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Results for "

NBDs

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (1) Biochemical Assay Reagents (1) Fluorescent Dye (28) HIV (4) Liposome (1) NF-κB (3) P-glycoprotein (1) Phospholipase (1) RAR/RXR (1)
By Research Areas:	Cancer (6) Infection (5) Inflammation/Immunology (3)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-130433

NBD Sphingosine	Fluorescent Dye	Others
NBD Sphingosine (NBD-Sph), a fluorochrome, is a fluorescence-labeled sphingosine. NBD Sphingosine can be uesd for fluorescence assay for sphingosine kinases .

HY-D1580

*C12 NBD* Lactosylceramide**	Fluorescent Dye	Others
C12 NBD Lactosylceramide is a derivative of Lactosylceramide labeled with a C12 NBD fluorescent group. C12 NBD Lactosylceramide can be used to identify Lactosylceramides .

HY-D0133

NBD-X acid	Fluorescent Dye	Others
NBD-X acid is a fluorescent probe for the study of fatty acids and sterols. NBD-X acid provides better yields for labelling biopolymers compared to NBD chloride and fluoride. The fluorescence spectrum of the NBD derivative is highly sensitive to the environment and the fluorescence intensity is significantly reduced in aqueous solutions .

HY-D1621

*3-NBD-C12 Cholesterol*	Fluorescent Dye	Others
C-12 NBD cholesterol is a cholesterol derivative with a hydrophilic fluorophore tag (NBD: Ex=465 nm, Em=535 nm). C-12 NBD cholesterol can be used to study the utilization and metabolism of cholesterol .

HY-D1576

*C6 NBD* L-threo-dihydroceramide**	Fluorescent Dye	Others
C6 NBD L-threo-dihydroceramide is a dihydro-ceramide isomer labeled with a fluorescent group C6 nitrobenzoxadiazole (C6 NBD), can be used to detect ceramide.

HY-145416

G247	Bacterial	Infection
G247 is a specific MsbA inhibitor. G247 acts as a transmembrane domains (TMDs) wedge, symmetrically increasing nucleotide-binding domains (NBDs) separation and preventing conformational transition of MsbA. G247 suppresses ATPase activity by increasing inter-NBD distance .

HY-D1579

*C12 NBD* Globotriaosylceramide**	Fluorescent Dye	Others
C12 NBD galactosylceramide is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide has been used to detect ceramide trihexoside .

HY-139407

*3-C12-NBD-cholesterol* 3-Dodecanoyl-NBD-cholesterol	Fluorescent Dye	Others
3-C12-NBD-cholesterol is a fluorescent cholesterol analog that can be used for measuring membrane and intracellular trafficking dynamics .

HY-139989

NBD-14270	HIV	Infection
NBD-14270, a pyridine analogue, is a potent HIV-1 entry antagonist with an IC₅₀ of 180 nM against 50 HIV-1 Env-pseudotyped viruses. NBD-14270 binds to HIV-1 gp120 and shows potent antiviral activity. NBD-14270 shows low cytotoxicity (CC₅₀>100 μM) .

HY-141577

*C12-NBD* Sphinganine**	Biochemical Assay Reagents	Others
C12-NBD Sphinganine is a fluorescent ceramidase substrate. C12-NBD Sphinganine can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources .

HY-76649

NBD-557

1 Publications Verification

HIV Infection

NBD-557 is a potentially HIV-1 inhibitor.

NBD-557 1 Publications Verification	HIV	Infection
NBD-557 is a potentially HIV-1 inhibitor.

HY-147738

SQM-NBD	Fluorescent Dye	Others
SQM-NBD is a potent and selectiveAIE fluorescent probe. SQM-NBD exhibits excellent sensitivity to Cys and Hcy with the LOD of 54 nM and 72 nM, respectively.SQM-NBD has good cell permeability and low cytotoxicity. SQM-NBD has the potential for Cys/Hcy identification under physiological and pathological conditions .

