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Ferrostatin-1

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100579
    Ferrostatin-1
    520+ Cited Publications

    Fer-1

    		 Ferroptosis Fungal Cancer
    Ferrostatin-1 (Fer-1), a potent and selective ferroptosis inhibitor, suppresses Erastin-induced ferroptosis in HT-1080 cells (EC50=60 nM). Ferrostatin-1, a synthetic antioxidant, acts via a reductive mechanism to prevent damage to membrane lipids and thereby inhibits cell death. Ferrostatin-1 exhibits antifungal activity [1] .
    <em>Ferrostatin-1</em>
  • HY-116087
    SRS11-92

    		Ferroptosis Neurological Disease Cancer
    SRS11-92, a Ferrostatin-1 (Fer-1) analogue, is a potent ferroptosis inhibitor. SRS11-92 inhibits ferroptotic cell death induced by Erastin in HT-1080 human fibrosarcoma cells (EC50=6 nM) [1].
    SRS11-92
  • HY-135430
    SRS16-86

    		Ferroptosis Inflammation/Immunology
    SRS16-86 is a potent inhibitor of ferroptosis [1]. SRS16-86 is more stable than more stable to metabolism and plasma than Ferrostatin-1 in vivo. SRS16-86 can be used for renal ischemia-reperfusion injury (IRI) and spinal cord injury (SCI) research .
    SRS16-86
  • HY-163074
    Ferroptosis-IN-6

    		Ferroptosis Cancer
    Ferroptosis-IN-6 (compound 13) is a potent inhibitor of Ferroptosis with EC50 of 25.5 nM. Ferroptosis-IN-6 significantly inhibits RSL3-induced cell death in cells and in vivo [1].
    Ferroptosis-IN-6

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