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Ac-YR-NH2 is a small molecule modulator of MHC class II antigen presentation. Ac-YR-NH2 can influence peptide binding by MHC II to influence immune response .
J10-1 is a hapten. J10-1 promotes peptide exchange of all DR alleles (DR1, DR2, DR4 (DRB1*0401)) and promotes peptide binding to MHC II, which can be used in the study of immune regulation .
Favezelimab (MK-4280) is a humanized anti-LAG-3 monoclonal antibody that blocks the interaction between LAG-3 and its ligand MHC class II. Favezelimab has the potential for colorectal cancer (CRC) research combined with the PD-L1 inhibitor Pembrolizumab (HY-P9902) .
AdCaPy is an MHC II antigen loading catalyst that accelerates the loading of peptide antigens by MHC II. AdCaPy is a useful molecular tool for enhancing immune responses .
Relatlimab (BMS-986016) is a human monoclonal antibody anti-LAG-3 antibody generated by immunization of transgenic mice bearing human immunoglobulin miniloci with recombinant LAG-3 protein. Relatlimab blocks LAG-3/MHC II interaction with an IC50 value of 0.67 nM and LAG-3/FGL1 interaction with an IC50 value of 0.019 nM. Relatlimab can be used in research of cancer .
Ieramilimab (LAG525; IMP701) is a humanized IgG4 monoclonal antibody that binds to LAG-3, resulting in inhibition of LAG-3 interaction with MHC-II molecules .
Miptenalimab (BI-754111) is an anti-human LAG-3 antibody (KD: 88.6 nM for h LAG-3). Miptenalimab blocks the interaction of LAG-3 with its ligand MHC-II .
Sulfamethoxazole-NO (SMX-NO) hydrate is the reactive metabolite of SMX (HY-B0322). Sulfamethoxazole-NO (SMX-NO) hydrate actis as a typical hapten and is capable of covalently modifying the MHC-peptide complex, can stimulate hapten-reactive T cells .
LLO (91-99) (Listeriolysin O (91-99)), an exotoxin, is a class I MHC-restricted T-cell epitopes of listeriolysin (LLO). LLO (91-99) is an essential antigen for induction of T-cell mediated immunity in vivo .
LCMV gp33-41, the carboxyl-extended 11-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes .
Zharp1-211 is a potent inhibitor of RIPK1 kinase. Zharp1-211 significantly reduces the expression of JAK/STAT1-mediated chemokines and MHC class II molecules in intestinal epithelial cells .
LCMV gp33-41 (TFA), the carboxyl-extended 11-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes .
Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil . Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat .
Eftilagimod alfa (IMP321) is a recombinant LAG-3Ig fusion protein that binds to MHC class II. Eftilagimod alfa mediates antigen-presenting cell (APC) activation followed by CD8 T-cell activation. Eftilagimod alfa can be used for metastatic melanoma and metastatic breast carcinoma research .
Pristane-d40 is the deuterium labeled Pristane[1]. Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil[2]. Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat[3].
Glatiramer acetate, a synthetic analogue of myelin basic protein and an immunomodulating agent, can be used for the research of multiple sclerosis. Glatiramer acetate exhibits strong and promiscuous binding to MHC molecules and consequent competition with various myelin antigens for their presentation to T cells. A further aspect of its action is potent induction of specific suppressor cells of the T helper 2 (Th2) type that migrate to the brain and lead to in situ bystander suppression .
Cardiogenol C hydrochloride is a potent cell-permeable pyrimidine inducer which prompts the differentiation of ESCs into cardiomyocytes (EC50=100 nM) . Cardiogenol C hydrochloride also acts cardiomyogenic on already lineage-committed progenitor cell types with a limited degree of plasticity. Cardiogenol C hydrochloride is a useful cardiomyogenic agent and can be used as a tool to improve cardiac repair by cell transplantation therapy in animal models .
Cardiogenol C is a potent cell-permeable pyrimidine inducer which prompts the differentiation of ESCs into cardiomyocytes (EC50=100 nM) . Cardiogenol C also acts cardiomyogenic on already lineage-committed progenitor cell types with a limited degree of plasticity. Cardiogenol C is a useful cardiomyogenic agent and can be used as a tool to improve cardiac repair by cell transplantation therapy in animal models .
Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect .
Tebotelimab (MGD-013) is a humanized IgG4κ bispecific PD-1/LAG-3 dual-affinity re-targeting (DART) antibody. Tebotelimab binds cell-surface expressed PD-1 and LAG-3 with EC50s of 1.65 nM and 0.41 nM in NS0 cells, respectively. Tebotelimab blocks PD-1/PD-L1, PD-1/PD-L2 and LAG-3/HLA (MHC-II) interactions and PD-1 signaling. Tebotelimab restores exhausted T-cell responses and and enhances antitumour immunity .
Tyrosinase-related Protein 2 (TRP-2) (181-188) is a tyrosinase-related protein 2 (TRP-2)-derived peptide, corresponding to residues 180-188. Tyrosinase-related Protein 2 (TRP-2) (181-188) is the major reactive epitope within TRP-2 recognized by anti-B16 CTLs. Tyrosinase-related Protein 2 (TRP-2) (181-188) is a peptide conforming to the MHC class I H2-Kb binding motif .
OVA peptide mainly exists in egg white, it is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC). OVA peptide has been widely studied in allergy research .
OVA-Q4 Peptide is a biological active peptide. (Q4 Peptide (SIIQFEKL) is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC).)
OVA-T4 Peptide (SIITFEKL, OVA (257-264) Variant) is a biological active peptide. (T4 peptide (SIITFEKL) is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC).)
LLO (190-201) (Listeriolysin O 190 peptide) is a biological active peptide. (This peptide is a major histocompatibility complex class II (MHC-II)-restricted peptide, LLO190 (NEKYAQAYPNVS), from the listeriolysin O protein of Listeria monocytogenes, which generates an LLO190-specific Th response. This peptide subsequently challenge recombinant L. monocytogenes expressing the MHC-I-restricted epitope of ovalbumin (Ova257, SIINFEKL).)
OVA Peptide(257-264) is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide can be from ovalbumin presented by the class I MHC molecule, H-2Kb.
OVA Peptide(257-264) TFA is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide can be from ovalbumin presented by the class I MHC molecule, H-2Kb.
LLO (91-99) (Listeriolysin O (91-99)), an exotoxin, is a class I MHC-restricted T-cell epitopes of listeriolysin (LLO). LLO (91-99) is an essential antigen for induction of T-cell mediated immunity in vivo .