HY-76648

NBD-556	HIV	Infection
NBD-556, a CD4 mimetic, is a potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction. NBD-556 shows potent cell fusion and virus-cell fusion inhibitory activity at low micromolar levels .

HY-D1671

TRITC-DHPE	Fluorescent Dye	Others
TRITC-DHPE is a rhodamine-labeled glycerophosphate ethanolamine lipid, with head groups marked with bright red fluorescent TRITC dye (λEx/λEm=514/580 nm). TRITC-DHPE can be used for membrane fusion assay to trace lipid processing in intracellular phagocytosis. TRITC-DHPE can serves as an energy transfer receptor for NBD, BODIPY and fluorescein lipid probes .

HY-D1574

*C6 NBD* Sphingomyelin**	Fluorescent Dye	Others
C6 NBD Sphingomyelin is a fluorescent short-chain analogue of Sphingomyelin (HY-113498). Chlamydia trachomatis acquires C6 NBD Sphingomyelin endogenously synthesizes from C6-NBD-ceramide and transportes to the chlamydial inclusion. C6 NBD Sphingomyelin can incorporate into the plasma membrane .

HY-145493

*C12 NBD* Galactosylceramide**	Fluorescent Dye	Others
C12 NBD galactosylceramide, fluorescent dye, is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide can be used for the research of imaging .

HY-139985

NBD-14189	HIV	Infection
NBD-14189 is a potent HIV-1 entry antagonist with an IC₅₀ of 89 nM against the HIV-1_HXB2 pseudovirus. NBD-14189 binds to HIV-1 gp120 and shows potent antiviral activity (EC₅₀<200 nM) .

HY-141576

C6-NBD Sphinganine

Fluorescent Dye Others

C6-NBD Sphinganine is a sphinganine analog and can be used as fluorescent dye for labeling fatty acid .
HY-P10081

CTP-NBD

NF-κB Inflammation/Immunology

CTP-NBD is a cell permeable specific NFκB peptide inhibitor. CTP-NBD could be used in colitis study

*C6-NBD* Sphinganine**	Fluorescent Dye	Others
C6-NBD Sphinganine is a sphinganine analog and can be used as fluorescent dye for labeling fatty acid .

CTP-NBD	NF-κB	Inflammation/Immunology
CTP-NBD is a cell permeable specific NFκB peptide inhibitor. CTP-NBD could be used in colitis study

HY-119791

NBD-amine	Others	Others
NBD-amine is a fluorogenic amine. NBD-amine displays the property of fluorescing weakly in water and strongly in organic solvents, membranes or hydrophobic environments .

HY-D1749

*C6 NBD* L-threo-ceramide**	Fluorescent Dye	Others
C6 NBD L-threo-ceramide is a cell-permeable analog of ceramides that is tagged with a fluorescent group C6 nitrobenzoxadiazole (C6 NBD). It is rapidly transferred between liposomes, labels the Golgi apparatus, and is metabolized to C6 NBD sphingomyelin in BHK cells and V79 fibroblasts.

HY-133739

NBD-125

RAR/RXR Cancer

NBD-125 (B-12), a berberine analogue, is an RXRα activator, with an IC₅₀ of 31.10 μM in KM12C cell .

NBD-125	RAR/RXR	Cancer
NBD-125 (B-12), a berberine analogue, is an RXRα activator, with an IC₅₀ of 31.10 μM in KM12C cell .

HY-D1584

*C12 NBD* Sphingomyelin**	Phospholipase	Others
C12 NBD sphingomyelin is an active derivative of sphingomyelin (HY-113498) that is tagged with fluorescent C12 nitrobenzoxadiazole (C12 NBD). C12 NBD sphingomyelin can be used as a sphingomyelinase substrate for studying the metabolism and transport of sphingomyelins (Ex=470 nm, Em=525 nm) .

