2. Search Result
Search Result
Isoforms Recommended: Estrogen receptor
Results for "

ER

" in MedChemExpress (MCE) Product Catalog:

335

Inhibitors & Agonists

2

Screening Libraries

9

Fluorescent Dye

11

Peptides

49

Natural
Products

17

Recombinant Proteins

25

Isotope-Labeled Compounds

3

Antibodies

3

Click Chemistry

Species:
Tag:
Source:
Cat. No. Compare Product Name Species Source
  • HY-P70248
    ER alpha/ESR1 Protein, Human (His)

    rHuEstrogen receptor/ER alpha, His; Estrogen Receptor; ER; ER-Alpha; Estradiol Receptor; Nuclear Receptor Subfamily 3 Group A MembER 1; ESR1; ESR; NR3A1

    		 Human E. coli
    The ER α/ESR1 protein is a nuclear receptor that plays a critical regulatory role in gene expression, affecting cell proliferation and differentiation. Ligand-dependent transactivation involves binding of homodimers to estrogen response elements or association with transcription factors. ER alpha/ESR1 Protein, Human (His) is the recombinant human-derived ER alpha/ESR1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of ER alpha/ESR1 Protein, Human (His) is 116 a.a., with molecular weight of ~14 kDa.
  • HY-P7011
    Epiregulin Protein, Human
    1 Publications Verification

    rHuEpiregulin; EREG; EPR

    		 Human E. coli
    Epiregulin Protein, Human is a growth regulator and a member of the epidermal growth factor (EGF) family. Epiregulin is a tumor growth-inhibitory factor inducing morphological changes in human epidermoid carcinoma HeLa cells.
  • HY-P701106
    ER alpha/ESR1 Protein, Human (P. pastoris, N-His)

    rHuEstrogen receptor/ER alpha, His; Estrogen Receptor; ER; ER-Alpha; Estradiol Receptor; Nuclear Receptor Subfamily 3 Group A MembER 1; ESR1; ESR; NR3A1

    		 Human P. pastoris
    The ER α/ESR1 protein is a nuclear receptor that plays a critical regulatory role in gene expression, affecting cell proliferation and differentiation. Ligand-dependent transactivation involves binding of homodimers to estrogen response elements or association with transcription factors. ER alpha/ESR1 Protein, Human (P. pastoris, N-His) is the recombinant human-derived ER alpha/ESR1 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of ER alpha/ESR1 Protein, Human (P. pastoris, N-His) is 586 a.a., with molecular weight of ~67.2 kDa.
  • HY-P70791
    ER beta/ESR2 Protein, Human (His)

    Estrogen Receptor Beta; ER-Beta; Nuclear Receptor Subfamily 3 Group A MembER 2; ESR2; ESTRB; NR3A2

    		 Human E. coli
    ER beta/ESR2 Protein, a nuclear hormone receptor, binds estrogens akin to ESR1/ER-alpha. It activates estrogen-dependent reporter genes with ERE. However, it lacks ligand binding ability and exhibits minimal ERE binding, resulting in the loss of ligand-dependent transactivation ability. ER beta/ESR2 Protein, Human (His) is the recombinant human-derived ER beta/ESR2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of ER beta/ESR2 Protein, Human (His) is 323 a.a., with molecular weight of 35-40 kDa.
  • HY-P71113
    PDIA4 Protein, Human (HEK293, His)

    Protein Disulfide-IsomERase A4; Endoplasmic Reticulum Resident Protein 70; ER Protein 70; ERp70; Endoplasmic Reticulum Resident Protein 72; ER Protein 72; ERp-72; ERp72; PDIA4; ERP70; ERP72

    		 Human HEK293
    The PDIA4 protein plays a key role in the chaperone complex, cooperating with various proteins. This dynamic assembly, including DNAJB11, HSP90B1 and others, orchestrates complex cellular processes. PDIA4 Protein, Human (HEK293, His) is the recombinant human-derived PDIA4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PDIA4 Protein, Human (HEK293, His) is 625 a.a., with molecular weight of ~75.0 kDa.
  • HY-P70901
    TXNDC4 Protein, Human (HEK293, His)

    Thioredoxin domain-containing protein 4; ER protein 44; KIAA0573; TXNDC4

    		 Human HEK293
    The TXNDC4 protein is critical in cellular processes, mediating thiol-dependent retention in the early secretory pathway. Its conserved CRFS motif forms mixed disulfide bonds with substrate proteins to control oxidative protein folding in the endoplasmic reticulum and maintain cellular redox balance. TXNDC4 Protein, Human (HEK293, His) is the recombinant human-derived TXNDC4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TXNDC4 Protein, Human (HEK293, His) is 373 a.a., with molecular weight of ~50.0 kDa.
  • HY-P71046
    TXNDC12 Protein, Human (HEK293, His)

