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-CM (MW 10000) (mPEG-COOH (MW 10000)) has a reactive carboxyl group (-COOH) attached to the terminal site of the structure, which can form a stable amide bond with the amino group or an ester bond with the hydroxyl group. mPEG-CM (MW 10000) can be used for drug delivery .
|
-
- HY-W250721
-
|
CBM 980
|
Biochemical Assay Reagents
|
Others
|
|
Carbomer 980 (CBM 980) is an acrylic acid polymer, which can be used as a thickening agent. Carbomer 980 provides a stable gel matrix, exhibits good heat, light and microbial contamination resistance. Carbomer 980 facilitates the drug release and local application, which can be used in the pharmaceutical industry .
|
-
- HY-W1048918C
-
|
mPEG-COOH (MW 20000)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-CM (MW 20000) (mPEG-COOH (MW 20000)) has a reactive carboxyl group (-COOH) attached to the terminal site of the structure, which can form a stable amide bond with the amino group or an ester bond with the hydroxyl group. mPEG-CM (MW 20000) can be used for drug delivery .
|
-
- HY-W1048558A
-
|
mPEG-COOH (MW 2000)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-CM (MW 2000) (mPEG-COOH (MW 2000)) has a reactive carboxyl group (-COOH) attached to the terminal site of the structure, which can form a stable amide bond with the amino group or an ester bond with the hydroxyl group. mPEG-CM (MW 2000) can be used for drug delivery .
|
-
- HY-W1048918
-
|
mPEG-COOH (MW 1000)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-CM (MW 1000) (mPEG-COOH (MW 1000)) has a reactive carboxyl group (-COOH) attached to the terminal site of the structure, which can form a stable amide bond with the amino group or an ester bond with the hydroxyl group. mPEG-CM (MW 1000) can be used for drug delivery .
|
-
- HY-W1048918A
-
|
mPEG-COOH (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-CM (MW 5000) (mPEG-COOH (MW 5000)) has a reactive carboxyl group (-COOH) attached to the terminal site of the structure, which can form a stable amide bond with the amino group or an ester bond with the hydroxyl group. mPEG-CM (MW 5000) can be used for drug delivery .
|
-
- HY-144009
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG-Folate, MW 3350 is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .
|
-
- HY-W1048918D
-
|
mPEG-COOH (MW 40000)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-CM (MW 40000) (mPEG-COOH (MW 40000)) has a reactive carboxyl group (-COOH) attached to the terminal site of the structure, which can form a stable amide bond with the amino group or an ester bond with the hydroxyl group. mPEG-CM (MW 40000) can be used for drug delivery .
|
-
- HY-W440899
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-SPDP, MW 1000 is a thiol reactive PEG lipid. The polymer is amphiphilic and spontaneously forms lipid bilayer in water. It can be used to encapsulate nutrients or therapeutics for targeted drug delivery, for example mRNA or DNA vaccine, liposomal doxorubicin for anti tumor. Reagent grade, for research use only.
|
-
- HY-W1048918E
-
|
mPEG-COOH (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-CM (MW 3400) (mPEG-COOH (MW 3400)) has a reactive carboxyl group (-COOH) attached to the terminal site of the structure, which can form a stable amide bond with the amino group or an ester bond with the hydroxyl group. mPEG-CM (MW 3400) can be used for drug delivery .
|
-
- HY-160985
-
|
|
Parasite
|
Others
|
|
Lemidosul is an anti-trypanosomiasis compound that can be further optimized for its performance as an anti-trypanosomiasis drug by means of a computer-aided drug design (CADD) approach .
|
-
- HY-124317
-
|
|
Fluorescent Dye
|
Others
|
|
PF-06649283 is a drug with potential intracellular activity. The effects of PF-06649283 may be affected by factors such as cellular metabolism, protein-protein interactions, post-translational modifications, and asymmetric intracellular localization. The potency of PF-06649283 at the cellular level may show different activity compared to the recombinant enzyme, and this difference needs to be considered in the drug discovery process. Increased intracellular potency of PF-06649283 may be critical for the development of this drug as a probe or drug .
|
-
- HY-W440888
-
|
DSPE-PEG(2000) Folate
|
Liposome
|
Others
|
|
DSPE-PEG-Folate, MW 2000 is a PEG derivative containing folic acid. DSPE-PEG-Folate, MW 2000 has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate, MW 2000 form micelles/lipid bilayer and can be used to targeted drug delivery system research.
|
-
- HY-172497
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG2000-CREKA can be used for drug delivery .
|
-
- HY-172701
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG1000-NYZL1 can be used for drug delivery .
|
-
- HY-172696
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG2000-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG2000-WYRGRL can be used for drug delivery .
|
-
- HY-172496
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG1000-CREKA can be used for drug delivery .
|
-
- HY-172696A
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG3400-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG3400-WYRGRL can be used for drug delivery .
|
-
- HY-172702A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG3400-NYZL1 can be used for drug delivery .
|
-
- HY-172498
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG5000-CREKA can be used for drug delivery .
|
-
- HY-172695
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG1000-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG1000-WYRGRL can be used for drug delivery .
|
-
- HY-172497A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-CREKA is a PEG compound which composed of DSPE and a fibrin-targeting peptide (CREKA). CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG3400-CREKA can be used for drug delivery .
|
-
- HY-172697
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG5000-WYRGRL is a PEG compound which composed of DSPE and a cartilage-targeting peptide (WYRGRL). WYRGRL is a collagen II-targeting peptide that can bind to collagen II α1. DSPE-PEG5000-WYRGRL can be used for drug delivery .
|
-
- HY-172702
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG2000-NYZL1 can be used for drug delivery .
|
-
- HY-W440898
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-SH, MW 5000 is a polyPEG attached DSPE molecule. The lipid tails allow formation of lipid bilayer in water and can be used to solubilize hydrophobic drugs while the hydrophilic core can encapsulate therapeutic agents, such as nuclein acid (mRNA/DNA), protein or peptide. Reagent grade, for research use only.
|
-
- HY-172703
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG5000-NYZL1 can be used for drug delivery .
|
-
- HY-W440919
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Rhodamine, MW 2000 is a dye functionalized phospholipid. The amphiphilic polymer can form lipid bilayer in water and be used to encapsulate therapeutic agents, such as liposomal anticancer drug or mRNA vaccine. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
|
-
- HY-133825
-
|
IKF-916
|
Oct3/4
OAT
|
Infection
|
|
Cyazofamid exerts its bactericidal effect by impairing ATP production. Cyazofamid inhibits organic cation transporter 3 (OCT3) and OAT1, with IC50 values of 1.54 and 17.3 μM, respectively .
|
-
- HY-N9248
-
|
|
Others
|
Others
|
|
6-Hydroxywogonin (compound 26) is a flavonoid compound .
|
-
- HY-B0994
-
|
Cyanoacetic hydrazide; 2-Cyanoacetohydrazide
|
Bacterial
|
Infection
|
|
Cyanoacetohydrazide is an anti-TB drug.
|
-
- HY-116787
-
|
5-OHTBZ
|
Drug Metabolite
|
Others
|
|
5-Hydroxythiabendazole (5-OHTBZ) is a biomarker of Thiabendazole (HY-B0263) exposure .
|
-
- HY-116787R
-
|
5-OHTBZ (Standard)
|
Drug Metabolite
Reference Standards
|
Others
|
|
5-Hydroxythiabendazole (Standard) is the analytical standard of 5-Hydroxythiabendazole. This product is intended for research and analytical applications. 5-Hydroxythiabendazole (5-OHTBZ) is a biomarker of Thiabendazole (HY-B0263) exposure .
|
-
- HY-15870A
-
|
|
AP-1
|
Inflammation/Immunology
Cancer
|
|
(6E)-SR 11302 is a E-isomer of SR 11302. SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor. SR 11302 is a retinoid that specifically inhibits AP-1 activity without activating the transcription of retinoic acid response element (RARE) .
|
-
- HY-141411B
-
|
(R)-MRI-1867
|
Drug Isomer
Cannabinoid Receptor
NO Synthase
|
Others
|
|
(R)-Zevaquenabant ((R)-MRI-1867) is the enantiomer of Zevaquenabant (HY-141411A). Zevaquenabant ((S)-MRI-1867) is a peripherally restricted, orally bioavailable dual cannabinoid CB1 receptor and inducible NOS antagonist. Zevaquenabant ameliorates obesity-induced chronic kidney disease (CKD) .
|
-
- HY-144008B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
C8 PEG750 Ceramide is a lipid product. C8 PEG750 Ceramide synthesizes a lipid bilayer carrier for the selective delivery of various diagnostic and therapeutic agents to acidic diseased cells .
|
-
- HY-Y0238
-
|
Bromodimethylacetyl bromide; α-Bromoisobutyryl bromide; 2-Bromoisobutylyl bromide; 2-Bromoisobutyryl bromide
|
Biochemical Assay Reagents
|
Others
|
|
2-Bromoisobutyryl bromide (Bromodimethylacetyl bromide; α-Bromoisobutyryl bromide; 2-Bromoisobutylyl bromide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-B0803S1
-
|
Benflumetol-d9
|
Isotope-Labeled Compounds
Parasite
Autophagy
|
Infection
|
|
Lumefantrine-d9 is the deuterium labeled Lumefantrine. Lumefantrine is an antimalarial drug, used in combination with Artemether. The artemether-lumefantrine (AL) as the first- and second-line anti-malarial drugs.
|
-
- HY-172275B
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG5000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG5000-pPB can be used for drug delivery .
|
-
- HY-172468
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-CTT2 is a PEG compound which composed of DSPE and a gelatinase inhibitor (CTT2 (CTTHWGFTLC)). CTT2 (CTTHWGFTLC) has the ability to specifically target tumors. DSPE-PEG5000-CTT2 can be used for drug delivery .
|
-
- HY-172470A
-
|
|
Liposome
EGFR
|
Cancer
|
|
DSPE-PEG3400-GE11 is a PEG compound which composed of DSPE and an EGFR targeting peptide (GE11). GE11 can be used for EGFR overexpressed cancer cells. DSPE-PEG3400-GE11 can be used for drug delivery .
|
-
- HY-172466
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-CTT2 is a PEG compound which composed of DSPE and a gelatinase inhibitor (CTT2 (CTTHWGFTLC)). CTT2 (CTTHWGFTLC) has the ability to specifically target tumors. DSPE-PEG1000-CTT2 can be used for drug delivery .
|
-
- HY-172275A
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG2000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG2000-pPB can be used for drug delivery .
|
-
- HY-172484
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG1000-LTLRWVGLMS can be used for drug delivery .
|
-
- HY-172485A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG3400-LTLRWVGLMS can be used for drug delivery .
|
-
- HY-172467
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-CTT2 is a PEG compound which composed of DSPE and a gelatinase inhibitor (CTT2 (CTTHWGFTLC)). CTT2 (CTTHWGFTLC) has the ability to specifically target tumors. DSPE-PEG2000-CTT2 can be used for drug delivery .
|
-
- HY-172470
-
|
|
Liposome
EGFR
|
Cancer
|
|
DSPE-PEG2000-GE11 is a PEG compound which composed of DSPE and an EGFR targeting peptide (GE11). GE11 can be used for EGFR overexpressed cancer cells. DSPE-PEG2000-GE11 can be used for drug delivery .
|
-
- HY-172486
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG5000-LTLRWVGLMS can be used for drug delivery .
|
-
- HY-172275
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG1000-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG1000-pPB can be used for drug delivery .
|
-
- HY-172469
-
|
|
Liposome
EGFR
|
Cancer
|
|
DSPE-PEG1000-GE11 is a PEG compound which composed of DSPE and an EGFR targeting peptide (GE11). GE11 can be used for EGFR overexpressed cancer cells. DSPE-PEG1000-GE11 can be used for drug delivery .
|
-
- HY-172275C
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG3400-pPB is a PEG compound which composed of DSPE and a cyclic oligopeptide (pPB). pPB has a strong binding affinity with PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG3400-pPB can be used for drug delivery .
|
-
- HY-172485
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG2000-LTLRWVGLMS can be used for drug delivery .
|
-
- HY-163549
-
-
- HY-128951
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
AMCC-DM1 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker AMCC to make antibody drug conjugate. AMCC is a noncleavable linker .
|
-
- HY-172724
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG5000-T7 can be used for drug delivery .
|
-
- HY-W441013
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-NHS, MW 1000 is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG-NHS, MW 1000 is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG-NHS, MW 1000 can be used in the study of drug delivery .
|
-
- HY-172723A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG3400-T7 can be used for drug delivery .
|
-
- HY-155882
-
|
mPEG-NH2 (MW 750)
|
Biochemical Assay Reagents
|
Cancer
|
|
mPEG-amine (MW 750) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-155880
-
|
mPEG-NH2 (MW 350)
|
Biochemical Assay Reagents
|
Cancer
|
|
mPEG-amine (MW 350) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-W441012
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-NHS, MW 600 is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG-NHS, MW 600 is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG-NHS, MW 600 can be used in the study of drug delivery .
|
-
- HY-172723
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG2000-T7 can be used for drug delivery .
|
-
- HY-W441014
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-NHS, MW 2000 is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG-NHS, MW 2000 is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG-NHS, MW 2000 can be used in the study of drug delivery .
|
-
- HY-W013466
-
|
Sebacic acid dimethyl ester
|
Biochemical Assay Reagents
|
Others
|
|
Dimethyl decanedioate belongs to the class of diesters and consists of a sebacic acid backbone (also known as sebacic acid) esterified with two methyl groups. This compound has a fruity smell and is commonly used as a flavor and fragrance ingredient in a variety of products, including perfumes, soaps and cosmetics. It can also be used as a plasticizer in the production of polymers and as a neutralizer in the synthesis of certain drugs.
|
-
- HY-W440890
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG-Folate, MW 5000 is a PEG derivative containing folic acid. DSPE-PEG-Folate, MW 5000 has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate, MW 5000 form micelles/lipid bilayer and can be used to targeted drug delivery system research .
|
-
- HY-W440936
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG-Rhodamine, MW 5000 is a fatty acid containing PEG polymer which can self assemble in an aqueous solution to form micelles. The polymer can be used to prepare nanoparticles for drug encapsulation. The red dye rhodamine can be easily traced by fluorescence microscopy. Rhodamine has maximum absorption at 570 nm and emission around 595 nm.
|
-
- HY-155883
-
|
mPEG-NH2 (MW 3400)
|
Biochemical Assay Reagents
|
Cancer
|
|
mPEG-amine (MW 3400) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-W440935
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG-Rhodamine, MW 3400 is a fatty acid containing PEG polymer which can self assemble in an aqueous solution to form micelles. The polymer can be used to prepare nanoparticles for drug encapsulation. The red dye rhodamine can be easily traced by fluorescence microscopy. Rhodamine has maximum absorption at 570 nm and emission around 595 nm.
|
-
- HY-155881
-
|
mPEG-NH2 (MW 550)
|
Biochemical Assay Reagents
|
Cancer
|
|
mPEG-amine (MW 550) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-172722
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG1000-T7 can be used for drug delivery .
|
-
- HY-154644
-
|
|
Biochemical Assay Reagents
Dopamine Receptor
|
Cancer
|
|
Soya Lecithin is a phospholipid mixture that can be used as a drug delivery vehicle and is a pharmaceutical excipient. Soya Lecithin can form a lipid bilayer structure through self-assembly, and its binding properties are amphiphilic (hydrophilic head and hydrophobic tail), encapsulating hydrophobic drugs. Soya Lecithin forms stable nanoliposomes or microemulsions, improves the solubility and cellular uptake efficiency of poorly soluble drugs (such as Curcumin (HY-N0005)), and exerts activities such as enhancing drug delivery and regulating cell proliferation .
|
-
- HY-164720
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-OH (MW 4000) is a hydroxy-terminated phospholipid PEG polymer. The hydrophobic tails that allows the encapsulation and aggregation of other hydrophobic drugs, and the hydroxy-terminated can be further reacted. DSPE-PEG-OH (MW 4000) can prepare liposomes or lipid nanoparticles, which can be used in drug delivery and promoting drug absorption research .
|
-
- HY-164723
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-OH (MW 10000) is a hydroxy-terminated phospholipid PEG polymer. The hydrophobic tails that allows the encapsulation and aggregation of other hydrophobic drugs, and the hydroxy-terminated can be further reacted. DSPE-PEG-OH (MW 10000) can prepare liposomes or lipid nanoparticles, which can be used in drug delivery and promoting drug absorption research .
|
-
- HY-164721
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-OH (MW 6000) is a hydroxy-terminated phospholipid PEG polymer. The hydrophobic tails that allows the encapsulation and aggregation of other hydrophobic drugs, and the hydroxy-terminated can be further reacted. DSPE-PEG-OH (MW 6000) can prepare liposomes or lipid nanoparticles, which can be used in drug delivery and promoting drug absorption research .
|
-
- HY-164722
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-OH (MW 8000) is a hydroxy-terminated phospholipid PEG polymer. The hydrophobic tails that allows the encapsulation and aggregation of other hydrophobic drugs, and the hydroxy-terminated can be further reacted. DSPE-PEG-OH (MW 8000) can prepare liposomes or lipid nanoparticles, which can be used in drug delivery and promoting drug absorption research .
|
-
- HY-172280B
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG5000-Octreotide can be used for drug delivery .
|
-
- HY-W440953
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Stearic acid-PEG-CH2CO2H, MW 1000 is an amphiphatic PEG polymer which forms micelles in an aqueous solution for drug-loaded nanoparticles. The terminal carboxyl can react with amine via condensation reaction in the presence of HATU/EDC activator. Reagent grade, for research use only.
|
-
- HY-172280A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG21000-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG2000-Octreotide can be used for drug delivery .
|
-
- HY-172280
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG1000-Octreotide can be used for drug delivery .
|
-
- HY-172699A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG3400-ANG can be used for drug delivery .
|
-
- HY-155884
-
|
mPEG-NH2 (MW 4000)
|
Biochemical Assay Reagents
|
Cancer
|
|
mPEG-amine (MW 4000) can be used to synthesize folate-conjugated polymer micelles for encapsulating anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-W440905
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-Vinylsulfone, MW 2000 is a phospholipid PEG which can self-assemble to form lipid bilayer in water. The polymer can be used to encapsulate therapeutics, such as nucleic acid (mRNA/DNA) or protein, in drug delivery system. The vinyl sulfone is reactive with thiol molecule via thiol-ene reaction for bioconjugation. Reagent grade, for research use only.
|
-
- HY-172281
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG1000-CCK8 is a PEG compound which composed of DSPE and a Cholecystokinin-8 (CCK8). Cholecystokinin-8 has the activity of peptide regulating gallbladder contraction and digestive system function. DSPE-PEG1000-CCK8 can be used for drug delivery .
|
-
- HY-172280C
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG3400-Octreotide can be used for drug delivery .
|
-
- HY-172281B
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG5000-CCK8 is a PEG compound which composed of DSPE and a Cholecystokinin-8 (CCK8). Cholecystokinin-8 has the activity of peptide regulating gallbladder contraction and digestive system function. DSPE-PEG5000-CCK8 can be used for drug delivery .
|
-
- HY-172698
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG1000-ANG can be used for drug delivery .
|
-
- HY-172699
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG2000-ANG can be used for drug delivery .
|
-
- HY-172700
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG5000-ANG can be used for drug delivery .
|
-
- HY-W250721C
-
|
CBM 941
|
Biochemical Assay Reagents
|
Others
|
|
Carbomer 941 (CBM 941) is an acrylic acid polymer, which can be used as a thickening agent. Carbomer 941 which forms a high viscosity gel, provides a stable gel matrix, and exhibits good heat, light and microbial contamination resistance. Carbomer 941 facilitates the drug release and local application, which can be used in the pharmaceutical industry .
|
-
- HY-172281A
-
|
|
Liposome
|
Cardiovascular Disease
|
|
DSPE-PEG2000-CCK8 is a PEG compound which composed of DSPE and a Cholecystokinin-8 (CCK8). Cholecystokinin-8 has the activity of peptide regulating gallbladder contraction and digestive system function. DSPE-PEG2000-CCK8 can be used for drug delivery .
|
-
- HY-W250721B
-
|
CBM 934
|
Biochemical Assay Reagents
|
Others
|
|
Carbomer 934 (CBM 934) is an acrylic acid polymer, which can be used as a thickening agent. Carbomer 934 which forms a high viscosity gel, provides a stable gel matrix, and exhibits good heat, light and microbial contamination resistance. Carbomer 934 facilitates the drug release and local application, which can be used in the pharmaceutical industry .
|
-
- HY-W009247
-
|
N-Demethylolanzapine; LY170055
|
Endogenous Metabolite
|
Neurological Disease
|
|
N-Desmethylolanzapine is an antipsychotic drug.
