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Lesinurad

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15258
    Lesinurad
    1 Publications Verification

    RDEA594

    		 URAT1 Metabolic Disease
    Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 µM, respectively.
    <em>Lesinurad</em>
  • HY-15258A
    Lesinurad sodium
    1 Publications Verification

    RDEA-594 sodium

    		 URAT1 Metabolic Disease
    Lesinurad sodium is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 µM, respectively.
    <em>Lesinurad</em> sodium
  • HY-153969
    URAT1 inhibitor 6

    		URAT1 Inflammation/Immunology
    URAT1 inhibitor 6 (Compound 1h) is a potent URAT1 inhibitor (IC50: 35 nM for hURAT1). URAT1 inhibitor 6 is 200- and 8-fold more potent than parent Lesinurad (HY-15258) and Benzbromarone (HY-B1135). URAT1 inhibitor 6 can be used for research of inflammation .
    URAT1 inhibitor 6
  • HY-152033
    URAT1 inhibitor 4

    		URAT1 GLUT Metabolic Disease
    URAT1 inhibitor 4, a Lesinurad derivative, is a potent and orally active URAT1 inhibitor with an IC50 of 7.56 μM. URAT1 inhibitor 4 has higher in vivo urate-lowering efficacy than Lesinurad (HY-15258) .
    URAT1 inhibitor 4

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