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Results for "

H2S

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Bacterial (2) Biochemical Assay Reagents (1) Calcium Channel (1) COX (1) Endogenous Metabolite (11) Fluorescent Dye (6) Hippo (MST) (1) Isotope-Labeled Compounds (3) mAChR (1) MDM-2/p53 (1) NF-κB (1) Reactive Oxygen Species (1) STAT (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (4) Infection (2) Inflammation/Immunology (6) Metabolic Disease (11) Neurological Disease (6)
Click Chemistry:	Azide (2) Alkynes (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-130347

H2S Donor 5a	Endogenous Metabolite	Others
H2S Donor 5a is a cysteine-activated H2S donor. H₂S plays important roles in biological systems. H2S Donor 5a is a useful tool in H₂S research .

HY-124409

WSP-1

Fluorescent Dye Others

WSP-1 is a selective and rapid-reaction H₂S specific fluorescent dye (Ex/Em=465/515 nm). WSP-1 reacts with H₂S with the releasing of fluorophore .

WSP-1	Fluorescent Dye	Others
WSP-1 is a selective and rapid-reaction H₂S specific fluorescent dye (Ex/Em=465/515 nm). WSP-1 reacts with H₂S with the releasing of fluorophore .

HY-D1275

CAY10731	Fluorescent Dye	Others
CAY10731 (compound 3) is a highly selective fluorescent probe for detection of hydrogen sulfide (H₂S). CAY10731 is used to monitor exo- and endogenous H₂S in both cancer and normal cells. CAY10731 is applied for imaging of H₂S in living tissues at variable depths and in nematodes .

HY-134495

N-Acetyl-L-cysteine ethyl ester 3 Publications Verification N-Acetylcysteine ethyl ester; NACET	Reactive Oxygen Species	Metabolic Disease
N-Acetyl-L-cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC). N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H₂S) and can be used as an H₂S producer. N-Acetyl-L-cysteine ethyl ester has the potential to substitute NAC as a mucolytic agent, and as a GSH-related antioxidant .

HY-D1400

HBTP-H2S chloride

Fluorescent Dye Others

HBTP-H2S (chloride) is a NIR fluorescent probe for in situ bioimaging of endogenous H2S in rice roots under Al ³⁺ and flooding stresses.
HY-160240

HPI

Others Others

HPI is a HS ^- fluorescent probe (Ex/Em=280/410 nm). HPI can be used to detect the HS ^- form of hydrogen sulfide (H₂S) gas in environmental water samples .

HBTP-H2S chloride	Fluorescent Dye	Others
HBTP-H2S (chloride) is a NIR fluorescent probe for in situ bioimaging of endogenous H2S in rice roots under Al ³⁺ and flooding stresses.

HPI	Others	Others
HPI is a HS ^- fluorescent probe (Ex/Em=280/410 nm). HPI can be used to detect the HS ^- form of hydrogen sulfide (H₂S) gas in environmental water samples .

HY-126124

AP39 2 Publications Verification	Others	Cardiovascular Disease Neurological Disease
AP39 is a triphenylphosphonium derivatised anethole dithiolethione and mitochondria-targeting hydrogen sulfide (H₂S) donor. AP39 increases intracellular H₂S levels. AP39 exerts cytoprotective effects and maintains mitochondrial DNA integrity under oxidative stress conditions. AP39 protects against myocardial reperfusion injury in mice model and has the potential for Alzheimer's disease research ^[2] .

HY-107632

GYY4137 3 Publications Verification	Others	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
GYY4137 is a slow releasing H2S donor with vasodilator and antihypertensive activity. GYY4137 also exhibits anti-inflammatory and anticancer activity ^[2] .

HY-144439

HTS07545	Others	Cardiovascular Disease
HTS07545 is a potent sulfide:quinone oxidoreductase (SQOR) inhibitor with an IC₅₀ of 30 nM. HTS07545 decrease the rate of breakdown of hydrogen sulfide (H2S). HTS07545 can be used for heart failure research .

HY-129420

WSP-5	Fluorescent Dye	Others
WSP-5 is a fluorescent probe for fast detection of H₂S in biological samples and cells. WSP-5 selectively and rapidly reacts with H₂S and exhibits fluorescence through a reaction-based fluorescent turn-on strategy.

HY-149837

PRO-F	Fluorescent Dye	Inflammation/Immunology
PRO-F is a photoactivable H₂S donor with ROS scavenging ability. PRO-F can be activated by light to produce fluorescent signal, for real-time tracking of released H₂S. PRO-F activation doesn’t consume endogenous substances. deliver H₂S in an intracellular environment to protect cells from excessive reactive oxygen species (ROS) induced damage. PRO-F shows enhancement on chronic wound healing, researched in diabetic models as well .

HY-15033

ATB-343	Others	Infection Inflammation/Immunology
ATB-343 is a derivative of Indomethacin that releases H2S. H2S has cytoprotective and anti-inflammatory effects, inhibiting leukocyte adhesion to vascular endothelium and leukocyte migration to inflammatory sites. ATB-343 can be used to suppress respiratory infections ^[2].