OVA Peptide(257-264) acetate salt is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide can be from ovalbumin presented by the class I MHC molecule, H-2Kb .
LCMV gp33-41, the carboxyl-extended 11-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes .
LCMV gp33-41 (TFA), the carboxyl-extended 11-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes .
VLHDDLLEA is a peptide that can be isolated from the MHC complex HLA-A*0201 molecule. VLHDDLLEA can be recognized by HLA-A*0201-restricted cytotoxic T cells (CTLs). VLHDDLLEA can be used for research on graft versus host disease (GvHD) .
InsB (9-23) is an insulin B-chain peptide that binds to a class II histocompatibility complex (MHC) allele called I-Ag7. InsB (9-23) can be used to treat a number of autoimmune related diseases like Type 1 diabetes .
CFP10 (71–85) is a biological active peptide. (CFP1071–85, that elicited IFN-γ production and CTL activity by both CD4+ and CD8+ T cells from persons expressing multiple MHC class II and class I molecules)
GAD65 (206-220) is glutamic acid decarboxylase (GAD) 65-derived peptide, corresponding to residues 180-188. GAD65 is presented to T cells in association with I-Ag7 MHC class II molecules and a major pancreatic antigens targeted by self-reactive T cells in type I diabetes mellitus .
CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site .
CLIP (86-100) TFA is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site .
NY-ESO-1 (87-111) is a pan-MHC class II-restricted peptide sequence. NY-ESO-1 (87-111) binds to multiple HLA-DR and HLA-DP4 molecules, and stimulates Th1-type and Th-2/Th0-type CD4 + T cells when presented in the context of HLA-DR and HLA-DP4 molecules .
Influenza NP (311-325) is a biological active peptide. (This peptide is amino acids 311 to 325 fragment of the influenza virus nucleoprotein (NP). This bona fide MHC class II restricted epitope from influenza virus was used to study the host immunoresponse during the infection. This peptide elicits the strongest gamma interferon (IFN-gamma) production in the intracellular cytokine assays. It does not stimulate CD8 T-cells in mice.Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)
Anti-Mouse MHC Class II (I-Ak, I-Ar, I-Af, I-As,I-Ag7) Antibody (10-3.6.2) is a mouse-derived IgG2c, κ type antibody inhibitor, targeting to mouse MHC Class II.
Encelimab is an anti-LAG3 antibody. Encelimab blocks the interaction between LAG-3 and MHC II, and enhances T-cell activation. Encelimab alone or in combination with an anti-PD-1 antibody reduces tumor size in a lymphoma mice model (A20 cell xenograft) .
Favezelimab (MK-4280) is a humanized anti-LAG-3 monoclonal antibody that blocks the interaction between LAG-3 and its ligand MHC class II. Favezelimab has the potential for colorectal cancer (CRC) research combined with the PD-L1 inhibitor Pembrolizumab (HY-P9902) .
Polzastobart (JTX-8064) is a humanized IgG4 monoclonal antagonist antibody that selectively binds LILRB2 and prevents it from binding its ligands, classical and non-classical MHC I molecules. Polzastobart enhances pro-inflammatory cytokine production in macrophages by blocking the ability of LILRB2 to bind HLA-A/B and/or HLA-G, a marker of immunotolerance on cancer cells. Polzastobart is a macrophage immune checkpoint inhibitor .
Relatlimab (BMS-986016) is a human monoclonal antibody anti-LAG-3 antibody generated by immunization of transgenic mice bearing human immunoglobulin miniloci with recombinant LAG-3 protein. Relatlimab blocks LAG-3/MHC II interaction with an IC50 value of 0.67 nM and LAG-3/FGL1 interaction with an IC50 value of 0.019 nM. Relatlimab can be used in research of cancer .
Ieramilimab (LAG525; IMP701) is a humanized IgG4 monoclonal antibody that binds to LAG-3, resulting in inhibition of LAG-3 interaction with MHC-II molecules .
Miptenalimab (BI-754111) is an anti-human LAG-3 antibody (KD: 88.6 nM for h LAG-3). Miptenalimab blocks the interaction of LAG-3 with its ligand MHC-II .
Eftilagimod alfa (IMP321) is a recombinant LAG-3Ig fusion protein that binds to MHC class II. Eftilagimod alfa mediates antigen-presenting cell (APC) activation followed by CD8 T-cell activation. Eftilagimod alfa can be used for metastatic melanoma and metastatic breast carcinoma research .
Tebotelimab (MGD-013) is a humanized IgG4κ bispecific PD-1/LAG-3 dual-affinity re-targeting (DART) antibody. Tebotelimab binds cell-surface expressed PD-1 and LAG-3 with EC50s of 1.65 nM and 0.41 nM in NS0 cells, respectively. Tebotelimab blocks PD-1/PD-L1, PD-1/PD-L2 and LAG-3/HLA (MHC-II) interactions and PD-1 signaling. Tebotelimab restores exhausted T-cell responses and and enhances antitumour immunity .
Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil . Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat .
Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect .
HLA-A*1101as is a key MHCI molecule that presents viral and tumor-derived peptides that direct T cell immune responses against infected or transformed cells. It collaborates with B2M to showcase a diverse peptide library. FITC labeled HLA-A*1101 KRAS WT Complex Protein, Human (VVVGAGGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGAGGVGK peptide. FITC labeled HLA-A*1101 KRAS WT Complex Protein, Human (VVVGAGGVGK, HEK293, His-Avi), has molecular weight of 55-60 kDa.
The HLA-C*0304 KRAS G12D Complex, a major histocompatibility complex class I (MHCI) molecule, plays crucial roles in reproduction and antiviral immunity. Teaming up with B2M, it presents self and viral peptides, acting as a dominant ligand for inhibitory and activating killer immunoglobulin receptors (KIRs) on NK cells. In allogeneic contexts, it facilitates trophoblast interactions with NK cells, crucial for placental development. During viral infections, HLA-C*0304 may disrupt KIR-mediated inhibition and promote infected cell lysis. In adaptive immunity, it presents viral peptides to CD8-positive T cells, contributing to antigen-specific T cell responses in chronic viral infections. HLA-C*0304's fine specificity for antigen recognition and its role in immune surveillance stem from its ability to recognize diverse peptides and specific MHC residues. HLA-C*0304 KRAS G12D Complex Tetramer Protein, Human (GADGVGKSAL, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-C*0304 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and GADGVGKSAL peptide. HLA-C*0304 KRAS G12D Complex Tetramer Protein, Human (GADGVGKSAL, HEK293, His-Avi), has molecular weight of 260-265 kDa.
