1. Search Result
Search Result
Results for "

ITCH Inhibitors

" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-143481
    Nav1.8-IN-2

    Sodium Channel Neurological Disease
    Nav1.8-IN-2 (compound 35A) is a potent Nav1.8 inhibitor with an IC50 value of 0.4 nM. Nav1.8-IN-2 can be used for researching pain disorders, cough disorders, and acute and chronic itch disorders.
  • HY-145153
    S-777469

    Cannabinoid Receptor Neurological Disease
    S-777469 is a selective and orally available cannabinoid type 2 receptor (CB2) agonist with a Ki of 36 nM. S-777469 significantly suppresses compound 48/80-induced scratching behavior in mice in a dose-dependent manner. S-777469 produces its antipruritic effects by inhibiting itch signal transmission through CB2 agonism.