The formation of N-Desmethylolanzapine correlates with the level and activity
of human liver flavin-containing monooxygenase (FMO3). N-Desmethylolanzapine
can be used in the study of antipsychotic drugs .
|
-
- HY-B0921
-
-
- HY-B1407
-
|
N4-Phthalylsulfathiazole
|
Bacterial
Antibiotic
|
Others
|
|
Phthalylsulfathiazole is a kind of sulfonamides used as an antibacterial drug.
|
-
- HY-100146
-
-
- HY-B0416
-
-
- HY-17554
-
|
(R)-(+)-Oxiracetam; (R)-ISF2522
|
Others
|
Neurological Disease
|
|
(R)-Oxiracetam is the (R)-enantiomer of the nootropic drug oxiracetam.
|
-
- HY-149762
-
|
|
Bacterial
|
Infection
|
|
IMBI (compound 32) is an antibacterial agent that inhibits quorum sensing (QS) against drug-resistant pathogens. IMBI inhibits biofilm formation of Salmonella marcescens and restores or increases its susceptibility to antimicrobial drugs .
|
-
- HY-160683
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
MC-Gly-Gly-Phe-Gly-NH-CH2-O-amide-Eribulin (Compound 7) can be used as a linker-drug intermediate for the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-145399
-
|
SG 3932; AZ-0133
|
Drug-Linker Conjugates for ADC
Topoisomerase
|
Cancer
|
|
AZ14170133 (SG 3932) is a Drug-Linker Conjugates for ADC, which comprises a topoisomerase inhibitor and a linker for ligand unit connecting. AZ14170133 can be used to synthesis antibody-drug conjugate (ADC) .
|
-
- HY-W440907
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-Vinylsulfone, MW 5000 is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine. Reagent grade, for research use only.
|
-
- HY-172464
-
|
|
Liposome
Integrin
|
Cancer
|
|
DSPE-PEG2000-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD). cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG2000-cRGD can be used for drug delivery .
|
-
- HY-W440939
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG-FITC, MW 3400 is a PEG lipid which forms micelles in water and can be used for drug delivery applications. The FITC fluorescent can be easily traced by miscroscopy. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
|
-
- HY-W115607
-
|
Poly(ethylene glycol)-bis-amine (MW 8000)
|
Biochemical Assay Reagents
|
Cancer
|
|
PEG-bis-amine (MW 8000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-W440940
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG-FITC, MW 5000 is a PEG lipid which forms micelles in water and can be used for drug delivery applications. The FITC fluorescent can be easily traced by miscroscopy. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
|
-
- HY-W127444
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N,N-Dimethyldodecanamide is an organic compound belonging to amides. It consists of a dodecyl chain attached to a nitrogen atom and two methyl groups, forming a white crystalline solid with a faint waxy odour. N,N-Dimethyldodecanamide has several applications in industrial settings, notably as a solvent, lubricant and surfactant. In addition, it can also be used as an intermediate in the synthesis of various chemicals and drugs.
|
-
- HY-112768
-
|
|
Liposome
|
Others
|
|
PEG2000-DMPE can be used to synthsis a LNP. PEG2000-DMPE enhances the entrapment efficiency depending on the increasing portion in the liposome. The optimal formulation for animal study is that DMPC/PEG2000-DMPE/CH=50/5/45 at the weight ratio of drug/lipid=1/20 .
|
-
- HY-W440884
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-Ald, MW 3400 is a self-assemble polyPEG which spontaneously forms lipid bilayer in water. The polymer can be used to prepare nanoparticles or liposomse as a targeted drug carrier, such as mRNA vaccine. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
-
- HY-W127476
-
|
|
Biochemical Assay Reagents
|
Others
|
|
3-Nonenoic AcidIt is an organic compound belonging to the class of unsaturated fatty acids. It is a colorless liquid with a pungent smell and is commonly found in various foods such as cheese and butter. 3-Nonenoic AcidIt has various applications in the chemical and pharmaceutical industries, especially as an intermediate in the synthesis of various chemicals and drugs. In addition, it can also be used as a flavoring agent in food.
|
-
- HY-172465
-
|
|
Liposome
Integrin
|
Cancer
|
|
DSPE-PEG5000-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD). cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG5000-cRGD can be used for drug delivery .
|
-
- HY-W591632
-
|
Poly(ethylene glycol)-bis-amine (MW 1000)
|
Biochemical Assay Reagents
|
Cancer
|
|
PEG-bis-amine (MW 1000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
|
-
- HY-172464A
-
|
|
Liposome
Integrin
|
Cancer
|
|
DSPE-PEG3400-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD). cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG3400-cRGD can be used for drug delivery .
|
-
- HY-172463
-
|
|
Liposome
Integrin
|
Cancer
|
|
DSPE-PEG1000-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD). cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG1000-cRGD can be used for drug delivery .
|
-
- HY-167004A
-
|
|
Liposome
|
Others
|
|
IAJD249 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. IAJD249 can be used in the preparation of liposomes .
|
-
- HY-167004
-
|
|
Liposome
|
Others
|
|
IAJD93 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. IAJD93 can be used in the preparation of liposomes .
|
-
- HY-167012
-
|
|
Liposome
|
Others
|
|
306Oi9-cis2 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. 306Oi9-cis2 can be used in the preparation of liposomes .
|
-
- HY-167002
-
|
|
Liposome
|
Others
|
|
RM 137-15 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. RM 137-15 can be used in the preparation of liposomes .
|
-
- HY-167003
-
|
|
Liposome
|
Others
|
|
L16 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. L16 can be used in the preparation of liposomes .
|
-
- HY-167011
-
|
|
Liposome
|
Others
|
|
Al-28 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. Al-28 can be used in the preparation of liposomes .
|
-
- HY-167015
-
|
|
Liposome
|
Others
|
|
1O14 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. 1O14 can be used in the preparation of liposomes .
|
-
- HY-129698
-
|
CP162398
|
P-glycoprotein
|
Cancer
|
|
MS-073 (CP162398) is a P-glycoprotein (P-gp) inhibitor. MS-073 reverses multidrug resistance in drug-resistant cells by competitively inhibiting drug binding to P-glycoprotein .
|
-
- HY-B1346
-
-
- HY-138058
-
-
- HY-13047A
-
|
rel-Dexmecamylamine hydrochloride; rel-TC-5214 hydrochloride
|
nAChR
|
Cardiovascular Disease
|
|
rel-S-(+)-Mecamylamine hydrochloride is a known antihypertensive drug .
|
-
- HY-D0897
-
|
N-(1-Naphthyl)-3-aminopropanesulfonic acid sodium
|
Biochemical Assay Reagents
|
Others
|
|
3-(1-naphthalenylamino)-1-Propanesulfonic acid sodium salt is a compound belonging to the class of sulfonic acids. It is commonly used in the pharmaceutical industry as a buffer and stabilizer for drugs and other medicines. 3-(1-naphthalenylamino)-1-Propanesulfonic acid sodium salt helps to maintain the pH and stability of the drug, thereby improving the efficacy and shelf life of the drug. It can also be used as a dispersant in the production of nanoparticles and other materials.
|
-
- HY-172477
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG5000-YIGSR can be used for drug delivery .
|
-
- HY-172479
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG2000-F3 can be used for drug delivery .
|
-
- HY-172479A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG3400-F3 can be used for drug delivery .
|
-
- HY-172475
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG1000-YIGSR can be used for drug delivery .
|
-
- HY-172478
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG1000-F3 can be used for drug delivery .
|
-
- HY-W591476B
-
|
mPEG-SH (MW 750)
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-thiol (MW 750) modifies DNA thiolation for the synthesis of gold nanorods (AuNRs). Thiolated DNA can be loaded onto AuNR by the mPEG-SH/Tween 20 assisted method (Tween 20 and mPEG-SH repeatedly displace CTAB on the AuNR surface). DNA AuNRs have been widely used in nanostructure assembly, gene therapy, biosensing, and drug delivery.
|
-
- HY-172480
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-F3 is a PEG compound which composed of DSPE and a nucleolin targeting peptide (F3). F3 peptide can specifically bind to cell surface nucleolin and undergo an effective cell surface to nucleus transport. DSPE-PEG5000-F3 can be used for drug delivery .
|
-
- HY-W591476A
-
|
mPEG-SH (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-thiol (MW 3400) modifies DNA thiolation for the synthesis of gold nanorods (AuNRs). Thiolated DNA can be loaded onto AuNR by the mPEG-SH/Tween 20 assisted method (Tween 20 and mPEG-SH repeatedly displace CTAB on the AuNR surface). DNA AuNRs have been widely used in nanostructure assembly, gene therapy, biosensing, and drug delivery.
|
-
- HY-W440833
-
|
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
DSPE-PEG-Azide, MW 3400 is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelles formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form triazole bond. Reagent grade, for research use only.
|
-
- HY-W250721A
-
|
CBM 940
|
Biochemical Assay Reagents
|
Others
|
|
Carbomer 940 (CBM 940) is an acrylic acid polymer, which can be used as a thickening agent. Carbomer 940 provides a stable gel matrix, and exhibits good heat, light and microbial contamination resistance. Carbomer 940 shows high benzene content, which exists the risk as a carcinogen. Carbomer 940 facilitates the drug release and local application, which can be used in the pharmaceutical industry .
|
-
- HY-W591476C
-
|
mPEG-SH (MW 550)
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-thiol (MW 550) modifies DNA thiolation for the synthesis of gold nanorods (AuNRs). Thiolated DNA can be loaded onto AuNR by the mPEG-SH/Tween 20 assisted method (Tween 20 and mPEG-SH repeatedly displace CTAB on the AuNR surface). DNA AuNRs have been widely used in nanostructure assembly, gene therapy, biosensing, and drug delivery.
|
-
- HY-172476
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG2000-YIGSR can be used for drug delivery .
|
-
- HY-W591476D
-
|
mPEG-SH (MW 350)
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-thiol (MW 350) modifies DNA thiolation for the synthesis of gold nanorods (AuNRs). Thiolated DNA can be loaded onto AuNR by the mPEG-SH/Tween 20 assisted method (Tween 20 and mPEG-SH repeatedly displace CTAB on the AuNR surface). DNA AuNRs have been widely used in nanostructure assembly, gene therapy, biosensing, and drug delivery.
|
-
- HY-172476A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG3400-YIGSR can be used for drug delivery .
|
-
- HY-174279
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
MCC-AAQ-Exa is a drug-linker conjugates for ADC, obtained by condensing the linker with Exatecan (HY-13631) and can be used to prepare antibody-drug conjugates (ADCs). MCC is an ADC linker containing a maleimide fragment .
|
-
- HY-156299
-
|
|
ADC Linker
|
Cancer
|
|
NMS-P945 is an ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs). NMS-P945 is suitable for conjugation to mAbs with reproducible Drug Antibody Ratio (DAR) >3.5 .
|
-
- HY-115822
-
|
|
Amino Acid Decarboxylase
Glutathione S-transferase
|
Metabolic Disease
|
|
α-Fluoromethylhistidine dihydrochloride is a potent irreversible inhibitor of histidine decarboxylase (HDC) and glutathione S-transferase, demonstrating significant potential in studying histidine metabolism and drug metabolism processes. α-Fluoromethylhistidine dihydrochloride offers an effective approach to inhibit enzymes involved in these metabolic pathways. α-Fluoromethylhistidine dihydrochloride has implications for drug development by revealing off-target effects that may influence physiological drug metabolism and elimination mechanisms.
|
-
- HY-160247
-
|
|
Drug-Linker Conjugates for ADC
|
Others
|
|
Boc-Lys-PEG8-N-bis(D-glucose) (compound 89-5) is a drug linker that can be used in the synthesis of antibody-drug conjugates (ADCs) extracted from patent WO2023280227A2 .
|
-
- HY-172495
-
|
|
Liposome
Integrin
|
Cancer
|
|
DSPE-PEG3000-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG3000-iRGD can be used for drug delivery .
|
-
- HY-W440902
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-IA, MW 3400 is an iodoacetyll PEG lipid. The polymer can form lipid bilayer or micelles spontaneoulsy in water. The lipophilic tails can be used to encapsulate hydrophobic therapeutic agents while the hydrophilic head can be used to encapuslate hydrophilic drugs/nutrient, such as antibody, mRNA/DNA. The iodoacetyl group is reactive with thiol to produce a thioether linkage. Reagent grade, for research use only.
|
-
- HY-172493
-
|
|
Liposome
Integrin
|
Cancer
|
|
DSPE-PEG1000-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG1000-iRGD can be used for drug delivery .
|
-
- HY-172494
-
|
|
Liposome
Integrin
|
Cancer
|
|
DSPE-PEG2000-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG2000-iRGD can be used for drug delivery .
|
-
- HY-172494A
-
|
|
Liposome
Integrin
|
Cancer
|
|
DSPE-PEG3400-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG3400-iRGD can be used for drug delivery .
|
-
- HY-P4117
-
-
- HY-14840
-
-
- HY-159837
-
-
- HY-B1185
-
-
- HY-12770
-
-
- HY-W738358
-
|
|
Parasite
|
Infection
|
|
Chlorproguanil (hydrochloride) is an antimalarial drug. Chlorproguanil (hydrochloride) is a dichloro-derivative of chloroguanide .
|
-
- HY-118782
-
-
- HY-132180
-
-
- HY-119858
-
-
- HY-105641
-
-
- HY-G0010
-
-
- HY-111990
-
-
- HY-19813A
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
mDPR-Val-Cit-PAB-MMAE TFA is a drug-linker conjugate for ADC (Drug-Linker Conjugates for ADC), consisting of a tubulin polymerization inhibitor MMAE (HY-15162) and an ADC linker (peptide Val-Cit- PAB) composition [1] .
|
-
- HY-B0580
-
|
RS37619
|
COX
Apoptosis
|
Inflammation/Immunology
Cancer
|
|
Ketorolac (RS37619) is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2. Ketorolac tromethamine is used as 0.5% ophthalmic solution for the research of allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Ketorolac tromethamine is also a DDX3 inhibitor that can be used for cancer research .
|
-
- HY-B0580D
-
|
RS37619 hydrochloride
|
COX
Apoptosis
|
Inflammation/Immunology
Cancer
|
|
Ketorolac (RS37619) hydrochloride is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2. Ketorolac hydrochloride tromethamine is used as 0.5% ophthalmic solution for the research of allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Ketorolac hydrochloride tromethamine is also a DDX3 inhibitor that can be used for cancer research .
|
-
- HY-W127443
-
|
|
Biochemical Assay Reagents
|
Others
|
|
3-Heptenoic acidIt is an organic compound belonging to the class of unsaturated fatty acids. It has a strong, unpleasant smell and is commonly found in a variety of foods, such as beer and dairy products. 3-Heptenoic acidIt has various applications in the fragrance and fragrance industry, especially as a fragrance and flavoring agent in products such as perfume, cologne and food additives. In addition, it can also be used as an intermediate in the synthesis of various chemicals and drugs.
|
-
- HY-172488A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG3400-K237 can be used for drug delivery .
|
-
- HY-172489
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG5000-K237 can be used for drug delivery .
|
-
- HY-172488
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG2000-K237 can be used for drug delivery .
|
-
- HY-172487
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG1000-K237 can be used for drug delivery .
|
-
- HY-N7131
-
|
|
Fluorescent Dye
|
Others
|
|
Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λexc=450 nm, λem=505 nm) .
|
-
- HY-160182
-
-
- HY-B1016
-
-
- HY-12771
-
|
Mebeverine metabolite O-desmethyl Mebeverine acid
|
Drug Metabolite
|
Neurological Disease
|
|
O-desmethyl Mebeverine acid is a metabolite of Mebeverine, which is a musculotropic antispasmodic drug.
|
-
- HY-W779009
-
|
|
Bacterial
|
Others
|
|
[1-13Cglc]Lactose monohydrate is an isotopic labeling drug .
|
-
![[1-13Cglc]Lactose monohydrate](//file.medchemexpress.com/product_pic/hy-w779009.gif)
- HY-B1177
-
|
|
Parasite
|
Infection
|
|
Crotamiton is a drug that is used both as a scabicidal (for treating scabies) and as a general antipruritic.
