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Results for "

LC3B

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Atg7 (2) Atg8/LC3 (7) ATTECs (4) AUTACs (2) Autophagy (10) Mitophagy (1) p62 (1) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (6) Infection (1) Inflammation/Immunology (2) Metabolic Disease (2) Neurological Disease (3)

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Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-141882

DC-LC3in-D5	Atg8/LC3 Autophagy	Infection Inflammation/Immunology Cancer
DC-LC3in-D5 acts as an autophagy inhibitor by attenuating LC3B lipidation. DC-LC3in-D5 binds with LC3B. DC-LC3in-D5 disrupts the LC3B-LBP2 interaction with an IC₅₀ of 200 nM. DC-LC3in-D5 may contribute to anti-HCV or combination researchs in cancer through inhibiting autophagy .

HY-146130

ATG7-IN-2

Atg7 Autophagy Cancer

ATG7-IN-2 (compound 1) is a potent ATG7 inhibitor, with an IC₅₀ of 0.089 μM. ATG7-IN-2 inhibits autophagy marker LC3B .

ATG7-IN-2	Atg7 Autophagy	Cancer
ATG7-IN-2 (compound 1) is a potent ATG7 inhibitor, with an IC₅₀ of 0.089 μM. ATG7-IN-2 inhibits autophagy marker LC3B .

HY-157209

LD-ATTEC4	ATTECs Atg8/LC3 Autophagy	Metabolic Disease
LD-ATTEC4 (compound 4A) is a coupling compound that can bind to LC3, with a K_d of 0.39 μM for LC3B. LD-ATTEC4 can connect autophagosomes with lipid droplets, inducing autophagy to clear lipid droplets .

HY-146131

ATG7-IN-3	Atg7 Atg8/LC3 Autophagy	Cancer
ATG7-IN-3 (compound 18) is a potent ATG7 inhibitor, with an IC₅₀ of 0.048 μM. ATG7-IN-3 inhibits autophagy. ATG7-IN-3 inhibits the formation of endogenous LC3B puncta in the neuroglioma cell line H4 .

HY-157304

ATTECs Degrader 1	Atg8/LC3 ATTECs Autophagy Mitophagy	Neurological Disease
ATTECs Degrader 1 (Compound MT1) is an ATTECs compound. ATTECs Degrader 1 can bind to both the outer mitochondrial membrane protein (TSPO) and the autophagosome protein *LC3B*. ATTECs Degrader 1 enhances the degradation of damaged mitochondria by autophagosomes and subsequent autophagic degradation .

HY-112698

CA-5f	p62 Atg8/LC3 Autophagy Apoptosis	Cancer
CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion. CA-5f increases LC3B-II (a marker to monitor autophagy) and SQSTM1 protein, and also increases ROS production. Anti-tumor activity .

HY-130258

LC3-mHTT-IN-AN1	Atg8/LC3 ATTECs Autophagy	Neurological Disease
LC3-mHTT-IN-AN1 (Compound AN1) is a *mHTT-LC3* linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons .

HY-130259

LC3-mHTT-IN-AN2	Atg8/LC3 ATTECs Autophagy	Neurological Disease
LC3-mHTT-IN-AN2 (Compound AN2) is a *mHTT-LC3* linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons .

HY-RS08029

MAP1LC3B Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MAP1LC3B Human Pre-designed siRNA Set A contains three designed siRNAs for MAP1LC3B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MAP1LC3B Human Pre-designed siRNA Set A MAP1LC3B Human Pre-designed siRNA Set A

HY-RS08030

MAP1LC3B2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MAP1LC3B2 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP1LC3B2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MAP1LC3B2 Human Pre-designed siRNA Set A MAP1LC3B2 Human Pre-designed siRNA Set A

HY-134183

AUTAC1	AUTACs Autophagy	Metabolic Disease Cancer
AUTAC1 is a MetAP2-targeting autophagy-mediated degrader (AUTAC). AUTACs contain a degradation tag and a warhead to provide target specificity. AUTAC1 contains an FBnG (p-Fluorobenzyl Guanine) and a Fumagillol moiety. Fumagillol binds covalently to MetAP2 .

