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Results for "

Glycyrrhizin

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

5

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0184
    Glycyrrhizic acid
    20+ Cited Publications

    Glycyrrhizin

    		 Virus Protease Metabolic Disease Cancer
    Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities.
    Glycyrrhizic acid
  • HY-N11111
    Glycyrrhizin-6'-methylester

    		Others Others
    Glycyrrhizin-6'-methylester is a natural product that can be isolated from licorice (Glycyrrhiza glabra) .
    <em>Glycyrrhizin</em>-6'-methylester
  • HY-N6851
    Glycyrrhetic acid 3-O-β-D-glucuronide

    Glycyrrhetic acid 3-O-mono-β-D-glucuronide; 3-monoglucuronyl-glycyrrhetinic acid

    		 Others Inflammation/Immunology
    Glycyrrhetic acid 3-O-β-D-glucuronide, isolated from glycyrrhiza, is an important derivative of glycyrrhizin (GL) with an anti -allergic activity . Glycyrrhetic acid 3-O-β-D-glucuronide (GAMG) shows that β-glucuronidases (β-GUS) are key GAMG-producing enzymes, displaying a high potential to convert GL directly into GAMG .Glycyrrhetic acid 3-O-β-D-glucuronide is valuable as a sweetener.
    Glycyrrhetic acid 3-O-β-D-glucuronide
  • HY-N11976
    Glycyrrhizin-6′′-methylester

    		Others Others
    Glycyrrhizin-6′′-methylester (compound 22) is a glycyrrhizin that can be isolated from licorice root. Glycyrrhizin-6′′-methylester can participate as an aglycone in the formation of methyl glucuronate, producing a sweet and licorice taste, but no bitterness. This reveals the importance of the free carboxyl group on the glycoside cone-bound glucuronic acid for natural sweetness and licorice taste .
    <em>Glycyrrhizin</em>-6′′-methylester
  • HY-N11975
    Glycyrrhizin-6′,6′′-dimethylester

    		Others Others
    Glycyrrhizin-6′,6′′-dimethylester (compound 23) is a licorice saponin isolated from licorice root. Glycyrrhizin-6′,6′′-dimethylester can participate as an aglycone in the generation of methyl glucuronate, producing similar threshold sweetness, licorice, and bitterness .
    <em>Glycyrrhizin</em>-6′,6′′-dimethylester
  • HY-155759
    HMGB1-IN-2

    		Others Inflammation/Immunology Cancer
    HMGB1-IN-2 (compound 15) is an inhibitor of highly conserved nuclear protein (HMGB1), showing NO inhibitory effect with IC50 value of 20.2 μM in RAW264.7 cells. HMGB1-IN-2 (30 μM) decreases the level of IL-1 β, TNF-α, caspase-1 p20, inhibits the phosphorylation of NF-κB p65, exhibits anti-apoptotic activity. HMGB1-IN-2 (15 mg/kg; ip) relives kidney injury in septic acute kidney injury mouse. HMGB1-IN-2 inhibits Huh7 cells and A549 cells with IC50s of 77.0 μM, and 82.0 μM, respectively .
    HMGB1-IN-2

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