|
-
- HY-129365
-
|
|
ADC Linker
|
Cancer
|
|
SNPB is a cleavable linker that is used for making antibody-drug conjugate (ADC).
|
-
- HY-101689
-
-
- HY-13631O
-
-
- HY-112624K
-
|
Dextran 5; Dextran D5; Dextran T5(MW 4500-5500)
|
Apoptosis
Autophagy
|
Others
|
|
Dextran T5 (MW 5,000) is a sulfated polysaccharide anti-apoptotic and autophagic agent. Dextran T5 (MW 5,000) has sulfated groups and interacts with cell membranes by mimicking endogenous glycosaminoglycans, inhibiting the mitochondrial apoptotic pathway and delaying DNA fragmentation to exert anti-apoptotic activity. Dextran T5 (MW 5,000) also promotes the conversion of LC3-I to LC3-II and the formation of autophagosomes to activate the autophagic pathway. Dextran T5 (MW 5,000) can prolong the survival cycle of CHO cells and increase the production of recombinant erythropoietin (EPO). The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
|
-
- HY-170512
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Mal-GGFG-PAB-MMAE (Compound 8) is a drug-linker conjugate, which is composed of the mitotic inhibitor MMAE (HY-15162) and the linker Mal-GGFG-PAB. Mal-GGFG-PAB-MMAE can be used for synthesis of antibody-drug conjugate .
|
-
- HY-B0580C
-
|
RS37619 hemicalcium
|
COX
Apoptosis
|
Inflammation/Immunology
Cancer
|
|
Ketorolac (RS37619) hemicalcium is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2. Ketorolac tromethamine is used as 0.5% ophthalmic solution for the research of allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Ketorola chemicalcium is also a DDX3 inhibitor that can be used for cancer research .
|
-
- HY-140696E
-
|
mPEG-Hydroxy (MW 1000); Polyethylene glycol monomethyl ether (MW 1000)
|
PROTAC Linkers
|
Cancer
|
|
m-PEG-OH (MW 1000) can be used as a macroinitiator to participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles to deliver active drugs. Paclitaxel (HY-B0015), a hydrophobic anticancer agent encapsulated in micelles, has stronger cancer-killing activity than free Paclitaxel. And it accumulates preferentially in tumor tissues and has only limited distribution in healthy organs.
|
-
- HY-143702
-
|
NBD-DOTAP
|
Fluorescent Dye
Liposome
|
Inflammation/Immunology
Cancer
|
|
Fluorescent DOTAP (NBD-DOTAP) is a cationic lipid which can be used for nucleic acid and protein delivery. Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm). Fluorescent DOTAP can be used for gene delivery systems, drug delivery, as well as cell imaging and nanocarrier tracking. Fluorescent DOTAP is an ideal candidate for both biological and pharmaceutical formulation (e.g. co-delivery of vaccines) research .
|
-
- HY-173385
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
Cholesteryl-PEG1000-Azide is a lipid that can be used for drug delivery. Cholesteryl-PEG1000-Azide is attached to the cholesterol backbone with a PEG unit on one side and an azide unit on the other side of the PEG. Cholesteryl-PEG1000-Azide contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group .
|
-
- HY-155902D
-
|
Maleimide-PEG-Hydroxy (MW 10000)
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-OH (MW 10000) (Maleimide-PEG-Hydroxy (MW 10000)) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG-OH (MW 10000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
|
-
- HY-140696C
-
|
mPEG-Hydroxy (MW 20000); Polyethylene glycol monomethyl ether (MW 20000)
|
PROTAC Linkers
|
Cancer
|
|
m-PEG-OH (MW 20000) can be used as a macroinitiator to participate in the synthesis of amphiphilic block copolymers. Nanoscale micelles can be prepared by using amphiphilic block copolymers to deliver active drugs. Paclitaxel (HY-B0015), a hydrophobic anticancer agent encapsulated in micelles, has stronger activity in killing cancer cells than free Paclitaxel. And it preferentially accumulates in tumor tissue with only limited distribution in healthy organs.
|
-
- HY-W440901
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-SPDP, MW 5000 is an amphiphilic polyPEG which forms lipid bilayer in water. It can be used to encapsualte therapeutic agents. The core can encapsulate hydrophilic nutrients, such as protein/peptide and mRNA/DNA/siRNA etc. while the lipid bilayer can solubilize hydrophobic drugs, such as doxorubicin, curcumin etc. The SPDP moiety can react with thiol molecule to form a disulfide bond. Reagent grade, for research use only.
|
-
- HY-140696D
-
|
mPEG-Hydroxy (MW 10000); Polyethylene glycol monomethyl ether (MW 10000)
|
PROTAC Linkers
|
Cancer
|
|
m-PEG-OH (MW 10000) can be used as a macroinitiator to participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles to deliver active drugs. Paclitaxel (HY-B0015), a hydrophobic anticancer agent encapsulated in micelles, has stronger activity in killing cancer cells than free Paclitaxel. And it preferentially accumulates in tumor tissue with only limited distribution in healthy organs.
|
-
- HY-155902E
-
|
Maleimide-PEG-Hydroxy (MW 20000)
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-OH (MW 20000) (Maleimide-PEG-Hydroxy (MW 20000)) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG-OH (MW 20000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
|
-
- HY-155902H
-
|
Maleimide-PEG-Hydroxy (MW 40000)
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-OH (MW 40000) (Maleimide-PEG-Hydroxy (MW 40000)) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG-OH (MW 40000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
|
-
- HY-155902C
-
|
Maleimide-PEG-Hydroxy (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG-OH (MW 3400) (Maleimide-PEG-Hydroxy (MW 3400)) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG-OH (MW 3400) can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
|
-
- HY-176210
-
|
|
Fungal
Cytochrome P450
|
Infection
|
|
CYP51-IN-24 (Compound 22) is a Sterol 14α-Demethylase (CYP51) inhibitor. CYP51-IN-24 exhibits potent inhibitory activity against wild-type and drug-resistant fungi. CYP51-IN-24 inhibits ergosterol biosynthesis by binding to the fungal CYP51 enzyme. CYP51-IN-24 can be used in research and drug development against drug-resistant fungal infections .
|
-
- HY-150554
-
|
|
Bacterial
|
Infection
|
|
Antitubercular agent-29 (compound 6xa) is a potent agent resistant (DR) Mycobacterium tuberculosis (Mtb) inhibitor with MIC of 0.03 μg/mL against agent-susceptible (DS)-Mtb strains, MIC of 0.03-0.06 μg/mL against DR-Mtb strains, and favourable selectivity (SI>40) against Vero cells .
|
-
- HY-163363
-
|
|
Adrenergic Receptor
|
Cancer
|
|
β-AR antagonist 2 (compound 43) is an antagonist of β-AR (IC50: 0.17 μM). β-AR-IN-1 inhibits the growth of mouse A549 xenograft tumors and shows cardioprotective efficacy against DOX-induced HF in C57 mice .
|
-
- HY-149423
-
|
|
PI5P4K
|
Cancer
|
|
PI5P4K-β-IN-1 (compound vs1) is a potent inhibitor of PI5P4K-β (IC50: 0.80 μM) .
|
-
- HY-P10895
-
|
|
Biochemical Assay Reagents
|
Others
|
|
HR97 TFA is a cell-penetrating peptide that can be combined with engineered melanin to prepare eye drops HR97-SunitiGel. The peptide-drug conjugate in HR97-SunitiGel can provide sustained ocular drug delivery .
|
-
- HY-144278
-
|
|
Bacterial
|
Infection
Inflammation/Immunology
|
|
Anti-MRSA agent 1 (Compound 13d) is a wonderful MRSA (MIC = 0.5 μg/mL) inhibitor. Anti-MRSA agent 1 (Compound 13d) could effectually relieve the development of MRSA resistance .
|
-
- HY-123681
-
-
- HY-108228
-
-
- HY-P4565
-
|
|
Cathepsin
|
Others
|
|
Phe-Arg-Arg-Gly is a polypeptide that can be used for agent coupling .
|
-
- HY-123526
-
|
NSC305458
|
BCRP
|
Cancer
|
|
NSC 265473 is an ABCG2 substrate .
|
-
- HY-W012860
-
-
- HY-126498
-
|
|
ADC Linker
|
Cancer
|
|
PDEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC).
|
-
- HY-42146
-
|
|
ADC Linker
|
Cancer
|
|
BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-129376
-
|
|
ADC Linker
|
Cancer
|
|
Sulfo-SNPB is a cleavable linker that is used for making antibody-drug conjugate (ADC).
|
-
- HY-B0992
-
-
- HY-148399
-
-
- HY-160234
-
|
|
ADC Linker
|
Cancer
|
|
mc-vc-PAB-PBD is a drug linker for the preparation of TDC and ADC .
|
-
- HY-19697
-
-
- HY-B0270
-
-
- HY-126519
-
|
|
ADC Linker
|
Cancer
|
|
PDdEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC).
|
-
- HY-176509D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-CHO ammonium (MW 10000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO ammonium (MW 10000) can be used for drug delivery .
|
-
- HY-176509B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-CHO ammonium (MW 3400) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO ammonium (MW 3400) can be used for drug delivery .
|
-
- HY-176509C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-CHO ammonium (MW 5000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO ammonium (MW 5000) can be used for drug delivery .
|
-
- HY-176509
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-CHO ammonium (MW 1000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO ammonium (MW 1000) can be used for drug delivery .
|
-
- HY-176509E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-CHO ammonium (MW 20000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO ammonium (MW 20000) can be used for drug delivery .
|
-
- HY-176509H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-CHO ammonium (MW 40000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO ammonium (MW 40000) can be used for drug delivery .
|
-
- HY-176509A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-CHO ammonium (MW 2000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO ammonium (MW 2000) can be used for drug delivery .
|
-
- HY-W127386
-
|
3-Dodecyloxypropane-1,2-diol
|
Biochemical Assay Reagents
|
Others
|
|
1-O-Dodecyl-rac-glycerol is a class of organic compounds belonging to the class of racemic glycerol derivatives. It consists of a dodecyl chain attached to the sn-1 position of the racemic glycerol molecule. 1-O-Dodecyl-rac-glycerol has various applications in the pharmaceutical industry, especially as an intermediate in the synthesis of lipid drug delivery systems and membranes. Additionally, it has potential use as an emulsifier and surfactant in cosmetic and personal care products.
|
-
- HY-171562
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
Cholesterol-SA-PEG-Azide (MW 2000) is a lipid that can be used for drug delivery. Cholesterol-SA-PEG-Azide (MW 2000) contains Cholesterol (HY-N0322), Succinic acid (HY-N0420), PEG units and an azide group. Cholesterol-SA-PEG-Azide (MW 2000) contains an azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group .
|
-
- HY-144694
-
|
|
HSP
HDAC
Fungal
|
Infection
|
|
HDAC/HSP90-IN-3 (compound J5) is a potent and selective fungal Hsp90 and HDAC dual inhibitor, with IC50 values of 0.83 and 0.91 μM, respectively. HDAC/HSP90-IN-3 shows antifungal activity against azole resistant C. albicans. HDAC/HSP90-IN-3 can suppress important virulence factors and down-regulate drug-resistant genes ERG11 and CDR1 .
|
-
- HY-D0040
-
|
Fluorexon
|
Fluorescent Dye
|
Others
|
|
Calcein is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems .
|
-
- HY-W440881A
-
|
|
Liposome
|
|
|
DSPE-PEG-C2-DBCO (sodium) (MW 3400) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG-C2-DBCO(sodium) (MW 3400) can be used in drug delivery research .
|
-
- HY-126667
-
|
|
ADC Linker
|
Cancer
|
|
SC-Val-Cit-PAB is a cleavable ADC linker for antibody-drug conjugates (ADCs).
|
-
- HY-17481
-
-
- HY-129369
-
|
|
ADC Linker
|
Cancer
|
|
SPDMB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) .
|
-
- HY-B0101B
-
-
- HY-B0101A
-
-
- HY-129366
-
|
|
ADC Linker
|
Cancer
|
|
PDB-Pfp is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-12448
-
|
|
ADC Linker
|
Cancer
|
|
SPDB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) .
|
-
- HY-129368
-
|
|
ADC Linker
|
Cancer
|
|
SPDMV is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) .
|
-
- HY-122983
-
-
- HY-129375
-
|
|
ADC Linker
|
Cancer
|
|
SNPB-sulfo-Me is a cleavable linker that is used for making antibody-drug conjugate (ADC).
|
-
- HY-44235
-
|
|
ADC Linker
|
Cancer
|
|
MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).
|
-
- HY-129373
-
|
|
ADC Linker
|
Cancer
|
|
SPDMV-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).
|
-
- HY-126530
-
-
- HY-17484
-
|
CP 65703
|
COX
|
Inflammation/Immunology
|
|
Ampiroxicam(CP65703) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.
|
-
- HY-W156596
-
|
|
Drug Intermediate
|
Others
|
|
3-Methoxybenzothioamide is an active small molecule, that can be ussed as drug intermediate .
|
-
- HY-W017393
-
|
4-Methylbenzenecarbothioamide; 4-Methylbenzenethioamide
|
Drug Intermediate
|
Others
|
|
thio-p-Toluamide is a cyclic thioamide building block used in drug discovery chemistry.
|
-
- HY-N0402
-
-
- HY-172273
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG1000-M2pep can be used for drug delivery .
|
-
- HY-173606
-
|
|
Liposome
|
Others
|
|
DSPE-PEG2000-Azide ammonium is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery . DSPE-PEG2000-Azide ammonium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-172273B
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG5000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG5000-M2pep can be used for drug delivery .
|
-
- HY-172273A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG2000-M2pep can be used for drug delivery .
|
-
- HY-172273C
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG3400-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG3400-M2pep can be used for drug delivery .
|
-
- HY-173381
-
|
Cholesteryl biotinyl(polyethyleneglycol)-2000 carbamate
|
Biochemical Assay Reagents
|
Others
|
|
Cholesteryl-PEG2000-Biotin (Cholesteryl biotinyl(polyethyleneglycol)-2000 carbamate) is a lipid product. Cholesteryl-PEG2000-Biotin is a cholesterol backbone attached to one side of a PEG unit and a Biotin unit on the other side. Biotin is an enzyme cofactor that can be used to label proteins, and PEG is a low-toxic, hydrophilic, water-soluble polymer. Cholesteryl-PEG2000-Biotin can be used for drug circulation time studies .
|
-
- HY-W250313
-
|
PLA
|
Biochemical Assay Reagents
|
Others
Cancer
|
|
Polylactic acid (PLA) is a biodegradable and biocompatible polymer widely used as a carrier for drug delivery systems and a structural material for tissue engineering and medical implants. Polylactic acid acts as a controlled release matrix through the hydrolysis mechanism of ester bonds, gradually releasing the encapsulated drug and metabolizing to non-toxic lactic acid. Polylactic acid has adjustable degradation rate, mechanical properties and the ability to composite with other polymers, and can be used in local or systemic drug delivery, orthopedic fixation devices and 3D printed bone regeneration scaffolds[1][2].
|
-
- HY-172808
-
|
|
Cannabinoid Receptor
Cytochrome P450
|
Metabolic Disease
|
|
BNS808 is an orally active and selective cannabinoid-1 receptor (CB1R) antagonist (IC50 = 0.8 nM) with notable CB2R selectivity and minimal brain penetration. BNS808 is studied in research on obesity and its associated metabolic complications, such as metabolic dysfunctional-associated steatotic liver disease (MASLD). BNS808 has reduced free drug availability for CNS entry, enhancing safety and minimizing drug-drug interactions through high plasma binding .
|
-
- HY-P4192
-
|
|
ADC Linker
|
Cancer
|
|
Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit .
|
-
- HY-16569
-
|
|
Microtubule/Tubulin
NOD-like Receptor (NLR)
Autophagy
Apoptosis
|
Cancer
|
|
Colchicine, an orally active alkaloid, is a potent tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs). Colchicine prevents non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome. Colchicine has extensive anti-inflammatory, immunosuppressive and strong anti-fibrosis effects and has the potential for gouty arthritis research .
|
-
- HY-45672
-
|
|
ADC Linker
|
Cancer
|
|
Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .
|
-
- HY-W009247R
-
|
N-Demethylolanzapine (Standard); LY170055 (Standard)
|
Endogenous Metabolite
Reference Standards
|
Neurological Disease
|
|
N-Desmethylolanzapine (Standard) is the analytical standard of N-Desmethylolanzapine. This product is intended for research and analytical applications. N-Desmethylolanzapine is an antipsychotic drug.