    Thioredoxin Domain-Containing Protein 12; Endoplasmic Reticulum Resident Protein 18; ER Protein 18; ERp18; Endoplasmic Reticulum Resident Protein 19; ER Protein 19; ERp19; Thioredoxin-Like Protein p19; hTLP19; TXNDC12; TLP19

    		 Human HEK293
    The TXNDC12 protein is an important endoplasmic reticulum-localized protein disulfide bond reductase that plays a key role in promoting disulfide bond formation in client proteins. As an essential component of cellular machinery, TXNDC12 contributes to complex protein folding processes, highlighting its importance in maintaining correct protein structure and function. TXNDC12 Protein, Human (HEK293, His) is the recombinant human-derived TXNDC12 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TXNDC12 Protein, Human (HEK293, His) is 142 a.a., with molecular weight of ~18.0 kDa.
  • HY-P77087
    MMGT1 Protein, Human (HEK293, His)

    ER membrane protein complex subunit 5; Transmembrane protein 32; EMC5; TMEM32

    		 Human HEK293
    The MMGT1 protein is an important member of the endoplasmic reticulum membrane protein complex (EMC) and is essential for the independent insertion of newly synthesized membrane proteins into the endoplasmic reticulum (ER) membrane. Its preference for transmembrane domains with weak hydrophobicity or unstable characteristics guides co- and post-translational insertion processes. MMGT1 Protein, Human (HEK293, His) is the recombinant human-derived MMGT1 protein, expressed by HEK293 , with N-His labeled tag. The total length of MMGT1 Protein, Human (HEK293, His) is 66 a.a., with molecular weight of 23-29 kDa.
  • HY-P70957
    MAN1B1 Protein, Human (HEK293, His)

    Endoplasmic Reticulum Mannosyl-Oligosaccharide 1; 2-Alpha-Mannosidase; ER Alpha-1; 2-Mannosidase; ER Mannosidase 1; ERMan1; Man9GlcNAc2-Specific-Processing Alpha-Mannosidase; Mannosidase Alpha Class 1B MembER 1; MAN1B1

    		 Human HEK293
    MAN1B1, integral to glycoprotein quality control, trims a single alpha-1,2-linked mannose from Man(9)GlcNAc(2), producing Man(8)GlcNAc(2). In the ERQC, elevated enzyme concentrations allow further trimming to Man(5-6)GlcNAc(2). This enzymatic function is crucial for glycoprotein processing and quality control in the endoplasmic reticulum, ensuring proper folding and maturation. MAN1B1 Protein, Human (HEK293, His) is the recombinant human-derived MAN1B1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of MAN1B1 Protein, Human (HEK293, His) is 594 a.a., with molecular weight of 58-80 kDa.
  • HY-P76897
    EDEM2 Protein, Human (HEK293, His)

    ER degradation-enhancing alpha-mannosidase-like protein 2; C20orf31; C20orf49

    		 Human HEK293
    EDEM2 Protein is involved in the endoplasmic reticulum-associated degradation (ERAD) pathway. EDEM2 Protein, Human (HEK293, His) is the recombinant human-derived EDEM2 protein, expressed by HEK293 , with C-His labeled tag. The total length of EDEM2 Protein, Human (HEK293, His) is 471 a.a., with molecular weight of 50-75 kDa.
  • HY-P70891
    ERP27 Protein, Human (HEK293, His)

    Endoplasmic Reticulum Resident Protein 27; ER Protein 27; ERp27; ERP27; C12orf46

    		 Human HEK293
    The ERP27 protein has a unique role in that it can specifically bind unfolded proteins and recruit the protein disulfide isomerase PDIA3 to the substrate through the hydrophobic pocket in its C-terminal domain. This interaction implies that ERP27 is involved in the unfolding stress response and resolves challenges in cellular proteostasis. ERP27 Protein, Human (HEK293, His) is the recombinant human-derived ERP27 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of ERP27 Protein, Human (HEK293, His) is 248 a.a., with molecular weight of 32-38 kDa.
  • HY-P71727
    CHGA Protein, Human (P.pastoris, His)

    beta Granin; catestatin; CgA; CHG A; ChromograninA; ER-37; SPI; vasostatin 2; Vasostatin; Vasostatin I; Vasostatin II; vasostatin-2

    		 Human P. pastoris
    CHGA protein robustly inhibits glucose-induced insulin release from the pancreas, functioning as a non-competitive nicotinic cholinergic antagonist. It inhibits catecholamine release, displays antibacterial activity, induces mast cell responses, and scavenges free radicals. CHGA may also regulate cardiac function and blood pressure. CHGA Protein, Human (P.pastoris, His) is the recombinant human-derived CHGA protein, expressed by P. pastoris , with N-His labeled tag. The total length of CHGA Protein, Human (P.pastoris, His) is 439 a.a., with molecular weight of ~50.9 kDa.
  • HY-P702352
    KDELR2 Protein, Mouse (Cell-Free, His)

