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Results for "

Jagged-1

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

4

Peptides

2

Natural
Products

4

Recombinant Proteins

2

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P1846A
    Jagged-1 (188-204) (TFA)
    5 Publications Verification

    		 Notch Cancer
    Jagged-1 (188-204) TFA is a fragment of the Jagged-1 (JAG-1) protein with Notch agonist activity. JAG-1 is a Notch ligand highly expressed in cultured and primary multiple myeloma (MM) cells. JAG-1 induces maturation of monocyte-derived human dendritic cells [1] .
    <em>Jagged-1</em> (188-204) (TFA)
  • HY-N0711
    Carvacrol
    2 Publications Verification

    Cymophenol

    		 Notch Apoptosis Fungal Endogenous Metabolite Bacterial Infection Inflammation/Immunology Cancer
    Carvacrol is an orally active monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations [1] .
    Carvacrol
  • HY-P1846
    Jagged-1 (188-204)

    		Notch Cancer
    Jagged-1 (188-204) is a fragment of the Jagged-1 (JAG-1) protein with Notch agonist activity. JAG-1 is a Notch ligand highly expressed in cultured and primary multiple myeloma (MM) cells. JAG-1 induces maturation of monocyte-derived human dendritic cells [1] .
    <em>Jagged-1</em> (188-204)
  • HY-N9790
    Procyanidin B2 3,3'-di-O-gallate

    		Notch Others
    Procyanidin B2, 3,3'-di-O-gallate is an active constituent. Procyanidin B2, 3,3'-di-O-gallate can be isolated from grape seed extract (GSE) procyanidin mix. Procyanidin B2, 3,3' -di-o-gallate target cancer stem cells (CSCs) in prostate cancer (PCa). Procyanidin B2, 3,3'-di-O-gallate targets both unsorted and sorted CSCs at lower doses. Procyanidin B2, 3,3'-di-O-gallate strongly suppresses the constitutive as well as Jagged1 (Notch1 ligand)-induced activated Notch1 pathway [1].
    Procyanidin B2 3,3'-di-O-gallate

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