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Results for "

MYCN

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-112273
    CD532

    		Aurora Kinase Cancer
    CD532 is a potent Aurora A kinase inhibitor with an IC50 of 45 nM. CD532 has the dual effect of blocking Aurora A kinase activity and driving degradation of MYCN. CD532 also can directly interact with AURKA and induces a global conformational shift. CD532 can be used for the research of cancer .
    CD532
  • HY-112273A
    CD532 hydrochloride

    		Aurora Kinase Cancer
    CD532 hydrochloride is a potent Aurora A kinase inhibitor with an IC50 of 45 nM. CD532 hydrochloride has the dual effect of blocking Aurora A kinase activity and driving degradation of MYCN. CD532 hydrochloride also can directly interact with AURKA and induces a global conformational shift. CD532 hydrochloride can be used for the research of cancer .
    CD532 hydrochloride
  • HY-RS08884
    MYCN Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    MYCN Human Pre-designed siRNA Set A contains three designed siRNAs for MYCN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    MYCN Human Pre-designed siRNA Set A
    MYCN Human Pre-designed siRNA Set A
  • HY-156443
    YG1702

    		Aldehyde Dehydrogenase (ALDH) Cancer
    YG1702 is a potent ALDH18A1-specific inhibitor. YG1702 attenuates the growth of MYCN-amplified NB and down-regulates MYCN. YG1702 physically interacts with ALDH18A1 with a high affinity and might potentially affect its enzymatic activity .
    YG1702
  • HY-158062
    LC-1-40

    		PROTACs DNA/RNA Synthesis Apoptosis Cancer
    LC-1-40 is a PROTAC that selectively degrades NUDT1 (DC50=0.97 nM). LC-1-40 selectively inhibits MYCN-induced tumor growth in mouse models. LC-1-40 also induces nucleotide damage and apoptosis in MYCN-associated tumors. LC-1-40 can be used in cancer research . (Red: NUDT1 binder; Blue: CRBN ligand; Black: Linker).
    LC-1-40
  • HY-145765
    JQAD1

    		PROTACs Histone Acetyltransferase Apoptosis Caspase PARP Cancer
    JQAD1 is a CRBN-dependent PROTAC that selectively targets EP300 for degradation. JQAD1 suppresses EP300 expression and the H3K27ac modification. JQAD1 induces apoptosis. JQAD1 can be used in research of cancer .
    JQAD1
  • HY-152032
    LSD1-IN-23

    		Histone Demethylase Cancer
    LSD1-IN-23 is a competitive/non-competitive mixed inhibitor of lysine specific demethylase 1 (LSD1). LSD1-IN-23 has LSD1 inhibitory activity with an IC50 value of 0.58 μM. LSD1-IN-23 can be used for the research of neuroblastoma (NB) .
    LSD1-IN-23

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