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Results for "

HL2/3

" in MedChemExpress (MCE) Product Catalog:

By Targets:	HDAC (1)
By Research Areas:	Cancer (1)

1

Inhibitors & Agonists

3

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*HL23*	HDAC	Cancer
HL23 is a histone deacetylase (HDAC) inhibitor with activity against hepatocellular carcinoma (HCC). HL23 enhances acetylation of the TXNIP promoter and upregulates TXNIP expression, thereby mediating potassium channel activity and triggering TXNIP-dependent potassium deprivation. HL23 inhibits HCC progression and metastasis and has a synergistic effect with Sorafenib (HY-10201) and is more potent than Sorafenib+Vorinostat (HY-10221) .

Species:	Human (1) Rat (1) Mouse (1)
Tag:	His (3) SUMO (1)
Source:	HEK293 (1) E. coli Cell-free (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

	ASGR2 Protein, Human (HEK293, His) Asgr2; Asgr-2; Asialoglycoprotein receptor 2; ASGP-R 2; ASGPR 2; Hepatic lectin 2; HL-2; mHL-2	Human	HEK293
	ASGR2 mediates endocytosis of desialylated glycoproteins, recognizing galactose and N-acetylgalactosamine units. Ligand binding leads to internalization and sorting organelle transport, followed by receptor return to the cell membrane. The receptor is suggested to function as a dimer. ASGR2 also interacts with LASS2. ASGR2 Protein, Human (HEK293, His) is the recombinant human-derived ASGR2 protein, expressed by HEK293 , with N-His labeled tag. The total length of ASGR2 Protein, Human (HEK293, His) is 232 a.a., with molecular weight of 37-42 kDa.

	ASGR2 Protein, Rat (Cell-Free, His) Asialoglycoprotein receptor 2; Hepatic lectin R2/3; HL-2; rHL-2	Rat	E. coli Cell-free
	The ASGR2 protein plays a key role in cellular processes by mediating the endocytosis of desialylated plasma glycoproteins and recognizing terminal galactose and N-acetylgalactosamine. It promotes ligand internalization and formation of complexes that are transported to sorting organelles. ASGR2 Protein, Rat (Cell-Free, His) is the recombinant rat-derived ASGR2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of ASGR2 Protein, Rat (Cell-Free, His) is 301 a.a., with molecular weight of 41.1 kDa.

	ASGR2/ASGPR2 Protein, Mouse (His-SUMO) Asgr2; Asgr-2; Asialoglycoprotein receptor 2; ASGP-R 2; ASGPR 2; Hepatic lectin 2; HL-2; mHL-2	Mouse	E. coli
	ASGR2/ASGPR2 proteins are critical in cellular processes, mediating the endocytosis of desialylated plasma glycoproteins. It recognizes terminal galactose and N-acetylgalactosamine, promotes ligand internalization, and forms complexes that are transported to sorting organelles. ASGR2/ASGPR2 Protein, Mouse (His-SUMO) is the recombinant mouse-derived ASGR2/ASGPR2 protein, expressed by E. coli , with N-10*His, N-SUMO labeled tag. The total length of ASGR2/ASGPR2 Protein, Mouse (His-SUMO) is 222 a.a., with molecular weight of ~45.9 kDa.

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