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Pathways Recommended: MAPK/ERK Pathway
Results for "

ERK

" in MedChemExpress (MCE) Product Catalog:

420

Inhibitors & Agonists

5

Screening Libraries

2

Fluorescent Dye

2

Biochemical Assay Reagents

38

Peptides

3

Inhibitory Antibodies

93

Natural
Products

22

Recombinant Proteins

16

Isotope-Labeled Compounds

25

Antibodies

4

Click Chemistry

Cat. No. Compare Product Name Species Source
  • HY-P73001

    EPHB2; Ephrin type-B receptor 2; EK5; DRT; EPHT3; ERK; HEK5; TYRO5

    Human HEK293
    EphB2 protein is a receptor tyrosine kinase that participates in bidirectional signaling with the transmembrane ephrin B ligand. It guides commissural axons in the developing cerebral cortex, efferent growth cones of the inner ear, and retinal ganglion cell axons. EphB2 Protein, Human (HEK293, His-Fc) is the recombinant human-derived EphB2 protein, expressed by HEK293 , with C-hFc, C-8*His labeled tag. The total length of EphB2 Protein, Human (HEK293, His-Fc) is 525 a.a., with molecular weight of approximately 95 kDa.
  • HY-P702710

    EPHB2; EPH receptor B2; DRT, EphB2 , EPHT3, ERK; ephrin type-B receptor 2; Hek5; Tyro5; EPH-like kinase 5; eph tyrosine kinase 3; elk-related tyrosine kinase; protein-tyrosine kinase HEK5; tyrosine-protein kinase TYRO5; renal carcinoma antigen NY-REN-47; tyrosine-protein kinase receptor EPH-3; developmentally-regulated Eph-related tyrosine kinase; DRT; EK5; ERK; CAPB; PCBC; EPHT3; MGC87492

    Human Sf9 insect cells
  • HY-P700716

    DRT; ERK; HEK5; TYRO5; CAPB; EK5; EPHT3; PCBC; Cek5; EphB2; EPHT3MGC87492; Nuk; Qek2; Sek3

    Cynomolgus HEK293
    The EphB2 protein is a receptor tyrosine kinase that binds to the transmembrane ephrin B ligand on adjacent cells to initiate bidirectional signaling. The forward signal originates from the receptor, while the reverse signal originates from the ephrin ligand. EphB2 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived EphB2 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphB2 Protein, Cynomolgus (HEK293, His) is 524 a.a., with molecular weight of 65-75 kDa.
  • HY-P702735

    MAPK1; mitogen-activated protein kinase 1; PRKM1, PRKM2; ERK; ERK2; MAPK2; p41mapk; ERK-2; MAPK 2; p42-MAPK; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; protein tyrosine kinase ERK2; mitogen-activated protein kinase 2; extracellular signal-regulated kinase 2; p38; p40; p41; ERT1; PRKM1; PRKM2; P42MAPK

    Human E. coli
  • HY-P73000

    EPHB2; Ephrin type-B receptor 2; EK5; DRT; EPHT3; ERK; HEK5; TYRO5

    Human Sf9 insect cells
    EphB2 protein is a receptor tyrosine kinase that participates in bidirectional signaling with the transmembrane ephrin B ligand. It guides commissural axons in the developing cerebral cortex, efferent growth cones of the inner ear, and retinal ganglion cell axons. EphB2 Protein, Human (sf9, His-GST) is the recombinant human-derived EphB2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of EphB2 Protein, Human (sf9, His-GST) is 418 a.a., with molecular weight of ~65 kDa.
  • HY-P75237

    EPHB2; Ephrin type-B receptor 2; EK5; DRT; EPHT3; ERK; HEK5; TYRO5

    Human HEK293
    EphB2 protein is a receptor tyrosine kinase that participates in bidirectional signaling with the transmembrane ephrin B ligand. It guides commissural axons in the developing cerebral cortex, efferent growth cones of the inner ear, and retinal ganglion cell axons. EphB2 Protein, Human (HEK293, His) is the recombinant human-derived EphB2 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphB2 Protein, Human (HEK293, His) is 525 a.a., with molecular weight of 70-75 kDa.
  • HY-P75236

    EPHB2; Ephrin type-B receptor 2; EK5; DRT; EPHT3; ERK; HEK5; TYRO5

    Mouse HEK293
    EphB2 protein is a member of the Eph receptor family and has a ligand-binding domain, a transmembrane region, and an intracellular kinase domain. It preferentially binds ephrin-B ligands and plays a role in nervous system and vascular development. EphB2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived EphB2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of EphB2 Protein, Mouse (HEK293, Fc) is 522 a.a., with molecular weight of ~96.6 kDa.
  • HY-P75235

    EPHB2; Ephrin type-B receptor 2; EK5; DRT; EPHT3; ERK; HEK5; TYRO5

    Mouse HEK293
    The EphB2 protein is a receptor tyrosine kinase that binds to the transmembrane ephrin B ligand on adjacent cells to initiate bidirectional signaling. The forward signal originates from the receptor, while the reverse signal originates from the ephrin ligand. EphB2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived EphB2 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphB2 Protein, Mouse (HEK293, His) is 540 a.a., with molecular weight of ~65 kDa.
  • HY-P75223