HY-134184

AUTAC2	AUTACs Autophagy	Inflammation/Immunology Cancer
AUTAC2 is a FKBP12-targeting autophagy-mediated degrader (AUTAC). AUTAC2 contains an FBnG (p-Fluorobenzyl Guanine) and an SLF (c ligand of FKBP) moiety. SLF binds non-covalently to FKBP12 .

LC3-mHTT-IN-AN2	Structural Classification other families Source classification Coumarins Phenols Polyphenols Phenylpropanoids Plants	Atg8/LC3 ATTECs Autophagy
LC3-mHTT-IN-AN2 (Compound AN2) is a *mHTT-LC3* linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons .

Cat. No.	Compare	Product Name	Species	Source

HY-P70909

	MAP1LC3B Protein, Human Microtubule-associated proteins 1A/1B light chain 3B; Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; MAP1 light chain 3-like protein 2; MAP1A/MAP1B light chain 3 B; MAP1A/MAP1B LC3 B; Microtubule-associated protein 1 light cha	Human	E. coli
	MAP1LC3B is a key ubiquitin-like modifier essential for the formation of autophagosome vacuoles, which maintains cellular homeostasis. In mitophagy, it regulates mitochondrial number, suppresses reactive oxygen species and ensures energy efficiency. MAP1LC3B Protein, Human is the recombinant human-derived MAP1LC3B protein, expressed by E. coli , with tag free. The total length of MAP1LC3B Protein, Human is 125 a.a., with molecular weight of ~16.15 kDa.


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Cat. No.	Product Name	Application	Reactivity

HY-P80741

LC3A/B Antibody LC3; LC3A; ATG8E; MAP1ALC3; MAP1BLC3; MAP1LC3A; LC3B; ATG8F; MAP1LC3B-a; MAP1A/1BLC3; MAP1LC3B	WB	Human, Mouse, Rat
LC3A/B Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 14 kDa, targeting to LC3A/B. It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P80742

LC3B Antibody MAP1LC3B	WB, ICC/IF, IHC-F, IHC-P	Human, Mouse, Rat
LC3B Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 15 kDa, targeting to LC3B. It can be used for WB,ICC/IF,IHC-F,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P80209

LC3B Antibody (YA308)	WB, IP	Human
LC3B Antibody (YA308) is a non-conjugated and Rabbit origined monoclonal antibody about 14/16 kDa, targeting to LC3B. It can be used for WB,IP assays with tag free, in the background of Human.

HY-P81226

LC3 Antibody Autophagy related protein LC3 A; Autophagy related protein LC3 B; Autophagy related ubiquitin like modifier LC3 A; Autophagy related ubiquitin like modifier LC3 B; MAP1 light chain 3 like protein 1; MAP1 light chain 3 like protein 2; MAP1A/1B light chain 3 A; MAP1A/1B light chain 3 B; MAP1A/1BLC3; MAP1A/MAP1B LC3 A; MAP1A/MAP1B LC3 B; MAP1ALC3; MAP1BLC3; MAP1LC3A; MAP1LC3B; Microtubule associated protein 1 light chain 3 alpha; Microtubule associated protein 1 light chain 3 beta; Microtubule associated proteins 1A/1B light chain 3; Microtubule associated proteins 1A/1B light chain 3A; Microtubule associated proteins 1A/1B light chain 3B; MLP3A_HUMAN.	WB; ELISA; IHC-P; IHC-F; Flow-Cyt; IF	Human, Rat(predicted: Mouse, Chicken, Dog, Pig, Cow, Horse, Sheep, Goat)
LC3 Antibody is an unconjugated, approximately 14/16 kDa, rabbit-derived, anti-LC3 polyclonal antibody. LC3 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, rat, and predicted: mouse, chicken, dog, pig, cow, horse, sheep, goat background without labeling.

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