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Keap1-Nrf2-IN-14

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-151362
    Keap1-Nrf2-IN-14

    		Keap1-Nrf2 Reactive Oxygen Species Inflammation/Immunology
    Keap1-Nrf2-IN-14 (compound 20c) is a KEAP1-NRF2 inhibitor that effectively disrupts the KEAP1-NRF2 interaction (IC50=75 nM) with a Kd value of 24 nM for KEAP1. Keap1-Nrf2-IN-14 induces the expression of NRF2 target genes and enhances the downstream antioxidant and anti-inflammatory activities. Keap1-Nrf2-IN-14 can be used in the study of oxidative stress-related inflammation .
    <em>Keap1-Nrf2-IN-14</em>

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