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" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-151359

    Apoptosis HSP Cancer
    Hsp90-IN-16 (compound 16s) is an HSP90 inhibitor with high selectivity and potency against HER2-positive cancer cells. Hsp90-IN-16 exhibits high anti-proliferative capacity against HCC1954 breast cancer cells with an IC50 of 6 μM. Hsp90-IN-16 induces apoptosis by inhibiting HSP90 "client" proteins, including a key oncogenic receptor, HER2/neu.