The HLA-C*0304 KRAS G12D Complex, a major histocompatibility complex class I (MHCI) molecule, plays crucial roles in reproduction and antiviral immunity. Teaming up with B2M, it presents self and viral peptides, acting as a dominant ligand for inhibitory and activating killer immunoglobulin receptors (KIRs) on NK cells. In allogeneic contexts, it facilitates trophoblast interactions with NK cells, crucial for placental development. During viral infections, HLA-C*0304 may disrupt KIR-mediated inhibition and promote infected cell lysis. In adaptive immunity, it presents viral peptides to CD8-positive T cells, contributing to antigen-specific T cell responses in chronic viral infections. HLA-C*0304's fine specificity for antigen recognition and its role in immune surveillance stem from its ability to recognize diverse peptides and specific MHC residues. HLA-C*0304 KRAS G12D Complex Protein, Human (GADGVGKSAL, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-C*0304 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and GADGVGKSAL peptide. HLA-C*0304 KRAS G12D Complex Protein, Human (GADGVGKSAL, HEK293, His-Avi), has molecular weight of 55-65 kDa.
The HLA-C*0304 KRAS G12D Complex, a major histocompatibility complex class I (MHCI) molecule, plays crucial roles in reproduction and antiviral immunity. Teaming up with B2M, it presents self and viral peptides, acting as a dominant ligand for inhibitory and activating killer immunoglobulin receptors (KIRs) on NK cells. In allogeneic contexts, it facilitates trophoblast interactions with NK cells, crucial for placental development. During viral infections, HLA-C*0304 may disrupt KIR-mediated inhibition and promote infected cell lysis. In adaptive immunity, it presents viral peptides to CD8-positive T cells, contributing to antigen-specific T cell responses in chronic viral infections. HLA-C*0304's fine specificity for antigen recognition and its role in immune surveillance stem from its ability to recognize diverse peptides and specific MHC residues. HLA-C*0304 KRAS G12D Complex Protein, Human (Biotinylated, GADGVGKSAL, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-C*0304 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and GADGVGKSAL peptide. HLA-C*0304 KRAS G12D Complex Protein, Human (Biotinylated, GADGVGKSAL, HEK293, His-Avi), has molecular weight of 55-65 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*0301 KRAS G12V Complex Protein, Human (VVGAVGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVGAVGVGK peptide. HLA-A*0301 KRAS G12V Complex Protein, Human (VVGAVGVGK, HEK293, His-Avi), has molecular weight of 56-65 kDa.
HLA-A*0301 collaborates with B2M to present viral and tumor peptides, guiding CD8-positive T cell responses against infected or transformed cells. It can also present self-peptides, avoiding autoreactivity. The antigen recognition specificity involves the peptide and MHC residues, with HLA-A*0301 presenting 8 to 13 amino acid peptides, characterized by allele-specific binding motifs. Specific alleles, like A*01:01 and A*03:01, present a distinct repertoire of peptides, including viral and tumor epitopes. HLA-A*0301 KRAS G12V Complex Protein, Human (Biotinylated, VVGAVGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*0301 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVGAVGVGK peptide. HLA-A*0301 KRAS G12V Complex Protein, Human (Biotinylated, VVGAVGVGK, HEK293, His-Avi), has molecular weight of 52-60 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 KRAS G12S Complex Protein, Human (VVVGASGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGASGVGK peptide. HLA-A*1101 KRAS G12S Complex Protein, Human (VVVGASGVGK, HEK293, His-Avi), has molecular weight of 53-63 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 KRAS G12S Complex Protein, Human (Biotinylated, VVVGASGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGASGVGK peptide. HLA-A*1101 KRAS G12S Complex Protein, Human (Biotinylated, VVVGASGVGK, HEK293, His-Avi), has molecular weight of 53-63 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 KRAS G12R Complex Protein, Human (VVVGAAGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGARGVGK peptide. HLA-A*1101 KRAS G12R Complex Protein, Human (VVVGAAGVGK, HEK293, His-Avi), has molecular weight of 53-63 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 KRAS G12R Complex Protein, Human (Biotinylated, VVVGARGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGARGVGK peptide. HLA-A*1101 KRAS G12R Complex Protein, Human (Biotinylated, VVVGARGVGK, HEK293, His-Avi), has molecular weight of 53-63 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 KRAS G12C Complex Protein, Human (VVVGACGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGACGVGK peptide. HLA-A*1101 KRAS G12C Complex Protein, Human (VVVGACGVGK, HEK293, His-Avi), has molecular weight of 53-63 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 KRAS G12C Complex Protein, Human (Biotinylated, VVVGACGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGACGVGK peptide. HLA-A*1101 KRAS G12C Complex Protein, Human (Biotinylated, VVVGACGVGK, HEK293, His-Avi), has molecular weight of 53-63 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 KRAS G12A Complex Protein, Human (VVVGAAGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGAAGVGK peptide. HLA-A*1101 KRAS G12A Complex Protein, Human (VVVGAAGVGK, HEK293, His-Avi), has molecular weight of 52-62 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 KRAS G12A Complex Protein, Human (Biotinylated, VVVGAAGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGAAGVGK peptide. HLA-A*1101 KRAS G12A Complex Protein, Human (Biotinylated, VVVGAAGVGK, HEK293, His-Avi), has molecular weight of 52-62 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 KRAS G12V Complex Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVGAVGVGK peptide. HLA-A*1101 KRAS G12V Complex Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 KRAS G12V Complex Protein, Human (Biotinylated, VVGAVGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVGAVGVGK peptide. HLA-A*1101 KRAS G12V Complex Protein, Human (Biotinylated, VVGAVGVGK, HEK293, His-Avi), has molecular weight of 51-60 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 KRAS G12D Complex Protein, Human (Biotinylated, VVVGADGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGADGVGK peptide. HLA-A*1101 KRAS G12D Complex Protein, Human (Biotinylated, VVVGADGVGK, HEK293, His-Avi), has molecular weight of 51-60 kDa.