    Mitogen-activated protein kinase 1; MAPK 1; ERT1; ERK-2; p42-MAPK

    Human Sf9 insect cells
    ERK2 Protein, a key component of the MAPK/ERK cascade, regulates diverse cellular processes such as transcription, translation, mitosis, apoptosis, endosomal dynamics, and Golgi apparatus fragmentation. Through phosphorylation, it modulates substrates including transcription factors, cytoskeletal elements, apoptosis regulators, translation regulators, protein kinases, and phosphatases. ERK2 Protein, Human (sf9, His) is the recombinant human-derived ERK2 protein, expressed by Sf9 insect cells , with C-His labeled tag.
  • HY-P701678

    MAPK3; Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1

    Human E. coli
    ERK1 protein is an important serine/threonine kinase in the MAP kinase pathway and cooperates with MAPK1/ERK2 to activate the MAPK/ERK cascade. Stimulated by KIT and KITLG/SCF, this pathway plays a key role in cell growth, adhesion, survival, and differentiation. ERK1 Protein, Human (GST) is the recombinant human-derived ERK1 protein, expressed by E. coli , with N-GST labeled tag. The total length of ERK1 Protein, Human (GST) is 378 a.a., .
  • HY-P701679

    MAPK6; Mitogen-activated protein kinase 6; MAP kinase 6; MAPK 6; Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97; p97-MAPK

    Human E. coli
    ERK3 Protein, an atypical MAPK, phosphorylates MAP2 and MAPKAPK5. Interacting with MAPKAPK5, ERK3/MAPK6 undergoes Ser-189 phosphorylation, facilitating MAPKAPK5 activation. Activated MAPKAPK5 reciprocally phosphorylates ERK3/MAPK6. The complex's precise functional implications, especially in cell cycle entry, remain elusive. ERK3 Protein, Human is the recombinant human-derived ERK3 protein, expressed by E. coli , with tag free. The total length of ERK3 Protein, Human is 319 a.a., .
  • HY-P701680

    MAPK6; Mitogen-activated protein kinase 6; MAP kinase 6; MAPK 6; Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97; p97-MAPK

    Human E. coli
    ERK3 Protein, an atypical MAPK, phosphorylates MAP2 and MAPKAPK5. Interacting with MAPKAPK5, ERK3/MAPK6 undergoes Ser-189 phosphorylation, facilitating MAPKAPK5 activation. Activated MAPKAPK5 reciprocally phosphorylates ERK3/MAPK6. The complex's precise functional implications, especially in cell cycle entry, remain elusive. ERK3 Protein, Human (His) is the recombinant human-derived ERK3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of ERK3 Protein, Human (His) is 319 a.a., .
  • HY-P76532

    Mitogen-activated protein kinase 12; Extracellular signal-regulated kinase 6; ERK-6; SAPK3

    Human Sf9 insect cells
    The p38 gamma/MAPK12 protein is an important serine/threonine kinase in the MAP kinase pathway and can respond to extracellular stimuli such as pro-inflammatory cytokines or stress. p38 MAPK activates transcription factors such as ELK1 and ATF2, each of which phosphorylates approximately 200 to 300 substrates. p38 gamma/MAPK12 Protein, Human (sf9) is the recombinant human-derived p38 gamma/MAPK12 protein, expressed by Sf9 insect cells , with tag free and with residual Gly-Pro in N-terminal (not related to functional changes).
  • HY-P76533

    Mitogen-activated protein kinase 12; Extracellular signal-regulated kinase 6; ERK-6; SAPK3

    Human Sf9 insect cells
    The p38 gamma/MAPK12 protein is an important serine/threonine kinase in the MAP kinase pathway and can respond to extracellular stimuli such as pro-inflammatory cytokines or stress. p38 MAPK activates transcription factors such as ELK1 and ATF2, each of which phosphorylates approximately 200 to 300 substrates. p38 gamma/MAPK12 Protein, Human (sf9, His-GST) is the recombinant human-derived p38 gamma/MAPK12 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
  • HY-P701803

    MAPK4; Mitogen-activated protein kinase 4; MAP kinase 4; MAPK 4; Extracellular signal-regulated kinase 4; ERK-4; MAP kinase isoform p63; p63-MAPK

    Human Sf9 insect cells
    MAPK4, an atypical MAPK protein, phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5, forming a complex with intricate phosphorylation events. Interaction with MAPKAPK5 leads to ERK3/MAPK6 phosphorylation at Ser-189, activating MAPKAPK5, which reciprocally phosphorylates ERK3/MAPK6. The specific cellular role of this interplay, while unclear, suggests ERK3's potential involvement in promoting entry into the cell cycle. MAPK4 Protein, Human (Sf9, His, GST) is the recombinant human-derived MAPK4 protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of MAPK4 Protein, Human (Sf9, His, GST) is 586 a.a., .
  • HY-P700593

    MEKK; MEKK1; SRXY6; MEKK 1; MAPKKK1; MAP/ERK kinase kinase 1; MAPK/ERK kinase kinase 1; MEK kinase 1; mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase; mitogen-activated protein kinase kinase kinase 1

