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Results for "

MEST Inhibitors

" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-14336A
    SB 271046 Hydrochloride

    SB 271046A

    5-HT Receptor Neurological Disease
    SB 271046 Hydrochloride (SB 271046A) is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 9.02, 8.55, and 8.81 for rat, pig and human, respectively. SB 271046 Hydrochloride is over 200 fold selective for the 5-HT6 receptor vs 55 other receptors, binding sites and ion channels. Anticonvulsant activity (EC50=0.16 μM).