HY-D1575

*C6 NBD* Galactosylceramide**	Fluorescent Dye	Others
C6 NBD galactosylceramide is an active derivative of galactosylceramide that is tagged with fluorescent C6 nitrobenzoxadiazole (C6 NBD). C6 NBD galactosylceramide can be used as a substrate for neutral β-glycosylceramidase (GCase) to study intracellular localization and metabolism of galactosylceramide (Ex=nm, Em=525) .

HY-P1847

*IKKγ NBD* Inhibitory Peptide**	NF-κB	Cancer
IKKγ NBD Inhibitory Peptide is a highly specific inhibitor NF-κB inhibitor. IKKγ NBD Inhibitory Peptide acts by disrupting the interaction between IKKγ/NEMO-binding domain (NBD) with IKKα and IKKβ, thus blocking TNF-α-induced NF-kB activation. IKKγ NBD Inhibitory Peptide could significantly suppresses inflammation and ameliorate the cerebral ischemia-induced neurological deficits .

HY-147178

*C-6 NBD-dihydro-Ceramide*	Others	Others
C-6 NBD-dihydro-Ceramide is a membrane-permeable ceramides. C-6 NBD-dihydro-Ceramide is a biologically active fluorescent analog of short chain .

HY-P1847A

*IKKγ NBD* Inhibitory Peptide TFA**	NF-κB	Inflammation/Immunology
IKKγ NBD Inhibitory Peptide TFA is a highly specific inhibitor NF-κB inhibitor. IKKγ NBD Inhibitory Peptide TFA acts by disrupting the interaction between IKKγ/NEMO-binding domain (NBD) with IKKα and IKKβ, thus blocking TNF-α-induced NF-kB activation. IKKγ NBD Inhibitory Peptide TFA could significantly suppresses inflammation and ameliorate the cerebral ischemia-induced neurological deficits .

HY-D1683

NBD-PE	Fluorescent Dye	Others
NBD-PE is an effective lipid fluorescent probe (Excitation/Emission: 465/535 nm; Color: Green). NBD-PE offers a wide array of applications in membrane and cell biology .

HY-D1577

*C6 NBD* Lactosylceramide**	Fluorescent Dye	Cancer
C6 NBD Lactosylceramide is a derivative of lactosylceramides, and can be used in lactosylceramide synthase assay as a fluorescent acceptor substrate. C6 NBD Lactosylceramide can also be used in cancer research .

HY-D1521

N-(NBD-Aminolauroyl)safingol

Fluorescent Dye Others

N-(NBD-Aminolauroyl)safingol is a fluorescent group.
HY-D1770

NBD Dihexadecylamine

Fluorescent Dye Others

NBD Dihexadecylamine is a fluorescent probe used for labeling phospholipids.
HY-400541

NBD dodecanoic acid N-succinimidyl ester

Others Others

NBD dodecanoic acid N-succinimidyl ester is a fluorescent dye .

*N-(NBD-Aminolauroyl)safingol*	Fluorescent Dye	Others
N-(NBD-Aminolauroyl)safingol is a fluorescent group.

NBD Dihexadecylamine	Fluorescent Dye	Others
NBD Dihexadecylamine is a fluorescent probe used for labeling phospholipids.

NBD dodecanoic acid N-succinimidyl ester	Others	Others
NBD dodecanoic acid N-succinimidyl ester is a fluorescent dye .

HY-W356117

*C6 NBD* Glucosylceramide**	Fluorescent Dye	Others
C6 NBD Glucosylceramide is a glucosylceramide fluorescent derivative (Ex=466 nm, Em=535 nm). C6 NBD Glucosylceramide can be used to study the metabolism and internalization of glucosylceramide and also for the determination of glucosyl ceramide synthase activity .

HY-D0785

NBD-F 4-Fluoro-7-nitrobenzofurazan	Fluorescent Dye	Others
NBD-F (4-Fluoro-7-nitrobenzofurazan) is a pro-fluorescent reagent which is developed for amino acid analysis. NBD-F reacts with primary or secondary amines to produce a fluorescent product and used for analysis of amino acids and low molecular weight amines .

