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LTG

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Autophagy (7) Isotope-Labeled Compounds (1) Sodium Channel (7)
By Research Areas:	Cancer (1) Neurological Disease (6)

7

Inhibitors & Agonists

2

Recombinant Proteins

4

Isotope-Labeled Compounds

1

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Lamotrigine Maximum Cited Publications 6 Publications Verification LTG; BW430C	Sodium Channel Autophagy	Neurological Disease
Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na ⁺ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al .

Lamotrigine-d3 LTG-d₃; BW430C-d₃	Autophagy Sodium Channel
Lamotrigine-d3 is the deuterium labeled Lamotrigine[1]. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[2][3].

Lamotrigine hydrate LTG hydrate; BW430C hydrate	Sodium Channel Autophagy	Neurological Disease
Lamotrigine hydrate is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine hydrate selectively blocks voltage-gated Na ⁺ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine hydrate can be used for the research of epilepsy, focal seizure, et al .

Lamotrigine isethionate LTG isethionate; BW430C isethionate	Sodium Channel Autophagy	Neurological Disease Cancer
Lamotrigine (BW430C) isethionate is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine isethionate selectively blocks voltage-gated Na ⁺ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine isethionate can be used for the research of epilepsy, focal seizure, et al .

Lamotrigine-13C3 LTG-¹³C₃; BW430C-¹³C₃	Sodium Channel Autophagy	Neurological Disease
Lamotrigine- ¹³C₃ is the ¹³C-labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[1][2].

Lamotrigine-13C,d3 LTG-¹³C,d₃; BW430C-¹³C,d₃	Isotope-Labeled Compounds Sodium Channel Autophagy	Neurological Disease
Lamotrigine- ¹³C,d₃ is the ¹³C- and deuterium labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[1][2].

Lamotrigine-13C3,d3 LTG-¹³C₃,d₃; BW430C-¹³C₃,d₃	Sodium Channel Autophagy	Neurological Disease
Lamotrigine- ¹³C₃,d₃ is the ¹³C-labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[1][2].

Species:	Human (2)
Tag:	His (2) Flag (1)
Source:	HEK293 (2)

Cat. No.	Compare	Product Name	Species	Source

	LIGHT/TNFSF14 Protein, Human (HEK293, His) Tumor necrosis factor ligand superfamily member 14; TNFSF14; HVEM-L; LIGHT	Human	HEK293
	LIGHT/TNFSF14 protein (CD258; TNFRSF14) is a type II transmembrane protein produced by activated T cells. It is a TNFRSF14/HVEM ligand and belongs to the tumor necrosis factor (TNF) family. LIGHT/TNFSF14 is mainly expressed in spleen, with two subtypes: membrane-bound type and soluble type . LIGHT/TNFSF14 protein can be used as immune checkpoint molecule of tumor, and stimulate natural killer cells to produce interferon TFNγ, triggering tumor apoptosis signal . LIGHT/TNFSF14 is also involved in the dominant LTβR-NIK-p52 NF-κB pathway promoting the expression of inflammatory gene. In addition, LIGHT/TNFSF14 protein is a co-stimulatory factor that activates lymphoid cells and has an inhibitory effect on herpes virus infection. LIGHT/TNFSF14 Protein, Human (HEK293, His) is produced by HEK293 cells (L83-V240), with N-terminal 6*His-tag.

	LIGHT/TNFSF14 Trimer Protein, Human (HEK293, His-Flag) CD258; TNFSF14; HVEM-L; LIGHT; LTG; TR2	Human	HEK293
	LIGHT/TNFSF14 protein (CD258; TNFRSF14) is a type II transmembrane protein produced by activated T cells. It is a TNFRSF14/HVEM ligand and belongs to the tumor necrosis factor (TNF) family. LIGHT/TNFSF14 is mainly expressed in spleen, with two subtypes: membrane-bound type and soluble type . LIGHT/TNFSF14 protein can be used as immune checkpoint molecule of tumor, and stimulate natural killer cells to produce interferon TFNγ, triggering tumor apoptosis signal . LIGHT/TNFSF14 is also involved in the dominant LTβR-NIK-p52 NF-κB pathway promoting the expression of inflammatory gene. In addition, LIGHT/TNFSF14 protein is a co-stimulatory factor that activates lymphoid cells and has an inhibitory effect on herpes virus infection. Human LIGHT/TNFSF14 Protein has 240 amino acids and a transmembrane domain (38-58 a.a.). LIGHT/TNFSF14 Trimer Protein, Human (HEK293, His-Flag) is the extracellular part (S89-V240) of human LIGHT/TNFSF14 Protein, produced by HEK293 cells, with N-terminal His- and Flag-tag.

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