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Results for "

LNP

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (7) CD19 (2) Complement System (2) CRISPR/Cas9 (1) Endogenous Metabolite (1) Fluorescent Dye (2) Isotope-Labeled Compounds (3) Liposome (108) SARS-CoV (2) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (12) Endocrinology (1) Infection (7) Inflammation/Immunology (9) Metabolic Disease (4) Neurological Disease (4)

111

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-153852

LNP Lipid-7

Liposome Others

1LNP Lipid-7 (Compound 7013) is a lipid. LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) and for drug delivery .

LNP Lipid-7	Liposome	Others
1LNP Lipid-7 (Compound 7013) is a lipid. LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) and for drug delivery .

HY-154974

LNP Lipid-8	Liposome	Cancer
LNP Lipid-8 (11-A-M) is an ionizable lipid, which can be used for lipid nanoparticles (LNP) to deliver siRNA to T cells without targeting to ligands. LNP LIPs-8 loaded with GFP siRNA (siGFP), and significantly causes GFP gene silencing in mice model .

HY-153375

LNP Lipid-5

Liposome Others

LNP Lipid-5 (Compound Lipid 2) is an ionizable lipid (amino lipid). LNP Lipid-5 can be used to prepare lipid nanoparticles (LNP) .
HY-153376

LNP Lipid-6

Liposome Others

LNP Lipid-6 (Compound Lipid 5) is an ionizable lipid (amino lipid). LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) .

LNP Lipid-5	Liposome	Others
LNP Lipid-5 (Compound Lipid 2) is an ionizable lipid (amino lipid). LNP Lipid-5 can be used to prepare lipid nanoparticles (LNP) .

LNP Lipid-6	Liposome	Others
LNP Lipid-6 (Compound Lipid 5) is an ionizable lipid (amino lipid). LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) .

HY-153187

LNP Lipid-4	Liposome	Others
LNP Lipid-4 (Compound 8-8) is a lipid compound. LNP Lipid-4 is involved in the synthesis of lipid nanoparticles compositions. LNP Lipid-4 has potential applications in the transportation of biologically active substances .

HY-153186

LNP Lipid-3

Liposome Others

LNP Lipid-3 is an ionizable lipid extracted from patent WO2021113777A, and can be used for the generation of Lipid nanoparticles (LNPs).

LNP Lipid-3	Liposome	Others
LNP Lipid-3 is an ionizable lipid extracted from patent WO2021113777A, and can be used for the generation of Lipid nanoparticles (LNPs).

HY-127105A

Iptacopan hydrochloride 3 Publications Verification LNP023 hydrochloride	Complement System Liposome	Metabolic Disease Inflammation/Immunology
LNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor. LNP023 shows direct, reversible, and high-affinity binding to human factor B with a K_D of 7.9 nM. LNP023 inhibits factor B with an IC₅₀ value of 10 nM .

HY-153136

LNP Lipid-1	Liposome	Others
LNP Lipid-1 (Method B) is a lipid compound. LNP Lipid-1 is involved in the synthesis of lipid nanoparticles compositions. LNP Lipid-1 has potential applications in the transport of biologically active substances such as small molecule agents, proteins, and nucleic acids .

HY-142992

LNP Lipid-2

Biochemical Assay Reagents Liposome Others

LNP Lipid-2 is a lipid product can be used to deliver agents .

LNP Lipid-2	Biochemical Assay Reagents Liposome	Others
LNP Lipid-2 is a lipid product can be used to deliver agents .

HY-RS07729

LNP1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
LNP1 Human Pre-designed siRNA Set A contains three designed siRNAs for LNP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

LNP1 Human Pre-designed siRNA Set A LNP1 Human Pre-designed siRNA Set A

HY-127105

Iptacopan 3 Publications Verification LNP023	Complement System	Metabolic Disease Inflammation/Immunology
Iptacopan (LNP023) is a first-in-class, orally bioavailable, highly potent and highly selective factor B inhibitor with an IC₅₀ value of 10 nM. Iptacopan shows direct, reversible, and high-affinity binding to human factor B with a K_D of 7.9 nM. Iptacopan targets the underlying cause of complement 3 glomerulopathy (C3G) .

HY-153231

eGFP mRNA-LNP	Fluorescent Dye Liposome	Others
eGFP mRNA-LNP is a lipid nanoparticle (LNP) containing eGFP mRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. eGFP circRNA carries Enhanced Green Fluorescent Protein (Enhanced Green Fluorescent Protein) eGFP, which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry .

HY-153232

eGFP circRNA-LNP	Fluorescent Dye Liposome	Others
eGFP circRNA-LNP is a lipid nanoparticle (LNP) containing eGFP circRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. eGFP circRNA carries Enhanced Green Fluorescent Protein (Enhanced Green Fluorescent Protein) eGFP, which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry .

HY-W590531

80-O16B

Biochemical Assay Reagents Liposome Others

80-O16B is an ionizable cationic lipid containing disulfide bonds that can be used to prepare lipid nanoparticles (LNP) .

80-O16B	Biochemical Assay Reagents Liposome	Others
80-O16B is an ionizable cationic lipid containing disulfide bonds that can be used to prepare lipid nanoparticles (LNP) .

HY-153234

CD19 car circRNA-LNP	CD19 Liposome	Inflammation/Immunology Cancer
CD19 car circRNA-LNP is a lipid nanoparticle (LNP) containing CD19 car circRNA, suitable for detection of RNA delivery, translation efficiency, cell viability, etc. CD19 car circRNA can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction .

HY-153233

CD19 car mRNA-LNP	CD19 Liposome	Inflammation/Immunology Cancer
CD19 car mRNA-LNP is a lipid nanoparticle (LNP) containing CD19 car mRNA, suitable for detection of RNA delivery, translation efficiency, cell viability, etc. CD19 car mRNA can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction .

HY-153235

COVID-19 Spike Protein mRNA-LNP	SARS-CoV Liposome	Infection
COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) containing COVID-19 Spike Protein, suitable for detection of RNA delivery, translation efficiency, cell viability, etc. COVID-19 Spike Protein is the novel coronavirus pneumonia spike protein located on the membrane surface. COVID-19 Spike Protein undertakes the functions of virus binding to host cell membrane receptors and membrane fusion, thereby mediating the entry of COVID-19 virus into cells. COVID-19 Spike Protein is an important site of action for host neutralizing antibodies and a key target for vaccine design .

HY-160578

Glucosamine Cholesterol N-Cholesteryl succinyl glucosamine	Liposome	Others
Glucosamine Cholesterol (N-Cholesteryl succinyl glucosamine) is a glucosamine-based lipid conjugate, and can be used in the formation of lipid nanoparticles (LNPs) .

HY-160553

9322-O16B

Liposome Others

9322-O16B, an ionizable cationic lipid, is used for LNP generation .

9322-O16B	Liposome	Others
9322-O16B, an ionizable cationic lipid, is used for LNP generation .

HY-W590680

ssPalmM	Liposome	Others
ssPalmM is a SS-cleavable proton-activated lipid-like materials. ssPalmM can be used to form lipid nanoparticles (LNPs) for nuclear targeting of plasmid DNA .

HY-156630

Ionizable lipid-1

Liposome Others

Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .

Ionizable lipid-1	Liposome	Others
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .

HY-156630A

Ionizable lipid-1 hydrochloride	Liposome	Others
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .

HY-149156

Lipid C24	Liposome	Cancer
Lipid C24 is a cationic ionizable lipid, and can be used in the formation of lipid nanoparticles (LNPs). Lipid C24 can be used for research of delivery of nucleic acids .

HY-153879

C12-TLRa	Liposome	Infection
C12-TLRa is an adjuvant lipidoid. C12-TLRa acts as a structural component of LNP to enhance mRNA delivery. C12-TLRa substitution can increase antigen-specific antibody responses and B cell responses of clinically relevant mRNA-LNP vaccines .

HY-W598178

93-O17O

Liposome Others

93-O17O is a chalcogen-containing ionizable cationic lipidoid that used in the formation of lipid nanoparticles (LNPs) .
HY-143700

18:0 DAP

Liposome Neurological Disease

18:0 DAP can be used to formulate lipid nanoparticles (LNPs), which mRNA is encapsulated in their core .
HY-151507

306Oi10

Liposome Others

306Oi10 is a branched-chain ionizable lipidoid that can be used for constructing lipid nanoparticles (LNPs) for the delivery of messenger RNA .
HY-160439

Ionizable lipid-2

Liposome Others

Ionizable lipid-2 (compound 1) is an ionizable lipid used for nucleic acid delivery and construct lipid nanoparticles (LNPs) .

93-O17O	Liposome	Others
93-O17O is a chalcogen-containing ionizable cationic lipidoid that used in the formation of lipid nanoparticles (LNPs) .

18:0 DAP	Liposome	Neurological Disease
18:0 DAP can be used to formulate lipid nanoparticles (LNPs), which mRNA is encapsulated in their core .

306Oi10	Liposome	Others
306Oi10 is a branched-chain ionizable lipidoid that can be used for constructing lipid nanoparticles (LNPs) for the delivery of messenger RNA .