HY-W356116

*C6 NBD* Ceramide** Nbd-ceramide	Fluorescent Dye	Others
C6 NBD Ceramide is a Golgi apparatus fluorescent probe with cell membrane permeability. C6 NBD Ceramide can be used for fast and convenient green fluorescent labeling of Golgi in living and fixed cells, and can be used to observe changes in Golgi morphology in living cells (Ex=466 nm, Em=536 nm). C6-NBD-ceramide is metabolized to fluorescent sphingomyelin and glucosylceramide, can be used for the study of sphingolipid transport and metabolic mechanism .

HY-134566

NBD-X, SE

Fluorescent Dye Others

NBD-X, SE, the acceptor fluorophore, can be used to create environment sensitive bioconjugates .

NBD-X, SE	Fluorescent Dye	Others
NBD-X, SE, the acceptor fluorophore, can be used to create environment sensitive bioconjugates .

HY-D0042

NBD-Cl 1 Publications Verification NBD chloride	Fluorescent Dye	Others
NBD-Cl is a nonfluorescent reagent which becomes highly fluorescent after reaction with thiol or amino groups .

HY-D1582

C12 NBD Phytoceramide

Fluorescent Dye Others

C12 NBD Phytoceramide, a ceramide analogue, is a fluorescent substrate, can be used to detect ceramidase activity .
HY-141575

C12-NBD-ceramide

Fluorescent Dye Others

C12-NBD-ceramide is a fluorescent analogue of ceramide, it can be used as a substrate in ceramidase assays .
HY-D1573

C6 NBD Phytoceramide

Fluorescent Dye Others

C6 NBD Phytoceramide is a fluorescently labeled short-chain ceramide analog that can be recognized by mammalian GlcCer synthase (GCS) .
HY-157316

TZ-NBD

Fluorescent Dye Others

TZ-NBD is a dual-channel sensitive fluorescence probe that exhibits fast response, and excellent selectivity to detect biothiols in vitro and in vivo .

*C12 NBD* Phytoceramide**	Fluorescent Dye	Others
C12 NBD Phytoceramide, a ceramide analogue, is a fluorescent substrate, can be used to detect ceramidase activity .

*C12-NBD-ceramide*	Fluorescent Dye	Others
C12-NBD-ceramide is a fluorescent analogue of ceramide, it can be used as a substrate in ceramidase assays .

*C6 NBD* Phytoceramide**	Fluorescent Dye	Others
C6 NBD Phytoceramide is a fluorescently labeled short-chain ceramide analog that can be recognized by mammalian GlcCer synthase (GCS) .

TZ-NBD	Fluorescent Dye	Others
TZ-NBD is a dual-channel sensitive fluorescence probe that exhibits fast response, and excellent selectivity to detect biothiols in vitro and in vivo .

HY-131682

*3-C6-NBD-cholesterol* 3-Hexanoyl-NBD-cholesterol	Others Fluorescent Dye	Others
3-C6-NBD-cholesterol is a fluorescent analog of Chol that can be used to measure the kinetics of membrane and intracellular trafficking .

HY-143702

Fluorescent DOTAP NBD-DOTAP	Liposome	Inflammation/Immunology Cancer
Fluorescent DOTAP, a cationic lipid, can be used for the research of nucleic acid and protein delivery . Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm).

HY-149277

FM04	P-glycoprotein	Cancer
FM04 is a potent P-glycoprotein (P-gp) inhibitor (EC₅₀=83 nM). FM04 inhibits P-gp in 2 mechanism: (1)FM04 binds to Q1193, followed by interacting with the functionally critical residues H1195 and T1226; or (2)FM04 binds to I1115 (a functionally critical residue itself), disrupting the R262-Q1081-Q1118 interaction pocket and uncoupling ICL2-NBD2 interaction and thereby inhibiting P-gp .

