NADP

By Targets:	Aldehyde Dehydrogenase (ALDH) (1) Endogenous Metabolite (7) Isocitrate Dehydrogenase (IDH) (2) Lactate Dehydrogenase (1) Microtubule/Tubulin (1) Mitochondrial Metabolism (1) Parasite (1)
By Research Areas:	Cancer (3) Infection (1) Metabolic Disease (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113325

*NADP* 4 Publications Verification	Endogenous Metabolite	Others
NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH). NADPH is the universal electron donor in cellular reductive biosyntheses and detoxification processes, and also plays a key role in oxidative defense system .

HY-F0002

NADP sodium salt 4 Publications Verification Sodium NADP	Endogenous Metabolite	Others
NADP sodium salt is the sodium salt form of NADP (HY-113325). NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH). NADPH is the universal electron donor in cellular reductive biosyntheses and detoxification processes, and also plays a key role in oxidative defense system .

HY-F0002A

NADP disodium salt 4 Publications Verification Disodium NADP	Endogenous Metabolite	Others
NADP disodium salt is the disodium salt form of NADP (HY-113325). NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH). NADPH is the universal electron donor in cellular reductive biosyntheses and detoxification processes, and also plays a key role in oxidative defense system .

HY-113325A

NADP sodium hydrate 4 Publications Verification	Endogenous Metabolite	Others
NADP sodium hydrate, a β-Nicotinamide adenine dinucleotide phosphate sodium salt, is a redox cofactor. NADP sodium hydrate is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH) .

HY-P2947

ALDH Aldehyde dehydrogenase (NAD(P))	Aldehyde Dehydrogenase (ALDH)	Others
ALDH (Aldehyde dehydrogenase (NAD(P))) catalyzes the oxidation of aldehydes into their corresponding carboxylic acids with the concomitant reduction of the cofactor NAD(P) into NAD(P)H, is often used in biochemical studies. The ALDHs are one of many enzyme systems the body utilizes to alleviate aldehyde stress .

HY-P2911

*Glutamate dehydrogenase (NAD(P))* GLDH	Mitochondrial Metabolism	Others
Glutamate dehydrogenase NAD(P) (GLDH) can be found in hepatocytes, renal tissue, brain, muscle, and intestinal cells. Glutamate dehydrogenase NAD(P) is often used in biochemical studies. Glutamate dehydrogenase is a mitochondrial enzyme, it catalyzes the reversible oxidative deamination of glutamate to α-ketoglutarate (α-KG) as part of the urea cycle .

HY-N0352

Tuberostemonine

Parasite Infection

Tuberostemonine, an alkaloid, is an antimalarial agent that targets Plasmodium falciparum ferredoxin-NADP ⁺ reductases (pfFNR) .
HY-118588

Diminutol

Microtubule/Tubulin Others

Diminutol is an inhibitor for NADP-dependent quinone oxidoreductase (NQO1), that is involved in microtubule morphogenesis and cell devision .
HY-150621

AS1134900

Others Cancer

AS1134900 is a highly selective, allosteric and uncompetitive NADP ⁺-dependent malic enzyme 1 (ME1) inhibitor .

Tuberostemonine	Parasite	Infection
Tuberostemonine, an alkaloid, is an antimalarial agent that targets Plasmodium falciparum ferredoxin-NADP ⁺ reductases (pfFNR) .

Diminutol	Microtubule/Tubulin	Others
Diminutol is an inhibitor for NADP-dependent quinone oxidoreductase (NQO1), that is involved in microtubule morphogenesis and cell devision .

AS1134900	Others	Cancer
AS1134900 is a highly selective, allosteric and uncompetitive NADP ⁺-dependent malic enzyme 1 (ME1) inhibitor .

HY-P3186

Glucose dehydrogenase, recombinant Microorganisms	Endogenous Metabolite	Metabolic Disease
Glucose dehydrogenase, recombinant Microorganisms is a oxidoreductase. Glucose dehydrogenase (GDH) catalyzes the oxidation of β-D-glucose to β-D-glucono-1,5-lactone with simultaneous reduction of the cofactor NADP ⁺ to NADPH or, to a lesser extent, NAD ⁺ to NADH. Glucose dehydrogenase (GDH) accepts both NAD ⁺ and NADP ⁺ as cofactors and can be used for the regeneration of NADH and NADPH .

