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Isoforms Recommended: MAP3K8
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MAP3K8

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Compare Product Name Species Source
  • HY-P75921
    MAP3K8/TPL-2 Protein, Human (sf9, GST)

    Mitogen-activated protein kinase kinase kinase 8; TPL-2; MAP3K8; COT; ESTF

    		 Human Sf9 insect cells
    MAP3K8/TPL-2 is critical for LPS-induced, TLR4-mediated activation of MAPK/ERK, leading to TNF production by macrophages. It regulates T cell differentiation, IFNG expression, and host resistance to bacterial infections by negatively regulating type I interferon production. MAP3K8/TPL-2 Protein, Human (sf9, GST) is the recombinant human-derived MAP3K8/TPL-2 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of MAP3K8/TPL-2 Protein, Human (sf9, GST) is 368 a.a., with molecular weight of ~68 kDa.

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