Max

By Targets:	Apoptosis (3) Autophagy (4) Bacterial (1) c-Myc (11) CDK (1) FGFR (4) FLT3 (4) Fluorescent Dye (6) NO Synthase (2) PARP (1) PD-1/PD-L1 (1) PI3K (1) PKC (1) PROTACs (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (20) Cardiovascular Disease (1) Infection (1) Inflammation/Immunology (6) Metabolic Disease (1)
Click Chemistry:	Labeling and Fluorescence Imaging (2) Azide (1) Tetrazine (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-145723

MAX-40279	FLT3 FGFR	Inflammation/Immunology Cancer
MAX-40279 is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 has the potential for the research of acute myelogenous leukemia (AML) (extracted from patent WO2021180032) .

HY-145723B

MAX-40279 hemifumarate	FLT3 FGFR	Inflammation/Immunology Cancer
MAX-40279 hemifumarate is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 hemifumarate has the potential for the research of acute myelogenous leukemia (AML) (extracted from patent WO2021180032) .

HY-145723C

MAX-40279 hemiadipate	FLT3 FGFR	Inflammation/Immunology Cancer
MAX-40279 hemiadipate is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 hemiadipate has the potential for the research of acute myelogenous leukemia (AML) (extracted from patent WO2021180032) .

HY-153064

MAX-10181 PD-1/PD-L1-IN-30	PD-1/PD-L1	Cancer
MAX-10181 (PD-1/PD-L1-IN-30) is a PD-1/PD-L1 binding inhibitor, with an IC₅₀ value of 0.018 μM. MAX-10181 can be used for research of cancers and other related diseases .

HY-145723A

MAX-40279 hydrochloride	FLT3 FGFR	Inflammation/Immunology Cancer
MAX-40279 hydrochloride is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 hydrochloride has the potential for the research of acute myelogenous leukemia (AML) (extracted from patent WO2021180032) .

HY-RS08177

MAX Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MAX Human Pre-designed siRNA Set A contains three designed siRNAs for MAX gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MAX Human Pre-designed siRNA Set A MAX Human Pre-designed siRNA Set A

HY-134975

NY2267

c-Myc Cancer

NY2267 is a disruptor of Myc-Max interaction, with an IC₅₀ of 36.5 μM. NY2267 inhibits Myc- and Jun-induced transcriptional activation .

NY2267	c-Myc	Cancer
NY2267 is a disruptor of *Myc-Max* interaction, with an IC₅₀** of 36.5 μM. NY2267 inhibits Myc- and Jun-induced transcriptional activation .

HY-100669

Mycro 3 5 Publications Verification	c-Myc Autophagy	Cancer
Mycro 3 is an orally active, potent and selective inhibitor of *Myc-associated factor X (MAX) dimerization*. Mycro 3 also inhibit DNA binding of c-Myc . Mycro 3 could be used for the research of pancreatic cancer .

HY-N7273

Soyasaponin III	Apoptosis	Cancer
Soyasaponin III, a monodesmodic oleanane triterpenoid, is one of the main potentially bioactive saponins found in soy (Glycine max) and related products. Soyasaponin III can induce apoptosis in Hep-G2 cells .

HY-N6999

Soyasaponin Ac

Others Metabolic Disease

Soyasaponin Ac is a triterpenoid isolated from the seeds of Glycine max.

Soyasaponin Ac	Others	Metabolic Disease
Soyasaponin Ac is a triterpenoid isolated from the seeds of Glycine max.

HY-147291

VPC-70063	c-Myc PARP Apoptosis	Cancer
VPC-70063 is a potent *Myc-Max* inhibitor with an IC₅₀ value of 8.9 μM for Myc-Max transcriptional activity inhibition. VPC-70063 reduces UBE2C promotor activity and AR-V7 levels, and induces PARP cleavage. VPC-70063 induces apoptosis and blocks Myc-Max interactions with DNA. VPC-70063 can be used for researching anticancer .