Cat. No.	Product Name	Type

HY-130433

NBD Sphingosine

Dyes

NBD Sphingosine (NBD-Sph), a fluorochrome, is a fluorescence-labeled sphingosine. NBD Sphingosine can be uesd for fluorescence assay for sphingosine kinases .

NBD Sphingosine	Dyes
NBD Sphingosine (NBD-Sph), a fluorochrome, is a fluorescence-labeled sphingosine. NBD Sphingosine can be uesd for fluorescence assay for sphingosine kinases .

HY-D1580

*C12 NBD* Lactosylceramide**	Fluorescent Dyes/Probes
C12 NBD Lactosylceramide is a derivative of Lactosylceramide labeled with a C12 NBD fluorescent group. C12 NBD Lactosylceramide can be used to identify Lactosylceramides .

HY-D0133

NBD-X acid	Fluorescent Dyes/Probes
NBD-X acid is a fluorescent probe for the study of fatty acids and sterols. NBD-X acid provides better yields for labelling biopolymers compared to NBD chloride and fluoride. The fluorescence spectrum of the NBD derivative is highly sensitive to the environment and the fluorescence intensity is significantly reduced in aqueous solutions .

HY-D1621

*3-NBD-C12 Cholesterol*	Fluorescent Dyes/Probes
C-12 NBD cholesterol is a cholesterol derivative with a hydrophilic fluorophore tag (NBD: Ex=465 nm, Em=535 nm). C-12 NBD cholesterol can be used to study the utilization and metabolism of cholesterol .

HY-D1579

*C12 NBD* Globotriaosylceramide**	Fluorescent Dyes/Probes
C12 NBD galactosylceramide is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide has been used to detect ceramide trihexoside .

HY-141577

*C12-NBD* Sphinganine**	Dyes
C12-NBD Sphinganine is a fluorescent ceramidase substrate. C12-NBD Sphinganine can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources .

HY-D1671

TRITC-DHPE	Fluorescent Dyes/Probes
TRITC-DHPE is a rhodamine-labeled glycerophosphate ethanolamine lipid, with head groups marked with bright red fluorescent TRITC dye (λEx/λEm=514/580 nm). TRITC-DHPE can be used for membrane fusion assay to trace lipid processing in intracellular phagocytosis. TRITC-DHPE can serves as an energy transfer receptor for NBD, BODIPY and fluorescein lipid probes .

HY-D1574

*C6 NBD* Sphingomyelin**	Fluorescent Dyes/Probes
C6 NBD Sphingomyelin is a fluorescent short-chain analogue of Sphingomyelin (HY-113498). Chlamydia trachomatis acquires C6 NBD Sphingomyelin endogenously synthesizes from C6-NBD-ceramide and transportes to the chlamydial inclusion. C6 NBD Sphingomyelin can incorporate into the plasma membrane .

HY-129109

NBD-Pen

Fluorescent Dyes/Probes

NBD-Pen is a fluorescence probe. NBD-Pen can be used for the research of detection of lipid-derived radicals .

HY-145493

*C12 NBD* Galactosylceramide**	Fluorescent Dyes/Probes
C12 NBD galactosylceramide, fluorescent dye, is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide can be used for the research of imaging .

HY-141576

C6-NBD Sphinganine

Fluorescent Dyes/Probes

C6-NBD Sphinganine is a sphinganine analog and can be used as fluorescent dye for labeling fatty acid .

HY-D1749

*C6 NBD* L-threo-ceramide**	Fluorescent Dyes/Probes
C6 NBD L-threo-ceramide is a cell-permeable analog of ceramides that is tagged with a fluorescent group C6 nitrobenzoxadiazole (C6 NBD). It is rapidly transferred between liposomes, labels the Golgi apparatus, and is metabolized to C6 NBD sphingomyelin in BHK cells and V79 fibroblasts.

