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FAK-IN-2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-144448
    FAK-IN-2

    		FAK Apoptosis Cancer
    FAK-IN-2 is a potent and orally active focal adhesion kinase (FAK) inhibitor, with anticancer activity (FAK IC50= 35 nM). FAK-IN-2 covalently inhibits the autophosphorylation of FAK in a dose-dependent manner, and inhibits the clone formation and migration of tumor cells, inducing apoptosis .
    <em>FAK-IN-2</em>
  • HY-128580
    FAK inhibitor 2
    1 Publications Verification

    		 FAK Cancer
    FAK inhibitor 2 is a potent focal adhesion kinase (FAK) inhibitor with an IC50  of 0.07 nM, with antitumor and anti-angiogenesis activities .
    <em>FAK inhibitor 2</em>
  • HY-15322
    PRT062607

    P505-15; PRT-2607; BIIB-057

    		 Syk Inflammation/Immunology
    PRT062607(P505-15; PRT-2607; BIIB-057) is a highly specific and potent inhibitor of Syk with IC50 of 1-2 nM; >80-fold selective for Syk than Fgr, Lyn, FAK, Pyk2 and Zap70.
    PRT062607

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