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Results for "

NSCs

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Adenosine Kinase (1) Akt (3) Amino Acid Derivatives (1) Aminopeptidase (1) AMPK (3) Antibiotic (11) Antifolate (2) Apoptosis (55) Aryl Hydrocarbon Receptor (1) Atg4 (1) Autophagy (18) Bacterial (15) Bcl-2 Family (2) Bcr-Abl (2) Biochemical Assay Reagents (2) c-Myc (1) Calcium Channel (5) Carbonic Anhydrase (1) CCR (1) CDK (3) Checkpoint Kinase (Chk) (2) Chloride Channel (3) COX (13) Cuproptosis (1) Cytochrome P450 (2) Deubiquitinase (1) Dipeptidyl Peptidase (1) DNA Alkylator/Crosslinker (9) DNA Methyltransferase (3) DNA Stain (2) DNA/RNA Synthesis (18) Drug Metabolite (2) E1/E2/E3 Enzyme (4) EGFR (5) Endogenous Metabolite (18) Epigenetic Reader Domain (2) ERK (1) Ferroptosis (5) FGFR (1) Fluorescent Dye (1) Fungal (1) Gli (1) GLUT (2) GSK-3 (1) HCV (1) HDAC (1) HIF/HIF Prolyl-Hydroxylase (2) Histamine Receptor (3) Histone Acetyltransferase (4) Histone Demethylase (2) Histone Methyltransferase (2) HIV (7) HSP (1) HSV (2) Interleukin Related (2) IRE1 (1) Isotope-Labeled Compounds (33) JAK (2) JNK (1) Keap1-Nrf2 (1) Kinesin (1) LPL Receptor (1) MDM-2/p53 (8) Microtubule/Tubulin (2) MMP (2) mTOR (2) nAChR (2) Necroptosis (1) NF-κB (4) NO Synthase (1) Notch (2) Nucleoside Antimetabolite/Analog (11) Orthopoxvirus (3) P-glycoprotein (2) p38 MAPK (1) Parasite (9) PARP (1) PD-1/PD-L1 (1) PERK (1) Phosphatase (6) PI3K (1) PKC (4) Potassium Channel (4) PROTACs (1) Proteasome (1) Ras (3) Reactive Oxygen Species (3) RET (1) Reverse Transcriptase (1) SARS-CoV (2) Ser/Thr Protease (2) SGLT (2) SHP2 (2) Src (1) STAT (4) Stearoyl-CoA Desaturase (SCD) (1) Syk (1) TET Protein (2) Topoisomerase (8) VDAC (1) VEGFR (1) Virus Protease (1) Wnt (3) β-catenin (1)
By Research Areas:	Cancer (182) Cardiovascular Disease (5) Endocrinology (2) Infection (31) Inflammation/Immunology (37) Metabolic Disease (12) Neurological Disease (15)

By Targets:

5-HT Receptor (1)

Adenosine Kinase (1)

Akt (3)

Amino Acid Derivatives (1)

Aminopeptidase (1)

AMPK (3)

Antibiotic (11)

Antifolate (2)

Apoptosis (55)

Aryl Hydrocarbon Receptor (1)

Atg4 (1)

Autophagy (18)

Bacterial (15)

Bcl-2 Family (2)

Bcr-Abl (2)

Biochemical Assay Reagents (2)

c-Myc (1)

Calcium Channel (5)

Carbonic Anhydrase (1)

CCR (1)

CDK (3)

Checkpoint Kinase (Chk) (2)

Chloride Channel (3)

COX (13)

Cuproptosis (1)

Cytochrome P450 (2)

Deubiquitinase (1)

Dipeptidyl Peptidase (1)

DNA Alkylator/Crosslinker (9)

DNA Methyltransferase (3)

DNA Stain (2)

DNA/RNA Synthesis (18)

Drug Metabolite (2)

E1/E2/E3 Enzyme (4)

EGFR (5)

Endogenous Metabolite (18)

Epigenetic Reader Domain (2)

ERK (1)

Ferroptosis (5)

FGFR (1)

Fluorescent Dye (1)

Fungal (1)

Gli (1)

GLUT (2)

GSK-3 (1)

HCV (1)

HDAC (1)

HIF/HIF Prolyl-Hydroxylase (2)