The formation of N-Desmethylolanzapine correlates with the level and activity
of human liver flavin-containing monooxygenase (FMO3). N-Desmethylolanzapine
can be used in the study of antipsychotic drugs .
|
-
- HY-133542
-
|
|
ADC Linker
|
Cancer
|
|
Dimethylamine-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-114697
-
-
- HY-129370
-
|
|
ADC Linker
|
Cancer
|
|
SPDB-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) .
|
-
- HY-B0482
-
|
TVX 1322
|
COX
|
Inflammation/Immunology
|
|
Acemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.
|
-
- HY-137157
-
-
- HY-150043A
-
|
|
ADC Linker
|
Cancer
|
|
MDTF is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130111
-
|
|
ADC Linker
|
Cancer
|
|
DMAC-SPP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-N15059
-
|
|
Bacterial
|
Infection
|
|
Cissetin shows activity against Gram-positive bacteria, including drug-resistant strains .
|
-
- HY-140014
-
|
|
ADC Linker
|
Cancer
|
|
Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-160157
-
-
- HY-101151
-
|
|
ADC Linker
|
Cancer
|
|
sulfo-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-128970
-
|
|
ADC Linker
|
Cancer
|
|
Mp-polymer ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W010611
-
|
3-Methylcrotonic acid; 3-Methylbut-2-enoic acid
|
Bacterial
|
Infection
|
|
3,3-Dimethylacrylic acid is an active small molecule, that can be used as drug intermediate .
|
-
- HY-133540
-
-
- HY-B1048
-
|
Paraniazide; Pasiniazide; Isonicotinic acid hydrazide p-aminosalicylate
|
Bacterial
|
Inflammation/Immunology
|
|
Pasiniazid is an anti-TB and anti-leprosy drug, used to treat various types of TB and leprosy.
|
-
- HY-126349
-
|
|
ADC Linker
|
Cancer
|
|
DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140098
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Cystamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-118759
-
-
- HY-B0174
-
-
- HY-106749
-
-
- HY-133550
-
|
|
ADC Linker
|
Cancer
|
|
DMAC-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W775009
-
|
|
COX
|
Inflammation/Immunology
|
|
Imidazole salicylate is a nonsteroidal anti-inflammatory drug that can be used to study cirrhosis and ascites .
|
-
- HY-126405
-
|
|
ADC Linker
|
Cancer
|
|
SMPT is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-101014
-
|
|
Biochemical Assay Reagents
|
Infection
|
|
Octanoylcarnitine chloride is a homolog of acetylcarnitine chloride. Octanoylcarnitine chloride can enhance absorption of drugs from gastrointestinal tract .
|
-
- HY-17616
-
|
LEO 43204
|
Drug Metabolite
|
Others
|
|
Ingenol disoxate (LEO 43204) is a drug metabolite, that exhibits potential in ameliorating actinic keratosis .
|
-
- HY-126531
-
|
|
ADC Linker
|
Cancer
|
|
DMAC-PDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-155870
-
-
- HY-153180
-
-
- HY-128927
-
|
|
ADC Linker
|
Cancer
|
|
Mc-Leu-Gly-Arg is a cleavable ether linker for antibody-drug conjugates (ADC) design.
|
-
- HY-W071006
-
|
2,5-Dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate
|
ADC Linker
|
Cancer
|
|
PPC-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-133543
-
|
|
ADC Linker
|
Cancer
|
|
SPDP-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-153947
-
-
- HY-B0580R
-
|
RS37619 (Standard)
|
Reference Standards
COX
Apoptosis
|
Inflammation/Immunology
Cancer
|
|
Ketorolac (Standard) is the analytical standard of Ketorolac. This product is intended for research and analytical applications. Ketorolac (RS37619) is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2. Ketorolac tromethamine is used as 0.5% ophthalmic solution for the research of allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Ketorolac tromethamine is also a DDX3 inhibitor that can be used for cancer research .
|
-
- HY-13631F
-
|
|
Drug-Linker Conjugates for ADC
Topoisomerase
|
Cancer
|
|
Gly-Gly-Phe-Gly-NH-O-CO-Exatecan, as a drug-linker conjugate composed of linker Gly-Gly-Phe-Gly-NH-O-CO and Exatecan, can be used to prepare antibody conjugate drugs. Exatecan is a DNA topoisomerase I inhibitor that can be used in cancer research .
|
-
- HY-49929
-
|
|
ADC Linker
|
Cancer
|
|
MC-GGFG-NH-CH2-O-CH2-cyclopropane-COOH is an ADC linker that can be combined with the cytotoxic Camptothecin (HY-16560) to form ADC-related drug-linker conjugates (Drug-Linker Conjugates for ADC ).MC-GGFG-NH-CH2-O-CH2-cyclopropane-COOH is conjugated to Camptothecin, which can further bind to the antibody Trastuzumab (HY-P9907) to form Antibody-Drug Conjugates (ADCs) .
|
-
- HY-401424
-
|
Polyoxyethylene(36) Castor Oil; PEG-36 Castor Oil
|
Biochemical Assay Reagents
|
Others
|
|
Cremophor EL-36 is a nonionic surfactant, mainly used as a solubilizing carrier for poorly soluble Paclitaxel (HY-B0015). The functions of Cremophor EL-36 include: 1) affecting pharmacokinetics by encapsulating drugs in micelles, changing drug distribution and clearance; 2) activating the complement system and inducing allergic reactions; 3) binding to lipoproteins and interfering with lipid metabolism. Cremophor EL-36 increases drug solubility through micellization, while mediating toxicity through complement activation and lipoprotein interactions .
|
-
- HY-W731085
-
|
|
ADC Linker
|
Cancer
|
|
MC-GGFG-NH-CH2-O-CH2-(s-cyclopropane)-COOH is an ADC linker that can be combined with the cytotoxic Camptothecin (HY-16560) to form an ADC-related drug-linker conjugate (Drug- Linker Conjugates for ADC).MC-GGFG-NH-CH2-O-CH2-cyclopropane-COOH is conjugated to Camptothecin, which can further bind to the antibody Trastuzumab (HY-P9907) to form Antibody-Drug Conjugates (ADCs) .
|
-
- HY-W131101
-
|
|
Liposome
|
Others
|
|
Sorbitan tristearate is a non-ionic surfactant, with a synergistic effect on skin permeability. Sorbitan tristearate can be used as an excipient, such as emulsifier. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
|
-
- HY-10550B
-
|
XR9576 dimesylate
|
P-glycoprotein
|
Cardiovascular Disease
Others
|
|
Tariquidar dimesylate (XR9576 dimesylate) is a P-glycoprotein (P-gp) inhibitor. Tariquidar dimesylate increases the concentration of the drug in the brain by binding to P-glycoprotein, preventing it from transporting the drug from inside to outside the brain. Tariquidar dimesylate can be used in the study of blood-brain barrier penetration and multidrug resistance .
|
-
- HY-155190
-
|
|
Bacterial
|
Infection
|
|
Antitubercular agent-39 (Compound P1) is a potent antitubercular agent. Antitubercular agent-39 is active against drug-resistant strains and drug-susceptible clinical isolates. Antitubercular agent-39 inhibits Mtb strain H37Rv with a MIC less than 1 μM .
|
-
- HY-141607
-
|
BT-062; nBT062-DM4
|
Antibody-Drug Conjugates (ADCs)
Bacterial
|
Cancer
|
|
Indatuximab ravtansine (BT-062) is an antibody-drug conjugate (ADC) (Antibody-Drug Conjugates (ADCs)) based on a murine/human chimeric form of B-B4 (specific for CD138), linked to the maytansinoid agent DM4 by disulphide bonds. Indatuximab ravtansine shows anti-tumor activities .
|
-
- HY-126495A
-
|
|
ADC Linker
|
Cancer
|
|
Sulfo-LC-SPDP sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W011541
-
|
Iodoacetic acid N-hydroxysuccinimide ester; N-Succinimidyl Iodoacetate
|
ADC Linker
|
Cancer
|
|
SIA Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140987
-
|
|
ADC Linker
|
Cancer
|
|
5-Maleimidovaleric acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130110
-
|
|
ADC Linker
|
Cancer
|
|
Sulfo-DMAC-SPP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W004650
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TETA hydrochloride hydrate is an effective selective chelating agent for copper (II). TETA hydrochloride hydrate can be used for drug coupling .
|
-
- HY-173292
-
-
- HY-41919
-
|
mDPR(boc); (S)-MALEOYL-DPR(BOC)-OH·DCHA
|
ADC Linker
|
Cancer
|
|
Mal-L-PA-NH-Boc is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-44246
-
|
|
ADC Linker
|
Cancer
|
|
MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
|
-
- HY-141158
-
|
|
ADC Linker
|
Cancer
|
|
N-(Iodoacetamido)-Doxorubicin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-155870A
-
-
- HY-19376
-
|
|
FAK
|
Cancer
|
|
NAMI-A is a ruthenium-based drug characterised by the selective activity against tumour metastases, inhibits the adhesion and migration.
|
-
- HY-138327
-
|
|
ADC Linker
|
Cancer
|
|
16-Bismesyloxyhexane is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-126364
-
|
|
ADC Linker
|
Cancer
|
|
Mc- Val- Ala- PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-130099
-
|
|
ADC Linker
|
Cancer
|
|
Ald-Ph-amido-PEG2 is a noncleavable ADC linker for antibody-drug conjugate .
|
-
- HY-160790
-
|
|
ADC Linker
|
Cancer
|
|
β-Glu-PNP is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-164732
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Lys(DOTA)-OH is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-100358
-
|
|
Parasite
|
Infection
|
|
AQ-13 dihydrochloride is an aminoquinoline antimalarial agent that is effective against drug-resistant strains of Plasmodium falciparum.
|
-
- HY-140096
-
|
|
ADC Linker
|
Cancer
|
|
Aminoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-129353
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Phe-(Alloc)Lys-PAB-PNP is a used as a cleavable linker for antibody-drug conjugates (ADC).
|
-
- HY-126496
-
|
|
ADC Linker
|
Cancer
|
|
PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).
|
-
- HY-W096127
-
|
|
ADC Linker
|
Cancer
|
|
Biotin-sar-oh is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-129367
-
|
|
ADC Linker
|
Cancer
|
|
NO2-SPP is a cleavable linker that is used for making antibody-drug conjugate (ADC).
|
-
- HY-169353
-
|
|
ADC Linker
|
Cancer
|
|
Mal-Exo-EEVC is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) .
|
-
- HY-75887
-
|
|
Biochemical Assay Reagents
|
Others
|
|
5-Nitrosalicylaldehyde is a nitroaromatic aldehyde compound that is mainly used in photochromic compounds and drug synthesis .
|
-
- HY-128929
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-PEA (Example 1-2) is a used as a cleavable linker for antibody-drug conjugates (ADC) .
|
-
- HY-140122
-
|
|
ADC Linker
|
Cancer
|
|
THP-SS-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-168943A
-
-
- HY-E70398
-
|
L-Iditol dehydrogenase; Polyol dehydrogenase; SDH
|
Biochemical Assay Reagents
|
Others
|
|
Sorbitol dehydrogenase is an oxidoreductase. Sorbitol dehydrogenase can be used as a marker for drug-induced liver injury .
|
-
- HY-129352
-
|
|
ADC Linker
|
Cancer
|
|
Cbz-Phe-(Alloc)Lys-PAB-PNP is an cleavable linker for antibody-drug conjugates (ADC) design.
|
-
- HY-153642
-
-
- HY-169352
-
|
|
ADC Linker
|
Cancer
|
|
Mal-Exo-EVC is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) .
|
-
- HY-129360
-
|
|
ADC Linker
|
Cancer
|
|
Ala-Ala-Asn-PAB is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs) .
|
-
- HY-W013021
-
-
- HY-76210
-
-
- HY-131084
-
|
|
ADC Linker
|
Cancer
|
|
DMAC-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-132162
-
|
|
ADC Cytotoxin
|
Cancer
|
|
7-MAD-MDCPT, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs) .
|
-
- HY-160408
-
|
|
ADC Linker
|
Cancer
|
|
Mal-GGG-Bal-NHS ester is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-20560
-
|
|
ADC Linker
|
Cancer
|
|
(Ac)Phe-Lys(Alloc)-PABC-PNP is an useful cleavable chemical linker in antibody drug conjugates.
|
-
- HY-W002213
-
|
|
ADC Linker
|
Cancer
|
|
N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140129
-
|
|
ADC Linker
|
Cancer
|
|
NHS-SS-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-150043
-
|
|
ADC Linker
|
Cancer
|
|
MDTF free acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-44235A
-
|
|
ADC Linker
|
Cancer
|
|
MC-Gly-Gly-D-Phe is a cleavable linker used for sythesis of antibody-drug conjugates (ADC).
|
-
- HY-117742
-
|
|
Bacterial
|
Others
|
|
DA-7867 is an antibacterial compound with activity against a wide range of bacteria, including drug-resistant bacteria. DA-7867 shows promising antibacterial activity against some clinically important pathogens, including drug-resistant bacteria. It is an amide analog of Tedizolid, reflecting the potential use of tetrazoles in the development of new antibacterial agents.
|
-
- HY-N6611
-
|
|
IGF-1R
|
Infection
Inflammation/Immunology
Cancer
|
|
Chimaphilin is an IGF-1R inhibitor (IC50: 0.086 μM). Chimaphilin has antifungal, antioxidant and anticancer activities. Chimaphilin inhibits the growth of both drug-sensitive and drug-resistant osteosarcoma cell lines. Chimaphilin can induce cancer cell apoptosis. Chimaphilin is a main component of pyrola .
|
-
- HY-176415
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Cys-MC-GGFG-Dxd is a conjugate of Cys and Deruxtecan (HY-13631E). Cys-MC-GGFG-Dxd is a linker-toxin building block in antibody-drug conjugates (ADCs) used to link antibody Cys residues to cytotoxic drugs. Cys-MC-GGFG-Dxd can be used in cancer research .
|
-
- HY-P99238
-
|
|
ADC Antibody
|
Inflammation/Immunology
Cancer
|
|
Rolinsatamab is a IgG1κ type chimeric antibody targeting to PRLR (prolactin receptor). Rolinsatamab can be conjugated with pyrrolobenzodiazepine (PDB) dimer SGD-1882 (HY-101127) via a cleavable maleimidocaproyl type linker, to form an antibody-drug conjugate, Rolinsatamab talirine. One Rolinsatamab talirine has an average of 2 site-specific drug attachment engineered cysteines (S239C). The linker equips the valine-alanine dipeptide, as cathepsine B cleavage site. on an average of 2 site-specific drug attachment engineered cysteines (S239C) .
|
-
- HY-W010507
-
|
Methyl (R)-(-)-3-hydroxybutyrate
|
Biochemical Assay Reagents
|
Others
|
|
(R)-Methyl 3-hydroxybutanoate, (R)-Methyl 3-hydroxybutanoate is an enantiomer, from the perspective of the methyl (-CH3) group, the hydroxyl (-OH) group on the third carbon atom The group faces to the right, a colorless transparent liquid, soluble in organic solvents such as ethanol and ether, insoluble in water, (R)-Methyl 3-hydroxybutanoate is usually used to synthesize various organic compounds (including drugs, agricultural chemicals and flavoring agents) It can also be used as a chiral auxiliary in asymmetric synthetic reactions involving the formation of chemical bonds in a stereoselective manner.
|
-
- HY-17509
-
|
SC 046; SC 46; SC 59046
|
COX
Apoptosis
|
Inflammation/Immunology
|
|
Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID).
|
-
- HY-W590676
-
|
TMCL
|
Liposome
|
Others
|
|
Tetramyristoylcardiolipin (TMCL) is an anionic lipid. Tetramyristoylcardiolipin can be used to study cell membrane function and drug delivery .
|
-
- HY-P3193A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cyclic nona-L-arginine hydrochloride, a nonaarginine peptide used for drug delivery, translocates faster than their linear counterparts .
|
-
- HY-B0967
-
|
|
Bacterial
|
Infection
|
|
Phthalylsulfacetamide is a sulfa drug, after oral administration, slowly decompose in the intestine,and release sulfacetamide ,generating antibacterial effect.
|
-
- HY-Y1326
-
-
- HY-W019543
-
|
|
ADC Linker
|
Cancer
|
|
Disuccinimidyl suberate Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-171126
-
-
- HY-23641
-
|
|
ADC Linker
|
Cancer
|
|
NH-bis(C1-Boc)is a uncleavable linker used for antibody-drug conjugates (ADC).
|
-
- HY-129485
-
-
- HY-130112
-
|
NHS-C4-MTS
|
ADC Linker
|
Cancer
|
|
N-Succinimidyloxycarbonylpropyl methanethiosulfonate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-B1079
-
-
- HY-124329
-
|
|
ADC Linker
|
Cancer
|
|
BS3 Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-101153
-
|
|
ADC Linker
|
Cancer
|
|
MC-Val-Ala-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-N11874
-
|
|
Bacterial
|
Infection
|
|
Staphyloferrin A is a siderophore protein that can be combined with antibiotics to study drug-resistant bacteria that cause skin diseases .
|
-
- HY-135501
-
-
- HY-140138
-
|
|
ADC Linker
|
Cancer
|
|
PC SPDP-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W097109A
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-(D-Phe)-Osu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W023121
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Gly-Gly-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-76772A
-
|
(+)-SNI-2011; (+)-AF102B hydrochloride hemihydrate
|
mAChR
|
Neurological Disease
|
|
(+)-Cevimeline hydrochloride hemihydrate ((+)-SNI-2011), a potent muscarinic receptor agonist, is a candidate therapeutic drug for xerostomia in Sjogren's syndrome.
|
-
- HY-141141
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-117409
-
|
|
ADC Linker
|
Cancer
|
|
Aminoethyl-SS-ethylalcohol is a glutathione cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-135418
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Asp-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-140140
-
|
|
ADC Linker
|
Cancer
|
|
PC Mal-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-138322
-
|
|
ADC Linker
|
Cancer
|
|
N-trifluoroacetyl-β-alanyl chloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-159794
-
|
|
ADC Linker
|
Cancer
|
|
Azido-methyltetrazine di-arm linker is a multivalent ADC linker for the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-129362
-
|
|
ADC Linker
|
Cancer
|
|
Phe-Lys(Fmoc)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs) .
|
-
- HY-129360A
-
|
|
ADC Linker
|
Cancer
|
|
Ala-Ala-Asn-PAB TFA is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs) .
|
-
- HY-141862
-
|
|
Influenza Virus
|
Infection
|
|
Zanamivir–cholesterol conjugate is a long-acting neuraminidase inhibitor with potent efficacy against drug-resistant influenza viruses.
|
-
- HY-W190944
-
-
- HY-129349
-
|
|
ADC Linker
|
Cancer
|
|
Phe-Lys(Trt)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs) .
|
-
- HY-I0169
-
-
- HY-76772B
-
|
(-)-SNI-2011; (-)-AF102B hydrochloride hemihydrate
|
mAChR
|
Neurological Disease
|
|
(-)-Cevimeline hydrochloride hemihydrate ((-)-SNI-2011), a novel muscarinic receptor agonist, is a candidate therapeutic drug for xerostomia in Sjogren's syndrome.
|
-
- HY-158349
-
-
- HY-W038702
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-115127
-
|
|
Bacterial
|
Infection
|
|
3-Methylanisole is an intermediate in drug synthesis, which has antiseptic, antibacterial and protein stabilizing effects .
|
-
- HY-13995
-
|
|
FXR
Autophagy
|
Endocrinology
|
|
Sevelamer is a phosphate binding drug used to treat hyperphosphatemia in patients with chronic kidney disease; consists of polyallylamine that is crosslinked with epichlorohydrin.
|
-
- HY-121453
-
-
- HY-141664
-
|
|
ADC Linker
|
Cancer
|
|
PPA is an ADC linker (US20060073528A1). PPA can be used for making antibody-drug conjugate .
|
-
- HY-79129
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-D-Trp(Boc)-OH is a cleavable ADC linker that used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-16955
-
|
ACHN 490
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
|
|
Plazomicin (ACHN 490) is a potent aminoglycoside antibiotic in the fight against antimicrobial resistance. Plazomicin has in vitro activity against several multi-drug-resistant organisms, including carbapenem-resistant Enterobacteriaceae. Plazomicin has the potential to be used for multi-drug-resistant complicated urinary tract infections (cUTIs) or in combination for serious carbapenem-resistant Enterobacteriaceae infections .