HY-125636

Mycro1	Others	Cancer
Mycro1 is an inhibitor of c-Myc/Max dimer and DNA binding, with an IC₅₀ value of 30 μM for the inhibition of Myc/Max DNA binding activity. Mycro1 can inhibit c-myc-dependent cell proliferation, gene transcription and oncogenic transformation .

HY-126979

Mycro2	Others	Cancer
Mycro2 is an inhibitor of c-Myc/Max dimer and DNA binding, with an IC₅₀ value of 23 μM for the inhibition of Myc/Max DNA binding activity. Mycro2 can inhibit c-myc-dependent cell proliferation, gene transcription and oncogenic transformation .

HY-100996

10074-G5

2 Publications Verification

c-Myc Autophagy Cancer

10074-G5 is an inhibitor of c-Myc-Max dimerization with an IC₅₀ of 146 μM.
HY-N12273

Soyasaponin Ae

Acetyl-soyasaponin A5
Others Others

Soyasaponin Ae (Acetyl-soyasaponin A5) can be isolated from the seeds of Glycine max MERRILL .
HY-122683

sAJM589

1 Publications Verification

c-Myc Cancer

sAJM589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC₅₀ of 1.8 μM .
HY-125978

JY-3-094

c-Myc Cancer

JY-3-094 is a Myc inhibitor that inhibits Myc-Max heterodimer formation (IC₅₀: 33 μM) .

10074-G5 2 Publications Verification	c-Myc Autophagy	Cancer
10074-G5 is an inhibitor of *c-Myc-Max* dimerization with an IC₅₀ of 146 μM.

Soyasaponin Ae Acetyl-soyasaponin A5	Others	Others
Soyasaponin Ae (Acetyl-soyasaponin A5) can be isolated from the seeds of Glycine max MERRILL .

sAJM589 1 Publications Verification	c-Myc	Cancer
sAJM589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC₅₀ of 1.8 μM .

JY-3-094	c-Myc	Cancer
JY-3-094 is a Myc inhibitor that inhibits *Myc-Max* heterodimer formation (IC₅₀: 33 μM) .

HY-130736

Janelia Fluor® 549, SE JF549, SE; JF549, NHS	Fluorescent Dye	Others
Janelia Fluor® 549, SE (JF549, SE) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-131021

Janelia Fluor® 549, Azide JF549, Azide	Fluorescent Dye	Others
Janelia Fluor® 549, Azide (JF549, Azide) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-131022

Janelia Fluor® 549 TFA JF549 TFA	Fluorescent Dye	Others
Janelia Fluor® 549 TFA (JF549 TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-131024

Janelia Fluor® 549, Tetrazine JF549, Tetrazine	Fluorescent Dye	Others
Janelia Fluor® 549, Tetrazine (JF549, Tetrazine) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-131023

Janelia Fluor® 549, Maleimide TFA JF549, Maleimide TFA	Fluorescent Dye	Others
Janelia Fluor® 549, Maleimide TFA (JF549, Maleimide TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-150259

MDEG-541	PROTACs c-Myc	Cancer
MDEG-541 is a potent *MYC-MAX* degrader. MDEG-541 is a PROTAC that based on the MYC-MAX dimerization inhibitor 10058-F4 derivative 28RH and Thalidomide (HY-14658). MDEG-541 shows antiproliferative activity. MDEG-541 decreases the expression of GSPT1, MYC, GSPT2, PLK1 protein .

HY-12702

10058-F4 Maximum Cited Publications 34 Publications Verification	c-Myc Autophagy	Cancer
10058-F4 is a c-Myc inhibitor that prevents c-Myc-Max dimerization and transactivation of c-Myc target gene expression.

HY-115839A

Detajmium L-tartrate Detajmium bitartrate; Tachmalcor	Others	Cardiovascular Disease
Detajmium (L-tartrate) is an antiarrhythmic compound. Detajmium has effect on V_max in both dog ventricular muscle and Purkinje fibers was frequency dependent .

HY-N6878

Cauloside D	NO Synthase	Inflammation/Immunology
Cauloside D is a triterpene glycoside isolated from Caulophyllum robustum Max. Cauloside D exerts anti-inflammatory effects through the inhibition of expression of iNOS and proinflammatory cytokines .