HY-W013046

Phosphoribosyl pyrophosphate pentasodium PRPP pentasodium	Endogenous Metabolite	Others
Phosphoribosyl pyrophosphate (PRPP) pentasodium is an important metabolite required in the biosynthesis of purine and pyrimidine nucleotides, the amino acids histidine and tryptophan, and the cofactors NAD and NADP .

HY-131521

Oxalomalic acid trisodium Oxalomalate trisodium	Isocitrate Dehydrogenase (IDH)	Cancer
Oxalomalic acid (Oxalomalate) trisodium is a aconitase and NADP-dependent isocitrate dehydrogenase inhibitor. Oxalomalic acid trisodium inhibits nitrite production and iNOS protein expression in lipopolysaccharide (HY-D1056)-activated J774 macrophages .

HY-E70014

Glucose dehydrogenase, pseudomonas sp FAD-GDH; Glucose 1-dehydrogenase	Endogenous Metabolite	Others
Glucose 1-dehydrogenase (EC 1.1.5.9), or glucose dehydrogenase (FAD)/Pseudomonas glucose dehydrogenase. Glucose 1-dehydrogenase is an enzyme used as a regeneration cofactor to convert glucose and NAD(P) into NAD(P)H and gluconic acid .

HY-P2897

D-Lactate dehydrogenase, Microorganism D-LDH	Lactate Dehydrogenase	Others
D-Lactate dehydrogenase, Microorganism (D-LDH) is an oxidoreductase that uses NAD ⁺ or NADP ⁺ as an acceptor and acts on the donor CH-OH group, and can catalyze the oxidation of D-lactate to pyruvate. D-Lactate dehydrogenase widely exists in bacteria and fungi, and is often used in biochemical research .

HY-P2993

Isocitrate dehydrogenase, Porcine heart ICDH; IDH	Isocitrate Dehydrogenase (IDH)	Metabolic Disease
Isocitrate dehydrogenase, Porcine heart (ICDH) is a citric acid or tricarboxylic acid cycle enzyme, is often used in biochemical studies. Isocitrate dehydrogenase catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate and reduces NAD(P) ⁺ to NAD(P)H, it plays important roles in cellular metabolism .

HY-W010342

6-Aminonicotinamide 4 Publications Verification	Others	Cancer
6-Aminonicotinamide, a potent antimetabolite of nicotinamide, is competitive NADP ⁺-dependent enzyme glucose-6-phosphate dehydrogenase (G6PD) inhibitor (K_i=0.46 μM). 6-Aminonicotinamide resultis ATP depletion and synergizes with DNA-crosslinking chemotherapy agents, such as Cisplatin, in killing cancer cells .

Cat. No.	Product Name	Type

HY-P2911

*Glutamate dehydrogenase (NAD(P))* GLDH	Biochemical Assay Reagents
Glutamate dehydrogenase NAD(P) (GLDH) can be found in hepatocytes, renal tissue, brain, muscle, and intestinal cells. Glutamate dehydrogenase NAD(P) is often used in biochemical studies. Glutamate dehydrogenase is a mitochondrial enzyme, it catalyzes the reversible oxidative deamination of glutamate to α-ketoglutarate (α-KG) as part of the urea cycle .

HY-154924

Thio-NADP

S-NADP
Biochemical Assay Reagents

Thio-NADP (S-NADP) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Thio-NADP S-NADP	Biochemical Assay Reagents
Thio-NADP (S-NADP) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P2944

*Ferredoxin-NADP* reductase**	Biochemical Assay Reagents
Ferredoxin-NADP reductase is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P2912

*Glutamate dehydrogenase (NADP)*	Biochemical Assay Reagents
Glutamate dehydrogenase (NADP) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P2947

ALDH Aldehyde dehydrogenase (NAD(P))	Biochemical Assay Reagents
ALDH (Aldehyde dehydrogenase (NAD(P))) catalyzes the oxidation of aldehydes into their corresponding carboxylic acids with the concomitant reduction of the cofactor NAD(P) into NAD(P)H, is often used in biochemical studies. The ALDHs are one of many enzyme systems the body utilizes to alleviate aldehyde stress .

