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Results for "

NEDD8

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

1

Peptides

6

Recombinant Proteins

4

Antibodies

Recombinant Proteins Recommended:
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Cat. No. Compare Product Name Species Source
  • HY-P70843
    NEDD8 Protein, Human

    Neural precursor cell expressed developmentally down-regulated protein 8; NEDD8; NEDDylin; Ubiquitin-like protein NEDD8

    		 Human E. coli
    NEDD8 is an important ubiquitin-like protein that plays a key role in cell cycle regulation and embryogenesis by binding to specific proteins such as cullin and p53/TP53. Its binding to cullin is critical for recruiting E2 enzymes to the cullin-RING-based E3 ubiquitin-protein ligase complex, thereby enabling degradation of regulatory proteins. NEDD8 Protein, Human is the recombinant human-derived NEDD8 protein, expressed by E. coli , with tag free. The total length of NEDD8 Protein, Human is 76 a.a., with molecular weight of ~9.0 kDa.
  • HY-P71406
    UBE2M Protein, Human

    NEDD8-conjugating enzyme Ubc12; NEDD8 carrier protein; NEDD8 protein ligase; Ubiquitin-conjugating enzyme E2 M; UBC12; UBE2M;

    		Human E. coli
    UBE2M Protein is a crucial mediator in the ubiquitin-like protein NEDD8 conjugation pathway. It accepts NEDD8 from the UBA3-NAE1 E1 complex, covalently attaching it to target proteins like CUL1, CUL2, CUL3, and CUL4, particularly interacting with the E3 ubiquitin ligase RBX1. This specificity in neddylating specific targets suggests a pivotal role in regulating cellular processes, notably contributing to cell proliferation. UBE2M Protein, Human is the recombinant human-derived UBE2M protein, expressed by E. coli, with tag free. The total length of UBE2M Protein, Human is 183 a.a., with molecular weight of ~25.0 kDa.
  • HY-P79452
    UBE2N/Ubc13 Protein, Human (sf9, His, Strep)

    NEDD8-conjugating enzyme UBE2F; UBE2F; NEDD8 carrier protein UBE2F; NEDD8 protein ligase UBE2F; NEDD8-conjugating enzyme 2; RING-type E3 NEDD8 transferase UBE2F; Ubiquitin-conjugating enzyme E2 F; NCE2

    		Human Sf9 insect cells
    The UBE2F protein accepts NEDD8 from the UBA3-NAE1 E1 complex and covalently links it to various target proteins in the ubiquitin-like NEDD8 conjugation pathway. The RBX2-UBE2F complex specifically interacts with the E3 ubiquitin ligase RBX2, but not RBX1, for the neddylation of specific targets, especially CUL5. UBE2N/Ubc13 Protein, Human (sf9, His, Strep) is the recombinant Rhesus Macaque, cynomolgus-derived UBE2N/Ubc13 protein, expressed by Sf9 insect cells , with N-8*His, N-Strep labeled tag. The total length of UBE2N/Ubc13 Protein, Human (sf9, His, Strep) is 151 a.a., .
  • HY-P76688
    UBE2F Protein, Human (His)

    NEDD8-conjugating enzyme UBE2F; NCE2

    		 Human E. coli
    UBE2F Protein, in the ubiquitin-like NEDD8 conjugation pathway, accepts NEDD8 from the UBA3-NAE1 E1 complex and covalently attaches it to various target proteins. Interacting specifically with the E3 ubiquitin ligase RBX2, not RBX1, the RBX2-UBE2F complex is specialized in neddylating specific targets, notably CUL5. This specific interaction and neddylating activity underscore UBE2F's role in regulating cellular processes through targeted ubiquitination of key substrates. UBE2F Protein, Human (His) is the recombinant human-derived UBE2F protein, expressed by E. coli, with N-His labeled tag. The total length of UBE2F Protein, Human (His) is 185 a.a., with molecular weight of ~25 kDa.
  • HY-P76688A
    UBE2F Protein, Human (His, Solution)

    NEDD8-conjugating enzyme UBE2F; NCE2

    		 Human E. coli
  • HY-P71290
    SENP8 Protein, Human (His)

    Sentrin-Specific Protease 8; DeNEDDylase-1; NEDD8-Specific Protease 1; Protease Cysteine 2; Sentrin/SUMO-Specific Protease SENP8; SENP8; DEN1; NEDP1; PRSC2

    		 Human E. coli
    SENP8 protein, a pivotal protease in the NEDD8 pathway, plays a dual role in catalyzing the processing of full-length NEDD8 into its mature form and facilitating the deconjugation of NEDD8 from specific target proteins, including cullins and p53. SENP8's dual functionality underscores its crucial role in regulating NEDD8 modification, impacting various cellular pathways and functions. SENP8 Protein, Human (His) is the recombinant human-derived SENP8 protein, expressed by E. coli , with N-6*His labeled tag. The total length of SENP8 Protein, Human (His) is 212 a.a., with molecular weight of ~22.0 kDa.

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