HY-N6919

Cauloside C	NO Synthase	Inflammation/Immunology
Cauloside C is a triterpene glycoside isolated from Caulophyllum robustum Max. Cauloside C exerts anti-inflammatory effects through the inhibition of expression of iNOS and proinflammatory cytokines .

HY-N1228

Soyacerebroside I	Others	Others
Soyacerebroside I is a glycosphingolipid, together with Soyacerebroside II, which can be isolated from the seeds of Glycine max Merrill (Leguminosae). Soyacerebroside II shows ionophoretic activity for Ca ²⁺ .

HY-12703

KSI-3716 1 Publications Verification	c-Myc Autophagy	Cancer
KSI-3716 is a potent c-Myc inhibitor that blocks c-MYC/MAX binding to target gene promoters. KSI-3716 is an effective intravesical chemotherapy agent for bladder cancer .

HY-137551

Tiafenacil	Others	Others
Tiafenacil is a new protoporphyrinogen IX oxidase (PPO)-inhibiting herbicide, with IC₅₀ values of 22 to 28 nM for various plant species, including amaranth (Amaranthus tuberculatus), soybean (Glycine max), arabidopsis (Arabidopsis thaliana), and rapeseed (Brassica napus) .

HY-133536

PA Janelia Fluor® 549, SE PA-JF549-NHS	Fluorescent Dye	Others
PA Janelia Fluor 549, SE (PA-JF549-NHS) is a bright photoactivatable fluorophore of JF549,SE (JF549,NHS). JF549,SE (JF549,NHS) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-144878

VPC-70619 1 Publications Verification	c-Myc	Cancer
VPC-70619 is a potent, orally active N-Myc inhibitor. VPC-70619 blocks the N-Myc-Max heterocomplex from binding to DNA E-boxes and demonstrated strong inhibition activity against N-Myc-dependent cell lines as well as high bioavailability in both oral and intraperitoneal administration .

HY-135969

Glycol chitosan 1 Publications Verification	Bacterial	Infection
Glycol chitosan is a chitosan derivative with ethylene glycol branches. Glycol chitosan enhances membrane permeability and leadkage in Glycine max Harosoy 63W cells. Glycol chitosan is biocompatible and biodegradable . Glycol chitosan inhibits E. coli, S. aureus and S. enteritidis growths with MIC values of 4 μg/mL, 32 μg/mL and <0.5 μg/mL, respectively .

HY-124675

MYCMI-6 1 Publications Verification NSC354961	c-Myc Apoptosis	Cancer
MYCMI-6 (NSC354961) is a potent and selective endogenous *MYC:MAX* protein interactions inhibitor. MYCMI-6 blocks MYC-driven transcription and binds selectively to the MYC bHLHZip domain with a K_d of 1.6 μM. MYCMI-6 inhibits tumor cell growth in a MYC-dependent manner (IC₅₀<0.5 μM). MYCMI-6 is not cytotoxic to normal human cells. MYCMI-6 induces apoptosis .

HY-N5072

Desmethylglycitein 4',6,7-Trihydroxyisoflavone	CDK PI3K PKC	Cancer
Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities. Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity . Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1) . Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes .

Cat. No.	Product Name

HY-E0076

96-well Storage Plate
MCE 96-well storage plates are the ideal storage plate for compound library. Conical bottom (V) improves sample recovery and decreases dead volume. MCE 96-well storage plates are completely designed according to ANSI/SBS standards and can be adapted to various testing equipment and automatic workstations.

HY-L109

Protein-protein Interaction Inhibitor Library	576 compounds
Protein protein interactions (PPI) have pivotal roles in life processes. The studies showed that aberrant PPI are associated with various diseases, including cancer, infectious diseases, and neurodegenerative diseases. The classic drug targets are usually enzymes, ion channels, or receptors, the PPI indicate new potential therapeutic targets. Therefore, targeting PPI is a new direction in treating diseases and an essential strategy for the development of new drugs. However, the design of modulators targeting PPI still faces tremendous challenges, such the difficult PPI interfaces for the drug design, lack of ligands reference, lack of guidance rules for the PPI modulators development and high-resolution PPI proteins structures. With the development of high-throughput technology, high-throughput screening is also gradually used for the identification of PPI inhibitors, but the compound library used for conventional target screening is not very effective in screening PPI inhibitors. To improve screening efficiency, MCE carefully selected 576 PPI inhibitors and mainly targeting MDM2-p53, Keap1-Nrf2, PD-1/PD-L1, Myc-Max, etc. MCE Protein-protein Interaction Inhibitor Library is a useful tool for PPI drug discovery and related research.