Ionizable lipid-2	Liposome	Others
Ionizable lipid-2 (compound 1) is an ionizable lipid used for nucleic acid delivery and construct lipid nanoparticles (LNPs) .

HY-148363

Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate	Liposome	Inflammation/Immunology
Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate can be used in lipid nanoparticles (LNP) delivery systems for mRNA vaccine delivery .

HY-139305

CL4H6	Liposome	Cancer
CL4H6 is a pH-sensitive cationic lipid. CL4H6 is the main component of lipid nanoparticles (LNPs), which can be used to target and deliver siRNA, and induces a potent gene-silencing response .

HY-138170

ALC-0315 Maximum Cited Publications 7 Publications Verification	Liposome SARS-CoV	Infection
ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .

HY-112758

DLin-KC2-DMA 4 Publications Verification	Liposome	Others
DLin-KC2-DMA is an ionisable cationic lipid (pKa≈6) that is virtually non-toxic to antigen presenting cells (APCs). DLin-KC2-DMA produces significant siRNA-mediated gene silencing of GAPDH, when binds to lipid nanoparticles (LNP). DLin-KC2-DMA can be used in siRNA delivery studies .

HY-112763

CLinDMA	Liposome	Inflammation/Immunology
CLinDMA, a cationic lipid, can cause inflammatory response. CLinDMA can be used for the synthesis LNP201. LNP201 is a liposome assembly for systemic delivery of siRNA .

HY-160552

244cis	Liposome	Others
244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels .

HY-160579

MIC5

Liposome Others

MIC5 is an LNP that can be used for vaccine delivery .

MIC5	Liposome	Others
MIC5 is an LNP that can be used for vaccine delivery .

HY-147332

TCL053	Liposome	Neurological Disease
TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle .

HY-150116

Lipid 1

Liposome Others

Lipid 1 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
HY-150115

Lipid 10

Liposome Others

Lipid 10 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
HY-153378

Lipid 15

Liposome Others

Lipid 15 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
HY-150117

Lipid 6

Liposome Others

Lipid 6 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
HY-150118

Lipid 8

Liposome Others

Lipid 8 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

Lipid 1	Liposome	Others
Lipid 1 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

Lipid 10	Liposome	Others
Lipid 10 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

Lipid 15	Liposome	Others
Lipid 15 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

Lipid 6	Liposome	Others
Lipid 6 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

Lipid 8	Liposome	Others
Lipid 8 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

HY-134541

SM-102 Maximum Cited Publications 7 Publications Verification	Liposome	Infection
SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-134782

OF-Deg-Lin

Liposome Others

OF-Deg-Lin is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
HY-153377

Lipid 14

Liposome Inflammation/Immunology

Lipid 14 is a potent ionizable lipid and can be used to synthesize lipid nanoparticles (LNPs) .
HY-153373

4A3-Cit

Liposome Others

4A3-Cit is an ionizable lipid used for the generation of lipid nanoparticles (LNPs).
HY-W590532

306-O12B

Liposome Others

306-O12B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs).

OF-Deg-Lin	Liposome	Others
OF-Deg-Lin is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

Lipid 14	Liposome	Inflammation/Immunology
Lipid 14 is a potent ionizable lipid and can be used to synthesize lipid nanoparticles (LNPs) .

4A3-Cit	Liposome	Others
4A3-Cit is an ionizable lipid used for the generation of lipid nanoparticles (LNPs).

306-O12B	Liposome	Others
306-O12B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs).

HY-W800783

DSTAP chloride CDESA	Liposome	Others
DSTAP chloride (CDESA) is a cationic lipid that used in the formation of lipid nanoparticles (LNPs). DORI chloride has high transfection efficiency .

HY-160576

DNCA

Liposome Cancer

DNCA is a neutral lipid that can be used in the generation of lipid nanoparticles (LNPs). DNCA can be used in nucleic acid delivery .
HY-153372

93-O17S

Liposome Others

93-O17S is a chalcogen-containing ionizable cationic lipid used for making lipid nanoparticles (LNPs).

HY-137500

NT1-014B	Liposome	Neurological Disease
NT1-014B is a potent NT1-lipidoid encapsulated AmB (amphotericin B). NT1-014B dopes the NT-lipidoids into BBB-impermeable lipid nanoparticles (LNPs) gave the LNPs the ability to cross the BBB. NT1-014B enhances brain delivery through intravenous injection .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-137499

NT1-O12B	Structural Classification Alkaloids Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Indole Alkaloids	Liposome Endogenous Metabolite
NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .

Cat. No.	Product Name	Chemical Structure

HY-W040193S

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70
1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₇₀ is the deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2].

HY-W040193S3

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d83
1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₈₃ is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2].

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