HLA-A*0301 collaborates with B2M to present viral and tumor peptides, guiding CD8-positive T cell responses against infected or transformed cells. It can also present self-peptides, avoiding autoreactivity. The antigen recognition specificity involves the peptide and MHC residues, with HLA-A*0301 presenting 8 to 13 amino acid peptides, characterized by allele-specific binding motifs. Specific alleles, like A*01:01 and A*03:01, present a distinct repertoire of peptides, including viral and tumor epitopes. HLA-A*0301 KRAS G12V Complex Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*0301 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVGAVGVGK peptide. HLA-A*0301 KRAS G12V Complex Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-A*0301 collaborates with B2M to present viral and tumor peptides, guiding CD8-positive T cell responses against infected or transformed cells. It can also present self-peptides, avoiding autoreactivity. The antigen recognition specificity involves the peptide and MHC residues, with HLA-A*0301 presenting 8 to 13 amino acid peptides, characterized by allele-specific binding motifs. Specific alleles, like A*01:01 and A*03:01, present a distinct repertoire of peptides, including viral and tumor epitopes. HLA-A*0301 KRAS WT Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*0301 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-His, C-Avi labeled tag and VVVGAGGVGK peptide. HLA-A*0301 KRAS WT Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 KRAS WT Complex Tetramer Protein, Human (VVVGAGGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGAGGVGK peptide. HLA-A*1101 KRAS WT Complex Tetramer Protein, Human (VVVGAGGVGK, HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 KRAS WT Complex Protein, Human (VVVGAGGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGAGGVGK peptide. HLA-A*1101 KRAS WT Complex Protein, Human (VVVGAGGVGK, HEK293, His-Avi), has molecular weight of 52-62 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 KRAS WT Complex Protein, Human (Biotinylated, VVVGAGGVGK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGAGGVGK peptide. HLA-A*1101 KRAS WT Complex Protein, Human (Biotinylated, VVVGAGGVGK, HEK293, His-Avi), has molecular weight of 53-63 kDa.
HLA-A*0301 collaborates with B2M to present viral and tumor peptides, guiding CD8-positive T cell responses against infected or transformed cells. It can also present self-peptides, avoiding autoreactivity. The antigen recognition specificity involves the peptide and MHC residues, with HLA-A*0301 presenting 8 to 13 amino acid peptides, characterized by allele-specific binding motifs. Specific alleles, like A*01:01 and A*03:01, present a distinct repertoire of peptides, including viral and tumor epitopes. HLA-A*0301 KRAS WT Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*0301 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGAGGVGK peptide. HLA-A*0301 KRAS WT Protein, Human (HEK293, His-Avi), has molecular weight of 52-62 kDa.
HLA-A*0301 collaborates with B2M to present viral and tumor peptides, guiding CD8-positive T cell responses against infected or transformed cells. It can also present self-peptides, avoiding autoreactivity. The antigen recognition specificity involves the peptide and MHC residues, with HLA-A*0301 presenting 8 to 13 amino acid peptides, characterized by allele-specific binding motifs. Specific alleles, like A*01:01 and A*03:01, present a distinct repertoire of peptides, including viral and tumor epitopes. HLA-A*0301 KRAS WT Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*0301 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGAGGVGK peptide. HLA-A*0301 KRAS WT Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 52-62 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 KRAS G12V Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVGAVGVGK peptide. HLA-A*1101 KRAS G12V Complex Protein, Human (HEK293, His-Avi), has molecular weight of 42-46 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 KRAS G12D Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGADGVGK peptide. HLA-A*1101 KRAS G12D Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 KRAS G12D Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVVGADGVGK peptide. HLA-A*1101 KRAS G12D Protein, Human (HEK293, His-Avi), has molecular weight of 51-60 kDa.
HLA-A*0301 collaborates with B2M to present viral and tumor peptides, guiding CD8-positive T cell responses against infected or transformed cells. It can also present self-peptides, avoiding autoreactivity. The antigen recognition specificity involves the peptide and MHC residues, with HLA-A*0301 presenting 8 to 13 amino acid peptides, characterized by allele-specific binding motifs. Specific alleles, like A*01:01 and A*03:01, present a distinct repertoire of peptides, including viral and tumor epitopes. HLA-A*0301 KRAS G12V Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*0301 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VVGAVGVGK peptide. HLA-A*0301 KRAS G12V Complex Protein, Human (HEK293, His-Avi), has molecular weight of 55-60 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 NY-ESO-1 Complex Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 NY-ESO-1 Complex Tetramer protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 NY-ESO-1 Complex Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 NY-ESO-1 Complex Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 NY-ESO-1 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 NY-ESO-1 Complex Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 51-60 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 NY-ESO-1 complex Tetramer Protein, Human (SLLMWITQV, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 NY-ESO-1 complex Tetramer protein, expressed by HEK293, with C-Avi, C-His labeled tag. HLA-A*0201 NY-ESO-1 complex Tetramer Protein, Human (SLLMWITQV, HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 NY-ESO-1 Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 NY-ESO-1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 NY-ESO-1 Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 51-56 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 NY-ESO-1 complex Protein, Human (SLLMWITQV, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 NY-ESO-1 complex protein, expressed by HEK293, with C-Avi, C-His labeled tag. HLA-A*0201 NY-ESO-1 complex Protein, Human (SLLMWITQV, HEK293, His-Avi), has molecular weight of 55-60 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 P53 R175H Complex Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 P53 R175H Complex Tetramer protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 P53 R175H Complex Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 P53 R175H Complex Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 P53 R175H Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 P53 R175H Complex Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 51-60 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 LMP2 Complex Tetramer Protein, Human (SSCSSCPLTK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and SSCSSCPLTK peptide. HLA-A*1101 LMP2 Complex Tetramer Protein, Human (SSCSSCPLTK, HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 LMP2 Complex Protein, Human (Biotinylated, SSCSSCPLTK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and SSCSSCPLTK peptide. HLA-A*1101 LMP2 Complex Protein, Human (Biotinylated, SSCSSCPLTK, HEK293, His-Avi), has molecular weight of 51-60 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. Chimeric HLA-A*0201 LMP2 Tetramer Protein, Human&Mouse (HEK293, His-Avi) is the recombinant mouse-derived Chimeric HLA-A*0201 LMP2 Tetramer protein, expressed by HEK293 , with C-Avi, C-His labeled tag. Chimeric HLA-A*0201 LMP2 Tetramer Protein, Human&Mouse (HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 P53 R175H Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 P53 R175H Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 P53 R175H Complex Protein, Human (HEK293, His-Avi), has molecular weight of 51-60 kDa.