HY-P3001

*Malate dehydrogenase oxaloacetate-decarboxylating, NADP+*	Biochemical Assay Reagents
Malate dehydrogenase (oxaloacetate-decarboxylating, NADP+) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P3175

*Phosphogluconate dehydrogenase (NADP, decarboxylating)* 6-Phosphogluconate dehydrogenase	Biochemical Assay Reagents
Phosphogluconate dehydrogenase (NADP, decarboxylating) (6-Phosphogluconate dehydrogenase) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Target	Research Area

HY-P2944

*Ferredoxin-NADP* reductase**	Peptides	Others
Ferredoxin-NADP reductase is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P2912

*Glutamate dehydrogenase (NADP)*	Peptides	Others
Glutamate dehydrogenase (NADP) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P3001

*Malate dehydrogenase oxaloacetate-decarboxylating, NADP+*	Peptides	Others
Malate dehydrogenase (oxaloacetate-decarboxylating, NADP+) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P3175

*Phosphogluconate dehydrogenase (NADP, decarboxylating)* 6-Phosphogluconate dehydrogenase	Peptides	Others
Phosphogluconate dehydrogenase (NADP, decarboxylating) (6-Phosphogluconate dehydrogenase) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113325

*NADP* 4 Publications Verification	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH). NADPH is the universal electron donor in cellular reductive biosyntheses and detoxification processes, and also plays a key role in oxidative defense system .

HY-F0002A

NADP disodium salt 4 Publications Verification Disodium NADP	Structural Classification other families Microorganisms Classification of Application Fields Animals Ketones, Aldehydes, Acids Source classification Other Diseases Plants Disease Research Fields	Endogenous Metabolite
NADP disodium salt is the disodium salt form of NADP (HY-113325). NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH). NADPH is the universal electron donor in cellular reductive biosyntheses and detoxification processes, and also plays a key role in oxidative defense system .

HY-113325A

NADP sodium hydrate 4 Publications Verification	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NADP sodium hydrate, a β-Nicotinamide adenine dinucleotide phosphate sodium salt, is a redox cofactor. NADP sodium hydrate is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH) .

HY-N0352

Tuberostemonine	Infection Alkaloids other families Pyrrole Alkaloids Classification of Application Fields Source classification Plants Disease Research Fields	Parasite
Tuberostemonine, an alkaloid, is an antimalarial agent that targets Plasmodium falciparum ferredoxin-NADP ⁺ reductases (pfFNR) .

HY-W013046

Phosphoribosyl pyrophosphate pentasodium PRPP pentasodium	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Phosphoribosyl pyrophosphate (PRPP) pentasodium is an important metabolite required in the biosynthesis of purine and pyrimidine nucleotides, the amino acids histidine and tryptophan, and the cofactors NAD and NADP .

Species:	Human (4)
Tag:	His (3) Tag Free (1) GST (1)
Source:	HEK293 (2) Sf9 insect cells (1) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P70214

	IDH1 Protein, Human (HEK293, His, Solution) rHuIsocitrate dehydrogenase [NADP] cytoplasmic/IDH1, His; Isocitrate Dehydrogenase [NADP] Cytoplasmic; IDH; Cytosolic NADP-Isocitrate Dehydrogenase; IDP; NADP(+)-Specific ICDH; Oxalosuccinate Decarboxylase; IDH1; PICD	Human	HEK293
	The IDH1 protein catalyzes the oxidative decarboxylation of isocitrate to generate 2-oxoglutarate, which is utilized by enzymes such as phytoacyl-CoA dioxygenase. IDH1 Protein, Human (HEK293, His, Solution) is the recombinant human-derived IDH1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IDH1 Protein, Human (HEK293, His, Solution) is 414 a.a., with molecular weight of ~48 kDa.

HY-P70214A

	IDH1 Protein, Human (HEK293, C-His) rHuIsocitrate dehydrogenase [NADP] cytoplasmic/IDH1, His; Isocitrate Dehydrogenase [NADP] Cytoplasmic; IDH; Cytosolic NADP-Isocitrate Dehydrogenase; IDP; NADP(+)-Specific ICDH; Oxalosuccinate Decarboxylase; IDH1; PICD	Human	HEK293
	The IDH1 protein catalyzes the oxidative decarboxylation of isocitrate to generate 2-oxoglutarate, which is utilized by enzymes such as phytoacyl-CoA dioxygenase. IDH1 Protein, Human (HEK293, C-His) is the recombinant human-derived IDH1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IDH1 Protein, Human (HEK293, C-His) is 414 a.a., with molecular weight of ~48 kDa.