    ER lumen protein-retaining receptor 2; KDEL endoplasmic reticulum protein retention receptor 2; KDEL receptor 2

    		 Mouse E. coli Cell-free
    KDELR2 Protein, a membrane receptor, crucially maintains endoplasmic reticulum (ER) resident proteins' localization. It binds the K-D-E-L sequence motif, retaining these proteins within the ER. This interaction facilitates vesicle-mediated recycling, ensuring proper subcellular localization through Golgi-to-ER protein return. KDELR2's pH-dependent binding, optimal at pH 5-5.4, underscores the regulatory role of pH in this vital cellular process. KDELR2 Protein, Mouse (Cell-Free, His) is the recombinant mouse-derived KDELR2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of KDELR2 Protein, Mouse (Cell-Free, His) is 212 a.a., with molecular weight of 26.0 kDa.
  • HY-P77342
    COX4NB Protein, Human (His)

    ER membrane protein complex subunit 8; Neighbor of COX4; C16orf2; COX4AL; COX4NB; FAM158B; NOC4

    		 Human E. coli
    COX4NB protein is a component of the endoplasmic reticulum membrane protein complex (EMC) and is able to insert newly synthesized membrane proteins into the endoplasmic reticulum membrane in an energy-independent manner. Its preference for transmembrane domains with weakly hydrophobic or unstable characteristics guides co- and post-translational insertion processes. COX4NB Protein, Human (His) is the recombinant human-derived COX4NB protein, expressed by E. coli , with N-His labeled tag. The total length of COX4NB Protein, Human (His) is 210 a.a., with molecular weight of ~27 kDa.
  • HY-P71193
    PDIA6 Protein, Human (HEK293, His)

    Protein Disulfide-IsomERase A6; Endoplasmic Reticulum Protein 5; ER Protein 5; ERp5; Protein Disulfide IsomERase P5; Thioredoxin Domain-Containing Protein 7; PDIA6; ERP5; P5; TXNDC7

    		 Human HEK293
    PDIA6 protein has molecular chaperone activity, which can inhibit the aggregation of misfolded proteins and contribute to quality control. It negatively regulates the unfolded protein response (UPR) by binding to ERN1 and inhibiting its signaling. PDIA6 Protein, Human (HEK293, His) is the recombinant human-derived PDIA6 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PDIA6 Protein, Human (HEK293, His) is 421 a.a., with molecular weight of ~52.0 kDa.
  • HY-P71609
    TXNDC5 Protein, Human (GST)

    EndoPDI; Endoplasmic reticulum protein ERp46; Endoplasmic reticulum resident protein 46; Endothelial protein disulphide isomERase; ER protein 46; ERp46; Hcc 2; MGC3178; PDIA15; TLP46; TXND5_HUMAN; TXNDC 5; Txndc5

    		 Human E. coli
    TXNDC5 Protein, an endoplasmic reticulum lumen-based disulfide isomerase, crucially aids in forming disulfide bonds for protein stability and function. Its ability to reduce disulfide bonds in insulin highlights its role in intricate protein folding processes. TXNDC5's functional attributes make it a key player in preserving the structural integrity of endoplasmic reticulum proteins, contributing to cellular homeostasis. TXNDC5 Protein, Human (GST) is the recombinant human-derived TXNDC5 protein, expressed by E. coli , with N-GST labeled tag. The total length of TXNDC5 Protein, Human (GST) is 324 a.a., with molecular weight of ~63.2 kDa.
  • HY-P71917
    P4HB Protein, Human (His)

    Cellular thyroid hormone binding protein; Cellular thyroid hormone-binding protein; Collagen prolyl 4 hydroxylase beta; Disulphide IsomERase; DSI; EC 5.3.4.1; ER protein 59; ERBA2L; ERp59; GIT; P4HB; P4Hbeta; p55; PDI; PDIA1; PDIA1_HUMAN; PDIR; PHDB; PO4DB; PO4HB; PROHB; Protocollagen hydroxylase; Thbp;

    		Human E. coli
    The P4HB protein is a multifunctional entity that catalyzes disulfide bonding processes at the cell surface and within cells. As a reductase, it modifies outer surface proteins and participates in the formation of disulfide bonds in nascent proteins. P4HB Protein, Human (His) is the recombinant human-derived P4HB protein, expressed by E. coli , with N-6*His labeled tag. The total length of P4HB Protein, Human (His) is 490 a.a., with molecular weight of ~56 kDa.

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: