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Results for "

N-cadherin

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

4

Peptides

3

Recombinant Proteins

3

Antibodies

Recombinant Proteins Recommended:
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Tag:
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Cat. No. Compare Product Name Species Source
  • HY-P73302
    N-Cadherin Protein, Human (699a.a, HEK293, His)

    cadherin-2; CD325; CDH2; CDHN; CDw325; NCAD; N-cadherin 1

    		 Human HEK293
    N-Cadherin Protein forms dimers with CDH2 chains, promoting cell-cell adhesion and sorting of cell types. It regulates neural stem cell quiescence by anchoring them to ependymocytes, disrupted by MMP24 cleavage. It also promotes cell-to-cell junctions and neurite branching, and regulates dendritic spine density. N-Cadherin Protein interacts with CDCP1, PCDH8, OBSCN, FGFR4, NCAM1, CDH2, PLCG1, FRS2, SRC, SHC1, GAP43, CTTN, and FBXO45. N-Cadherin Protein, Human (699a.a, HEK293, His) is the recombinant human-derived N-Cadherin protein, expressed by HEK293 , with C-His labeled tag. The total length of N-Cadherin Protein, Human (699a.a, HEK293, His) is 699 a.a., with molecular weight of 75-90 kDa.
  • HY-P73750
    N-Cadherin Protein, Mouse (HEK293)

    cadherin-2; CD325; CDH2; CDHN; CDw325; NCAD; N-cadherin

    		 Mouse HEK293
    N-Cadherin, a calcium-dependent cell adhesion protein, primarily facilitates homotypic cell-cell adhesion through dimerization with a CDH2 chain from neighboring cells. This property contributes to the sorting of heterogeneous cell types. Additionally, N-Cadherin serves as a regulator of neural stem cell quiescence by anchoring these cells to ependymocytes in the adult subependymal zone; MMP24-mediated cleavage of N-Cadherin affects this anchorage, modulating neural stem cell quiescence. In pancreatic beta cells, N-Cadherin plays a crucial role in forming cell-to-cell junctions with neural crest stem cells, promoting the extension of processes by the latter. The protein is essential for proper neurite branching, pre- and postsynaptic organization, and may be involved in neuronal recognition mechanisms. In hippocampal neurons, N-Cadherin potentially regulates dendritic spine density. Functionally, N-Cadherin forms homodimers via its extracellular region and can also form heterodimers with other cadherins in trans, involving a cadherin chain from another cell. Interactions with CDCP1, PCDH8, and OBSCN further underscore the complexity of N-Cadherin's cellular activities, with potential internalization through the TAOK2/p38 MAPK pathway. Moreover, it is identified in a complex containing FGFR4, NCAM1, CDH2, PLCG1, FRS2, SRC, SHC1, GAP43, and CTTN, highlighting its association with diverse cellular components. N-Cadherin Protein, Mouse (HEK293) is the recombinant mouse-derived N-Cadherin protein, expressed by HEK293 , with tag free. The total length of N-Cadherin Protein, Mouse (HEK293) is 699 a.a., with molecular weight of ~91 & 114 kDa, respectively.
  • HY-P75667
    Cadherin-12/CDH12 Protein, Human (HEK293, His)

    CDH12; cadherin 12, type 2 (N-cadherin 2); cadherin-12; Br cadherin; CDHB; Br-cadherin; N-cadherin 2; brain cadherin; brain-cadherin; neuronal cadherin 2; neural type cadherin 2; cadherin, neural type, 2; FLJ34857

    		 Human HEK293
    Cadherin-12/CDH12 is a calcium-dependent cell adhesion protein in the cadherin family known for its preferential homophilic interactions (binding to itself between connecting cells). This interaction is shown to play a crucial role in mediating cell adhesion and may play a key role in sorting heterogeneous cell types. Cadherin-12/CDH12 Protein, Human (HEK293, His) is the recombinant human-derived Cadherin-12/CDH12 protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-12/CDH12 Protein, Human (HEK293, His) is 582 a.a., with molecular weight of 80-85 kDa.

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