HY-P702131

	COLAER_02088 Protein, Collinsella aerofaciens 7beta-hydroxysteroid dehydrogenase; 7beta-HSDH; NADP-dependent 7beta-hydroxysteroid dehydrogenase	Others	E. coli
	The COLAER_02088 Protein, acting as a 7beta-hydroxysteroid dehydrogenase, transforms 7-oxo-lithocholate into chemopreventive UDCA in the human colon, showcasing its role in bile acid metabolism. This enzyme also exhibits reversible reactions, oxidizing UDCA and utilizing NADPH as its preferred electron acceptor, influencing bile acid dynamics and potential therapeutic applications. COLAER_02088 Protein, Collinsella aerofaciens is the recombinant COLAER_02088 protein, expressed by E. coli , with tag free.

HY-P702132

	COLAER_02088 Protein, Collinsella aerofaciens (GST) 7beta-hydroxysteroid dehydrogenase; 7beta-HSDH; NADP-dependent 7beta-hydroxysteroid dehydrogenase	Others	E. coli
	The COLAER_02088 Protein, acting as a 7beta-hydroxysteroid dehydrogenase, transforms 7-oxo-lithocholate into chemopreventive UDCA in the human colon, showcasing its role in bile acid metabolism. This enzyme also exhibits reversible reactions, oxidizing UDCA and utilizing NADPH as its preferred electron acceptor, influencing bile acid dynamics and potential therapeutic applications. COLAER_02088 Protein, Collinsella aerofaciens (GST) is the recombinant COLAER_02088 protein, expressed by E. coli , with N-GST labeled tag.

HY-P75568

	ALDH3A1 Protein, Human (sf9, His) Aldehyde dehydrogenase, dimeric NADP-preferring; Aldehyde Dehydrogenase 3 member A1; ALDHIII; ALDH3	Human	Sf9 insect cells
	The ALDH3A1 protein is critical for acetaldehyde detoxification in alcohol metabolism, oxidizing medium- and long-chain aldehydes to nontoxic fatty acids. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. ALDH3A1 Protein, Human (sf9, His) is the recombinant human-derived ALDH3A1 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of ALDH3A1 Protein, Human (sf9, His) is 453 a.a., with molecular weight of ~50 kDa.

HY-P71390

	TSTA3 Protein, Human (His) GDP-L-Fucose Synthase; GDP-4-Keto-6-Deoxy-D-Mannose-3; 5-Epimerase-4-Reductase; Protein FX; Red Cell NADP(H)-Binding Protein; Short-Chain Dehydrogenase/Reductase Family 4E Member 1; TSTA3; SDR4E1	Human	E. coli
	The TSTA3 protein plays a key role in catalyzing the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose. The process involves successive epimerase and reductase reactions, ultimately leading to the biosynthesis of GDP-fucose. TSTA3 Protein, Human (His) is the recombinant human-derived TSTA3 protein, expressed by E. coli , with C-6*His labeled tag. The total length of TSTA3 Protein, Human (His) is 321 a.a., with molecular weight of ~40.0 kDa.


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Cat. No.	Product Name	Application	Reactivity

HY-P80590

CBR1 Antibody (YA810) 15 hydroxyprostaglandin dehydrogenase [NADP ]; 15-hydroxyprostaglandin dehydrogenase [NADP ]; Carbonyl reductase [NADPH] 1; CBR 1; CBR1; CBR1_HUMAN; CRN; NADPH dependent carbonyl reductase 1; NADPH-dependent carbonyl reductase 1; Prostaglandin 9 ketoreduc	WB, ICC/IF	Human
CBR1 Antibody (YA810) is a non-conjugated and Mouse origined monoclonal antibody about 30 kDa, targeting to CBR1 (2C9). It can be used for WB,ICC/IF assays with tag free, in the background of Human.

HY-P82255

DPD Antibody (YA2000)

DPYD; Dihydropyrimidine dehydrogenase [NADP(+)]; DHPDHase; DPD; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase
WB, IHC-P, ICC/IF, FC Human

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NADP

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