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FLT3/STK1

" in MedChemExpress (MCE) Product Catalog:

1

Inhibitors & Agonists

8

Recombinant Proteins

Targets Recommended: FLT3

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-19897

4SC-203

4SC-203 is a potent multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively FLT3/STK1, FLT3 mutated forms, and VEGFRs ^[1].

Species:	Human (6) Mouse (1) Cynomolgus (1)
Tag:	His (4) Avi (1) Fc (4)
Source:	HEK293 (7) Sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source

	FLT3 Protein, Human (HEK293, Fc) 2 Publications Verification rHuReceptor-Type Tyrosine-Protein Kinase FLT3/FLT3, Fc; Receptor-Type Tyrosine-Protein Kinase FLT3; FL Cytokine Receptor; Fetal Liver Kinase-2; FLK-2; Fms-Like Tyrosine Kinase 3; FLT-3; Stem Cell Tyrosine Kinase 1; STK-1; CD135; FLT3; FLK2; STK1	Human	HEK293
	FLT3 is a tyrosine-protein kinase receptor that regulates differentiation, proliferation, and survival of hematopoietic progenitor cells and dendritic cells. It phosphorylates downstream effectors such as SHC1 and AKT1, activating signaling cascades involving MTOR, RAS, and MAP kinases. FLT3 Protein, Human (HEK293, Fc) is the recombinant human-derived FLT3 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of FLT3 Protein, Human (HEK293, Fc) is 515 a.a., with molecular weight of ~120.0 kDa.

	FLT3 Protein, Mouse (HEK293, His) CD135; FL cytokine receptor; FLK2; Flk-2; FLT-3; STK-1	Mouse	HEK293
	FLT3, a receptor tyrosine kinase, has diverse functions including kinase activation, PI3K binding, and ligase binding. It plays a vital role in hematopoiesis, immune function, and tissue development. FLT3 is expressed in various tissues like the brain, immune system, and reproductive system. It is involved in diseases like leukemia and cancer. The wide functions and tissue-specific expression emphasize FLT3's importance in health and disease. FLT3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived FLT3 protein, expressed by HEK293 , with C-His labeled tag. The total length of FLT3 Protein, Mouse (HEK293, His) is 517 a.a., with molecular weight of approximately 88-100 kDa.

	FLT3 Protein, Cynomolgus (HEK293, hFc) CD135; FLK2; STK-1; FLT-3	Cynomolgus	HEK293
	FLT3 is a tyrosine-protein kinase receptor that regulates differentiation, proliferation, and survival of hematopoietic progenitor cells and dendritic cells. It phosphorylates downstream effectors such as SHC1 and AKT1, activating signaling cascades involving MTOR, RAS, and MAP kinases. FLT3 Protein, Cynomolgus (HEK293, hFc) is the recombinant cynomolgus-derived FLT3 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of FLT3 Protein, Cynomolgus (HEK293, hFc) is 514 a.a., with molecular weight of 160-180 kDa.

	FLT3 Protein, Human (HEK293, His-Avi) CD135; FLK2; STK-1; FLT-3	Human	HEK293
	FLT3 is a tyrosine-protein kinase receptor that regulates differentiation, proliferation, and survival of hematopoietic progenitor cells and dendritic cells. It phosphorylates downstream effectors such as SHC1 and AKT1, activating signaling cascades involving MTOR, RAS, and MAP kinases. FLT3 Protein, Human (HEK293, His-Avi) is the recombinant human-derived FLT3 protein, expressed by HEK293 , with C-His, C-Avi labeled tag. The total length of FLT3 Protein, Human (HEK293, His-Avi) is 515 a.a., with molecular weight of 75-100 kDa.

	FITC-Labeled FLT3 Protein, Human (HEK293, Fc) FLT-3; Flk-2; STK-1; CD135; FLK2; FLT-3	Human	HEK293
	FLT3 is a tyrosine-protein kinase receptor that regulates differentiation, proliferation, and survival of hematopoietic progenitor cells and dendritic cells. It phosphorylates downstream effectors such as SHC1 and AKT1, activating signaling cascades involving MTOR, RAS, and MAP kinases. FITC-Labeled FLT3 Protein, Human (HEK293, Fc) is the recombinant human-derived FITC-Labeled FLT3 protein, expressed by HEK293 , with Fc labeled tag. The total length of FITC-Labeled FLT3 Protein, Human (HEK293, Fc) is 517 a.a., with molecular weight of 110-130 kDa & 250 kDa, respectively.

	FLT3 Protein, Human (T227M, HEK293, His) CD135; FL cytokine receptor; FLK2; Flk-2; FLT-3; STK-1	Human	HEK293
	FLT3, a tyrosine-protein kinase receptor, regulates hematopoietic progenitor cells and dendritic cells' differentiation, proliferation, and survival. It phosphorylates downstream effectors like SHC1 and AKT1, activating signaling cascades involving MTOR, RAS, and MAP kinases. Additionally, it plays a pivotal role in the phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A/B. Wild-type FLT3 activation modestly activates STAT5A or STAT5B, while constitutive kinase mutations heighten cell proliferation and resist apoptosis, highlighting its role in fostering aberrant signaling pathways. FLT3 Protein, Human (T227M, HEK293, His) is the recombinant human-derived FLT3 protein, expressed by HEK293 , with C-His labeled tag and T227M mutation. The total length of FLT3 Protein, Human (T227M, HEK293, His) is 515 a.a., with molecular weight of 85-95 kDa.

	FLT3 Protein, Human (T227M, HEK293, hFc) CD135; FL cytokine receptor; FLK2; Flk-2; FLT-3; STK-1	Human	HEK293
	FLT3 is a tyrosine-protein kinase receptor that regulates differentiation, proliferation, and survival of hematopoietic progenitor cells and dendritic cells. It phosphorylates downstream effectors such as SHC1 and AKT1, activating signaling cascades involving MTOR, RAS, and MAP kinases. FLT3 Protein, Human (T227M, HEK293, hFc) is the recombinant human-derived FLT3 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of FLT3 Protein, Human (T227M, HEK293, hFc) is 517 a.a., with molecular weight of 100-145 kDa.

	FLT3 Protein, Human (Biotinylated, sf9, His) FLT3; fms-related tyrosine kinase 3; receptor-type tyrosine-protein kinase FLT3; CD135; FLK2; STK1; STK-1; CD135 antigen; FL cytokine receptor; fetal liver kinase 2; fms-like tyrosine kinase 3; stem cell tyrosine kinase 1; growth factor receptor tyrosine kinase type III; FLK-2	Human	Sf9 insect cells

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