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Results for "

MMP

" in MedChemExpress (MCE) Product Catalog:

By Targets:	MMP (275) Adenosine Receptor (1) Adrenergic Receptor (1) Akt (10) Aminopeptidase (1) Amyloid-β (2) Angiotensin-converting Enzyme (ACE) (2) Antibiotic (13) AP-1 (2) Apoptosis (54) Atg8/LC3 (1) Autophagy (8) Bacterial (20) Bcl-2 Family (4) Biochemical Assay Reagents (1) c-Met/HGFR (1) Calcium Channel (2) Carbonic Anhydrase (1) Caspase (4) Cathepsin (3) CDK (3) Chloride Channel (2) Cholinesterase (ChE) (2) ClpP (1) COX (8) Deubiquitinase (1) Drug Metabolite (1) E1/E2/E3 Enzyme (1) EBI2/GPR183 (1) EGFR (4) Endogenous Metabolite (10) ERK (8) FAK (4) Ferroptosis (1) Fluorescent Dye (5) Fungal (3) Glucocorticoid Receptor (3) GLUT (1) GSK-3 (1) HIV (3) HIV Integrase (1) HIV Protease (3) HSV (2) HuR (1) iGluR (1) Interleukin Related (5) Isotope-Labeled Compounds (5) JAK (1) JNK (5) Keap1-Nrf2 (2) Leukotriene Receptor (1) MALT1 (1) MDM-2/p53 (1) Microtubule/Tubulin (4) Mitochondrial Metabolism (2) Mixed Lineage Kinase (2) mTOR (4) NF-κB (16) NO Synthase (3) Nucleoside Antimetabolite/Analog (1) Oxidative Phosphorylation (3) P-glycoprotein (1) P2Y Receptor (1) p38 MAPK (6) Parasite (10) PARP (1) Phosphodiesterase (PDE) (1) PI3K (4) PKA (1) PKC (1) Potassium Channel (1) PPAR (1) Proteasome (2) Pyroptosis (1) RANKL/RANK (4) Ras (1) Reactive Oxygen Species (18) RIP kinase (2) SARS-CoV (4) Small Interfering RNA (siRNA) (44) Src (2) TGF-beta/Smad (1) TNF Receptor (10) Toll-like Receptor (TLR) (7) VEGFR (2) Wnt (5) β-catenin (5)
By Research Areas:	Cancer (186) Cardiovascular Disease (20) Endocrinology (4) Infection (34) Inflammation/Immunology (124) Metabolic Disease (18) Neurological Disease (19)
Oligonucleotides:	Nucleosides and their Analogs (1) Pre-designed siRNA Sets (44) siRNAs (44)

390

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: MMP

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-153563

MMP-7-IN-2	MMP	Others
MMP-7-IN-2 (compound 16) is a selective inhibitor of *MMP7* with an IC₅₀ value of 16 nM .

HY-119423

MMP Inhibitor II	MMP	Cancer
MMP Inhibitor II (compound 4e) is a potent, reversible pan-MMP inhibitor with IC₅₀ values of 24 nM, 18.4 nM, 30 nM, and 2.7 nM for MMP-1,MMP-3, MMP-7, and MMP-9, respectively .

HY-147745

MMP2-IN-2	MMP	Cancer
MMP2-IN-2 (compound 42) is a potent and selective *MMP-2* (matrix metalloproteinases) inhibitor, with an IC₅₀ of 4.2 μM. MMP2-IN-2 also shows inhibitory activity against *MMP-13, MMP-9* and *MMP-8, with IC₅₀* values of 12, 23.3, and 25 μM, respectively .

HY-156430

MMP-7-IN-3	MMP	Cancer
MMP-7-IN-3 is a potent and selective inhibitor of *MMP-7. MMP*-7-IN-3 suppresses kidney fibrosis progression in a mouse model with unilateral ureteral obstruction .

HY-146754

MMP2-IN-1 1 Publications Verification	MMP Apoptosis	Cancer
MMP2-IN-1 is a moderate potenet *MMP2* inhibitor with IC₅₀ of 6.8 µM. MMP2-IN-1 exhibits remarkable antiproliferative activity in certain cancer cells by arresting the cell cycle and inducing apoptosis .

HY-128026

MMP-9/MMP-13 Inhibitor I	MMP	Inflammation/Immunology
MMP-9/MMP-13 Inhibitor I is a potent *MMP-9* and *MMP-13* inhibitor with IC₅₀s of both 0.9 nM. MMP-9/MMP-13 Inhibitor I shows >20-folds selectivity for MMP-9/MMP-13 over other MMPs .