|
-
- HY-160984
-
|
TEI 5103; TG 51
|
Others
|
Endocrinology
|
|
Rotraxate (TEI 5103) is an orally active anti-ulcer compound. Rotraxate can increase blood flow to the gastric mucosa and promote the integrity of the gastric mucosa. Rotraxate can be used to study the protective effects of drugs on the gastric mucosa, especially in investigating how drugs can prevent or treat gastric ulcers by acting directly on the gastric mucosa .
|
-
- HY-164309
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
DBCO-PEG3-Glu-Val-Cit-PABC-MMAE is a drug-linker conjugate for ADC. DBCO-PEG3-Glu-Val-Cit-PABC-MMAE contains a potent tubulin inhibitor Monomethyl auristatin E (MMAE, HY-15162) and can be used for synthesis of dual-drug ADC .
|
-
- HY-16955A
-
|
ACHN 490 sulfate
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
|
|
Plazomicin (ACHN 490) sulfate is a potent aminoglycoside antibiotic in the fight against antimicrobial resistance. Plazomicin sulfate is against several multi-drug-resistant organisms, including carbapenem-resistant Enterobacteriaceae. Plazomicin sulfate has the potential to be used for multi-drug-resistant complicated urinary tract infections (cUTIs) or in combination for serious carbapenem-resistant Enterobacteriaceae infections .
|
-
- HY-W009247S1
-
|
N-Demethylolanzapine-d8 hydrochloride; LY170055-d8 hydrochloride
|
Isotope-Labeled Compounds
|
Neurological Disease
|
|
N-Desmethylolanzapine-d8 hydrochloride (N-Demethylolanzapine-d8 hydrochloride) is the deuterium labeled N-Desmethylolanzapine (HY-W009247). N-Desmethylolanzapine is an antipsychotic drug. The formation of N-Desmethylolanzapine correlates with the level and activity of human liver flavin-containing monooxygenase (FMO3). N-Desmethylolanzapine can be used in the study of antipsychotic drugs .
|
-
- HY-144000A
-
|
|
Liposome
|
Others
|
|
DSPE-PEG2000-PDP is a phospholipid PEG conjugate that can be used in drug delivery applications .
|
-
- HY-140120
-
|
|
ADC Linker
|
Cancer
|
|
Mal-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-173633
-
|
|
ADC Linker
|
Cancer
|
|
BrAc-Val-Ala is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as ABBV-969 .
|
-
- HY-126353
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Val-Ala-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-44234
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Gly-Gly-Phe-OtBu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-153756
-
|
|
Prion Protein
|
Infection
|
|
GFP16 is a low affinity antiprion compound. GFP16 can be used for research of antiprion drug discovery .
|
-
- HY-B0735
-
-
- HY-140116
-
|
|
ADC Linker
|
Cancer
|
|
Boc-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-124329A
-
|
|
ADC Linker
|
Cancer
|
|
BS3 Crosslinker disodium is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130961
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Val-Dil-Dap-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-141145
-
|
|
ADC Linker
|
Cancer
|
|
OPSS-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-44222
-
|
|
ADC Linker
|
Cancer
|
|
MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-15029S
-
-
- HY-14398
-
|
SC 58635
|
COX
|
Inflammation/Immunology
Cancer
|
|
Celecoxib,a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC50 of 40 nM.
|
-
- HY-130932
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-160967
-
-
- HY-N10430
-
|
|
HIV
|
Infection
|
|
Patentiflorin A is a potent, broadspectrum HIV-1 inhibitor. Patentiflorin A also inhibits HIV drug-resistant strains .
|
-
- HY-400191A
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Gly-Gly-allyl propionate is a cleavable linker that can be used to synthesize Antibody-Drug Conjugates (ADCs) .
|
-
- HY-136136
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140118
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-156727
-
|
|
ADC Linker
|
Cancer
|
|
Val-Cit-PABC-Ahx-May is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-164731
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG12-DOTA is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W281713
-
|
Fluorescein chloride
|
Fluorescent Dye
|
Others
|
|
3,6-Dichlorofluorescein, a fluoresceina, can be used in the spot test for drugs containing amino and heterocyclic nitrogen .
|
-
- HY-131833
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-141144
-
|
|
ADC Linker
|
Cancer
|
|
OPSS-Val-Cit-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-126670
-
|
|
ADC Linker
|
Cancer
|
|
mDPR(Boc)-Val-Cit-PAB is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC) .
|
-
- HY-141142
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-139353
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Phe-Lys(Boc)-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140117
-
|
|
ADC Linker
|
Cancer
|
|
Boc-aminooxy-ethyl-SS-propanol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-131598
-
|
6-Thioguanosine-5'-triphosphate
|
Ras
|
Inflammation/Immunology
Cancer
|
|
6-Thio-GTP is an analogue of GTP, and a metabolite of an immunosuppressive drug, Azathioprine (HY-B0256) .
|
-
- HY-400191
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Gly-(d-Gly)-allyl propionate is a cleavable linker that can be used to synthesize Antibody-Drug Conjugates (ADCs).
|
-
- HY-130930
-
|
|
ADC Linker
|
Cancer
|
|
Acid-propionylamino-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-133007
-
|
|
Progesterone Receptor
|
Metabolic Disease
|
|
Algestone acetophenide is a progesterone drug. Algestone acetophenide can be used in combination with estrogen as a long-acting injectable contraceptive .
|
-
- HY-140125
-
|
|
ADC Linker
|
Cancer
|
|
2-Hydroxyethyl disulfide mono-tosylate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-123388
-
-
- HY-126497
-
|
|
ADC Linker
|
Cancer
|
|
LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs) .
|
-
- HY-136107
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Phe-Lys(Trt)-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-119211
-
-
- HY-137774
-
-
- HY-126663
-
|
|
ADC Cytotoxin
|
Cancer
|
|
N-Me-L-Ala-maytansinol is a hydrophobic, cell permeable payload used for making antibody-drug conjugate (ADC) .
|
-
- HY-135975
-
|
|
ADC Linker
|
Cancer
|
|
MC-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-114430
-
|
|
ADC Linker
|
Others
|
|
Fmoc-Phe-Lys(Boc)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-W071007
-
|
|
ADC Linker
|
Cancer
|
|
NO2-SPDMV is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-139856
-
|
|
ADC Linker
|
Cancer
|
|
Mal-Ala-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-137160
-
|
|
COX
|
Inflammation/Immunology
|
|
(±)-Ketoprofen glucuronide is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) Ketoprofen (HY-B0227) .
|
-
- HY-150220
-
|
|
Liposome
|
Others
|
|
1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate is a lipid used in the synthesis of phospholipid vesicles. 1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate works with other lipids to convert polydisperse vesicles into vesicles of uniform size by freeze-thaw and extrusion techniques. 1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate can enhance protein encapsulation efficiency for drug delivery and biochemical applications .
|
-
- HY-132254A
-
|
IMMU-132 (solution)
|
Antibody-Drug Conjugates (ADCs)
TROP2
|
Cancer
|
|
Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38. The antibody portion is Sacituzumab (HY-P99045), and the drug-linker conjugate for ADC is CL2A-SN-38 (HY-128946). Sacituzumab govitecan shows anticancer activity .
|
-
- HY-171265
-
|
|
Antibody-Drug Conjugates (ADCs)
EGFR
|
Others
|
|
MRG003 is an Antibody-Drug Conjugate (ADC) that consists of an anti-EGFR humanized IgG1 monoclonal antibody Becotatug (HY-P990049) and MMAE (HY-15162). These two parts are connected through a valine-citrulline (valine-citrulline) linker, where the linker and MMAE constitute the ADC's Drug-Linker conjugate VcMMAE (HY-15575) .
|
-
- HY-162613
-
|
|
Phospholipase
|
Neurological Disease
|
|
ASM-IN-2 (Compound 46) is a potent ASM inhibitor with an IC50 value of 0.87 μM, displaying good drug-like properties. ASM-IN-2 involves in multiple antidepressant mechanisms of actionin, which are associated with a decline of ceramide. It demostrates remarkable antidepressant effects in the CUMS-induced mouse, which is promising for research in the field of antidepressant drugs .
|
-
- HY-132254
-
|
IMMU-132
|
Antibody-Drug Conjugates (ADCs)
TROP2
|
Cancer
|
|
Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38. The antibody portion is Sacituzumab (HY-P99045), and the drug-linker conjugate for ADC is CL2A-SN-38 (HY-128946). Sacituzumab govitecan shows anticancer activity .
|
-
- HY-107468
-
|
|
HIV Protease
|
Infection
Inflammation/Immunology
|
|
PL-100 is a potent HIV-1 protease inhibitor with a Ki of 36 pM and an EC50 of 16 nM. PL-100 inhibits viral replication by suppressing HIV-1 protease activity and demonstrates excellent antiviral efficacy against drug-resistant HIV strains. PL-100 can be used in research on drug-resistant HIV disease .
|
-
- HY-131486
-
|
|
Nuclear Hormone Receptor 4A/NR4A
|
Cancer
|
|
Digoxigenin bisdigitoxoside is an anticancer agent and an active derivative of cardiac glycosides. Cardiac glycosides exert their apoptotic effects through the Nur77-dependent apoptotic pathway. Digoxigenin bisdigitoxoside is cytotoxic .
|
-
- HY-W067427
-
|
|
IKK
|
Cancer
|
|
BAY32-5915 is a potent IKKα inhibitor with an IC50 value of 60 nM. BAY32-5915 has not affect Doxorubicin (HY-15142A)-induced NF-κB activation .
|
-
- HY-111308
-
-
- HY-W048829
-
|
|
Amino Acid Derivatives
|
Others
|
|
Boc-Phe-Gly-OH is a Boc-protected phenylalanyl glycine derivative, can be used for the synthesis of agents or other compounds .
|
-
- HY-124919
-
|
|
AMPK
|
Metabolic Disease
|
|
JJO-1 is an AMPK activator with an EC50 of 1.8 μM. JJO-1 can be used in the study of obesity and type 2 diabetes .
|
-
- HY-163687
-
-
- HY-Y1093
-
|
Ethyl acetylacetate; EAA
|
Bacterial
Antibiotic
|
Infection
|
|
Ethyl acetoacetate (Ethyl acetylacetate) is an ester widely used as an intermediate in the synthesis of many varieties of compounds . Ethyl acetoacetate is an inhibitor of bacterial biofilm .
|
-
- HY-101427
-
-
- HY-105855
-
-
- HY-148407
-
|
|
Fluorescent Dye
|
Others
|
|
lucPpy-IN-1 (compound 9) is an ATP-dependent luciferase from Photinus pyralis (lucPpy) inhibitor with an IC50 value of 4.0 μM. lucPpy-IN-1 can be used for the research of target’s agentgability .
|
-
- HY-105710
-
|
|
Cholinesterase (ChE)
|
Neurological Disease
|
|
Tropatepine is an orally active, anticholinergic muscarinic antagonist and can be used as an antiparkinsonian agent . Tropatepine is used to combat against extrapyramidal syndrome induced by neuroleptic agents .
|
-
- HY-116610
-
|
|
COX
|
Inflammation/Immunology
|
|
L 748780 (compound 2) is a selectivity COX-2 inhibitor with the IC50 values of 0.5 μM and ＞ 100 μM for COX-2 and COX-1, respectively .
|
-
- HY-132031
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Mal-Val-Ala-PAB(C2-glucuronic acid)-DMEA-PNU-159682 is an active molecule-conjugate for ADCs, composed of a cleavable Val-Ala linker and the potent ADC cytotoxic payload PNU-159682 (HY-16700) .
|
-
- HY-W715783
-
|
Divaric acid; Divarinolic acid; Varinolic acid
|
Biochemical Assay Reagents
|
Others
|
|
Divarinic acid (also known as Divaric acid, Divarinolic acid, or Varinolic acid) serves as an intermediate in the biosynthetic pathway of phytocannabinoids, and can be used to synthesize the cannabinoid precursor CBGVA .
|
-
- HY-16569R
-
|
|
Reference Standards
Microtubule/Tubulin
NOD-like Receptor (NLR)
Autophagy
Apoptosis
|
Cancer
|
|
Colchicine (Standard) is the analytical standard of Colchicine. This product is intended for research and analytical applications. Colchicine, an orally active alkaloid, is a potent tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs). Colchicine prevents non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome. Colchicine has extensive anti-inflammatory, immunosuppressive and strong anti-fibrosis effects and has the potential for gouty arthritis research .
|
-
- HY-131451
-
-
- HY-165512
-
|
|
LDLR
|
Cardiovascular Disease
|
|
Nicanartine, an orally active antioxidant and lipid-lowering compound, is an antiatherogenic drug. Nicanartine inhibits the oxidation of low-density lipoprotein (LDL).
|
-
- HY-130956
-
|
|
ADC Linker
|
Cancer
|
|
Boc-NMe-Val-Val-Dil-Dap-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-W040236
-
-
- HY-130090
-
|
|
ADC Linker
|
Cancer
|
|
NHPI-PEG4-C2-Pfp ester is used as a linker for antibody-drug conjugates (ADC).
|
-
- HY-133547
-
|
|
ADC Linker
|
Cancer
|
|
NO2-SPP-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-B0937A
-
|
|
Parasite
|
Infection
|
|
Amprolium hydrochloride is an anti-parasitic drug that's kind of taken orally, and it acts as an antagonist to thiamine in intestinal absorption .
|
-
- HY-164759
-
|
|
NAMPT
|
Cancer
|
|
Nampt-IN-13 (example 58m) is a NAMPT inhibitor that can be used in the synthesis of Antibody-drug Conjugate (ADC) .
|
-
- HY-133548
-
|
|
ADC Linker
|
Cancer
|
|
NO2-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-78921
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130976
-
|
|
ADC Linker
|
Cancer
|
|
N-Boc-Val-Dil-Dap-Doe is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-136132
-
|
|
ADC Linker
|
Cancer
|
|
MC-VC-PAB-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-101993
-
|
|
Amino Acid Derivatives
|
Others
|
|
Nap-FF is a cell-penetrating dipeptide that can be used in the preparation of hydrogel chemosensors and in the research of targeted drug delivery .
|
-
- HY-N12038
-
-
- HY-136547
-
|
|
ADC Linker
|
Others
|
|
Boc-Val-Ala-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate (ADCs) .
|
-
- HY-129350
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Phe-Lys(Trt)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130547
-
|
|
ADC Linker
|
Cancer
|
|
BS2G Crosslinker (disodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-129378
-
|
|
ADC Linker
|
Cancer
|
|
NO2-SPP-sulfo-Me is a cleavable linker that is used for making antibody-drug conjugate (ADC) .
|
-
- HY-156727A
-
|
|
ADC Linker
|
Cancer
|
|
Val-Cit-PABC-Ahx-May TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-126533
-
|
|
ADC Linker
|
Cancer
|
|
PDP-C1-Ph-Val-Cit is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
|
-
- HY-133549
-
|
|
ADC Linker
|
Cancer
|
|
NO2-SPDMV-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-B1054
-
|
|
COX
|
Inflammation/Immunology
|
|
Famprofazone is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the pyrazolone series, and it has analgesic, anti-inflammatory, and antipyretic effects.
|
-
- HY-120903
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-C3-Acid is a Click Chemistry intermediate used in the synthesis of antibody-drug conjugate (ADC) linker .
|
-
- HY-130975
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Val-Dil-Dap-Phe-OMe is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130098
-
|
|
ADC Linker
|
Cancer
|
|
Ald-Ph-amido-PEG3-C-COOH is a noncleavable linker used for the antibody-drug conjugate (ADC).
|
-
- HY-16372
-
-
- HY-135624
-
|
|
Endogenous Metabolite
|
Others
|
|
Neogen, also referred to as Jadinol PU, is a promising drug designed to aid in the restoration of the immune system and hemopoiesis following treatment with cytostatics.
|
-
- HY-W1048828E
-
-
- HY-117065
-
|
|
Bacterial
|
Infection
|
|
MAC173979 is a inhibitor of PABA synthesis in E. coli. MAC173979 can be used for study of antibacterial drug development .
|
-
- HY-W888521
-
-
- HY-140119
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-NH-ethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-106472
-
|
EMD 26644
|
Bacterial
|
Infection
|
|
Tioxaprofen is a new anti-mycotic drug against Trichophyton mentagrophytes and T. rubrum, and is a potent uncoupling agent of mitochondrial respiration .
|
-
- HY-132251
-
|
|
ADC Linker
|
Cancer
|
|
MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1 .
|
-
- HY-18706
-
-
- HY-W011561
-
|
|
ADC Linker
|
Cancer
|
|
Boc-NH-C6-Br is a non-cleavable linker used for antibody-drug conjugates (ADC) .
|
-
- HY-130933
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Ala-Ala-Asn(Trt)-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-126502
-
|
|
ADC Linker
|
Cancer
|
|
Mal-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-136329
-
|
|
ADC Linker
|
Cancer
|
|
β-D-glucuronide-pNP-carbonate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W250574
-
-
- HY-164928
-
|
|
ADC Linker
|
Others
|
|
PTAD-PEG8-alkyne is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W419044A
-
|
|
Fluorescent Dye
|
Others
|
|
Calcein calcium potassium is the calcium potassium salt form of Calcein (HY-D0040). Calcein calcium potassium is a fluorescent dye and self-quenching probe, that can used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein calcium potassium can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems .
|
-
- HY-W130354
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cucurbituril is a container molecule resembling a hollow pumpkin, with two identical inlets at each end and a hydrophobic cavity in the middle. Cucurbiturils have unique chemical properties that allow them to selectively encapsulate guest molecules such as drugs or catalysts within their cavities, shielding them from the surrounding environment. Cucurbituril has important potential applications in various fields such as drug delivery, catalysis and materials science.
|
-
- HY-B0276A
-
|
2-Ethylthioisonicotinamide hydrochloride
|
Bacterial
|
Infection
|
|
Ethionamide hydrochloride (2-Ethylthioisonicotinamide hydrochloride) is an antituberculosis drug with mycobacterial activity. Ethionamide hydrochloride interferes with the bacterial cell wall synthesis process by inhibiting the synthesis of fatty acids in the bacterial cell wall. Ethionamide hydrochloride may have bacteriostatic or bactericidal effects, depending on the concentration of the drug at the site of infection and the susceptibility of the associated microorganisms. Ethionamide hydrochloride combines with NAD+ to form an adduct, thereby exerting its antibacterial effect .
