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Results for "

Inhibitor_Kit

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Inhibitory Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P99462

    CDX 0159

    c-Kit Inflammation/Immunology
    Barzolvolimab (CDX 0159) is a humanized anti-KIT IgG1 monoclonal antibody. Barzolvolimab specificity and potently inhibits KIT activation by SCF. Barzolvolimab can reduce skin mast cells and disease activity in chronic inducible urticaria .
    Barzolvolimab
  • HY-152839

    BLU-263

    c-Kit Cancer
    Elenestinib (BLU-263) is a potent and orally active tyrosine kinase inhibitor that has minimal brain penetration. Elenestinib inhibits KIT D816V with an IC50 value of 0.2 nM. MElenestinib has the potential for the research of systemic mastocytosis (SM) .
    Elenestinib
  • HY-160765

    APS-8-100-2

    Wnt Apoptosis Cancer
    WNTinib (APS-8-100-2) is a multi-kinase inhibitor that selectively antagonizes β-catenin (CTNNB1) mutated hepatocellular carcinoma (HCC). WNTinib downregulates oncogenicWntsignaling by inhibiting KIT/MAPK and downstream EZH2 activation .
    WNTinib

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