HY-116399

MMP-2/MMP-9-IN-1	MMP	Cancer
MMP-2/MMP-9-IN-1 is a highly selective, orally active and potent type IV collagenase (MMP-9 and *MMP-2) inhibitor with IC₅₀s of 0.24 and 0.31 μM for MMP-9 and MMP-2, respectively. MMP-2/MMP-9-IN-1 is orally active in animal models of tumor growth and metastasis. MMP-2/MMP*-9-IN-1 can be used for the research of cancer .

HY-P2179

MMP-1/MMP-9 Substrate, Fluorogenic	Fluorescent Dye MMP	Others
MMP-1/MMP-9 Substrate, Fluorogenic is a fluorogenic substrate for MMP-1 and MMP-9 .Ex/Em = 340/440 nm

HY-P2166

MMP3 inhibitor 3	MMP	Cancer
MMP3 inhibitor 3 is an inhibitor of *MMP3. MMP*3 inhibitor 3 can used to study breast cancer .

HY-161284

MMP-9/10-IN-1	MMP	Cancer
MMP-9/10-IN-1 (Compound 6b) is a potent dual *MMP-9/10* Inhibotor with IC₅₀s of 0.076 and 0.139 μM against NSCLC and A549 cells, respectively. MMP-9/10-IN-1 has anti-invasive and anti-angiogenic activities when in combination with Sorafenib (HY-10201) .

HY-P2682

MMP-8/MMP-26 Fluorogenic substrate	MMP	Metabolic Disease
MMP-8/MMP-26 Fluorogenic substrate (DNP-Pro-Leu-Ala-Tyr-Trp-Ala-Arg) is a matrix metalloproteinase-8 (MMP-8) fluorogenic substrate. MMP-8/MMP-26 Fluorogenic substrate can be used for the research of atherosclerosis, pulmonary fibrosis, and sepsis .

HY-128133

MMP-8 inhibitor-1 MMP8-I	MMP	Cancer
MMP-8 inhibitor-1 (compound 21), a hydroxamic acid derivative, is a potent *MMP-8* inhibitor without significant oral bioavailability .

HY-P2414

MMP-13 Substrate	MMP	Inflammation/Immunology
MMP-13 Substrate is a substrate of MMP-13. MMP-13 Substrate can be used for the research of osteoarthritis (OA) .

HY-14155

MMP145	MMP	Inflammation/Immunology
MMP145 (compound 27) is a potent, selective and orally active *MMP-12* inhibitor. MMP145 is effective in inflammation and asthma reasearch .

HY-116302

MMP-9-IN-9	MMP	Neurological Disease Inflammation/Immunology
MMP-9-IN-9 (compound 4f) is a slective *MMP-9* inhibitor with an IC₅₀ of 5 nM. MMP-9-IN-9 shows selective for MMP-9 over MMP-1 and MMP-13. MMP-9-IN-9 shows strong anti-inflammatory and neuroprotective effects .

HY-130076

MMP-2 Inhibitor II	MMP	Cancer
MMP-2 Inhibitor II (compound 2) is a selective *MMP-2* inhibitor. The Kinetic parameters for MMP inhibition are 2.4 μM (MMP-2), 45 μM (MMP-1), and 379 μM (MMP-7), respectively .

HY-146218

MMP-9-IN-5	MMP Akt Apoptosis	Cancer
MMP-9-IN-5 is a *MMP-9* inhibitor (IC₅₀: 4.49 nM) that forms hydrogen bond with MMP-9. MMP-9-IN-5 also inhibits _AKT activity (IC₅₀: 1.34 nM). MMP-9-IN-5 shows cell cytotoxicity and induces cell apoptosis. MMP-9-IN-5 can be used in the research of cancers .

HY-146216

MMP-9-IN-3	MMP Akt Apoptosis	Cancer
MMP-9-IN-3 is a *MMP-9* inhibitor (IC₅₀: 5.56 nM) that forms hydrogen bond with MMP-9. MMP-9-IN-3 also inhibits AKT activity (IC₅₀: 2.11 nM). MMP-9-IN-3 shows cell cytotoxicity and induces cell apoptosis. MMP-9-IN-3 can be used in the research of cancers .