Protein-protein Interaction Inhibitor Library

576 compounds

Protein protein interactions (PPI) have pivotal roles in life processes. The studies showed that aberrant PPI are associated with various diseases, including cancer, infectious diseases, and neurodegenerative diseases. The classic drug targets are usually enzymes, ion channels, or receptors, the PPI indicate new potential therapeutic targets. Therefore, targeting PPI is a new direction in treating diseases and an essential strategy for the development of new drugs.

However, the design of modulators targeting PPI still faces tremendous challenges, such the difficult PPI interfaces for the drug design, lack of ligands reference, lack of guidance rules for the PPI modulators development and high-resolution PPI proteins structures.

With the development of high-throughput technology, high-throughput screening is also gradually used for the identification of PPI inhibitors, but the compound library used for conventional target screening is not very effective in screening PPI inhibitors. To improve screening efficiency, MCE carefully selected 576 PPI inhibitors and mainly targeting MDM2-p53, Keap1-Nrf2, PD-1/PD-L1, Myc-Max, etc. MCE Protein-protein Interaction Inhibitor Library is a useful tool for PPI drug discovery and related research.

Cat. No.	Product Name	Type

HY-131021

Janelia Fluor® 549, Azide JF549, Azide	Fluorescent Dyes/Probes
Janelia Fluor® 549, Azide (JF549, Azide) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-131022

Janelia Fluor® 549 TFA JF549 TFA	Fluorescent Dyes/Probes
Janelia Fluor® 549 TFA (JF549 TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-130736

Janelia Fluor® 549, SE JF549, SE; JF549, NHS	Fluorescent Dyes/Probes
Janelia Fluor® 549, SE (JF549, SE) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-131024

Janelia Fluor® 549, Tetrazine JF549, Tetrazine	Fluorescent Dyes/Probes
Janelia Fluor® 549, Tetrazine (JF549, Tetrazine) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-131023

Janelia Fluor® 549, Maleimide TFA JF549, Maleimide TFA	Fluorescent Dyes/Probes
Janelia Fluor® 549, Maleimide TFA (JF549, Maleimide TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-133536

PA Janelia Fluor® 549, SE PA-JF549-NHS	Dyes
PA Janelia Fluor 549, SE (PA-JF549-NHS) is a bright photoactivatable fluorophore of JF549,SE (JF549,NHS). JF549,SE (JF549,NHS) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7273

Soyasaponin III	Triterpenes Classification of Application Fields Leguminosae Glycine max (L.) merr Terpenoids Source classification Plants Disease Research Fields Cancer	Apoptosis
Soyasaponin III, a monodesmodic oleanane triterpenoid, is one of the main potentially bioactive saponins found in soy (Glycine max) and related products. Soyasaponin III can induce apoptosis in Hep-G2 cells .

HY-N6878

Cauloside D	Triterpenes Structural Classification Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd. Classification of Application Fields Terpenoids Caulophyllum robustum Maxim. Source classification Plants Berberidaceae Inflammation/Immunology Disease Research Fields Araliaceae	NO Synthase
Cauloside D is a triterpene glycoside isolated from Caulophyllum robustum Max. Cauloside D exerts anti-inflammatory effects through the inhibition of expression of iNOS and proinflammatory cytokines .

HY-N6919

Cauloside C	Triterpenes Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd. Classification of Application Fields Terpenoids Caulophyllum robustum Maxim. Source classification Plants Berberidaceae Inflammation/Immunology Disease Research Fields Araliaceae	NO Synthase
Cauloside C is a triterpene glycoside isolated from Caulophyllum robustum Max. Cauloside C exerts anti-inflammatory effects through the inhibition of expression of iNOS and proinflammatory cytokines .