HLA-A*1101as, a pivotal MHCI molecule, presents viral and tumor-derived peptides, guiding T cell immune responses against infected or transformed cells. Collaborating with B2M, it displays a diverse peptide repertoire. Both the presented peptide and MHCI contribute to antigen recognition specificity. HLA-A*1101 typically presents 8 to 13 amino acid intracellular peptides, binding different peptides with allele-specific motifs. It plays a crucial role in controlling infections, presenting immunodominant epitopes from HIV-1, EBV, HBV, and contributing to the immune response against SARS-CoV-2. HLA-A*1101 LMP2 Complex Protein, Human (SSCSSCPLTK, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and SSCSSCPLTK peptide. HLA-A*1101 LMP2 Complex Protein, Human (SSCSSCPLTK, HEK293, His-Avi), has molecular weight of 51-60 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. Chimeric HLA-A*0201 LMP2 Protein, Human&Mouse (HEK293, His-Avi) is the recombinant mouse-derived Chimeric HLA-A*0201 LMP2 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. Chimeric HLA-A*0201 LMP2 Protein, Human&Mouse (HEK293, His-Avi), has molecular weight of 52-65 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 P53 WT Complex Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 P53 WT Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 P53 WT Complex Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 51-60 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 LMP2 Complex Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 LMP2 Complex Tetramer protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 LMP2 Complex Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 LMP2 Complex Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 LMP2 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 LMP2 Complex Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 51-60 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 P53 WT Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 P53 WT Tetramer protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 P53 WT Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 LMP2 Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 LMP2 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 LMP2 Complex Protein, Human (HEK293, His-Avi), has molecular weight of 52-56 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 P53 WT Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 P53 WT protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 P53 WT Protein, Human (HEK293, His-Avi), has molecular weight of 52-62 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. Chimeric HLA-A*0201 WT-1 Complex Tetramer Protein, Human&Mouse (HEK293, His-Avi) is the recombinant mouse-derived Chimeric HLA-A*0201 WT-1 Complex Tetramer protein, expressed by HEK293 , with C-Avi, C-His labeled tag. Chimeric HLA-A*0201 WT-1 Complex Tetramer Protein, Human&Mouse (HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. Chimeric HLA-A*0201 WT-1 Complex Protein, Human&Mouse (HEK293, His-Avi) is the recombinant mouse-derived Chimeric HLA-A*0201 WT-1 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. Chimeric HLA-A*0201 WT-1 Complex Protein, Human&Mouse (HEK293, His-Avi), has molecular weight of 51-60 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 AFP Complex Protein, Human (Biotinylated, PLFQVPEPV, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 AFP Complex protein, expressed by HEK293, with C-Avi, C-His labeled tag. HLA-A*0201 AFP Complex Protein, Human (Biotinylated, PLFQVPEPV, HEK293, His-Avi), has molecular weight of 53-63 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 AFP Complex Protein, Human (Biotinylated, FMNKFIYEI, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 AFP Complex protein, expressed by HEK293, with C-Avi, C-His labeled tag. HLA-A*0201 AFP Complex Protein, Human (Biotinylated, FMNKFIYEI, HEK293, His-Avi), has molecular weight of 53-63 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 WT-1 Complex Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 WT-1 Complex Tetramer protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 WT-1 Complex Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 WT-1 Complex Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 WT-1 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 WT-1 Complex Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 55-60 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 AFP Complex Tetramer Protein, Human (PLFQVPEPV, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 AFP Complex Tetramer protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 AFP Complex Tetramer Protein, Human (PLFQVPEPV, HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 AFP Complex Tetramer Protein, Human (FMNKFIYEI, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 AFP Complex Tetramer protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 AFP Complex Tetramer Protein, Human (FMNKFIYEI, HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 WT-1 Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 WT-1 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 WT-1 Complex Protein, Human (HEK293, His-Avi), has molecular weight of 52-60 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 AFP Complex Protein, Human (PLFQVPEPV, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 AFP Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 AFP Complex Protein, Human (PLFQVPEPV, HEK293, His-Avi), has molecular weight of 55-60 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 Survivin Complex Protein, Human (Biotinylated, LMLGEFLKL, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 Survivin Complex protein, expressed by HEK293, with C-Avi, C-His labeled tag. HLA-A*0201 Survivin Complex Protein, Human (Biotinylated, LMLGEFLKL, HEK293, His-Avi), has molecular weight of 55-63 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 Survivin Complex Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 Survivin Complex Tetramer protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 Survivin Complex Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 Survivin Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 Survivin Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 Survivin Complex Protein, Human (HEK293, His-Avi), has molecular weight of 53-60 kDa.
B2M is a component of MHC class I complexes that present peptide antigens to the immune system. HLA-A*0201 NY-ESO-1 complex Protein, Human (HEK293, His) is the recombinant human-derived HLA-A*0201 NY-ESO-1 complex protein, expressed by HEK293 , with C-10*His labeled tag. HLA-A*0201 NY-ESO-1 complex Protein, Human (HEK293, His), has molecular weight of 55-60 kDa.
The HLA-E*0103 complex is a nonclassical major histocompatibility class Ib molecule that is critical for immune self-non-self discrimination. It selectively binds the VL9 peptide from classical MHC class Ia molecules, forming a complex with B2M. HLA-E*0103 Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-E*0103 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VMAPRTLVL peptide. HLA-E*0103 Complex Protein, Human (HEK293, His-Avi), has molecular weight of 52-65 kDa.
The HLA-E*0103 Complex, a non-classical major histocompatibility class Ib molecule, is crucial for immune self-nonself discrimination. It selectively binds VL9 peptides from classical MHC class Ia molecules, forming a complex with B2M. This complex acts as a ligand for KLRD1-KLRC1 on NK cells, facilitating immune monitoring. Under stress, HLA-E*0103 binds stress-induced chaperone peptides and HLA-G peptides, influencing NK cell activation and contributing to adaptive NK cell functions during pregnancy. Additionally, it presents pathogen-derived peptides to CD8-positive T cells, triggering an antimicrobial immune response. HLA-E*0103 Complex Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-E*0103 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-His, C-Avi labeled tag and VMAPRTLVL peptide. HLA-E*0103 Complex Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 52-60 kDa.
The HLA-E*0103 Complex, a non-classical major histocompatibility class Ib molecule, is crucial for immune self-nonself discrimination. It selectively binds VL9 peptides from classical MHC class Ia molecules, forming a complex with B2M. This complex acts as a ligand for KLRD1-KLRC1 on NK cells, facilitating immune monitoring. Under stress, HLA-E*0103 binds stress-induced chaperone peptides and HLA-G peptides, influencing NK cell activation and contributing to adaptive NK cell functions during pregnancy. Additionally, it presents pathogen-derived peptides to CD8-positive T cells, triggering an antimicrobial immune response. HLA-E*0103 Complex Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-E*0103 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VMAPRTLVL peptide. HLA-E*0103 Complex Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.
The HLA-E*0103 Complex, a non-classical major histocompatibility class Ib molecule, is crucial for immune self-nonself discrimination. It selectively binds VL9 peptides from classical MHC class Ia molecules, forming a complex with B2M. This complex acts as a ligand for KLRD1-KLRC1 on NK cells, facilitating immune monitoring. Under stress, HLA-E*0103 binds stress-induced chaperone peptides and HLA-G peptides, influencing NK cell activation and contributing to adaptive NK cell functions during pregnancy. Additionally, it presents pathogen-derived peptides to CD8-positive T cells, triggering an antimicrobial immune response. HLA-E*0103 Complex Tetramer Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-E*0103 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and VMAPRTLVL peptide. HLA-E*0103 Complex Tetramer Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-G, a non-classical major histocompatibility class Ib molecule, crucially regulates immunity at the maternal-fetal interface. Partnered with B2M, it forms a complex selectively binding self-peptides, fostering maternal-fetal tolerance through interactions with KIR2DL4, LILRB1, and LILRB2 receptors. Engagement triggers NK cell senescence, induces regulatory T cell differentiation, and balances tolerance and antiviral immunity. HLA-G actively contributes to immune modulation at the maternal-fetal interface, showcasing its multifaceted role in promoting fetal development while maintaining immune balance. HLA-G Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-G Protein and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and RIIPRHLQL peptide. HLA-G Complex Protein, Human (HEK293, His-Avi), has molecular weight of 51-60 kDa.
HLA-G, a non-classical major histocompatibility class Ib molecule, crucially regulates immunity at the maternal-fetal interface. Partnered with B2M, it forms a complex selectively binding self-peptides, fostering maternal-fetal tolerance through interactions with KIR2DL4, LILRB1, and LILRB2 receptors. Engagement triggers NK cell senescence, induces regulatory T cell differentiation, and balances tolerance and antiviral immunity. HLA-G actively contributes to immune modulation at the maternal-fetal interface, showcasing its multifaceted role in promoting fetal development while maintaining immune balance. HLA-G Protein, Human (C66S, His-Avi) is the recombinant human-derived HLA-G protein, expressed by E. coli , with C-Avi, C-His labeled tag and C66S mutation. The total length of HLA-G Protein, Human (C66S, His-Avi) is 281 a.a., with molecular weight of 36-42 kDa.
HLA-A*0201 WT-1 Complex Protein, a member of the MHC class I family, is crucial for immune function, presenting antigenic peptides to cytotoxic T lymphocytes. Associated with the HLA-A*0201 allele, this protein contributes to immune surveillance and defense mechanisms. In antigen presentation, HLA-A*0201 WT-1 Complex Protein aids in recognizing and eliminating abnormal or infected cells, emphasizing its significance in maintaining immune homeostasis. HLA-G Complex Protein, Cynomolgus (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-G and B2M/Beta-2 microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and RIIPRHLQL peptide. HLA-G Complex Protein, Cynomolgus (HEK293, His-Avi), has molecular weight of 55-65 kDa.
HLA-A*0201 WT-1 Complex Protein, a member of the MHC class I family, is crucial for immune function, presenting antigenic peptides to cytotoxic T lymphocytes. Associated with the HLA-A*0201 allele, this protein contributes to immune surveillance and defense mechanisms. In antigen presentation, HLA-A*0201 WT-1 Complex Protein aids in recognizing and eliminating abnormal or infected cells, emphasizing its significance in maintaining immune homeostasis. HLA-G Complex Tetramer Protein, Cynomolgus (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-G and B2M/Beta-2 microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and RIIPRHLQL peptide. HLA-G Complex Tetramer Protein, Cynomolgus (HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-G, a non-classical major histocompatibility class Ib molecule, crucially regulates immunity at the maternal-fetal interface. Partnered with B2M, it forms a complex selectively binding self-peptides, fostering maternal-fetal tolerance through interactions with KIR2DL4, LILRB1, and LILRB2 receptors. Engagement triggers NK cell senescence, induces regulatory T cell differentiation, and balances tolerance and antiviral immunity. HLA-G actively contributes to immune modulation at the maternal-fetal interface, showcasing its multifaceted role in promoting fetal development while maintaining immune balance. HLA-G Complex Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-G Protein and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and RIIPRHLQL peptide. HLA-G Complex Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 51-60 kDa.
HLA-G, a non-classical major histocompatibility class Ib molecule, crucially regulates immunity at the maternal-fetal interface. Partnered with B2M, it forms a complex selectively binding self-peptides, fostering maternal-fetal tolerance through interactions with KIR2DL4, LILRB1, and LILRB2 receptors. Engagement triggers NK cell senescence, induces regulatory T cell differentiation, and balances tolerance and antiviral immunity. HLA-G actively contributes to immune modulation at the maternal-fetal interface, showcasing its multifaceted role in promoting fetal development while maintaining immune balance. HLA-G Complex Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-G Protein and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and RIIPRHLQL peptide. HLA-G Complex Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-G, a non-classical major histocompatibility class Ib molecule, crucially regulates immunity at the maternal-fetal interface. Partnered with B2M, it forms a complex selectively binding self-peptides, fostering maternal-fetal tolerance through interactions with KIR2DL4, LILRB1, and LILRB2 receptors. Engagement triggers NK cell senescence, induces regulatory T cell differentiation, and balances tolerance and antiviral immunity. HLA-G actively contributes to immune modulation at the maternal-fetal interface, showcasing its multifaceted role in promoting fetal development while maintaining immune balance. HLA-G Complex Tetramer Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-G Protein and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and RIIPRHLQL peptide. HLA-G Complex Tetramer Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 260-265 kDa.
The HLA-G, part of the MHC class I family, is pivotal in immune regulation by presenting antigens to cytotoxic T cells and natural killer cells. Distinct from other MHC class I molecules, it shows limited polymorphism and tissue-specific expression, including in immune-privileged sites and the placenta. Linked to immune tolerance, its expression guards against excessive immune responses. Investigating HLA-G mechanisms offers insights into immune-related disorders and potential therapeutic strategies for immune response modulation. HLA-G Complex Tetramer Protein, Rhesus Macaque (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-G and B2M/Beta-2 microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and RIIPRHLQL peptide. HLA-G Complex Tetramer Protein, Rhesus Macaque (HEK293, His-Avi), has molecular weight of 260-265 kDa.