HY-147746

MMP2-IN-3	MMP	Cancer
MMP2-IN-3 (compound 2) is a potent *MMP-2* (matrix metalloproteinases) inhibitor, with an IC₅₀ of 31 μM. MMP2-IN-3 also shows inhibitory activity against *MMP-9* and *MMP-8, with IC₅₀* values of 26.6, and 32 μM, respectively .

HY-146217

MMP-9-IN-4	MMP Akt Apoptosis	Cancer
MMP-9-IN-4 is a *MMP-9* inhibitor (IC₅₀: 7.46 nM) that has H-π interactions with MMP-9. MMP-9-IN-4 also inhibits _AKT activity (IC₅₀: 8.82 nM). MMP-9-IN-4 shows cell cytotoxicity and induces cell apoptosis. MMP-9-IN-4 can be used in the research of cancers .

HY-P2414A

MMP-13 Substrate TFA	MMP	Inflammation/Immunology
MMP-13 Substrate TFA is a substrate of MMP-13. MMP-13 Substrate TFA can be used for the research of osteoarthritis (OA) .

HY-153913

MMP-9-IN-7	MMP	Inflammation/Immunology
MMP-9-IN-7 is a potent *MMP9* inhibitor with an IC₅₀ of 0.52 μM in proMMP9/MMP3 P126 activation assay. MMP-9-IN-7 is extracted from patent WO2012162468 (example 59), and can be used for MMP9/MMP13 mediated syndrome research .

HY-135232

MMP-9-IN-1 5+ Cited Publications	MMP	Cancer
MMP-9-IN-1 is a specific matrix metalloproteinase-9 (MMP-9) inhibitor, which selectively target the hemopexin (PEX) domain of MMP-9, but not other MMPs .

HY-151540

MMP-7-IN-1	MMP	Cancer
MMP-7-IN-1 is a potent and selective inhibitor of *MMP-7* over MMP-1, -2, -3, -8, -9, -13 with an IC₅₀ value of 10 nM. MMP-7 is a potential target for diseases including cancer and fibrosis .

HY-122624

MMP13-IN-2	MMP	Inflammation/Immunology
MMP13-IN-2 is a potent, selective and orally active *MMP-13* inhibitor. MMP13-IN-2 exhibits excellent potency for MMP-13 (IC₅₀=0.036 nM) and selectivities (greater than 1,500-fold) over MMP-1, 3, 7, 8, 9, 14, and TACE. MMP13-IN-2 has the ability to block the release of collagen from cartilage in vitro. MMP13-IN-2 has the potential for collagenase related disease research .

HY-161707

MMP2-IN-4	MMP	Cancer
MMP2-IN-4 (compound 3h) is a potent *MMP2* inhibitor. MMP2-IN-4 inhibits *MMP2, MMP9* and *MMP12* with IC₅₀s of 266.74, 402.75 and 1237.39 nM, respectively .

HY-154868

MMP-13-IN-1	MMP	Cardiovascular Disease Cancer
MMP-13-IN-1 is a potent and selective inhibitor of *MMP-13* with a IC₅₀ value of 16 nM. MMP-13-in-1 can be used for atherosclerosis research .

HY-104024

MMP-9-IN-10	MMP	Inflammation/Immunology Cancer
MMP-9-IN-10 (compound 4f) is a selective *MMP-9* inhibitor with an IC₅₀ of 5 nM. MMP-9-IN-10 can be used for cancer and inflammatory research .

HY-112546

MMP-2 Inhibitor I	MMP	Cancer
MMP-2 Inhibitor I (OA-Hy) is a potent MMP-2 inhibitor with a K_i of 1.7 μM .

HY-149378

MMP13-IN-5	MMP	Metabolic Disease
MMP13-IN-5 (compound 13m) is a potent and selective inhibitor of *MMP-2/MMP-13* (IC₅₀=3.6 μM/14.6 μM)，involved in osteoarthritis (OA) .

HY-152092

MMP-1-IN-1	MMP	Cancer
MMP-1-IN-1 (Compound 6) is a highly potent *MMP-1* inhibitor with an IC₅₀ of 0.034 μM .

HY-130391

MMP12-IN-3	MMP	Inflammation/Immunology
MMP12-IN-3 (compound 32) is a potent *MMP12* inhibitor with an IC₅₀ value of 4.9 nM. MMP12-IN-3 has the potential for the research of chronic respiratory diseases such as emphysema .

