Forsythia suspensa

By Targets:	Bacterial (1) Cytochrome P450 (1) Influenza Virus (1) NF-κB (1) TNF Receptor (1)
By Research Areas:	Cancer (1) Infection (1) Inflammation/Immunology (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0029

Forsythoside B 5 Publications Verification	TNF Receptor NF-κB	Inflammation/Immunology
Forsythoside B is a phenylethanoid glycoside isolated from Forsythia suspensa (Thunb.) Vahl, a Chinese folk medicinal plant for treating inflammatory diseases and promoting blood circulation. Forsythoside B could inhibit TNF-alpha, IL-6, IκB and modulate NF-κB.

HY-N0482

Phillyrin 1 Publications Verification	Cytochrome P450 Influenza Virus Bacterial	Infection Inflammation/Immunology Cancer
Phillyrin is isolated from Forsythia suspensa Vahl (Oleaceae), has antibacterial and anti-inflammatory activities. Phillyrin has potential inductive effects on rat CYP1A2 and CYP2D1 activities, without affecting CYP2C11 and CYP3A1/2 activities . Phillyrin has anti-influenza A virus activities .

HY-N0028

Forsythiaside A 1 Publications Verification	Others	Inflammation/Immunology
Forsythiaside A is an orally active phenylethanoid glycoside isolated from the dried fruits of Forsythia suspensa. Forsythiaside A is also an inhibitor of COX-2 and has anti-inflammatory, antioxidant and neuroprotective effects. Forsythiaside A prevents neuroinflammation and apoptosis caused by Aβ_25-35 damage and may be used in Alzheimer's disease (AD) research. Forsythiaside A also activates the Nrf2/HO-1 signaling pathway and inhibits OVA-induced asthma in mice .

HY-N8021

Epipinoresinol-4-O-β-glucoside (+)-Epipinoresinol-4′′-β-D-glucoside	Others	Others
Epipinoresinol-4-O-β-glucoside (Compound 3) is a lignan glucoside that can be isolated from Forsythia suspensa .

HY-N1522

Rengynic acid

Others Others

Rengynic acid can be isolated from the seeds of Forsythia suspensa. Rengynic acid has potent antiviral effect on RSV .

Rengynic acid	Others	Others
Rengynic acid can be isolated from the seeds of Forsythia suspensa. Rengynic acid has potent antiviral effect on RSV .

Cat. No.	Product Name

HY-L114

Anti-inflammatory Traditional Chinese Medicine Active Compound Library	1057 compounds
Inflammation promotes physiological and pathological processes by the activation of the immune system, local vascular system, and various cells within the damaged tissue. Accumulating epidemiological and clinical evidence shows that chronic inflammation is causally linked to various human diseases, including cerebrovascular, cardiovascular, joint, cutaneous, pulmonary, blood, liver, and intestinal diseases as well as diabetes. Various natural products from Traditional Chinese Medicine (TCM) have been shown to safely suppress proinflammatory pathways and control inflammation-associated disease. MCE designs a unique collection of 1057 Traditional Chinese Medicine active compounds with anti-inflammatory activity, which are derived from Coptis chinensis, Radix isatidis, Flos Lonicerae, Forsythia suspensa, etc. MCE Anti-inflammatory Traditional Chinese Medicine Active Compound Library is a useful tool for discovery anti-inflammatory drugs from TCM.

Anti-inflammatory Traditional Chinese Medicine Active Compound Library

1057 compounds

Inflammation promotes physiological and pathological processes by the activation of the immune system, local vascular system, and various cells within the damaged tissue. Accumulating epidemiological and clinical evidence shows that chronic inflammation is causally linked to various human diseases, including cerebrovascular, cardiovascular, joint, cutaneous, pulmonary, blood, liver, and intestinal diseases as well as diabetes.

Various natural products from Traditional Chinese Medicine (TCM) have been shown to safely suppress proinflammatory pathways and control inflammation-associated disease. MCE designs a unique collection of 1057 Traditional Chinese Medicine active compounds with anti-inflammatory activity, which are derived from Coptis chinensis, Radix isatidis, Flos Lonicerae, Forsythia suspensa, etc. MCE Anti-inflammatory Traditional Chinese Medicine Active Compound Library is a useful tool for discovery anti-inflammatory drugs from TCM.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0029

Forsythoside B 5 Publications Verification	Structural Classification Classification of Application Fields Oleaceae Simple Phenylpropanols Source classification Phenols Polyphenols Phenylpropanoids Plants Forsythia suspensa (Thunb.) Vahl Inflammation/Immunology Disease Research Fields	TNF Receptor NF-κB
Forsythoside B is a phenylethanoid glycoside isolated from Forsythia suspensa (Thunb.) Vahl, a Chinese folk medicinal plant for treating inflammatory diseases and promoting blood circulation. Forsythoside B could inhibit TNF-alpha, IL-6, IκB and modulate NF-κB.

HY-N0482

Phillyrin 1 Publications Verification	Infection Classification of Application Fields Oleaceae Source classification Lignans Phenylpropanoids Plants Forsythia suspensa (Thunb.) Vahl Inflammation/Immunology Disease Research Fields	Cytochrome P450 Influenza Virus Bacterial
Phillyrin is isolated from Forsythia suspensa Vahl (Oleaceae), has antibacterial and anti-inflammatory activities. Phillyrin has potential inductive effects on rat CYP1A2 and CYP2D1 activities, without affecting CYP2C11 and CYP3A1/2 activities . Phillyrin has anti-influenza A virus activities .

HY-N0028

Forsythiaside A 1 Publications Verification	Structural Classification Classification of Application Fields Oleaceae Simple Phenylpropanols Source classification Phenols Polyphenols Phenylpropanoids Plants Forsythia suspensa (Thunb.) Vahl Inflammation/Immunology Disease Research Fields	Others
Forsythiaside A is an orally active phenylethanoid glycoside isolated from the dried fruits of Forsythia suspensa. Forsythiaside A is also an inhibitor of COX-2 and has anti-inflammatory, antioxidant and neuroprotective effects. Forsythiaside A prevents neuroinflammation and apoptosis caused by Aβ_25-35 damage and may be used in Alzheimer's disease (AD) research. Forsythiaside A also activates the Nrf2/HO-1 signaling pathway and inhibits OVA-induced asthma in mice .

HY-N8021

Epipinoresinol-4-O-β-glucoside (+)-Epipinoresinol-4′′-β-D-glucoside	Structural Classification Oleaceae Source classification Lignans Phenylpropanoids Forsythia suspensa (Thunb.) Vahl Plants	Others
Epipinoresinol-4-O-β-glucoside (Compound 3) is a lignan glucoside that can be isolated from Forsythia suspensa .

HY-N1522

Rengynic acid	Structural Classification Oleaceae Ketones, Aldehydes, Acids Source classification Plants Forsythia suspensa (Thunb.) Vahl	Others
Rengynic acid can be isolated from the seeds of Forsythia suspensa. Rengynic acid has potent antiviral effect on RSV .

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Forsythia suspensa

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