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Results for "

GDC-0927

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-111484
    GDC-0927
    3 Publications Verification

    SRN-927

    		 Estrogen Receptor/ERR Cancer
    GDC-0927 (SRN-927) is a potent, non-steroidal, orally bioavailable, selective estrogen receptor antagonist .
    <em>GDC-0927</em>
  • HY-120207
    (R)-GDC-0927

    (R)-SRN-927

    		 Others Others
    (R)-GDC-0927 ((R)-SRN-927) is a (R)-enantiomer of GDC-0927 (HY-111484) .
    (R)-<em>GDC-0927</em>
  • HY-141551
    GNE-274

    		Estrogen Receptor/ERR Cancer
    GNE-274 is a non-degrader that is structurally related to GDC-0927 (ER degrader). GNE-274 does not induce ER turnover and functions as a partial ER agonist in breast cancer cell lines. GNE-274 increase chromatin accessibility at ER-DNA binding sites, while GDC-0927 do not. GNE-274 is a potent inhibitor of ER-ligand binding domain (LBD). GNE-274 can be used for cancer research .
    GNE-274
  • HY-111484A
    GDC-0927 Racemate

    SRN-927 Racemate

    		 Estrogen Receptor/ERR Cancer
    GDC-0927 Racemate (SRN-927 Racemate) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases.
    <em>GDC-0927</em> Racemate
  • HY-141551B
    (R)-GNE-274

    		Others Others
    (R)-GNE-274 is a enantiomer of GNE-274. GNE-274 is a non-degrader that is structurally related to GDC-0927 (estrogen receptor degrader) .
    (R)-GNE-274

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