HLA-G is a nonclassical major histocompatibility class Ib molecule that is critical for immune regulation at the maternal-fetal interface. It cooperates with B2M to form a complex that selectively binds self-peptides to promote maternal-fetal tolerance by interacting with KIR2DL4, LILRB1, and LILRB2 receptors. PE-Labeled HLA-G Complex Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-G Protein and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and RIIPRHLQL peptide. PE-Labeled HLA-G Complex Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.
B2 microglobulin; DADB-15K14.8; HLA 6.0; HLA class I histocompatibility antigen alpha chain G; Major histocompatibility complex class I G; MHC class I antigen; MHC class I antigen G; MHC G; T-cell A locus; TCA
HLA-G is a nonclassical major histocompatibility class Ib molecule that is critical for immune regulation at the maternal-fetal interface. It cooperates with B2M to form a complex that selectively binds self-peptides to promote maternal-fetal tolerance by interacting with KIR2DL4, LILRB1, and LILRB2 receptors. HLA-G Protein, Human (HEK293, His) is the recombinant human-derived HLA-G protein, expressed by HEK293 , with N-His labeled tag. The total length of HLA-G Protein, Human (HEK293, His) is 314 a.a., with molecular weight of ~39.6 kDa.
HLA-B Protein, a member of the major histocompatibility complex (MHC) class I family, is acknowledged. HLA-B Protein, Human (His) is the recombinant human-derived HLA-B protein, expressed by E. coli , with N-6*His labeled tag. The total length of HLA-B Protein, Human (His) is 284 a.a., with molecular weight of ~36.8 kDa.
HLA-B Protein, a member of the major histocompatibility complex (MHC) class I family, is acknowledged. HLA-B Protein, Human (N-His) is the recombinant human-derived HLA-B protein, expressed by E. coli , with N-6*His labeled tag. The total length of HLA-B Protein, Human (N-His) is 284 a.a., with molecular weight of ~33.33 kDa.
The HLA-DPA1 protein is critical in the immune system, binding antigens in the endocytic pathway of APCs and presenting them to the cell surface for recognition by CD4 T cells. The peptide binding cleft can accommodate peptides of 10-30 residues, mainly resulting from protein degradation. HLA-DPA1 Protein, Human (His) is the recombinant human-derived HLA-DPA1 protein, expressed by E. coli , with N-His labeled tag. The total length of HLA-DPA1 Protein, Human (His) is 194 a.a., with molecular weight of ~26.3 kDa.
MICB Protein, a heavily glycosylated ligand for NKG2D receptor, triggers cytolytic response in immune cells. It resembles MHC class I molecules but lacks association with beta-2-microglobulin or peptide binding. Alternative splicing leads to multiple transcript variants. MICB is widely expressed, especially in lymph nodes and bone marrow, highlighting its immune response role in diverse physiological contexts. MICB Protein, Human (HEK293, His) is the recombinant human-derived MICB protein, expressed by HEK293 , with C-His, C-6*His labeled tag. The total length of MICB Protein, Human (HEK293, His) is 276 a.a., with molecular weight of ~45 kDa.
MICA is a ligand for the stress signaling protein and natural killer (NK) cell activating receptor KLRK1/NKG2D. Tumor cells shed the expressed MICA protein and undergo immune evasion. MICA Protein, Human (HEK293, Fc) is the recombinant human-derived MICA protein, expressed by HEK293 , with C-hFc labeled tag. The total length of MICA Protein, Human (HEK293, Fc) is 285 a.a., with molecular weight of 85-110 kDa.
In contrast to antigen presentation, MICB proteins serve as stress-induced autoantigens and are recognized by γδ T cells. As a ligand for the KLRK1/NKG2D receptor, binding of MICB results in cell lysis. MICB Protein, Human (HEK293, His-Fc) is the recombinant human-derived MICB protein, expressed by HEK293 , with C-hFc, C-His labeled tag. The total length of MICB Protein, Human (HEK293, His-Fc) is 298 a.a., with molecular weight of 80-90 kDa.
HLA-C Protein, part of the MHC class I family, is crucial for immune system functions, presenting antigens to cytotoxic T cells. In this family, HLA-C is involved in regulating immune responses and recognizing foreign substances. Further exploration is needed to reveal specific functions and implications within the broader MHC class I family, emphasizing its significance in immune surveillance and host defense mechanisms. HLA-C Protein, Human (His) is the recombinant human-derived HLA-C protein, expressed by E. coli , with N-6*His labeled tag. The total length of HLA-C Protein, Human (His) is 284 a.a., with molecular weight of ~36.7 kDa.
B2 microglobulin; DADB-15K14.8; HLA 6.0; HLA class I histocompatibility antigen alpha chain G; HLA class I histocompatibility antigen; alpha chain G; HLA class I molecule; HLA G; HLA G antigen; HLA G histocompatibility antigen class I G; HLA G3; HLA-G; HLA-G histocompatibility antigen; class I; HLA60; HLAG; HLAG_HUMAN; Major histocompatibility complex class I G; MHC class I antigen; MHC class I antigen G; MHC G; T-cell A locus; TCA
HLA-G is a nonclassical major histocompatibility class Ib molecule that is critical for immune regulation at the maternal-fetal interface. It cooperates with B2M to form a complex that selectively binds self-peptides to promote maternal-fetal tolerance by interacting with KIR2DL4, LILRB1, and LILRB2 receptors. HLA-G Protein, Human (His-SUMO) is the recombinant human-derived HLA-G protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of HLA-G Protein, Human (His-SUMO) is 314 a.a., with molecular weight of ~51.6 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 GP100 Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 GP100 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 GP100 Complex Protein, Human (HEK293, His-Avi), has molecular weight of 52-62 kDa.
HLA-A*0201 WT-1 Complex Protein, a member of the MHC class I family, is crucial for immune function, presenting antigenic peptides to cytotoxic T lymphocytes. Associated with the HLA-A*0201 allele, this protein contributes to immune surveillance and defense mechanisms. In antigen presentation, HLA-A*0201 WT-1 Complex Protein aids in recognizing and eliminating abnormal or infected cells, emphasizing its significance in maintaining immune homeostasis. HLA-G Complex Protein, Cynomolgus (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-G and B2M/Beta-2 microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and RIIPRHLQL peptide. HLA-G Complex Protein, Cynomolgus (Biotinylated, HEK293, His-Avi), has molecular weight of 55-65 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 GP100 Complex Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 GP100 Complex Tetramer protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 GP100 Complex Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.
KIR2DS1, on NK cells, acts as a receptor for specific HLA-C alleles, like w6, without inhibiting NK cell activity. Interacting with the adapter protein TYROBP/DAP12, their collaboration enhances KIR2DS1 stability at the cell surface. This dynamic interplay highlights the intricate regulatory mechanisms associated with KIR2DS1, contributing to the modulation of NK cell responses. KIR2DS1 Protein, Human (P.pastoris, His) is the recombinant human-derived KIR2DS1 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of KIR2DS1 Protein, Human (P.pastoris, His) is 224 a.a., with molecular weight of ~34 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 GP100 Complex Protein, Human (Biotinylated, YLEPGPVTA, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 GP100 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 GP100 Complex Protein, Human (Biotinylated, YLEPGPVTA, HEK293, His-Avi), has molecular weight of 52-62 kDa.
MICA is a ligand for the stress signaling protein and natural killer (NK) cell activating receptor KLRK1/NKG2D. Tumor cells shed the expressed MICA protein and undergo immune evasion. MICA Protein, Human (285a.a, HEK293, His) is the recombinant human-derived MICA protein, expressed by HEK293 , with C-6*His labeled tag. The total length of MICA Protein, Human (285a.a, HEK293, His) is 285 a.a., with molecular weight of ~60.0 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 MAGE-A4 Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 MAGE-A4 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 MAGE-A4 Complex Protein, Human (HEK293, His-Avi), has molecular weight of 52-60 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 MAGE-A4 Complex Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 MAGE-A4 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 MAGE-A4 Complex Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 52-60 kDa.
HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 MAGE-A4 Complex Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 MAGE-A4 Complex Tetramer protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 MAGE-A4 Complex Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.
KIR2DS3, present on NK cells, selectively recognizes HLA-C alleles. In contrast to inhibitory KIRs, KIR2DS3 lacks inhibitory effects on NK cell activity. Its role is likely in activating or modulating NK cell functions, contributing to the nuanced balance of signals regulating the immune response. KIR2DS3 Protein, Human (P.pastoris, His) is the recombinant human-derived KIR2DS3 protein, expressed by P. pastoris , with N-His labeled tag. The total length of KIR2DS3 Protein, Human (P.pastoris, His) is 224 a.a., with molecular weight of ~26.7 kDa.
rHuCD158d, His; Killer Cell Immunoglobulin-Like Receptor 2DL4; CD158 Antigen-Like Family Member D; KIR-103AS; MHC Class I NK Cell Receptor KIR103AS; CD158d; KIR2DL4; KIR103AS
CD158d/KIR2DL4 Protein, Human (HEK293, His) is a recombinant human CD158d expressed in HEK 293 cells with a His tag at the N-terminus. CD158d/KIR2DL4 Protein is an NK cell-activating receptor with inhibitory potential.
Killer cell immunoglobulin-like receptor 2DL2; CD158 antigen-like family member B1; MHC class I NK cell receptor; NKAT-6; p58 NK receptor CL-43; CD158b1; KIR2DL2; CD158B1; NKAT6
KIR2DL2/CD158b1, found on NK cells, functions as a receptor for HLA-Cw1, Cw3, Cw7, and Cw8 allotypes. Its key role is to inhibit NK cell activity, serving as a regulator to prevent cellular lysis. Interacting with specific HLA-C molecules, KIR2DL2/CD158b1 contributes to the delicate balance of inhibitory signals in the immune system, shaping the responsiveness of NK cells to potential targets. KIR2DL2/CD158b1 Protein, Human (HEK293, His-Avi) is the recombinant human-derived KIR2DL2/CD158b1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of KIR2DL2/CD158b1 Protein, Human (HEK293, His-Avi) is 224 a.a., with molecular weight of 45-50 kDa.
Killer cell immunoglobulin-like receptor 2DL2; CD158 antigen-like family member B1; MHC class I NK cell receptor; NKAT-6; p58 NK receptor CL-43; CD158b1; KIR2DL2; CD158B1; NKAT6
KIR2DL2/CD158b1, found on NK cells, functions as a receptor for HLA-Cw1, Cw3, Cw7, and Cw8 allotypes. Its key role is to inhibit NK cell activity, serving as a regulator to prevent cellular lysis. Interacting with specific HLA-C molecules, KIR2DL2/CD158b1 contributes to the delicate balance of inhibitory signals in the immune system, shaping the responsiveness of NK cells to potential targets. KIR2DL2/CD158b1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived KIR2DL2/CD158b1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of KIR2DL2/CD158b1 Protein, Human (Biotinylated, HEK293, His-Avi) is 224 a.a., with molecular weight of 45-60 kDa.
KIR2DL3, found on NK cells, selectively recognizes HLA-C alleles like HLA-Cw1, HLA-Cw3, and HLA-Cw7. Its interaction leads to inhibitory effects, preventing NK cell activity and cell lysis. KIR2DL3's association with ARRB2 underscores its role in cellular signaling pathways, intricately modulating NK cell functions. KIR2DL3 Protein, Human (HEK293, His) is the recombinant human-derived KIR2DL3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of KIR2DL3 Protein, Human (HEK293, His) is 224 a.a., with molecular weight of 35-50 kDa.
CRTAM/CD355 Protein is an immunoglobulin-superfamily transmembrane protein, and is a member of nectin-like protein superfamily. CRTAM is also expressed on activated human NK cells, CD8+ T cells and a subset of CD4+ T cells. CRTAM takes part in cellular adhesion, polarity, and proliferation. CRTAM also regulates lymphocyte function, and promotes TCD8+ cell adhesion and retention within the lymph node. Furthermore, CRTAM can interact with Necl-2, and promotes cytotoxicity of NK cells and IFN-γ secretion of CD8+ T cells in vitro, and NK cell-mediated rejection of tumors expressing Necl-2 in vivosup>[3]. CRTAM/CD355 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CRTAM/CD355 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CRTAM/CD355 Protein, Cynomolgus (HEK293, His) is 270 a.a., with molecular weight of 50-60 kDa.
The CRTAM/CD355 protein is a key mediator of heterophilic intercellular adhesion and complexly regulates the activation, differentiation, and tissue retention of T cell subsets. Its interaction with CADM1 promotes NK cell cytotoxicity and CD8+ T cell secretion of IFNG, thus contributing to NK cell-mediated tumor rejection. CRTAM/CD355 Protein, Human (HEK293, His) is the recombinant human-derived CRTAM/CD355 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CRTAM/CD355 Protein, Human (HEK293, His) is 269 a.a., with molecular weight of 58-64 kDa.
Pristane-d40 is the deuterium labeled Pristane[1]. Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil[2]. Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat[3].