HY-161285

MMP-9/10-IN-2	MMP	Cancer
MMP-9/10-IN-2 (compound 6e) is a potent inhibitor of *MMP10 and MMP9, with IC₅₀* of 0.076 μM for *MMP*10, and 93.18% inhibition at 0.5 μM for *MMP9. MMP*-9/10-IN-2 plays an important role in anti-tumor .

HY-149377

MMP13-IN-4	MMP	Metabolic Disease
MMP13-IN-4 (compound 13) is a potent and selective inhibitor of *MMP-13* (IC₅₀=14.6 μM)，involved in osteoarthritis (OA) .

HY-149848

MMP-9-IN-6	MMP	Inflammation/Immunology
MMP-9-IN-6 (Compound 3g) is a *MMP-9* inhibitor with IC₅₀ value of 50 μM, which has good anti-ulcer effect .

HY-168560

MMP Inhibitor 4	MMP	Cancer
MMP Inhibitor 4 (compound 4 B) is a potent *MMP* inhibitor. MMP Inhibitor 4 shows antiproliferative activity. MMP Inhibitor 4 induces cell cycle arrest at subG1 phase. MMP Inhibitor 4 decreases the mRNA expression of MMP2, MMP9 and VEGFA .

HY-157138

MMP-9-IN-8	Others	Cancer
MMP-9-IN-8 (Compound 3) is an MMP-9 inhibitor with inhibitory activities of 42.16% and 58.28% at 10 μM and 50 μM concentrations, respectively. MMP-9-IN-8 has anti-cancer activity and can induce apoptosis in MCF-7 cells with an IC₅₀ value of 23.42 μM .

HY-147867

MMP-2/9-IN-1	MMP	Cancer
MMP-2/9-IN-1 (Compound 4a) is a potent dual *MMP-2* and *MMP-9* inhibitor with IC₅₀ values of 56 nM and 38 nM, respectively. MMP-2/9-IN-1 inhibits tumor growth, strongly induces cancer cell apoptosis, inhibits cell migration, and suppresses cell cycle progression leading to DNA fragmentation .

HY-162039

MMP-11-IN-1	MMP	Cancer
MMP-11-IN-1 (compound 9) is a new class of phosphinate prodrug. MMP-11-IN-1 is a glycosyl ester of RXP03 and improves blood–brain barrier (BBB) behavior .

HY-12093

MMP408	Others	Others
MMP408 is an active compound.

HY-114418

MMP3 inhibitor 1 1 Publications Verification	MMP	Cancer
MMP3 inhibitor 1 is a potent and highly selective *MMP-3* inhibitor with an IC₅₀ of 1 nM .

HY-124029

BI-4394 MMP13-IN-3	MMP	Inflammation/Immunology
BI-4394 (MMP13-IN-3) is a potent, selective, and orally active *MMP-13* inhibitor (IC₅₀=1 nM ) for the potential treatment of osteoarthritis . BI-4394 is >1000 selective over other MMPs .

HY-RS08516

MMP1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MMP1 Human Pre-designed siRNA Set A contains three designed siRNAs for MMP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MMP1 Human Pre-designed siRNA Set A MMP1 Human Pre-designed siRNA Set A

HY-RS08517

Mmp1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Mmp1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mmp1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Mmp1 Rat Pre-designed siRNA Set A Mmp1 Rat Pre-designed siRNA Set A

HY-RS08518

MMP10 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MMP10 Human Pre-designed siRNA Set A contains three designed siRNAs for MMP10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MMP10 Human Pre-designed siRNA Set A MMP10 Human Pre-designed siRNA Set A

HY-RS08519

Mmp10 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Mmp10 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mmp10 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Mmp10 Mouse Pre-designed siRNA Set A Mmp10 Mouse Pre-designed siRNA Set A

HY-RS08520

Mmp10 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Mmp10 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mmp10 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Mmp10 Rat Pre-designed siRNA Set A Mmp10 Rat Pre-designed siRNA Set A

HY-RS08521

MMP11 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MMP11 Human Pre-designed siRNA Set A contains three designed siRNAs for MMP11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MMP11 Human Pre-designed siRNA Set A MMP11 Human Pre-designed siRNA Set A

HY-RS08522

MMP12 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MMP12 Human Pre-designed siRNA Set A contains three designed siRNAs for MMP12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MMP12 Human Pre-designed siRNA Set A MMP12 Human Pre-designed siRNA Set A

HY-RS08523

Mmp12 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Mmp12 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mmp12 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Mmp12 Mouse Pre-designed siRNA Set A Mmp12 Mouse Pre-designed siRNA Set A