|
-
- HY-144880
-
|
3-Aminophenyl Hemiasterlin
|
ADC Cytotoxin
Microtubule/Tubulin
P-glycoprotein
|
Cancer
|
|
SC209 (3-Aminophenyl Hemiasterlin) is a 3-aminophenyl hemiasterlin derivative that serves as a cytotoxin for ADCs, targeting tubulin. SC209 has reduced potential for drug efflux via P-glycoprotein 1 drug pump compared with other tubulin-targeting payloads. SC209 exhibits antitumor activity and can be used in the synthesis of ADC molecules .
|
-
- HY-149346
-
|
|
Bacterial
|
Infection
|
|
Mtb-IN-2 (compound 10c) is an antimicrobial agent against Mycobacterium tuberculosis (Mtb), without cytotoxicity. Mtb-IN-2 significantly decreases colony-forming units (CFU) in spleen of murine tuberculosis models, and distinguishes both drug-sensitive and drug-resistant Mtb H37Rv strains. Mtb-IN-2 affects methionine metabolism but not folate pathway directly.
|
-
- HY-141143
-
|
|
ADC Linker
|
Cancer
|
|
MC(C5)-Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-129351
-
|
|
ADC Linker
|
Cancer
|
|
Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-136132A
-
|
|
ADC Linker
|
Cancer
|
|
MC-VC-PAB-NH2 TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-142025
-
|
|
Others
|
Infection
Metabolic Disease
|
|
Daumone is a natural product secreted by Caenorhabditis elegans. Daumone can be used for aging and obesity research and the development of anti-nematode drugs .
|
-
- HY-B1542
-
|
|
Cholinesterase (ChE)
|
Neurological Disease
|
|
Benactyzine is a competitive BChE inhibitor with a Ki of 0.01 mM. Benactyzine is an anticholinergic drug. Benactyzine has the potential for organophosphate poisoning research .
|
-
- HY-W087028
-
-
- HY-78921AG
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-3VVD-OH (GMP) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-136154
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Glu-(Boc)-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-145488
-
|
|
ADC Linker
|
Cancer
|
|
MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-138651
-
|
|
ADC Linker
|
Inflammation/Immunology
|
|
PAB-Val-Lys-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) for stimulating an immune response .
|
-
- HY-12385
-
|
|
TNF Receptor
|
Inflammation/Immunology
|
|
Ximoprofen is a propionic nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory property. Ximoprofen can be used for ankylosing spondylitis research .
|
-
- HY-156507
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-PEG3-NHS ester (cpmpd 45) is a ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-B1542A
-
|
|
Cholinesterase (ChE)
|
Neurological Disease
|
|
Benactyzine hydrochloride is a competitive BChE inhibitor with a Ki of 0.01 mM. Benactyzine hydrochloride is an anticholinergic drug. Benactyzine hydrochloride has the potential for organophosphate poisoning research .
|
-
- HY-158348
-
-
- HY-160703
-
|
|
Drug Intermediate
|
Cancer
|
|
DMBA-SIL-PNP (Compound 5) is an intermediate used for preparing Drug-Linker Conjugates, which can be applied in cancer research .
|
-
- HY-N13147
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Tetromycin C5 is an antibiotic, that exhibits board-spectrum antibacterial activity against gram-positive bacteria and their drug-resistant bacteria .
|
-
- HY-12651B
-
|
|
Endogenous Metabolite
|
Infection
|
|
l-Primaquine is an antimalarial drug with activity in inhibiting and preventing malaria. l-Primaquine is also used to inhibit Pneumocystis jiroveci pneumonia .
|
-
- HY-164707
-
-
- HY-133584
-
|
|
ADC Linker
|
Cancer
|
|
Bis-SS-C3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W354479
-
|
Thioinosinic acid
|
Drug Metabolite
|
Inflammation/Immunology
|
|
6-Thioinosine Phosphate (Thioinosinic acid) is an intermediate metabolite of azathioprine (HY-B0256). Azathioprine is a purine analog immunosuppressive drug .
|
-
- HY-124351
-
|
|
COX
|
Inflammation/Immunology
|
|
5'-Hydroxy meloxicam is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) Meloxicam (HY-B0261) .
|
-
- HY-164705
-
-
- HY-17579
-
-
- HY-400356
-
|
|
ADC Linker
|
Cancer
|
|
Glucocorticoid receptor agonist-1 phosphate Gly-Glu (TFA) is a cleavable linker, that can be used to synthesize Antibody-Drug Conjugates (ADCs).
|
-
- HY-W004564
-
-
- HY-140126
-
|
|
ADC Linker
|
Cancer
|
|
Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-112111
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
Poly-L-Glutamic acid (MW 700000) is biochemical reagent.Poly-L-Glutamic acid can be used as the drug carrier for targeted delivery of anticancer agents .
|
-
- HY-Y0267
-
|
|
Insecticide
Fungal
Phytohormone
|
Infection
|
|
Phenoxyacetic acid is a multifunctional drug prodrug or auxin-type growth regulator, and its derivatives have insecticidal, herbicidal and antifungal activities .
|
-
- HY-44980
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Gly-NH-CH2-acetyloxy is a cleavable linker that can be used to synthesize antiboy-drug Conjugates (ADCs).
|
-
- HY-W005176
-
|
Methyl Butyrylacetate; Methyl 3-oxohexanoate
|
Biochemical Assay Reagents
|
Others
|
|
Methyl 3-oxohexanoate (Methyl Butyrylacetate) is an organic compound commonly used in the manufacture of fragrances, drugs, and other chemicals. It can be used as a condensation reagent, a diazotization reagent and an addition reagent, and it plays a catalytic role in some organic synthesis reactions, and can also play a role in some drug synthesis. In addition, the compound is widely used in the food industry, for example in products such as juices, beer and confectionery.
|
-
- HY-164310
-
|
|
Microtubule/Tubulin
Drug-Linker Conjugates for ADC
|
Cancer
|
|
TCO-PEG3-Glu-Val-Cit-PABC-MMAF is a linker-drug conjugate, which is consisted of a click pair TCO, a spacer PEG, a cleavable linker Glu-Val-Cit, a PBAC group and a cytotoxin MMAF (HY-15579). TCO-PEG3-Glu-Val-Cit-PABC-MMAF can be used for synthesis of dual drug ADC .
|
-
- HY-P9985
-
|
RC48
|
Antibody-Drug Conjugates (ADCs)
EGFR
|
Cancer
|
|
Disitamab vedotin (RC48) is an antibody-drug conjugate (ADC) comprising a monoclonal antibody against human epidermal growth factor receptor 2 (HER2) conjugated via a cleavable linker to the cytotoxic agent Monomethyl auristatin E (MMAE) (HY-15162), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E). Disitamab vedotin enhances antitumor immunity .
|
-
- HY-W440883
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Ald, MW 2000 is a phospholipid polyPEG which can self-assemble to form lipid bilayer in aqueous solution. The polymer can be used to prepare liposome as a drug delivery vehicle for administration of drugs or nutrients, such as mRNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
-
- HY-141147
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
7-O-(Amino-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Amino-PEG4)-paclitaxel can be used in the synthesis of Antibody-Drug Conjugates (ADCs) .
|
-
- HY-P9921
-
|
Ado-Trastuzumab emtansine; PRO132365; T-DM 1
|
Antibody-Drug Conjugates (ADCs)
EGFR
|
Cancer
|
|
Trastuzumab emtansine (Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that incorporates the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1 (derivative of maytansine), and the drug-linker conjugate for ADC is SMCC-DM1 (HY-101070). Trastuzumab emtansine can be used for the research of advanced breast cancer .
|
-
- HY-P9921A
-
|
Ado-Trastuzumab emtansine (solution); PRO132365 (solution); T-DM 1 (solution)
|
Antibody-Drug Conjugates (ADCs)
EGFR
|
Cancer
|
|
Trastuzumab emtansine (Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that incorporates the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1 (derivative of maytansine), and the drug-linker conjugate for ADC is SMCC-DM1 (HY-101070). Trastuzumab emtansine can be used for the research of advanced breast cancer .
|
-
- HY-N0283
-
|
Diacerhein; Diacetylrhein
|
Interleukin Related
Calcium Channel
|
Inflammation/Immunology
|
|
Diacerein (Diacerhein), an orally active anthraquinone, reduces production of IL-1 converting enzyme then inhibits the activation of IL-1β by related downstream signaling. Diacerein is an anti-inflammatory and anti-rheumatic drug. Diacerein can relieve bronchospasm and control airway inflammation in asthmatic mice. Diacerein has the potential for slow acting drug in osteoarthritis (SYSADOA) research .
|
-
- HY-W087964
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dodecanedioyl dichloride, Dodecanedioyl dichloride is commonly used in organic synthesis as a general building block for the preparation of various polymers and plastics, including nylon 12 and polyester resins, it can be used to introduce acid chloride groups into other organic molecules, which can then be further reaction to form more complex compounds, moreover, it has been used in medicinal chemistry as a starting material for the synthesis of various drugs and drug candidates.
|
-
- HY-16387
-
|
|
VEGFR
|
Others
|
|
PF-00337210 is a potent and selective inhibitor of VEGFRs, designed for treating age-related macular degeneration via intravitreal injection. The formulation strategy focused on developing an ophthalmic solution that would precipitate upon injection into the vitreous, ensuring sustained drug delivery. Challenges included maintaining low dosing volumes, selecting safe excipients for intravitreal use, and addressing the drug's unique physicochemical properties. The final formulation, an isotonic solution in a citrate-buffered vehicle with NaCl, demonstrated stability, potency, and recovery through intravitreal dosing syringes. It formed a depot upon injection into vitreous humor, representing a novel nonpolymeric in situ-forming depot formulation for intravitreal drug delivery .
|
-
- HY-112624E
-
|
Dextran 0.8; Dextran D0.8; Dextran T0.8(MW 640-960)
|
Biochemical Assay Reagents
|
Others
|
|
Dextran T0.8 (Dextran 0.8; Dextran T0.8(MW 640-960)) is a food additive with a porous network structure that exhibits strong hydration capacity and low browning activity. Dextran T0.8 (MW 800) can improve the coagulation of dairy products and is used as a prebiotic in baked goods. Dextran T0.8 (MW 800) is non-toxic to HeLa cells at a concentration of ~500 μg/mL and has a low relative browning rate in the Maillard reaction. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
|
-
- HY-112624J
-
|
Dextran 4; Dextran D4; Dextran T4(MW 3200-4800)
|
Bacterial
|
Others
|
|
Dextran 4,000 is a mucus rheology modifier. The dextran molecules in Dextran 4,000 can reduce the cross-link density of mucus through osmotic effects and hydrogen bond substitution, and reduce viscoelasticity and improve the mucociliary/cough clearance index by destroying the DNA-mucin network structure in mucus. Dextran 4,000 has the ability to improve the rheological properties and clearance ability of cystic fibrosis (CF) sputum, and can be used in the study of inhalation therapy or aerosol delivery of mucostatic respiratory diseases. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
|
-
- HY-W250410
-
|
|
ADC Linker
|
Cancer
|
|
N-Methyl-N-[(3-methyldithio)-1-oxopropyl]-L-alanine is a PEGn linker for antibody-drug-conjugation (ADC).
|
-
![N-Methyl-N-[(3-methyldithio)-1-oxopropyl]-L-alanine](//file.medchemexpress.com/product_pic/hy-w250410.gif)
- HY-W105531
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Ala-Ala-Pro-OH is a F-moc protected tripeptide linker which may be employed in the creation of antibody drug conjugates (ADCs).
|
-
- HY-N8763
-
|
Guaianin A
|
Others
|
Neurological Disease
|
|
Ciwujianoside E is a triterpene saponin that can be isolated from Acanthopanax senticosus. Ciwujianoside E can be used in study sedative-hypnotic drug .
|
-
- HY-141355
-
|
|
ADC Linker
|
Cancer
|
|
OPSS-PEG36-acid is a cleavable 36 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-13677
-
-
- HY-W725745
-
|
1,3,5-Tris(6-isocyanatohexyl)-1,3,5-triazinane-2,4,6-trione
|
Biochemical Assay Reagents
|
Others
|
|
Tris(6-isocyanatohexyl)isocyanurate is a cross-linking agent that can be used for the research of novel drug-carrying matrix systems .
|
-
- HY-157275
-
|
|
ADC Linker
|
Cancer
|
|
Gly-Gly-Gly-PEG2-azide is an ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130097
-
|
|
ADC Linker
|
Cancer
|
|
Ald-Ph-amido-PEG4-C2-acid is a noncleavable linker used for the antibody-drug conjugate (ADC).
|
-
- HY-145489
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG2-Val-Cit-PABA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-136106
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Gly3-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-172356A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG-NH2 (Mn 5300) can be used for biotinylation of polymerized worm micelles for targeting and drug transfer to cells .
|
-
- HY-122073
-
|
|
Bacterial
|
Infection
|
|
Furalazine is an antimicrobial agent. Furalazine shows activity against drug-resistant strains of cholera bacteria. Furalazine has the potential for the research of cholera .
|
-
- HY-148550
-
|
|
ADC Linker
|
Cancer
|
|
MC-PEG2-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-141123
-
|
|
ADC Linker
|
Cancer
|
|
SPDP-C6-Gly-Leu-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-144630
-
-
- HY-133408
-
|
|
ADC Linker
|
Cancer
|
|
4-Methyl-4-(methyldisulfanyl)pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-144629
-
-
- HY-173161
-
|
|
ADC Linker
|
Cancer
|
|
Mc-d-Val-d-Cit-PAB-PNP is a cleavable ADC linker that can be used for synthesizing antibody-drug conjugates (ADCs) .
|
-
- HY-133585
-
|
|
ADC Linker
|
Cancer
|
|
Bis-SS-C3-sulfo-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-145367
-
|
|
ADC Linker
|
Cancer
|
|
Ala-CO-amide-C4-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-16672
-
|
|
Bacterial
|
Infection
|
|
AVX 13616 shows the potent in vivo antibacterial activity of Avexa’s lead antibacterial candidate; particularly against drug-resistant Staphylococcus pathogens.
|
-
- HY-172356
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG-NH2 (Mn 3700) can be used for biotinylation of polymerized worm micelles for targeting and drug transfer to cells .
|
-
- HY-141353
-
|
|
ADC Linker
|
Cancer
|
|
SPDP-PEG12-acid is a cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-145148
-
|
|
ADC Cytotoxin
|
Cancer
|
|
Hemiasterlin derivative-1 is a hemiasterlin derivative. Hemiasterlin derivative-1 can be used for the synthesis of the antibody-drug conjugate (ADC) .
|
-
- HY-102001
-
|
|
ADC Cytotoxin
|
Cancer
|
|
Tomaymycin DM, a DNA alkylator, is a derivative of Tomaymycin, it is a PBD dimer, which is attached to tumor targeting antibodies to create antibody-drug conjugates (ADCs).
|
-
- HY-129909
-
|
|
Apoptosis
|
Infection
Cancer
|
|
Anticancer agent 173 (compound 19) is a potent thioxodihydroquinazolinone analogs when combined with platinum drugs in inducing apoptotic cancer cells death .
|
-
- HY-B1620H
-
|
PVP K90; Polyvidone K90; Povidone K90
|
Biochemical Assay Reagents
|
Infection
|
|
Polyvinylpyrrolidone K90 can be used to prepare drug delivery systems, such as electrospun nanofibrous membranes. Polyvinylpyrrolidone K90 is widely used in human and veterinary medicine as an effective wound healing promoter and disinfectant when combined with iodine and other compounds. In addition, Polyvinylpyrrolidone K90 is also used to stabilize nanosuspensions, interact with the surface of drug crystals, and remain bound to the surface after drying .
|
-
- HY-D2431
-
|
|
Fluorescent Dye
|
Others
|
|
Galactose-PEG-Cy3 is a Cy3 (HY-D0822) labeled Galactose-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Galactose-PEG improves drug cellular uptake and reduces endosomal degradation, and can be used in drug delivery .
|
-
- HY-112490
-
|
|
HMG-CoA Reductase (HMGCR)
|
Cardiovascular Disease
Others
|
|
Atorvastatin calcium salt trihydrate is a drug belonging to the statin class of drugs used to lower blood cholesterol levels. Atorvastatin calcium salt trihydrate has unique chemical properties that make it an effective tool in controlling high levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the body, reducing the risk of heart attack and stroke. Atorvastatin calcium salt trihydrate works by inhibiting HMG-CoA reductase, the enzyme responsible for producing cholesterol in the liver.
|
-
- HY-B0067B
-
|
(R)-SM-5887
|
Topoisomerase
|
Cancer
|
|
(R)-Amrubicin ((R)-SM-5887) is an anthracycline that effectively treats lung cancer by intercalating into DNA and inhibiting topoisomerase II activity, which consequently hampers DNA replication as well as RNA and protein synthesis, leading to cell growth inhibition and apoptosis. This compound exhibits superior anti-tumor efficacy compared to traditional anthracycline drugs while lacking the cumulative cardiac toxicity typically associated with this drug class.
|
-
- HY-129311
-
-
- HY-136051
-
|
|
ADC Linker
|
Cancer
|
|
Biotin-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-141594
-
|
|
Microtubule/Tubulin
|
Cancer
|
|
Modified MMAF, an ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). Modified MMAF can be used for the targeted research of cancer .
|
-
- HY-131156
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG2-Val-Cit-PABA-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-136309
-
|
|
ADC Linker
|
Cancer
|
|
Ald-PEG23-SPDP is a cleavable 23 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-133050
-
|
|
ADC Linker
|
Cancer
|
|
Hydroxy-PEG6-acid is a PEG-based non-cleavable ADC linker that can be used in the synthesis of Antibody-Drug Conjugates (ADCs) .
