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EMCV

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13524
    AG-1478
    Maximum Cited Publications
    34 Publications Verification

    Tyrphostin AG-1478; NSC 693255

    		 EGFR HCV Influenza Virus Infection Cardiovascular Disease Metabolic Disease Cancer
    AG-1478 (Tyrphostin AG-1478) is a selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. AG-1478 has antiviral effects against HCV and encephalomyocarditis virus (EMCV).
    AG-1478
  • HY-W063968
    RO8191
    5+ Cited Publications

    CDM-3008; RO4948191

    		 IFNAR JAK STAT HCV HBV Infection
    RO8191 (CDM-3008), an imidazonaphthyridine compound, is an orally active and potent interferon (IFN) receptor agonist. RO8191 directly binds to IFNα/β receptor 2 (IFNAR2) and activates IFN-stimulated genes (ISGs) expression and JAK/STAT phosphorylation. RO8191 shows antiviral activity against both HCV and EMCV with an IC50 of 200 nM for HCV replicon . RO8191 is a cccDNA modulator (CDM) through interferon-like activity and has anti-HBV activity .
    RO8191
  • HY-117318
    PDE12-IN-1

    		Phosphodiesterase (PDE) Infection
    PDE12-IN-1 is a potent and selective PDE12 inhibitor with a pIC50 value for enzyme inhibition of 9.1. PDE12-IN-1 increases 2′,5′-linked adenylate polymers (2-5A) levels, and the pEC50 value is 7.7. PDE12-IN-1 shows antiviral activity .
    PDE12-IN-1
  • HY-13524A
    AG-1478 hydrochloride

    Tyrphostin AG-1478 hydrochloride; NSC 693255 hydrochloride

    		 EGFR HCV Influenza Virus Infection Cardiovascular Disease Metabolic Disease Cancer
    AG-1478 hydrochloride (Tyrphostin AG-1478 hydrochloride) is a selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. AG-1478 hydrochloride has antiviral effects against HCV and encephalomyocarditis virus (EMCV) .
    AG-1478 hydrochloride

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