HY-D1584

*C12 NBD* Sphingomyelin**	Fluorescent Dyes/Probes
C12 NBD sphingomyelin is an active derivative of sphingomyelin (HY-113498) that is tagged with fluorescent C12 nitrobenzoxadiazole (C12 NBD). C12 NBD sphingomyelin can be used as a sphingomyelinase substrate for studying the metabolism and transport of sphingomyelins (Ex=470 nm, Em=525 nm) .

HY-D1575

*C6 NBD* Galactosylceramide**	Dyes
C6 NBD galactosylceramide is an active derivative of galactosylceramide that is tagged with fluorescent C6 nitrobenzoxadiazole (C6 NBD). C6 NBD galactosylceramide can be used as a substrate for neutral β-glycosylceramidase (GCase) to study intracellular localization and metabolism of galactosylceramide (Ex=nm, Em=525) .

HY-D1683

NBD-PE	Fluorescent Dyes/Probes
NBD-PE is an effective lipid fluorescent probe (Excitation/Emission: 465/535 nm; Color: Green). NBD-PE offers a wide array of applications in membrane and cell biology .

HY-D1577

*C6 NBD* Lactosylceramide**	Fluorescent Dyes/Probes
C6 NBD Lactosylceramide is a derivative of lactosylceramides, and can be used in lactosylceramide synthase assay as a fluorescent acceptor substrate. C6 NBD Lactosylceramide can also be used in cancer research .

HY-D1770

NBD Dihexadecylamine

Fluorescent Dyes/Probes

NBD Dihexadecylamine is a fluorescent probe used for labeling phospholipids.

HY-W356117

*C6 NBD* Glucosylceramide**	Fluorescent Dyes/Probes
C6 NBD Glucosylceramide is a glucosylceramide fluorescent derivative (Ex=466 nm, Em=535 nm). C6 NBD Glucosylceramide can be used to study the metabolism and internalization of glucosylceramide and also for the determination of glucosyl ceramide synthase activity .

HY-D0785

NBD-F 4-Fluoro-7-nitrobenzofurazan	Fluorescent Dyes/Probes
NBD-F (4-Fluoro-7-nitrobenzofurazan) is a pro-fluorescent reagent which is developed for amino acid analysis. NBD-F reacts with primary or secondary amines to produce a fluorescent product and used for analysis of amino acids and low molecular weight amines .

HY-W356116

C6 NBD Ceramide

Nbd-ceramide

Dyes

C6 NBD Ceramide is a Golgi apparatus fluorescent probe with cell membrane permeability. C6 NBD Ceramide can be used for fast and convenient green fluorescent labeling of Golgi in living and fixed cells, and can be used to observe changes in Golgi morphology in living cells (Ex=466 nm, Em=536 nm). C6-NBD-ceramide is metabolized to fluorescent sphingomyelin and glucosylceramide, can be used for the study of sphingolipid transport and metabolic mechanism .

HY-134566

NBD-X, SE

Fluorescent Dyes/Probes

NBD-X, SE, the acceptor fluorophore, can be used to create environment sensitive bioconjugates .
HY-D0042

NBD-Cl

1 Publications Verification

NBD chloride
Dyes

NBD-Cl is a nonfluorescent reagent which becomes highly fluorescent after reaction with thiol or amino groups .
HY-D1582

C12 NBD Phytoceramide

Chromogenic Substrates

C12 NBD Phytoceramide, a ceramide analogue, is a fluorescent substrate, can be used to detect ceramidase activity .
HY-141575

C12-NBD-ceramide

Fluorescent Dyes/Probes

C12-NBD-ceramide is a fluorescent analogue of ceramide, it can be used as a substrate in ceramidase assays .
HY-D1573

C6 NBD Phytoceramide

Fluorescent Dyes/Probes

C6 NBD Phytoceramide is a fluorescently labeled short-chain ceramide analog that can be recognized by mammalian GlcCer synthase (GCS) .

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