|
-
- HY-140115
-
|
|
ADC Linker
|
Cancer
|
|
Bis-(PEG6-acid)-SS is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W352966
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG2-CH2COOH is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-138484
-
|
|
ADC Linker
|
Cancer
|
|
Folate-PEG3-amine is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-135961
-
|
|
ADC Linker
|
Cancer
|
|
PTAD-PEG4-amine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-148461
-
|
|
ADC Linker
|
Cancer
|
|
Mal-VC-PAB-PNP is a cleavable ADC linker. Mal-VC-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-116655
-
|
|
ADC Linker
|
Cancer
|
|
Hydroxy-PEG1-acid is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-135974
-
|
|
ADC Linker
|
Cancer
|
|
Amino-PEG3-SS-acid is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-148463
-
|
|
ADC Linker
|
Cancer
|
|
MP-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-131086
-
-
- HY-126883
-
-
- HY-135125
-
|
|
ADC Cytotoxin
|
Cancer
|
|
DC4, an ADC cytotoxin, can be used in the synthesis of antibody-drug conjugate (ADC). DC4 can be used for the targeted treatment of cancer .
|
-
- HY-133544
-
|
|
ADC Linker
|
Cancer
|
|
Mal-CO-PEG5- NHS ester is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-140244
-
|
|
ADC Linker
|
Cancer
|
|
Gly-PEG3-amine is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-148462
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-B0106A
-
|
UCB 6474
|
Calcium Channel
|
Neurological Disease
|
|
Etiracetam (UCB 6474) is an acetylcholine agonist and a nootropic drug of the racetam family. Less active than its S-enantiomer Levetiracetam (UCB L059) .
|
-
- HY-140144
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG1-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-41049
-
|
|
ADC Linker
|
Cancer
|
|
NSC 135130 (compound 11a) is a BOC-protected ADC linker that can be linked to tubulin-targeting inhibitors.Can be used to synthesize drug conjugates .
|
-
- HY-148464
-
|
|
ADC Linker
|
Cancer
|
|
MC-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140097
-
|
|
ADC Linker
|
Cancer
|
|
Amino-SS-PEG12-acid is a cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-136048
-
|
|
ADC Linker
|
Cancer
|
|
Methylcyclopropene-PEG4-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-136127
-
|
|
ADC Linker
|
Cancer
|
|
ALD-PEG4-OPFP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-138488
-
|
|
ADC Linker
|
Cancer
|
|
Biotin-PEG4-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-136432
-
|
Mc-GGFG-PAB-OH
|
ADC Linker
|
Cancer
|
|
Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
|
-
- HY-153032
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Val-Ala-PAB-MMAE is a Drug-Linker Conjugate for ADC, consisting of ADC linker (Val-Ala-PAB) and MMAE. MMAE is an effective inhibitor of tubulin.
|
-
- HY-135964
-
|
|
ADC Linker
|
Cancer
|
|
(2-pyridyldithio)-PEG4 acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-170749
-
|
|
Drug Intermediate
|
Others
|
|
DFO-BCN is a drug intermediate, that can be used for synthesis of PET/CT imaging agent DFO-CPC634 through click chemistry .
|
-
- HY-136047
-
|
|
ADC Linker
|
Cancer
|
|
Methylcyclopropene-PEG3-amine is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-157338
-
|
|
ADC Linker
Kinesin
|
Cancer
|
|
NHS-Ala-Ala-Asn-active metabolite is a cleavable antibody-drug conjugate (ADC) linker for synthesis of kinesin spindle protein (KSP)inhibitor .
|
-
- HY-141358
-
|
|
ADC Linker
|
Cancer
|
|
SPDP-PEG36-NHS ester is a cleavable 36 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-141153
-
|
|
ADC Linker
|
Cancer
|
|
Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP is a cleavable linker for synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-123331
-
|
|
Parasite
|
Infection
|
|
S 82-5455 is a floxacrine derivative that exhibits high activity against drug-susceptible strains of Plasmodium berghei induced in mouse and rat blood .
|
-
- HY-12718A
-
|
|
Adrenergic Receptor
|
Endocrinology
|
|
(±)-WB 4101 is a potent antagonist of noradrenaline. (±)-WB 4101 interacts with protein in smooth muscle. (±)-WB 4101 makes drug and receptor bind tightly .
|
-
- HY-48668
-
|
|
ADC Linker
|
Cancer
|
|
AcLys-PABC-VC-Aur0101 intermediate-1 is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate .
|
-
- HY-W190927
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
MC-Val-Cit-Doxorubicin is drug-linker conjugate for ADC. The maleimide can conjugate with thiol containing molecules. Doxorubicin is an anthracycline antibiotic with antineoplastic activity
|
-
- HY-132163
-
|
|
ADC Linker
|
Cancer
|
|
MP-PEG4-VK(Boc)G-OSu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-120258
-
-
- HY-D2841
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-Heparin is a fluorescent dye composed of FITC (HY-66019) and Heparin. FITC-Heparin can be used for cell tracing and drug delivery .
|
-
- HY-B1346R
-
|
(±)-Glutamine (Standard); DL-Gl (Standard)
|
Reference Standards
Ferroptosis
Endogenous Metabolite
|
Others
|
|
DL-Glutamine (Standard) is the analytical standard for DL-Glutamine. This product is intended for research and analytical applications. DL-Glutamine is used for biochemical research and drug synthesis.
|
-
- HY-W008216
-
|
Hydroxy Dimetridazole
|
Drug Metabolite
Parasite
|
Infection
|
|
HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole (HY-B1244). Dimetridazole is a nitroimidazole class drug that combats protozoan infections .
|
-
- HY-132086
-
|
|
ADC Linker
|
Cancer
|
|
2-Pyridyldithio-PEG6 acid is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W019793
-
-
- HY-W047156
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
Allantoxanamide is a uricase inhibitor. Allantoxanamide-induced rats serve as animal models for studying purine biosynthesis, drug-induced hyperuricemia and hyperuricosuria, and related nephropathy .
|
-
- HY-D2433
-
|
|
Fluorescent Dye
|
Others
|
|
Glucose-PEG2000-Cy3 is a Cy3 (HY-D0822) labeled Glucose-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Glucose-PEG improves drug cellular uptake and reduces endosomal degradation, and can be used in drug delivery .
|
-
- HY-162508
-
|
|
Bacterial
|
Infection
|
|
KSK-104 has potent antibacterial activity against Mycobacterium tuberculosis (MIC=0.78 μM). The role of KSK-104 is mainly involved in the synthesis and recovery pathways of pyridoxal 5'-phosphate (PLP), PLP-dependent enzymes and oxidative stress networks. KSK-104, as a candidate molecule for novel anti-tuberculosis drugs, can be used to develop research against drug-resistant mycobacterium tuberculosis .
|
-
- HY-141148
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
7-O-(Cbz-N-amido-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Cbz-N-amido-PEG4)-paclitaxel can be used in the synthesis of Antibody-Drug Conjugates (ADCs) .
|
-
- HY-153600
-
-
- HY-136432A
-
|
Mc-GGFG-PAB-OH TFA
|
ADC Linker
|
Cancer
|
|
Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
|
-
- HY-P1449
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
|
-
- HY-169782
-
|
|
P-glycoprotein
|
Neurological Disease
|
|
CJZ3 is an reversible inhibitor for P-glycoprotein (P-gp), that accumulates the drug (Rh123) in cells, and improve the permeability of the blood-brain barrier (BBB) .
|
-
- HY-W800847
-
|
|
ADC Linker
|
Cancer
|
|
Mal-Amide-PEG4-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-133545
-
|
|
ADC Linker
|
Cancer
|
|
Mal-Ph-CONH-PEG4- NHS ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-135962
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Aminooxy-PEG2-bromide is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140124
-
|
|
ADC Linker
|
Cancer
|
|
THP-SS-PEG1-Tos is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-171114
-
|
|
Liposome
|
Others
|
|
DMT7 is an ionizable cationic lipid (pKa = 6.5) that can be used to generate lipid nanoparticles (LNPs) for delivery of mRNA and anticancer drugs in the body .
|
-
- HY-136041
-
|
|
ADC Linker
|
Cancer
|
|
Boc-amino-PEG3-SSPy is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140123
-
|
|
ADC Linker
|
Cancer
|
|
THP-SS-PEG1-Boc is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-128959
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
MCC-Modified Daunorubicinol is a drug-Linker conjugates for ADC, which is composed of Modified Daunorubicinol (DNA topoisomerase II inhibitor) and MCC (ADC linker) linked .
|
-
- HY-112561
-
-
- HY-157079
-
-
- HY-140134
-
|
|
ADC Linker
|
Cancer
|
|
PC Biotin-PEG3-NHS ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-148425
-
|
|
ADC Linker
|
Cancer
|
|
Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-151102
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Fabimycin is a FabI inhibitor with potent antibacterial activity against gram-negative bacteria. Fabimycin is effective against drug-resistant gram-negative Infections in vivo .
|
-
- HY-W011556
-
|
TCFH
|
Biochemical Assay Reagents
|
Others
|
|
N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate is a kind of biological coupling reagent, can be used for antitumor drugs sulphur alkali before medicine research .
|
-
- HY-139863
-
|
|
Bacterial
|
Infection
|
|
Antibacterial agent 62 is a novel redox cycling antituberculosis chemotype with potent bactericidal activity against growing and nutrient-starved phenotypically drug-resistant nongrowing bacteria.
|
-
- HY-170032
-
|
|
mAChR
|
Neurological Disease
|
|
Oxotremorine is an agonist for mAChR, that activates M1 and M3 acetylcholine receptors. Oxotremorine exhibits nicotine-like effects in drug discrimination experiments in macaques .
|
-
- HY-136097
-
|
|
ADC Linker
|
Cancer
|
|
Maleimide-PEG2-hydrazide (TFA) is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-129976
-
|
|
Endogenous Metabolite
|
Cancer
|
|
Pemetrexed tromethamine dihydrochloric dihydrate is a chemotherapy drug used to treat pleural mesothelioma and non-small cell lung cancer, exhibiting potent anti-cancer activity.
|
-
- HY-158351
-
-
- HY-135423
-
|
Dy-DTPA-BMA
|
Biochemical Assay Reagents
|
Others
|
|
Sprodiamide (Dy-DTPA-BMA) is a susceptibility-based MRI contrast agent that can be used to visualize image intensity changes during vascular transport of drugs .
|
-
- HY-150074
-
|
|
ADC Cytotoxin
|
Cancer
|
|
STING agonist-18 (compound 1a) can be used for synthesis of antibody-drug conjugates (ADCs), such Trastuzumab (HY-P9907) conjugate .
|
-
- HY-B0270R
-
|
TN-762 (Standard)
|
Reference Standards
PGE synthase
|
Inflammation/Immunology
|
|
Suprofen (Standard) is the analytical standard of Suprofen. This product is intended for research and analytical applications. Suprofen (TN-762) is a non-steroidal anti-inflammatory drug (NSAID).
|
-
- HY-P10027
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Clovibactin is an antibiotic for drug-resistant bacterial pathogens without detectable resistance. Clovibactin TFA inihibits cell wall synthesis by targeting pyrophosphate of peptidoglycan precursors .
|
-
- HY-170400
-
-
- HY-136037
-
|
|
ADC Linker
|
Cancer
|
|
Boc-amino-PEG3-SS-acid is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-136991
-
|
|
Antibiotic
|
Others
|
|
Basacv is a DNA-polyintercalating bifunctional compound with DNA-high affinity. Basacv is structurally analogous to the antibiotic anti-tumour drug Triostin A and act as a bis-intercalator .
|
-
- HY-138508
-
|
|
ADC Linker
|
Cancer
|
|
Biotin-PEG2-methyl ethanethioate is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-153428
-
-
- HY-118326
-
|
|
Autophagy
|
Cancer
|
|
MRT 68601 is a potent TBK1 inhibitor with the activity of inhibiting autophagosome formation in lung cancer cells. MRT 68601 may have potential effects against targets associated with host-dependent factors identified in SARS-CoV-2 infection. The drug targets involved in MRT 68601 are related to existing FDA-approved drugs and compounds in clinical trials, which can provide support for the development of broad-spectrum antiviral therapies .
|
-
- HY-B1075AS
-
|
MK-0955 (benzylamine)-13C3
|
Bacterial
Antibiotic
|
Infection
|
|
(Rac)-Fosfomycin (benzylamine)- 13C3 is the 13C labeled Fosfomycin . Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .
|
-
- HY-132253
-
|
|
Antibody-Drug Conjugates (ADCs)
|
Cancer
|
|
Polatuzumab vedotin is an antibody-drug conjugate targeting CD79b. It contains a humanized anti-CD79b IgG1 monoclonal antibody linked to monomethyl auristatin E (MMAE), a potent microtubule inhibitor. The antibody portion is Polatuzumab (HY-P99042), and the drug-linker conjugate for ADC is VcMMAE (HY-15575). Polatuzumab vedotin has the potential for the research of Large B-cell lymphomas (LBCL) .
|
-
- HY-15882
-
|
|
Endogenous Metabolite
|
Cancer
|
|
GNE-783 is a selective CHK1 inhibitor that enhances the activity of gemcitabine. GNE-783 improves the efficacy of anti-metabolite DNA damage drugs by inactivating S-phase and G2-phase cell cycle checkpoints following DNA damage. GNE-783 selectively enhances the chemical synergy of certain drugs in different tumor types, for example, enhancing the activity of temozolomide only in melanoma cell lines .
|
-
- HY-109539
-
|
|
Antibody-Drug Conjugates (ADCs)
Apoptosis
|
Cancer
|
|
Gemtuzumab ozogamicin is an antibody-drug conjugate (ADC) consisting of a humanized immunoglobulin (IgG4) antibody directed against CD33 that is conjugated to the cytotoxic agent Calicheamicin (HY-19609). The antibody portion is Gemtuzumab (HY-P99971), and the drug-linker conjugate for ADC is N-Ac-γ-Calicheamicin-AcBut-NHS ester (HY-103688). Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia (AML) .
|
-
- HY-114315
-
|
|
Quinone Reductase
|
Cancer
|
|
NQO1 substrate acts as an efficient NQO1 substrate and may be a new option for the treatment of NQO1-overexpresssing drug-resistant NSCLC .
|
-
- HY-78932A
-
|
|
ADC Linker
|
Cancer
|
|
Dap-NE hydrochloride is a dipeptide hydrochloride and a cleavable ADC Linker.Dap-NE hydrochloride can be used to connect Antibody and toxin molecules (Cytotoxin) to synthesize Antibody-Drug Conjugates (ADCs) .
|
-
- HY-163153
-
|
|
Apoptosis
|
Cancer
|
|
Anticancer agent 184 (Compound 6o) is a novel, effective and low toxic anticancer drug. Anticancer agent 184 induces apoptosis by blocking the S phase .
|
-
- HY-141190
-
|
|
ADC Linker
|
Cancer
|
|
Gly-Gly-Gly-PEG3-TCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W034595
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis
|
-
- HY-15575G
-
|
MC-Val-Cit-PAB-MMAE; mc-vc-PAB-MMAE
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
VcMMAE (MC-Val-Cit-PAB-MMAE) (GMP) is VcMMAE (HY-15575) produced by using GMP guidelines. VcMMAE is a drug-linker conjugate for ADC .
|
-
- HY-156197
-
-
- HY-169324
-
|
Mal-Exo-EEVC-Exatecan
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
APL-1092 (Mal-Exo-EEVC-Exatecan) is a drug-linker conjugate for ADC, which contains Exatecan (HY-13631) (ADC payload) and a linker .
|
-
- HY-141292
-
|
|
ADC Linker
|
Cancer
|
|
Oleoyl-Gly-Lys-N-(m-PEG11) is a cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-49206
-
|
|
ADC Linker
|
Cancer
|
|
CbzNH-PEG8-amide-bis(pentayl-5OBz) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-136134
-
|
|
ADC Linker
|
Cancer
|
|
SS-bis-amino-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-19371
-
|
|
GABA Receptor
|
Neurological Disease
|
|
Lorediplon is a novel non-benzodiazepine drug acting as a GABAA receptor modulator, differentially active at the alpha1-subunit, associated with promoting sleep.
|
-
- HY-130689
-
|
|
Endogenous Metabolite
|
Neurological Disease
|
|
Pinoxepin hydrochloride is an antipsychotic drug with sedative and antidepressant activities. Pinoxepin hydrochloride is used to suppress mental disorders such as schizophrenia and depression. Pinoxepin hydrochloride also has the effect of improving sleep quality .
|
-
- HY-148002
-
|
|
Drug Metabolite
|
Others
|
|
1'-Hydroxy Midazolam-β-D-glucuronide is a β-D-glucuronide that acts as a drug metabolite, human urine metabolite, and human serum metabolite .
|
-
- HY-W096135
-
|
|
ADC Linker
|
Cancer
|
|
Biotin-PEG1-NH2 is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-126510
-
|
|
ADC Linker
|
Cancer
|
|
MC-PEG2-C2- NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-136135
-
|
|
ADC Linker
|
Cancer
|
|
(2-pyridyldithio)-PEG1-hydrazine is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-170868
-
-
- HY-164574
-
|
|
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
BCN-DOTA is a cyclooctyne-linked DOTA chelator that can be radiolabeled with zirconium-89 as a radionuclide-labeled drug conjugate (RDC) to target specific biomolecules, cells, or tissues.
|
-
- HY-130091
-
|
|
ADC Linker
|
Cancer
|
|
NHPI-PEG4-C2-NHS ester is an ADC Linker, which can be used to synthesize antibody-drug conjugates (ADCs) .
|
-
- HY-171125
-
-
- HY-P4122
-
|
|
HIV
|
Others
|
|
TAT (47-57), FAM-labeled is a cell-penetrating peptide (CPP). TAT (47-57), FAM-labeled has the potential for intracellular drug delivery research .
|
-
- HY-W856812
-
|
|
Drug Intermediate
|
Others
|
|
Penicillanic acid (sodium) is a key drug intermediate. Penicillanic acid (sodium) can be used to synthesize β-lactamase inhibitors and prodrugs. Penicillanic acid (sodium) derivative Mecillinam has antibacterial activity .
|
-
- HY-150074A
-
|
|
ADC Cytotoxin
|
Cancer
|
|
STING agonist-18 diTFA (compound 1a) can be used for synthesis of antibody-drug conjugates (ADCs), such Trastuzumab (HY-P9907) conjugate .
|
-
- HY-17509S
-
-
- HY-P1449A
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
|
-
- HY-144238
-
-
- HY-168548
-
|
|
ADC Linker
|
Cancer
|
|
pAF-Oxime-PEG4-OH serves as a linker for Opadotina (HY-147248) and can be utilized in the preparation of antibody-drug conjugates (ADCs) .
|
-
- HY-119360
-
|
|
Insecticide
|
Others
|
|
Lilly 18947 (free base) is a selective drug-potentiating agent that synergizes carbamate insecticides. Lilly 18947 (free base) inhibits a variety of detoxication mechanisms in mammals .
|
-
- HY-140099
-
|
|
ADC Linker
|
Cancer
|
|
Amino-ethyl-SS-PEG3-NHBoc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-106534
-
|
Preglandin; SC-37681
|
Prostaglandin Receptor
|
Endocrinology
|
|
Gemeprost (Preglandin), a Prostaglandin E1 (HY-B0131) analogue, is a potent antiprogestogen drug. Gemeprost has the potential for second trimester abortion research .
|
-
- HY-141284
-
|
|
ADC Linker
|
Cancer
|
|
Gly-Gly-Gly-PEG4-methyltetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W250408
-
-
- HY-117371
-
|
(-)-Hemiasterlin; Milnamide B
|
ADC Cytotoxin
|
Cancer
|
|
Hemiasterlin ((-)-Hemiasterlin) is an antimitotic marine natural product with potent anticancer effcts. Hemiasterlin can be used as a cytotoxic payload (ADC Cytotoxin) in antibody-drug conjugates (ADCs) .
|
-
- HY-128896
-
-
- HY-21195
-
|
Perfluorohexanesulphonyl fluoride
|
Biochemical Assay Reagents
|
Others
|
|
Perfluorohexylsulfonyl fluoride (Perfluorohexanesulphonyl fluoride) is a perfluoroalkyl and polyfluoroalkyl substances, that is defined as persistant organic pollutant by 2022 Stockholm Convention. Perfluorohexylsulfonyl fluoride can be used for drug modification .
|
-
- HY-N12878
-
|
|
Others
|
Others
|
|
Calleryanin is a phenolic glycoside, which is mainly isolated from Maloideae and Prunus of the family Rosaceae. Calleryanin is used in study of plant defense mechanisms and new drugs development .
|
-
- HY-133538
-
|
|
ADC Linker
|
Cancer
|
|
4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-P2853A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Hemocyanin-SMCC is a hemocyanin that can be used as a carrier protein to couple low molecular weight molecules such as peptides, nucleic acids, drugs or toxins to make them highly immunogenic.
|
-
- HY-159668
-
|
|
ADC Linker
|
Cancer
|
DL002 is a ADC linker that can be used to synthesize antibody-drug conjugates containing BCL-2 family protein degraders, and it's used in tumor research .
|
-
- HY-137910
-
|
|
Herbicide
|
Others
|
|
Tembotrione is a drug that may reduce the
productivity of carrots. Tembotrione has the activity of reducing carrot stem
mass. Tembotrione can be used to study the total productivity of carrot
.
|
-
- HY-N0402R
-
|
Dihydroqinghaosu methyl ether (Standard); Dihydroartemisinin methyl ether (Standard); SM224 (Standard)
|
Reference Standards
Parasite
|
Infection
Inflammation/Immunology
Cancer
|
|
Artemether (Standard) is the analytical standard of Artemether. This product is intended for research and analytical applications. Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria .
|
-
- HY-P4083
-
|
|
Fluorescent Dye
|
Others
|
|
(Arg)9,TAMRA-labeled is a TAMRA-labeled cell permeable peptide. (Arg)9 is a cell-permeable peptide used for drug delivery .
|
-
- HY-164724
-
|
|
ADC Linker
|
Cancer
|
|
Bis-PEG30-NHS ester is a non-claevable 30-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-B0343AS
-
-
- HY-125694
-
|
|
Fungal
|
Infection
|
|
MFB-1041 is an orally active antifungal agent, but exhibits poor oral absorption. MFB-1041 induces the binding of drug to serum albumin .
|
-
- HY-Y1422I
-
|
|
Lipase
|
Others
|
|
Lipase AK comes from Pseudomonas fluorescens and shows good applicability in ester synthesis of food industry, the biofuel synthesis, the synthesis of enantiomeric pure chiral drugs and so on .
|
-
- HY-133459
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W373206
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
Triampizine is a potent gastric antisecretory agent without the side effects of anticholinergic drugs. Triampizine may react with the excipient magnesium stearate and is used in studies of hyperacidity .
|
-
- HY-130962
-
|
|
ADC Linker
|
Cancer
|
|
Ald-Ph-amido-PEG23-OPSS is a cleavable 23 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-164239
-
|
|
Drug-Linker Conjugates for ADC
Microtubule/Tubulin
|
Cancer
|
|
NH2-PEG3-VC-PAB-MMAE is a drug-linker conjugate for ADC, consisting of a cleavable ADC linker (NH2-PEG3-VC-PAB) and a potent tubulin inhibitor Monomethyl auristatin E (MMAE) (HY-15162). NH2-PEG3-VC-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-141155
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable ADC linker conjugated with drug containing 4-unit PEG, which can be used for synthesizing antibody-drug conjugates (ADCs). endo-BCN-PEG4-Val-Cit-PAB-MMAE is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
- HY-W588717
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-Tetraacetyl mannosamine is an organic compound commonly used for chemical alteration and modification in biological research. It can be used to modify glycoproteins, cell surface molecules, and other biomolecules, and is widely used in biomarking and purification techniques. In addition, this compound is used as a carrier for drugs in certain drug controlled release systems. DBCO-Tetraacetyl mannosamine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-P10540
-
|
|
Bacterial
|
Infection
|
|
Pantinin-2 is a cysteine-free toxic peptide found in the emperor scorpion (paninus imperator). Pantinin-2 has high activity against Gram-positive bacteria but weak activity against Gram-negative bacteria. Pantinin-2 also exhibits activity against Candida tropicalis and has relatively mild hemolytic activity against human erythrocytes. Pantinin-2 can be used in the development of antimicrobial drugs for drug-resistant pathogens .
|
-
- HY-152963
-
|
|
Antibody-Drug Conjugates (ADCs)
|
Inflammation/Immunology
Cancer
|
|
Tisotumab vedotin is an antibody drug conjugate (ADC) targeting tissue factor (TF), formed by covalently linking a fully human monoclonal antibody (TF-011) against TF with the microtubule disruptor Monomethyll Auristatin E (MMAE) (HY-15162), and the drug-linker conjugate for ADC is VcMMAE (HY-15575). Tisotumab vedotin has immunomodulatory and anti-tumor activities, and can be used in the study of advanced or metastatic solid tumors such as cervical cancer .
|
-
- HY-141662
-
|
|
STING
Drug-Linker Conjugates for ADC
|
Inflammation/Immunology
Cancer
|
|
2’,3’-cGAMP-C2-PPA is a cyclic dinucleotide interferon gene-stimulating protein (STING) agonist. 2’,3’-cGAMP-C2-PPA is a drug conjugated conjugate used to target antibody-drug conjugated conjugate (ADC) for the treatment of cancer. 2’,3’-cGAMP-C2-PPA can be used in the study of immune and tumor-related diseases .
|
-
- HY-132253A
-
|
|
Antibody-Drug Conjugates (ADCs)
|
Cancer
|
|
Polatuzumab vedotin solution is an antibody-drug conjugate targeting CD79b. It contains a humanized anti-CD79b IgG1 monoclonal antibody linked to monomethyl auristatin E (MMAE), a potent microtubule inhibitor. The antibody portion is Polatuzumab (HY-P99042), and the drug-linker conjugate for ADC is VcMMAE (HY-15575). Polatuzumab vedotin solution has the potential for the research of Large B-cell lymphomas (LBCL) .
|
-
- HY-169986S
-
|
|
JAK
|
Inflammation/Immunology
|
|
TyK2-IN-21-d3 (Compound 3c) is the orally active prodrug of the tyrosine kinase 2. TyK2-IN-21-d3 exhibits good chemical stability in aqueous system under different pHs. TyK2-IN-21-d3 alleviates the effect of gastric acid changes on drug absorption and improve the drug bioavailability in rat model .
|
-
- HY-P99349
-
|
Loncastuximab tesirine-lpyl; ADCT-402
|
Antibody-Drug Conjugates (ADCs)
Apoptosis
|
Cancer
|
|
Loncastuximab tesirine is a human cluster of differentiation 19 (CD19)-directed antibody-drug conjugate (ADC). The antibody portion is Loncastuximab (HY-P99711), and the drug-linker conjugate for ADC is Tesirine (HY-128952). Once bound to CD19 on the cell membrane, loncastuximab tesirine is rapidly internalised and triggers cell death. Loncastuximab tesirin induces cell apoptosis, it can be used for the research of diffuse large B-cell lymphoma .
|
-
- HY-155054
-
|
|
Parasite
|
Infection
|
|
Cysteine protease inhibitor-3 (Compound 15) is a Cysteine protease inhibitor. Cysteine protease inhibitor-3 inhibits Pf3D7, PfW2, PfFP2 and PfFP3 with IC50s of 0.74 μM, 1.05 μM, 3.5 μM, and 4.9 μM, respectively. Cysteine protease inhibitor-3 has anti-plasmodial efficacy against both drug-sensitive and drug-resistant parasites .
|
-
- HY-167706
-
|
|
GPR35
|
Inflammation/Immunology
|
|
Diethyl-Lodoxamide is a highly potent GPR35 agonist with potential to inhibit inflammatory bowel disease. Diethyl-Lodoxamide activates GPR35 in humans, mice and rats, showing similar EC50 values. Diethyl-Lodoxamide can alleviate the clinical symptoms of DSS-induced inflammatory bowel disease in mouse models, and the effect is better than the traditional drug 5-ASA. The pharmaceutical properties of Diethyl-Lodoxamide have been optimized to better meet the requirements of drug design .
|
-
- HY-169810
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
PKZ18 is an antibiotic and inhibits bacterial growth, with MIC values of 32-64 μg/mL against most Gram-positive bacteria. PKZ18 inhibits in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria and directly reduces T-box transcriptional read-through of the associated genes. PKZ18 prevents the codon-anticodon reading required for tRNA binding and is refractory to resistance .
|
-
- HY-103573
-
|
|
mGluR
|
Neurological Disease
|
|
VU 0360223 is a potent metabotropic glutamate receptors (mGluR) negative allosteric modulator with an IC50 of 61 nM .
|
-
- HY-162777
-
|
|
SARS-CoV
|
Infection
|
|
SARS-CoV-2-IN-93 (compound 24) is an inhibitor of SARS-CoV-2 and HCoV-OC43. SARS-CoV-2-IN-93 can be used in antiviral research .
|
-
- HY-W717548
-
|
|
Drug Metabolite
|
Others
|
|
Safinamide acid (Compound Imp-E) is the metabolite of Safinamide (HY-70057). Safinamide acid can be formed by hydrolysis of Safinamide intermediate under alkaline or acidic conditions. Safinamide acid is utilized to monitor process-related impurities and degradation products in safinamide samples .
|
-
- HY-W778423
-
|
Dihydroxy Oxaliplatin-Pt(IV)
|
Drug Intermediate
|
Cancer
|
|
[Pt(DACH)(OH)2(ox)] (Dihydroxy Oxaliplatin-Pt(IV)) is a Oxaliplatin (HY-17371)-based Pt(IV) scaffold. [Pt(DACH)(OH)2(ox)] reacts with N-hydroxysuccinimide (NHS) ester of Pyropheophorbide-a (HY-128973) to yield phorbiplatin. Phorbiplatin is a highly potent Pt(IV) antitumor prodrug .
|
-
![[Pt(DACH)(OH)2(ox)]](//file.medchemexpress.com/product_pic/hy-w778423.gif)
- HY-144833
-
|
|
SARS-CoV
|
Infection
|
|
SARS-CoV-2 3CLpro-IN-1 (Compound 14c) is a potent inhibitor of SARS-CoV-2 3CL pro. 3CL pro (main coronaviruses cysteine-protease) has been identified as a promising target for the development of antiviral agents. SARS-CoV-2 3CLpro-IN-1 has the potential for the research of infection diseases .
|
-
- HY-169257
-
-
- HY-23148
-
|
N-Methylisatin
|
Carboxylesterase (CES)
|
Others
|
|
1-Methylisatin is a potent and selective CE (carboxylesterases) inhibitor, with Kis of 38.2 and 5.38 μM for hiCE and hCE1, respectively. 1-Methylisatin interacts with Hb (human adult hemoglobin) by hydrophobic binding and electrostatic attraction. 1-Methylisatin can be used in the study of regulation of agent metabolism in vivo .
|
-
- HY-76317
-
|
N-Cbz-DL-proline; DL-Cbz-Proline
|
Amino Acid Derivatives
|
Others
|
|
Z-DL-Pro-OH (N-Cbz-DL-proline) is a proline derivative, can be used for the synthesis of agents or other compounds .
|
-
- HY-W008613A
-
|
|
Endogenous Metabolite
|
Metabolic Disease
Cancer
|
|
Amitriptyline pamoate is a common oral anticholinergic. Amitriptyline pamoate
has anticholinergic properties. Amitriptyline pamoate can be used to quantify
anticholinergic adverse reactions in patients taking amitriptyline and placebo
.
|
-
- HY-146394
-
|
|
HBV
DNA/RNA Synthesis
|
Infection
|
|
HBV-IN-22 (Compound LC5f) is an inhibitor of HBV DNA replication with IC50 values of 0.71 μM and 0.84 μM against wild-type and agent resistant HBV strains, respectively .
|
-
- HY-B1355A
-
-
- HY-D1352A
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cyanine7 NHS ester (TEA) is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester (TEA) reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.
|
-
- HY-D1352
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cyanine7 NHS ester potassium is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.
|
-
- HY-17487
-
|
Y 0213; Y 9213
|
COX
|
Neurological Disease
Inflammation/Immunology
|
|
Miroprofen (Y 0213) is an orally active nonsteroidal anti-inflammatory analgesic (NSAID). Miroprofen exhibits anti-inflammatory, analgesic and anti-platelet activities .
|
-
- HY-150649
-
|
|
17β-HSD
|
Cancer
|
|
S07-2005 racemic is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 0.13 μM and 0.75 μM for AKR1C3 and AKR1C4, respectively. S07-2005 racemic has potential as a chemotherapeutic potentiator for cancer agent resistance .
|
-
- HY-19542S1
-
|
C6-Cer-d11; N-Hexanoylsphingosine-d11
|
Apoptosis
Isotope-Labeled Compounds
|
Cancer
|
|
C6 Ceramide-d11 is deuterated labeled C6 Ceramide (HY-19542). C6-ceramide, a ceramide pathway activator, shows activity against a variety of cancer cell lines. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects .
|
-
- HY-W011426
-
|
Propan-2-yl hexadecanoate
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
Isopropyl palmitate is an fatty acid ester. Isopropyl palmitate can be used for design and characterization of bioactive bilayer films. The bilayer membrane not only has the ability to scavenge free radicals and inhibit lipid peroxidation, but also can inhibit the growth of known foodborne pathogens. Isopropyl palmitate can be used as an excipient, such as lubricant, oily carrier, solvent, controlled-release transdermal film. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
|
-
- HY-112624I
-
|
Dextran 3; Dextran D3; Dextran T3(MW 2400-3600)
|
Bacterial
|
Others
|
|
Dextran T3 (Dextran 3; Dextran T3(MW 2400-3600)) is a neural tracer and intestinal permeability probe that can move anterogradely and retrogradely in neuronal axons by passive diffusion. Dextran T3 (MW 3,000) is able to permeate across the intestinal epithelial cell membrane in the presence of cholera toxin-induced cytoskeletal disturbance. Dextran T3 (MW 3,000) is used as a fluorescent marker to rapidly label developing neurons (such as Xenopus retinal ganglion cells) and to assess intestinal barrier function. It can be used to study axonal transport in neuroanatomy and permeability changes in intestinal pathophysiology. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
|
-
- HY-112624H
-
|
Dextran 2; Dextran D2; Dextran T2(MW 1600-2400)
|
Biochemical Assay Reagents
|
Others
|
|
Dextran T2 (Dextran 2; Dextran T2(MW 1600-2400)) is a natural high molecular weight polysaccharide, the glycosidic bonds in its structure can be recognized by endo-dextranase and exo-dextranase. Dextran T2 (MW 2,000) breaks the glycosidic bonds in the enzymatic hydrolysis mechanism, releasing products such as D-glucose, Isomaltose (IM2), and Isomaltotriose (IM3). Dextran T2 (MW 2,000) can be used as a model substrate to characterize the catalytic properties of dextranase (such as optimal pH, temperature and product specificity), and to study enzymatic mechanism research and polysaccharide degradation pathways in glycobiology. The Dextran series of compounds are also a natural polysaccharide drug carrier, which can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity .
|
-
- HY-140112
-
|
|
ADC Linker
|
Cancer
|
|
Acid-PEG2-SS-PEG2-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-B0244
-
|
|
Parasite
Antibiotic
|
Infection
|
|
Praziquantel is a broadly effective trematocide and cestocide, the initial effect of praziquantel on the schistosome may be an interaction of the drug with lipid constituents of the tegumental membrane. Praziquantel is used for the research of schistosomiasis .
|
-
- HY-P2004
-
|
|
MMP
|
Cancer
|
|
FFAGLDD is MMP9 selective cleavage peptides, which used for cytosolic delivery of Doxorubi-cin (DOX) and achieve temporally and spatially controlled slow drug delivery and release .
|
-
- HY-107094
-
|
W-212393 hydrochloride
|
Opioid Receptor
|
Neurological Disease
|
|
MT-7716 hydrochloride (W-212393 hydrochloride) is a selective non-peptide nociceptin receptor (NOP) agonist and promising potential treatment drug for alcohol abuse and relapse prevention .
|
-
- HY-126493A
-
![1-Octylnonyl 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl](2-hydroxyethyl)amino]octanoate](http://file.medchemexpress.com/product_pic/hy-147018.gif)
![Exatecan-amide-bicyclo[1.1.1]pentan-1-ol](http://file.medchemexpress.com/product_pic/hy-160597.gif)
amino]nonadecanedioate](http://file.medchemexpress.com/product_pic/hy-134783.gif)
![Cucurbit[7]uril](http://file.medchemexpress.com/product_pic/hy-104086.gif)
![[1-13Cglc]Lactose monohydrate](http://file.medchemexpress.com/product_pic/hy-w779009.gif)
![N-Methyl-N-[(3-methyldithio)-1-oxopropyl]-L-alanine](http://file.medchemexpress.com/product_pic/hy-w250410.gif)
![[Pt(DACH)(OH)2(ox)]](http://file.medchemexpress.com/product_pic/hy-w778423.gif)