HY-N6999

Soyasaponin Ac	Triterpenes Classification of Application Fields Leguminosae Glycine max (L.) merr Terpenoids Source classification Metabolic Disease Plants Disease Research Fields	Others
Soyasaponin Ac is a triterpenoid isolated from the seeds of Glycine max.

HY-N12273

Soyasaponin Ae Acetyl-soyasaponin A5	Structural Classification Polysaccharides Leguminosae Glycine max (L.) merr Source classification Plants Saccharides	Others
Soyasaponin Ae (Acetyl-soyasaponin A5) can be isolated from the seeds of Glycine max MERRILL .

HY-N1228

Soyacerebroside I	Structural Classification Natural Products Source classification Aizoaceae Plants	Others
Soyacerebroside I is a glycosphingolipid, together with Soyacerebroside II, which can be isolated from the seeds of Glycine max Merrill (Leguminosae). Soyacerebroside II shows ionophoretic activity for Ca ²⁺ .

HY-N5072

Desmethylglycitein 4',6,7-Trihydroxyisoflavone	Flavonoids Classification of Application Fields Leguminosae Glycine max (L.) merr Source classification Phenols Polyphenols Plants Disease Research Fields Isoflavones Cancer	CDK PI3K PKC
Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities. Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity . Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1) . Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes .

Species:	Human (3)
Tag:	His (4) Avi (1) GST (1)
Source:	HEK293 (1) E. coli Cell-free (1) Sf9 insect cells (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P70388

	MAX Protein, Human (His) rHuMax, His; Protein Max; Class D Basic Helix-Loop-Helix Protein 4; bHLHd4; ; Myc-Associated Factor X; Max; BHLHD4	Human	E. coli
	MAX protein is a transcriptional regulator that forms a complex with MYC to promote activation, or a complex with MAD to cause inhibition, binding to the core sequence 5'-CAC[GA]TG-3'. MAX acts as a repressor protein that recruits chromatin remodeling complexes with H3 "Lys-9" histone methyltransferase activity. MAX Protein, Human (His) is the recombinant human-derived MAX protein, expressed by E. coli , with C-6*His labeled tag. The total length of MAX Protein, Human (His) is 151 a.a., with molecular weight of ~21.0 kDa.

HY-P73832

	MAX Protein, Human (sf9, His-GST) Protein Max; Max; BHLHD4; Myc-associated factor X	Human	Sf9 insect cells
	MAX protein is a transcriptional regulator that forms a complex with MYC to promote activation, or a complex with MAD to cause inhibition, binding to the core sequence 5'-CAC[GA]TG-3'. MAX acts as a repressor protein that recruits chromatin remodeling complexes with H3 "Lys-9" histone methyltransferase activity. MAX Protein, Human (sf9, His-GST) is the recombinant human-derived MAX protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of MAX Protein, Human (sf9, His-GST) is 160 a.a., with molecular weight of ~73 kDa.

HY-P702396

	*Oleosin Protein, Glycine max* (Cell-Free, His)** Oleosin	Others	E. coli Cell-free
	Oleosins are essential for stabilizing liposomes during seed drying, preventing oil coalescence and underscoring their importance in seed physiology. It binds to lipid and phospholipid moieties, suggesting a multifunctional molecular interaction that contributes to liposome integrity. Oleosin Protein, Glycine max (Cell-Free, His) is the recombinant Oleosin protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of Oleosin Protein, Glycine max (Cell-Free, His) is 147 a.a., with molecular weight of 17.3 kDa.