Histamine Receptor (3)

Histone Acetyltransferase (4)

Histone Demethylase (2)

Histone Methyltransferase (2)

HIV (7)

HSP (1)

HSV (2)

Interleukin Related (2)

IRE1 (1)

Isotope-Labeled Compounds (33)

JAK (2)

JNK (1)

Keap1-Nrf2 (1)

Kinesin (1)

LPL Receptor (1)

MDM-2/p53 (8)

Microtubule/Tubulin (2)

MMP (2)

mTOR (2)

nAChR (2)

Necroptosis (1)

NF-κB (4)

NO Synthase (1)

Notch (2)

Nucleoside Antimetabolite/Analog (11)

Orthopoxvirus (3)

P-glycoprotein (2)

p38 MAPK (1)

Parasite (9)

PARP (1)

PD-1/PD-L1 (1)

PERK (1)

Phosphatase (6)

PI3K (1)

PKC (4)

Potassium Channel (4)

PROTACs (1)

Proteasome (1)

Ras (3)

Reactive Oxygen Species (3)

RET (1)

Reverse Transcriptase (1)

SARS-CoV (2)

Ser/Thr Protease (2)

SGLT (2)

SHP2 (2)

Src (1)

STAT (4)

Stearoyl-CoA Desaturase (SCD) (1)

Syk (1)

TET Protein (2)

Topoisomerase (8)

VDAC (1)

VEGFR (1)

Virus Protease (1)

Wnt (3)

β-catenin (1)

By Research Areas:

Cancer (182)

Cardiovascular Disease (5)

Endocrinology (2)

Infection (31)

Inflammation/Immunology (37)

Metabolic Disease (12)

Neurological Disease (15)

289

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-120782

Yhhu-3792	Notch	Neurological Disease
Yhhu-3792 enhances the self-renewal capability of neural stem cells (NSCs). Yhhu-3792 activates Notch signaling pathway and promotes the expression of Hes3 and Hes5. Yhhu-3792 expands the NSCs pool and promotes endogenous neurogenesis in the hippocampal dentate gyrus (DG) in mouse. Yhhu-3792 increases the spatial and episodic memory abilities of mice. Yhhu-3792 has the potential for the research of impairment of learning and memory associated DG dysfunction .

HY-15036

Diclofenac 10+ Cited Publications	COX Apoptosis	Inflammation/Immunology Cancer
Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

HY-15038

Diclofenac potassium 10+ Cited Publications	COX Apoptosis	Inflammation/Immunology
Diclofenac potassium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac potassium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

HY-15037

Diclofenac Sodium 10+ Cited Publications GP 45840	COX Apoptosis	Inflammation/Immunology Cancer
Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

HY-120782A

Yhhu-3792 hydrochloride	Notch	Neurological Disease
Yhhu-3792 hydrochloride enhances the self-renewal capability of neural stem cells (NSCs). Yhhu-3792 hydrochloride activates Notch signaling pathway and promotes the expression of Hes3 and Hes5. Yhhu-3792 hydrochloride expands the NSCs pool and promotes endogenous neurogenesis in the hippocampal dentate gyrus (DG) in mouse. Yhhu-3792 hydrochloride increases the spatial and episodic memory abilities of mice. Yhhu-3792 hydrochloride has the potential for the research of impairment of learning and memory associated DG dysfunction .

HY-15036A

Diclofenac diethylamine 10+ Cited Publications	COX Apoptosis	Inflammation/Immunology Cancer
Diclofenac diethylamine is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells , and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively . Diclofenac diethylamine induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade .

HY-101796

NSC-70220	Others	Cancer
NSC-70220 is a selective and allosteric SOS1 inhibitor. NSC-70220 inhibits allosteric site activation, and partially inhibited catalytic site activation. NSC-70220 has an anticancer effect .

HY-16933

L-Alanosine 1 Publications Verification NSC-153353; SDX-102	Antibiotic	Infection Cancer
L-Alanosine (NSC-153353), an antibiotic from Streptomyces alanosinicus, has antineoplastic activity. L-Alanosine (NSC-153353) inhibits adenylosuccinate synthetase, which converts inosine monophospate (IMP) into adenylosuccinate. L-Alanosine (NSC-153353) blocks the common de novo purine biosynthesis pathway and, thereby, inhibits tumor cells with MTAP deficiency .

HY-19539

NSC-658497
NSC-658497 is an effective inhibitor of Ras-GEF, SOS1. NSC-658497 binds to SOS1, competitively suppresses SOS1-Ras interaction, and dose-dependently inhibits SOS1 GEF activity. NSC-658497 showed dose-dependent efficacy in inhibiting Ras, downstream signaling activities, and associated cell proliferation .

HY-Y1644S

NSC 8751-d6 (E)-2-Butenoic acid-d₆; (E)-Crotonic acid-d₆; trans-2-Butenoic acid-d₆; trans-Crotonic acid-d₆	Endogenous Metabolite	Metabolic Disease
NSC 8751-d₆ is the deuterium labeled NSC 8751[1]. NSC 8751 is an endogenous metabolite[2].

HY-134309

NSC 288387	Virus Protease	Infection
NSC 288387 is a pan-flavivirus MTase inhibitor. NSC 288387 binds to the SAM-binding pocket. NSC 288387 inhibits ZIKV with an IC₅₀ of 0.2 μM. NSC 288387 also inhibits viral replication in cell culture .

HY-19387

Didox

5+ Cited Publications

NSC-324360
DNA/RNA Synthesis Cancer

Didox (NSC-324360) is a synthetic ribonucleotide reductase (RR) inhibitor.

Didox 5+ Cited Publications NSC-324360	DNA/RNA Synthesis	Cancer
Didox (NSC-324360) is a synthetic ribonucleotide reductase (RR) inhibitor.

HY-Y0124S

NSC 16590-d6 α,α-Dimethylglycine-d₆; α-Aminoisobutanoic acid-d₆	Isotope-Labeled Compounds Endogenous Metabolite	Others
NSC 16590-d₆ is the deuterium labeled NSC 16590. NSC 16590 inhibits the production of endogenous ethylene in the cotyledonary segments of cocklebur.

HY-122258

NSC-370284	STAT TET Protein	Cancer
NSC-370284 is a selective inhibitor of ten-eleven translocation 1 (TET1) and 5-hydroxymethylcytosine (5hmC). NSC-370284 significantly inhibits the level of TET1 expression via targets STAT3/5 .

HY-18594

NSC-41589

Others Others

NSC-41589 is an N-[2-(methylsulfanyl) phenyl]acetamide.

NSC-41589	Others	Others
NSC-41589 is an N-[2-(methylsulfanyl) phenyl]acetamide.

HY-152168

NSC 295642	PERK Phosphatase	Cancer
NSC 295642 is a phosphatase inhibitor. NSC 295642 can significantly increase phospho-Erk cytonuclear differences in intact cells. NSC 295642 can be used for the research of cancer .

HY-79576S

NSC 88911-d3

Oestrone methyl ether-d₃; 3-O-Methylestrone-d₃
Isotope-Labeled Compounds Cancer

NSC 88911-d₃ is the deuterium labeled NSC 88911[1].
HY-52155S

NSC 89275-d12

Isotope-Labeled Compounds Others

NSC 89275-d₁₂ is the deuterium labeled NSC 89275[1].
HY-Y0085S

NSC 190686-d3

3,4-Difluorobenzoic acid-d₃
Isotope-Labeled Compounds Others

NSC 190686-d₃ is the deuterium labeled NSC 190686[1].
HY-Y0093S

NSC 5416-d14

α,ω-Nonanediol-d₁₄; 1,9-Dihydroxynonane-d₁₄; Nonamethylene Glycol-d₁₄
Isotope-Labeled Compounds Others

NSC 5416-d₁₄ is the deuterium labeled NSC 5416[1].
HY-Y0219S1

1,2,4-Triazole-d3

s-Triazole-d₃; Pyrrodiazole-d₃
Isotope-Labeled Compounds Others

NSC 83128-d₃ is the deuterium labeled NSC 83128[1].
HY-Y0226S1

NSC 1940-d8

Isotope-Labeled Compounds Others

NSC 1940-d₈ is the deuterium labeled NSC 1940[1].
HY-Y0226S2

NSC 1940-d4

Isotope-Labeled Compounds Others

NSC 1940-d₄ is the deuterium labeled NSC 1940[1].
HY-Y0251S

NSC 3120-d3

m-Nitrophthalic acid-d₃; o-Nitrophthalic acid-d₃
Isotope-Labeled Compounds Others