HY-121955

FW1256 1 Publications Verification	NF-κB Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
FW1256 is a phenyl analogue and a slow-releasing hydrogen sulfide (H₂S) donor. FW1256 inhibits NF-κB activity and induces cell apoptosis. FW1256 exerts potent anti-inflammatory effects and has the potential for cancer and cardiovascular disease treatment ^[2].

HY-W018555

D-Cysteine	Endogenous Metabolite Bacterial	Infection Neurological Disease
D-Cysteine is the D-isomer of cysteine and a powerful inhibitor of *Escherichia coli* growth. D-cysteine is mediated by D-amino acid oxidase to produce H₂S and is a neuroprotectant against cerebellar ataxias. D-Cysteine could inhibit the growth and cariogenic virulence of dual-species biofilms formed by *S. mutans* and *S. sanguinis* ^[2] .

HY-15035

S-Diclofenac ACS 15; ATB-337	COX	Inflammation/Immunology
S-Diclofenac is a hybrid molecule of an H₂S donor and the NSAID diclofenac. S-Diclofenac spares the gastric mucosa of injury despite markedly suppressing prostaglandin synthesis .

HY-E70078

Cystathionine β-synthase	Biochemical Assay Reagents	Others
Cystathionine β-synthase is an enzyme that catalyzes the condensation of serine and homocysteine to water and cystathionine. Cystathionine β-synthase is a prominent enzyme for the production of hydrogen sulfide (H₂S) .

HY-Y0337

L-Cysteine 3 Publications Verification Cysteine
L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans .

HY-Y0337A

L-Cysteine hydrochloride 3 Publications Verification
L-Cysteine hydrochloride is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents and humans .

HY-W016715

L-Cysteine hydrochloride hydrate 3 Publications Verification	Endogenous Metabolite	Metabolic Disease
L-Cysteine hydrochloride hydrate is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride hydrate suppresses ghrelin and reduces appetite in rodents and humans .

HY-Y0337S5

L-Cysteine-d3	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Cysteine-d₃ is the deuterium labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S6

L-Cysteine-d2	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Cysteine-d₂ is the deuterium labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S1

L-Cysteine-15N	Endogenous Metabolite	Metabolic Disease
L-Cysteine- ¹⁵N is the ¹⁵N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S4

L-Cysteine-13C3	Endogenous Metabolite	Metabolic Disease
L-Cysteine- ¹³C₃ is the ¹³C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S2

L-Cysteine-3-13C	Endogenous Metabolite	Metabolic Disease
L-Cysteine-3- ¹³C is the ¹³C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S3

L-Cysteine-1-13C	Endogenous Metabolite	Metabolic Disease
L-Cysteine-1- ¹³C is the ¹³C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S

L-Cysteine-13C3,15N	Endogenous Metabolite	Metabolic Disease
L-Cysteine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S7

L-Cysteine-d3,15N	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Cysteine-d₃, ¹⁵N is the deuterium and ¹⁵N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-110128

Sulfidefluor 7-AM SF7-AM	Fluorescent Dye	Others
Sulfidefluor 7-AM is a stable hydrogen sulphide (H₂S) fluorescent probe . Sulfidefluor 7-AM is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-W001538

S-Propargylcysteine SPRC	STAT MDM-2/p53	Inflammation/Immunology
S-Propargylcysteine (SPRC), a structural analog of S-allyl cysteine (SAC), is a slow H₂S-releasing compound. S-Propargylcysteine reduces Ca ²⁺ accumulation and inflammatory cytokines, inhibits STAT3, and elevates p53 and Bax. S-Propargylcysteine has anti-inflammatory activity and protects mice against acute pancreatitis. S-Propargylcysteine also has cardioprotective, neuroprotective acitivties ^[2].

HY-128206

I3MT-3 4 Publications Verification HMPSNE	Hippo (MST)	Metabolic Disease
I3MT-3 (HMPSNE) is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC₅₀=2.7 μM). I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes. I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST .

HY-106784A

(E)-Ajoene	Others	Neurological Disease
(E)-Ajoene is a oxygenated ajoene and organosulfur compound, which can be acquired via allicin decomposing. The polysulfides from garlic can be converted by human red blood cells into hydrogen sulfide (H2S) and allyl glutathione. (E)-Ajoene has been proved to show neuroprotective effects against ischemic damage. (E)-Ajoene is orally active to inhibit lipid peroxidation. (E)-Ajoene increases the number of cresyl violet-positive neurons and decreases the number of reactive gliosis in the CA1 region ^[2].

HY-W103170

1,8-Dichloroanthraquinone

Bacterial Others

1,8-Dichloroanthraquinone, an anthraquinone, is an inhibitor of sulfide production by sulfate-reducing bacteria .