HY-P72414

	CD84/SLAMF5 Protein, Human (Biotinylated, HEK293, His-Avi) SLAM family member 5; Cell surface antigen Max.3; Hly9-beta; Signaling lymphocytic activation molecule 5; CD84	Human	HEK293
	The CD84/SLAMF5 protein, a self-ligand receptor in the SLAM family, modulates diverse immune cell activities through homo- or heterotypic cell-cell interactions. It finely tunes its functions based on the presence or absence of small cytoplasmic adapter proteins, including SH2D1A/SAP and/or SH2D1B/EAT-2. CD84/SLAMF5 mediates NK cell cytotoxicity dependent on SH2D1A and SH2D1B, enhances T-cell proliferative responses, and amplifies IFNG secretion. It is crucial for prolonged T-cell:B-cell contact, germinal center formation, and maintaining B-cell tolerance. In mast cells, it negatively regulates immunoglobulin epsilon receptor signaling, and in macrophages, it positively regulates LPS-induced MAPK phosphorylation and NF-kappaB activation. Additionally, CD84/SLAMF5 positively regulates macroautophagy in dendritic cells and forms homodimers, interacting with CD48 molecules and various signaling proteins, including SH2D1A/SAP, SH2D1B/EAT-2, PTPN6/SHP-1, PTPN11/SHP-2, and INPP5D/SHIP1. CD84/SLAMF5 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD84/SLAMF5 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of CD84/SLAMF5 Protein, Human (Biotinylated, HEK293, His-Avi) is 199 a.a., with molecular weight of 40-50 kDa.

Cat. No.	Product Name	Application	Reactivity

HY-P80777

p38 Antibody MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; Max-interacting protein	WB, IP	Human
p38 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 41 kDa, targeting to p38. It can be used for WB,IP assays with tag free, in the background of Human.

HY-P80776

p38 Antibody (YA696) MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; Max-interacting protein	WB	Human, Mouse, Rat, Monkey
p38 Antibody (YA696) is a non-conjugated and Mouse origined monoclonal antibody about 41 kDa, targeting to p38 (5A1). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat, Monkey.

HY-P82484

Max Dimerization Protein 3 Antibody (YA2229)

bHLHc13; mxd3; Myx
WB, IHC-P, FC Human, Mouse, Rat

HY-P80842

Phospho-p38 (Thr180/Tyr182) Antibody MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; Max-interacting protein	WB	Human, Mouse, Rat
Phospho-p38 (Thr180/Tyr182) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 41 kDa, targeting to Phospho-p38 (Thr180/Tyr182). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P80776A

Phospho-p38 (Thr180+Tyr182) Antibody p38 (phospho T180 + Y182); p-p38 (phospho T180 + Y182); p38 (phospho T180/Y182); CSAID Binding Protein 1; CSAID binding protein; CSAID-binding protein; Csaids binding protein; CSBP 1; CSBP 2; CSBP; CSBP1; CSBP2; CSPB 1; CSPB1; Cytokine suppressive anti inflammatory drug binding protein; Cytokine suppressive anti-inflammatory drug-binding protein; EXIP; MAP kinase 14; MAP kinase MXI2; MAP kinase p38 alpha; MAPK 14; MAPK14; Max interacting protein 2; Max-interacting protein 2; Mitogen Activated Protein Kinase 14; Mitogen activated protein kinase p38 alpha; Mitogen-activated protein kinase 14; Mitogen-activated protein kinase p38 alpha; MK14_HUMAN; Mxi 2; Mxi2; p38 ALPHA; p38; p38 MAP kinase; p38 MAPK; p38 mitogen activated protein kinase; p38ALPHA; p38alpha Exip; PRKM14; PRKM15; RK; SAPK 2A; SAPK2A; Stress Activated Protein Kinase 2A.	WB, IHC-P, Flow-Cyt, ICC, ELISA	Human, Mouse (predicted: Rat, Rabbit, Pig, Chicken, Dog, Horse)

Cat. No.	Product Name		Classification

HY-131021

Janelia Fluor® 549, Azide JF549, Azide		Azide Labeling and Fluorescence Imaging
Janelia Fluor® 549, Azide (JF549, Azide) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-131024

Janelia Fluor® 549, Tetrazine JF549, Tetrazine		Tetrazine Labeling and Fluorescence Imaging
Janelia Fluor® 549, Tetrazine (JF549, Tetrazine) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.


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Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Natural
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Recombinant Proteins

Antibodies

Click Chemistry

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Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

NaturalProducts

Recombinant Proteins

Antibodies

Click Chemistry

Natural
Products