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MAPT

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  • HY-P71752
    Microtubule-associated protein tau Protein, Mouse (P.pastoris, His)

    MAPT; Mtapt; Tau; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau

    		 Mouse P. pastoris
    Microtubule-associated protein tau (MAPT) plays a key role in promoting microtubule assembly and stability, suggesting its potential contribution to the establishment of neuronal polarity. The C terminus binds to axonal microtubules, whereas the N terminus interacts with neuroplasmic membrane components, serving as a key linker protein between these structures. Microtubule-associated protein tau Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Microtubule-associated protein tau protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of Microtubule-associated protein tau Protein, Mouse (P.pastoris, His) is 732 a.a., with molecular weight of ~78.1 kDa.
  • HY-P700422
    Tau/MAPT Protein, Mouse (HEK293, His)

    MAPT; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; microtubule-associated protein tau; microtubule-associated protein tau; PHF-tau; paired helical filament-tau; neurofibrillary tangle protein; microtubule-associated protein tau, isoform 4; G protein beta1/gamma2 subunit-interacting factor 1

    		 Mouse HEK293
    Microtubule-associated protein tau (MAPT) plays a pivotal role in promoting microtubule assembly and stability, indicating its potential contribution to neuronal polarity establishment. The C-terminus binds to axonal microtubules, while the N-terminus interacts with neural plasma membrane components, serving as a crucial linker protein between these structures. Tau's localization within the neuronal cell, particularly in the centrosome-defined domain, dictates axonal polarity. Short MAPT isoforms enhance cytoskeletal plasticity, while longer isoforms stabilize it. MAPT engages in diverse interactions with proteins like MARK1, MARK2, MARK3, MARK4, SQSTM1, PSMC2, FKBP4, CSNK1D, SGK1, EPM2A, PIN1, LRRK2, and LRP1, participating in processes from ubiquitination to dephosphorylation and endocytosis, underscoring its multifaceted role in cellular dynamics. Tau/MAPT Protein, Mouse (HEK293, His) is the recombinant mouse-derived Tau/MAPT protein, expressed by HEK293, with N-10*His labeled tag. The total length of Tau/MAPT Protein, Mouse (HEK293, His) is 732 a.a., with molecular weight of 78.9 kDa.

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