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IL-5R

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Interleukin Related (3) Apoptosis (1)
By Research Areas:	Cancer (1) Inflammation/Immunology (3)

3

Inhibitors & Agonists

2

Inhibitory Antibodies

6

Recombinant Proteins

1

Antibodies

Targets Recommended: Interleukin Related IRAK Itk

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

YM-90709 1 Publications Verification	Interleukin Related	Inflammation/Immunology
YM-90709 is a novel *IL-5* inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).YM-90709 potently inhibits the binding of [ ¹²⁵I]-IL-5 to IL-5R on human peripheral eosinophils and eosinophilic HL-60 clone 15 cells with IC₅₀ values of 1.0 and 0.57 μM .

Benralizumab MEDI-563; BIW-8405	Interleukin Related Apoptosis	Inflammation/Immunology Cancer
Benralizumab (MEDI-563) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma .

Benralizumab (anti-IL5RA ) MEDI-563 (anti-IL5RA ); BIW-8405 (anti-IL5RA )	Interleukin Related	Inflammation/Immunology
Benralizumab (anti-IL5RA ) (MEDI-563 (anti-IL5RA ); BIW-8405 (anti-IL5RA )) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma study .

Species:	Human (4) Mouse (2)
Tag:	His (6) Avi (2)
Source:	HEK293 (5) Sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source

	IL-5R alpha Protein, Human (Biotinylated, HEK293, His-Avi) CD125; CDw125CD125; HSIL5R3; IL-5 R alpha; IL-5R subunit alpha; IL5R; IL5RA; IL-5Ra; MGC26560	Human	HEK293
	IL-5R alpha protein is a cytokine receptor that is expressed on eosinophils, basophils and B cells and is involved in inflammation and immune regulation.IL-5R alpha Protein, Human (Biotinylated, HEK293, His-Avi) is expressed by HEK293 cells and is a transmembrane protein (F343-C362) with His-Avi tags.

	IL-5R alpha Protein, Human (HEK293, His) Interleukin-5 receptor subunit alpha; IL-5R-alpha; IL-5RA; CDw125; CD125; IL5R	Human	HEK293
	IL-5R alpha protein is a cytokine receptor that is expressed on eosinophils, basophils and B cells and is involved in inflammation and immune regulation.IL-5R alpha Protein, Human (HEK293, His) is expressed by HEK293 cells with a C-6*His tag.

	IL-5R alpha Protein, Mouse (HEK293, His) Interleukin-5 receptor subunit alpha; IL-5R-alpha; IL-5RA; CDw125; CD125; IL5R	Mouse	HEK293
	IL-5R alpha protein is a cytokine receptor that is expressed on eosinophils, basophils and B cells and is involved in inflammation and immune regulation. IL-5R alpha Protein, Mouse (HEK293, His) is expressed by HEK293 cells and is a transmembrane protein (L340-C361) with a C-6*His tag.

	IL-5R alpha Protein, Mouse (sf9, His) Interleukin-5 receptor subunit alpha; IL-5R-alpha; IL-5RA; CDw125; CD125; IL5R	Mouse	Sf9 insect cells
	IL-5R alpha protein is a cytokine receptor that is expressed on eosinophils, basophils and B cells and is involved in inflammation and immune regulation. IL-5R alpha Protein, Mouse (sf9, His) is expressed by Sf9 insect cells and is a transmembrane protein (L340-C361) with a His tag.

	IL-5R alpha Protein, Human (Q01344-2, HEK293, His) Interleukin-5 receptor subunit alpha; IL-5RA; CD125; IL5R	Human	HEK293
	IL-5R alpha protein is a cytokine receptor that is expressed on eosinophils, basophils and B cells and is involved in inflammation and immune regulation. IL-5R alpha Protein, Human (Q01344-2, HEK293, His) is expressed by HEK293 cells with a C-His tag.

	IL-5R alpha Protein, Human (HEK293, His-Avi) CD125; CDw125CD125; HSIL5R3; IL-5 R alpha; IL-5R subunit alpha; IL5R; IL5RA; IL-5Ra; MGC26560	Human	HEK293
	IL-5R alpha protein is a cytokine receptor that is expressed on eosinophils, basophils and B cells and is involved in inflammation and immune regulation.IL-5R alpha Protein, Human (HEK293, His-Avi) is expressed by HEK293 cells and is a transmembrane protein (F343-C362) with His-Avi tags.

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