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Results for "

FZD7

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

4

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P1454
    Fz7-21
    3 Publications Verification

    Ac-LPSDDLEFWCHVMY-NH2

    		 Wnt Cancer
    Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) is a potent peptide antagonist of FZD7 receptors , selectively binds to FZD7 CRD subclass and alters the conformation of the CRD and the architecture of its lipid-binding groove. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively. Fz7-21 impairs the function of FZD7 in Wnt–β-catenin signalling and stem cell function in intestinal organoids .
    Fz<em>7</em>-21
  • HY-P1454A
    Fz7-21 TFA
    3 Publications Verification

    Ac-LPSDDLEFWCHVMY-NH2 TFA

    		 Wnt Cancer
    Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) TFA is a potent peptide antagonist of FZD7 receptors , selectively binds to FZD7 CRD subclass and alters the conformation of the CRD and the architecture of its lipid-binding groove. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively. Fz7-21 TFA impairs the function of FZD7 in Wnt-β-catenin signalling and stem cell function in intestinal organoids .
    Fz<em>7</em>-21 TFA
  • HY-P10204
    FZD7 antagonist 1

    		Wnt Cancer
    FZD7 antagonist 1 (peptide 34) is a dFz7-21 analogue. FZD7 antagonist 1 is an FZD7 antagonist that inhibits the wnt3a with IC50 value of 9.2 nM. FZD7 antagonist 1 blocks TcdB−FZD interaction via targeting FZD receptors .
    <em>FZD7</em> antagonist 1
  • HY-RS05183
    FZD7 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others
    FZD7 Human Pre-designed siRNA Set A contains three designed siRNAs for FZD7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    FZD7 Human Pre-designed siRNA Set A
    FZD7 Human Pre-designed siRNA Set A
  • HY-156095
    F7H

    		Wnt Cancer
    F7H is a Frizzled receptor FZD7 antagonist (IC50: 1.25 μM). Frizzled receptors (FZDs) influence Wnt signaling, mediating embryonic development and tissue homeostasis. F7H is a potent ligand for the FZD7 transmembrane domain (TMD) .
    F<em>7</em>H
  • HY-117002
    SRI 37892

    		Others Cancer
    SRI 37892 is a small molecule compound inhibitor of Frizzled protein 7 (Fzd7) with inhibitory activity against cancer cell proliferation (IC502μM). SRI 37892 significantly blocks Wnt/Fzd7 signaling. SRI 3789 can be used in the research of developing cancer therapeutic agents [1].
    SRI 37892
  • HY-P1454B
    Fz7-21S

    		Wnt Cancer
    Fz7-21S is a negative control of Fz7-21. Fz7-21 is a potent peptide antagonist of FZD7 receptors .
    Fz<em>7</em>-21S

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