NSC 3120-d₃ is the deuterium labeled NSC 3120[1].
HY-Y1630S

NSC 10281-d4

Para-fluoronitrobenzene-d₄; p-Fluoronitrobenzene-d₄; p-Nitrofluorobenzene-d₄
Isotope-Labeled Compounds Others

NSC 10281-d₄ is the deuterium labeled NSC 10281[1].
HY-Y1675S

NSC 65593-d4

m-Acetylanisole-d₄; m-Methoxyacetophenone-d₄
Isotope-Labeled Compounds Others

NSC 65593-d₄ is the deuterium labeled NSC 65593[1].

NSC 88911-d3 Oestrone methyl ether-d₃; 3-O-Methylestrone-d₃	Isotope-Labeled Compounds	Cancer
NSC 88911-d₃ is the deuterium labeled NSC 88911[1].

NSC 89275-d12	Isotope-Labeled Compounds	Others
NSC 89275-d₁₂ is the deuterium labeled NSC 89275[1].

NSC 190686-d3 3,4-Difluorobenzoic acid-d₃	Isotope-Labeled Compounds	Others
NSC 190686-d₃ is the deuterium labeled NSC 190686[1].

NSC 5416-d14 α,ω-Nonanediol-d₁₄; 1,9-Dihydroxynonane-d₁₄; Nonamethylene Glycol-d₁₄	Isotope-Labeled Compounds	Others
NSC 5416-d₁₄ is the deuterium labeled NSC 5416[1].

1,2,4-Triazole-d3 s-Triazole-d₃; Pyrrodiazole-d₃	Isotope-Labeled Compounds	Others
NSC 83128-d₃ is the deuterium labeled NSC 83128[1].

NSC 1940-d8	Isotope-Labeled Compounds	Others
NSC 1940-d₈ is the deuterium labeled NSC 1940[1].

NSC 1940-d4	Isotope-Labeled Compounds	Others
NSC 1940-d₄ is the deuterium labeled NSC 1940[1].

NSC 3120-d3 m-Nitrophthalic acid-d₃; o-Nitrophthalic acid-d₃	Isotope-Labeled Compounds	Others
NSC 3120-d₃ is the deuterium labeled NSC 3120[1].

NSC 10281-d4 Para-fluoronitrobenzene-d₄; p-Fluoronitrobenzene-d₄; p-Nitrofluorobenzene-d₄	Isotope-Labeled Compounds	Others
NSC 10281-d₄ is the deuterium labeled NSC 10281[1].

NSC 65593-d4 m-Acetylanisole-d₄; m-Methoxyacetophenone-d₄	Isotope-Labeled Compounds	Others
NSC 65593-d₄ is the deuterium labeled NSC 65593[1].

HY-145330

NSC639828	DNA/RNA Synthesis	Cancer
NSC639828 is a potent inhibitor of DNA polymerase α with an IC₅₀ of 70 μM. NSC639828 has high antitumor activity. NSC639828 has the potential for researching cancer disease .

HY-N0837

Veratramine

1 Publications Verification

NSC17821; NSC23880
Others Cancer

Veratramine(NSC17821; NSC23880) is useful as a signal transduction inhibitor for treating tumors.
HY-114658

Daunomycinone

NSC-109351
Biochemical Assay Reagents Cancer

Daunomycinone (NSC-109351) is a metabolite of daunomycin. Daunomycin is an antibiotic with antitumor activity .

Veratramine 1 Publications Verification NSC17821; NSC23880	Others	Cancer
Veratramine(NSC17821; NSC23880) is useful as a signal transduction inhibitor for treating tumors.

Daunomycinone NSC-109351	Biochemical Assay Reagents	Cancer
Daunomycinone (NSC-109351) is a metabolite of daunomycin. Daunomycin is an antibiotic with antitumor activity .

HY-144444

NSC381467	EGFR	Cancer
NSC381467 is a potent and orally active inhibitor of EGFR tyrosine kinase (EGFR-TK). NSC381467 has strong antiproliferative activities. NSC381467 has the potential for the research of cancer diseases .