    Mouse E. coli
    MAP3K1 is a key component of the protein kinase signal transduction cascade and plays a crucial role in cell signaling pathways. Through its kinase activity, MAP3K1 coordinates the activation of the ERK and JNK kinase pathways by phosphorylating MAP2K1 and MAP2K4. MAP3K1 Protein, Mouse (His) is the recombinant mouse-derived MAP3K1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of MAP3K1 Protein, Mouse (His) is 278 a.a., with molecular weight of 34.8 kDa.
  • HY-P701705

    MAP3K5; Mitogen-activated protein kinase kinase kinase 5; Apoptosis signal-regulating kinase 1; ASK-1; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5

    Human E. coli
    ASK1 protein is a key serine/threonine kinase in the MAP kinase pathway, coordinating cellular responses to environmental changes and affecting cell fate, differentiation, and survival. ASK1 is a key player in apoptosis and promotes mitochondria-dependent caspase activation. ASK1 Protein, Human (His) is the recombinant human-derived ASK1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of ASK1 Protein, Human (His) is 298 a.a., .
  • HY-P701801

    MINK1; Misshapen-like kinase 1; GCK family kinase MiNK; MAPK/ERK kinase kinase kinase 6; MEK kinase kinase 6; MEKKK 6; Misshapen/NIK-related kinase; Mitogen-activated protein kinase kinase kinase kinase 6

    Human Sf9 insect cells
    MAP4K6 protein is a key serine/threonine kinase that negatively regulates Ras-related Rap2-mediated signaling, affecting neuronal structure and AMPA receptor trafficking. Its importance is underlined by its important role in regulating synaptic density, dendritic complexity, and surface AMPA receptor expression in hippocampal neurons. MAP4K6 Protein, Human (Sf9, GST) is the recombinant human-derived MAP4K6 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of MAP4K6 Protein, Human (Sf9, GST) is 314 a.a., .
  • HY-P700589

    MAP2K4; mitogen-activated protein kinase kinase 4; SERK1; dual specificity mitogen-activated protein kinase kinase 4; JNKK1; MEK4; MKK4; PRKMK4; MEK 4; MAPKK 4; SAPK kinase 1; MAPK/ERK kinase 4; SAPK/ERK kinase 1; MAP kinase kinase 4; JNK-activated kinase 1; JNK activating kinase 1; JNK-activating kinase 1; c-Jun N-terminal kinase kinase 1; stress-activated protein kinase kinase 1; JNKK; SEK1; MAPKK4; SAPKK1; SAPKK-1

    Human P. pastoris
    The MAP2K4 protein is a dual-specificity kinase involved in the MAP kinase pathway. MAP2K4 Protein, Human (P. pastoris, His-GST) is the recombinant human-derived MAP2K4 protein, expressed by P. pastoris , with N-6*His, N-GST labeled tag. The total length of MAP2K4 Protein, Human (P. pastoris, His-GST) is 398 a.a., with molecular weight of 71.5 kDa.
  • HY-P700592

    MAP2K6; mitogen-activated protein kinase kinase 6; MEK6; MKK6; MAPKK6; PRKMK6; SAPKK3; protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6); EC 2.7.12.2; Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 6; MAPK/ERK kinase 6

    Human Sf9 insect cells
    The MKK6 protein is a dual-specificity kinase involved in the MAP kinase pathway. MAP2K6 Protein, Human (Baculovirus, His) is the recombinant human-derived MAP2K6 protein, expressed by Sf9 insect cells , with N-6*His labeled tag.
  • HY-P701798

    MAP2K7; Dual specificity mitogen-activated protein kinase kinase 7; MAP kinase kinase 7; MAPKK 7; JNK-activating kinase 2; MAPK/ERK kinase 7; MEK 7; Stress-activated protein kinase kinase 4; SAPK kinase 4; SAPKK-4; SAPKK4; c-Jun N-terminal kinase kinase 2; JNK kinase 2; JNKK 2

    Human Sf9 insect cells
    MAP2K7 protein is a dual-specificity kinase involved in the MAP kinase signal transduction pathway. MAP2K7 Protein, Human (Sf9) is the recombinant human-derived MAP2K7 protein, expressed by Sf9 insect cells , with tag free. The total length of MAP2K7 Protein, Human (Sf9) is 418 a.a., .
  • HY-P701799

    MAP2K7; Dual specificity mitogen-activated protein kinase kinase 7; MAP kinase kinase 7; MAPKK 7; JNK-activating kinase 2; MAPK/ERK kinase 7; MEK 7; Stress-activated protein kinase kinase 4; SAPK kinase 4; SAPKK-4; SAPKK4; c-Jun N-terminal kinase kinase 2; JNK kinase 2; JNKK 2

    Human Sf9 insect cells
    MAP2K7 protein is a dual-specificity kinase involved in the MAP kinase signal transduction pathway. MAP2K7 Protein, Human (Sf9, His, GST) is the recombinant human-derived MAP2K7 protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of MAP2K7 Protein, Human (Sf9, His, GST) is 418 a.a., .