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IL10

" in MedChemExpress (MCE) Product Catalog:
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  • HY-P700188AF
    Animal-Free IL-10 Protein, Mouse (His)

    Interleukin-10; IL10; IL-10; Cytokine synthesis inhibitory factor; CSIF

    		 Mouse E. coli
    IL-10 protein is a key immunomodulator that, by binding to its heterotetrameric receptors (IL10RA and IL10RB), activates JAK1 and STAT2 (the latter phosphorylates STAT3), thereby triggering potent anti-inflammatory effects. Phosphorylated STAT3 translocates to the nucleus and promotes the expression of anti-inflammatory mediators. Animal-Free IL-10 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-10 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-10 Protein, Mouse (His) is 160 a.a., with molecular weight of ~19.69 kDa.
  • HY-P70517
    IL-10 Protein, Mouse
    2 Publications Verification

    Interleukin-10; IL10; IL-10; Cytokine synthesis inhibitory factor; CSIF;

    		Mouse E. coli
    IL-10 protein is a key immunomodulator that, by binding to its heterotetrameric receptors (IL10RA and IL10RB), activates JAK1 and STAT2 (the latter phosphorylates STAT3), thereby triggering potent anti-inflammatory effects. Phosphorylated STAT3 translocates to the nucleus and promotes the expression of anti-inflammatory mediators. IL-10 Protein, Mouse is the recombinant mouse-derived IL-10 protein, expressed by E. coli , with tag free. The total length of IL-10 Protein, Mouse is 160 a.a., with molecular weight of 15-17 kDa.
  • HY-P7074A
    IL-10 Protein, Mouse (CHO)

    rMuIL-10; CSIF

    		 Mouse CHO
    IL-10 Protein, Mouse (CHO) is a potent CHO cell derived anti-inflammatory cytokine results in increased immune-mediated demyelination in mice infected with a neurotropic coronavirus.
  • HY-P75825
    IL-10R alpha Protein, Mouse (HEK293, Fc)

    Interleukin-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; CDw210a; Interleukin-10 receptor subunit 1; IL-10R1; CD210; IL10RA

    		 Mouse HEK293
    IL-10R alpha protein is an IL10 cytokine surface receptor that is involved in IL10-mediated inflammation and immune regulation and inhibits the synthesis of pro-inflammatory cytokines. IL-10R alpha Protein, Mouse (HEK293, Fc) is expressed by HEK 293 cells and has a transmembrane region (L242-I262) with a -hFc tag at the C-terminus.
  • HY-P74837
    IL-10R beta Protein, Mouse (HEK293, His)

    Interleukin-10 receptor subunit beta; IL-10RB; CRF2-4; IL-10R2; CDw210b

    		 Mouse HEK293
    IL-10R beta protein is an IL10 cytokine surface receptor involved in IL10-mediated inflammation and immune regulation, as well as viral defense responses. IL-10R beta Protein, Mouse (HEK293, His) is expressed by HEK 293 cells and has a transmembrane region (W223-Y251) with a His tag at the C-terminus.
  • HY-P74838
    IL-10R beta Protein, Mouse (HEK293, hFc)

    Interleukin-10 receptor subunit beta; IL-10RB; CRF2-4; IL-10R2; CDw210b

    		 Mouse HEK293
    IL-10R beta protein is an IL10 cytokine surface receptor involved in IL10-mediated inflammation and immune regulation, as well as viral defense responses. IL-10R beta Protein, Mouse (HEK293, hFc) is expressed by HEK 293 cells and has a transmembrane region (W223-Y251) with a hFc tag at the C-terminus.
  • HY-P77963
    IL-20 Protein, Mouse (HEK293, Fc)

    IL-20; Cytokine Zcyto10; Zcyto10; IL10D; MGC96907

    		 Mouse HEK293
    IL-20 protein is secreted by monocytes and skin keratinocytes and is a proinflammatory cytokine critical for immune responses, inflammatory regulation, hematopoiesis, and epidermal cell differentiation. It enhances tissue remodeling and wound healing, maintaining epithelial integrity during infection. IL-20 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IL-20 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of IL-20 Protein, Mouse (HEK293, Fc) is 152 a.a., with molecular weight of 45-50 kDa.
  • HY-P77964
    IL-20 Protein, Mouse (HEK293, His)

    IL-20; Cytokine Zcyto10; Zcyto10; IL10D; MGC96907

    		 Mouse HEK293
    IL-20 protein is secreted by monocytes and skin keratinocytes and is a proinflammatory cytokine critical for immune responses, inflammatory regulation, hematopoiesis, and epidermal cell differentiation. It enhances tissue remodeling and wound healing, maintaining epithelial integrity during infection. IL-20 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IL-20 protein, expressed by HEK293 , with N-His labeled tag. The total length of IL-20 Protein, Mouse (HEK293, His) is 152 a.a., with molecular weight of 20-22 kDa.
  • HY-P700198AF
    Animal-Free IL-20 Protein, Mouse (His)

    IL-20; Cytokine Zcyto10; Zcyto10; IL10D; MGC96907

    		 Mouse E. coli
    IL-20 Protein, secreted by monocytes and skin keratinocytes, is a pro-inflammatory cytokine crucial for immune responses, inflammatory regulation, hemopoiesis, and epidermal cell differentiation. It enhances tissue remodeling and wound healing, maintaining epithelial integrity during infection. IL-20 Protein impacts actin-mediated functions in neutrophils, inhibiting phagocytosis, granule exocytosis, and migration. It signals through IL20RA/IL20RB or IL22RA1/IL20RB complexes, activating JAK2, STAT5, AKT, and ERK1/2 phosphorylations. In keratinocytes, it activates STAT3 in a JAK2, ERK1/2, and p38 MAPK-dependent manner, forming a heterotrimeric complex with its receptor IL20RA/IL20RB. Animal-Free IL-20 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-20 protein, expressed by E. coli, with C-His labeled tag. The total length of Animal-Free IL-20 Protein, Mouse (His) is 152 a.a., with molecular weight of ~18.52 kDa.

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