1,8-Dichloroanthraquinone	Bacterial	Others
1,8-Dichloroanthraquinone, an anthraquinone, is an inhibitor of sulfide production by sulfate-reducing bacteria .

HY-B1223

Anethole trithione 1 Publications Verification	mAChR	Neurological Disease Cancer
Anethole trithione, a sulfur heterocyclic choleretic, is a bile secretion-stimulating agent. Anethole trithione enhances salivary secretion and increases mAChRs, and can be used for dry mouth research ^[2].

HY-115681

(2R/S)-6-PNG 1 Publications Verification 6-Prenylnaringenin; (±)-6-Prenylnaringenin	Calcium Channel	Neurological Disease
(2R/S)-6-PNG (6-Prenylnaringenin) is a potent and reversible Ca_v3.2 T-type Ca ²⁺ channels (T-channels) blocker. (2R/S)-6-PNG can penetrate the blood-brain barrier (BBB). (2R/S)-6-PNG suppresses neuropathic and visceral pain in mice .

WSP-1	Fluorescent Dyes/Probes
WSP-1 is a selective and rapid-reaction H₂S specific fluorescent dye (Ex/Em=465/515 nm). WSP-1 reacts with H₂S with the releasing of fluorophore .

CAY10731	Fluorescent Dyes/Probes
CAY10731 (compound 3) is a highly selective fluorescent probe for detection of hydrogen sulfide (H₂S). CAY10731 is used to monitor exo- and endogenous H₂S in both cancer and normal cells. CAY10731 is applied for imaging of H₂S in living tissues at variable depths and in nematodes .

WSP-5	Fluorescent Dyes/Probes
WSP-5 is a fluorescent probe for fast detection of H₂S in biological samples and cells. WSP-5 selectively and rapidly reacts with H₂S and exhibits fluorescence through a reaction-based fluorescent turn-on strategy.

Cystathionine β-synthase	Biochemical Assay Reagents
Cystathionine β-synthase is an enzyme that catalyzes the condensation of serine and homocysteine to water and cystathionine. Cystathionine β-synthase is a prominent enzyme for the production of hydrogen sulfide (H₂S) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-130347

H2S Donor 5a	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
H2S Donor 5a is a cysteine-activated H2S donor. H₂S plays important roles in biological systems. H2S Donor 5a is a useful tool in H₂S research .

HY-W018555

D-Cysteine	Human Gut Microbiota Metabolites Microorganisms Source classification Amino acids Endogenous metabolite	Endogenous Metabolite Bacterial
D-Cysteine is the D-isomer of cysteine and a powerful inhibitor of *Escherichia coli* growth. D-cysteine is mediated by D-amino acid oxidase to produce H₂S and is a neuroprotectant against cerebellar ataxias. D-Cysteine could inhibit the growth and cariogenic virulence of dual-species biofilms formed by *S. mutans* and *S. sanguinis* ^[2] .

HY-W016715

L-Cysteine hydrochloride hydrate 3 Publications Verification	Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Cysteine hydrochloride hydrate is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride hydrate suppresses ghrelin and reduces appetite in rodents and humans .

HY-B1223

Anethole trithione 1 Publications Verification	Structural Classification Natural Products Leguminosae Source classification Sophora alopecuroides L Plants	mAChR
Anethole trithione, a sulfur heterocyclic choleretic, is a bile secretion-stimulating agent. Anethole trithione enhances salivary secretion and increases mAChRs, and can be used for dry mouth research ^[2].

HY-106784A

(E)-Ajoene	Structural Classification Natural Products Source classification Allium sativum L. Plants Amaryllidaceae	Others
(E)-Ajoene is a oxygenated ajoene and organosulfur compound, which can be acquired via allicin decomposing. The polysulfides from garlic can be converted by human red blood cells into hydrogen sulfide (H2S) and allyl glutathione. (E)-Ajoene has been proved to show neuroprotective effects against ischemic damage. (E)-Ajoene is orally active to inhibit lipid peroxidation. (E)-Ajoene increases the number of cresyl violet-positive neurons and decreases the number of reactive gliosis in the CA1 region ^[2].

Cat. No.	Product Name	Chemical Structure

HY-Y0337S5

L-Cysteine-d3
L-Cysteine-d₃ is the deuterium labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S6

L-Cysteine-d2
L-Cysteine-d₂ is the deuterium labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S1

L-Cysteine-15N
L-Cysteine- ¹⁵N is the ¹⁵N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S4

L-Cysteine-13C3
L-Cysteine- ¹³C₃ is the ¹³C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S2

L-Cysteine-3-13C
L-Cysteine-3- ¹³C is the ¹³C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S3

L-Cysteine-1-13C
L-Cysteine-1- ¹³C is the ¹³C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S

L-Cysteine-13C3,15N
L-Cysteine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S7

L-Cysteine-d3,15N
L-Cysteine-d₃, ¹⁵N is the deuterium and ¹⁵N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

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H2S

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Click Chemistry

Natural
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