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Results for "

NAS

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

2

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-103156
    NAS-181 dimesylate
    1 Publications Verification

    		 5-HT Receptor Neurological Disease
    NAS181 is a potent and selective antagonist of rat 5-HT1B receptor, with a Ki of 47 nM. NAS181 shows 13-fold selectivity for r5-HT1B over bovine 5-HT1B receptor (Ki=630 nM). NAS181 increases the 5-HT turnover and the synaptic concentration of 5-HT by inhibiting terminal r5-HT1B autoreceptors .
    <em>NAS</em>-181 dimesylate
  • HY-Y0272
    Saccharin

    		Bacterial Inflammation/Immunology
    Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties .
    Saccharin
  • HY-B1390B
    Saccharin sodium hydrate

    		Bacterial Inflammation/Immunology
    Saccharin sodium hydrate is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium hydrate has bacteriostatic and microbiome-modulating properties .
    Saccharin sodium hydrate
  • HY-135507
    NAS-181

    		5-HT Receptor Neurological Disease
    NAS-181 is a potent and selective rat 5-hydroxytryptamine1B (r5-HT1B) antagonist with an Ki value of 47 nM. NAS-181 increases the 5-HTP accumulation in rat brain regions .
    <em>NAS</em>-181
  • HY-B1390A
    Saccharin sodium

    Saccharin sodium is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium has bacteriostatic and microbiome-modulating properties .
    Saccharin sodium
  • HY-W014395
    Dithiodipropionic acid

    		Reactive Oxygen Species Apoptosis Cancer
    Dithiodipropionic acid can interact with CPUL1 (HY-151802, a TrxR inhibitor) to form nanoaggregates (CPUL1-DA NAs). CPUL1-DA NAs generates more abundant ROS to induce cell apoptosis than that of free CPUL1, and improves antitumor efficacy against HUH7 cancer cells .
    Dithiodipropionic acid
  • HY-Y0272S
    Saccharin-d4

    		Isotope-Labeled Compounds Bacterial Inflammation/Immunology
    Saccharin-d4 is the deuterium labeled Saccharin. Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties[1].
    Saccharin-d4
  • HY-129150
    Ganoderic acid TR

    		Influenza Virus Infection
    Ganoderic acid TR is a broad-spectrum inhibitor against influenza neuraminidases (NAs), particularly H5N1 and H1N1 neuraminidases. The IC50 values of 10.9 and 4.6 μM, respectively .
    Ganoderic acid TR
  • HY-151104
    Neuraminidase-IN-11

    		Influenza Virus Infection
    Neuraminidase-IN-11 (15e) is a potent and selective neuraminidase (NA) inhibitor with the IC50 values of 4.7 nM, 8.46 nM and 1.5 nM against H1N1, H5N1 and H5N8 NAs respectively .
    Neuraminidase-IN-11
  • HY-139991
    Neuraminidase-IN-3

    		Influenza Virus Infection
    Neuraminidase-IN-3 (compound 23d) is a potent influenza neuraminidase (NA) inhibitor with IC50 values of 0.73, 0.26, and 0.63 nM against H1N1, H5N1, and H5N8 NAs, respectively .
    Neuraminidase-IN-3
  • HY-13340
    VU0152100

    VU152100

    		 mAChR Neurological Disease
    VU0152100 (VU152100) is a highly selective mAChR positive allosteric modulator (permeable to the blood-brain barrier). VU0152100 reverses Amphetamine-induced hypermotility in rats and increased levels of extracellular dopamine in nucleus accumbens and caudate-putamen. VU0152100 has good research potential in psychosis and cognitive impairment associated with mental disorders such as schizophrenia .
    VU0152100
  • HY-163393
    Neuraminidase-IN-18

    		Influenza Virus Infection
    Neuraminidase-IN-18 (compound N5) is a novel polyheterocyclic neuraminidase (NA) inhibitor. Neuraminidase-IN-18 shows potency in inhibition of H5N1 NA with an IC50 of 0.14 μM and 0.27 μM against the wild-type H5N1 NA and H5N1-H274Y mutant NA, respectively. Neuraminidase-IN-18 inhibits influenza virus replication by binding to NAs in cell level .
    Neuraminidase-IN-18
  • HY-N2735
    7,3',4'-Trihydroxy-3-benzyl-2H-chromene

    		Influenza Virus Infection Inflammation/Immunology
    7,3',4'-Trihydroxy-3-benzyl-2H-chromene is an reversible noncompetitive neuraminidase (NA) inhibitor. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be isolated from the dried heartwood of Caesalpinia sappan L. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene has potent NAs inhibitory activities with IC50 values of 34.6 µM [H1N1], 39.5 µM [H3N2], and 50.5µM [H9N2], respectively. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be used for the research of influenza virus .
    7,3',4'-Trihydroxy-3-benzyl-2H-chromene

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