HY-144445

NSC114126	EGFR	Cancer
NSC114126 is a potent and orally active inhibitor of EGFR tyrosine kinase (EGFR-TK). NSC114126 has strong antiproliferative activities. NSC114126 has the potential for the research of cancer diseases .

HY-15827

NSC 405020 1 Publications Verification	MMP	Cardiovascular Disease Cancer
NSC 405020 is a specific MMP14 inhibitor. NSC 405020 can directly interact with the hemopexin domain of MMP14. NSC 405020 reduces the expression of full length and active cleaved Notch3 (NICD3). NSC 405020 can be used to research vestibular schwannoma, hemostasis and thrombosis .

HY-B0678

Metaxalone

AHR438; NSC170959
Others Neurological Disease

Metaxalone(AHR438;NSC170959) is a muscle relaxant used to relax muscles.

Metaxalone AHR438; NSC170959	Others	Neurological Disease
Metaxalone(AHR438;NSC170959) is a muscle relaxant used to relax muscles.

HY-141687

NSC 107512	CDK Apoptosis	Cancer
NSC 107512 is a potent inhibitor of cyclin-dependent kinase 9 (CDK9). NSC 107512 is a class of sangivamycin-like molecules (SLM). NSC 107512 inhibits growth and induces apoptosis of multiple myeloma tumors .

HY-12929

NSC756093 SU093
NSC756093 is a potent inhibitor of the GBP1:PIM1 interaction. NSC756093 can potentially revert resistance to paclitaxel. NSC756093 can be used for ovarian cancer research .

HY-122066

NSC47924	Others	Infection
NSC47924 is a laminin receptor (LR) inhibitor. NSC47924 affects 37/67 kDa LR cell surface localization and interaction with the cellular prion protein. NSC47924 can be used for testing prion diseases .

HY-123510

NSC-670224

Others Others

NSC-670224 is toxic to Saccharomyces cerevisiae at low micromolar concentration (LC₅₀: 3.2 μM) .
HY-Y0219S

1,2,4-Triazole-13C2,15N3

s-Triazole¹³C₂,¹⁵N₃; Pyrrodiazole¹³C₂,¹⁵N₃
Isotope-Labeled Compounds Others

NSC 83128- ¹³C₂, ¹⁵N₃ is the ¹³C and ¹⁵N labeled NSC 83128[1].
HY-118851

NSC-77053

Others Others

NSC-77053 is a potent BoNT/E inhibitor with an IC₅₀ and a K_i of 2.4 μM and 1.29 μM, respectively .

NSC-670224	Others	Others
NSC-670224 is toxic to Saccharomyces cerevisiae at low micromolar concentration (LC₅₀: 3.2 μM) .

1,2,4-Triazole-13C2,15N3 s-Triazole¹³C₂,¹⁵N₃; Pyrrodiazole¹³C₂,¹⁵N₃	Isotope-Labeled Compounds	Others
NSC 83128- ¹³C₂, ¹⁵N₃ is the ¹³C and ¹⁵N labeled NSC 83128[1].

NSC-77053	Others	Others
NSC-77053 is a potent BoNT/E inhibitor with an IC₅₀ and a K_i of 2.4 μM and 1.29 μM, respectively .

HY-B1714

NSC 601980 analog	Others	Cancer
NSC 601980 analog is the analog of the NSC601980, NSC601980 shows antitumor activity in the yeast screening experiment, which can inhibit cell proliferation in the COLO 205 and HT29 with Log GI 50 of -6.6 and -6.9 respectively.

HY-144105

NSC405640	MDM-2/p53	Cancer
NSC405640 is a potent inhibitor of the MDM2-p53 interaction. NSC405640 rescues structural p53 mutations. NSC405640 selectively inhibits the growth of cell lines with wild-type p53 .

HY-19820A

NSC45586 sodium	Akt Ser/Thr Protease	Neurological Disease Cancer
NSC45586 sodium is an inhibitor of pleckstrin homology domain and leucine-rich repeat protein phosphatase (PHLPP). NSC45586 sodium targets the PP2C phosphatase domain in PHLPP1 and PHLPP2. NSC45586 sodium can activate AKT in neurons .

HY-19820

NSC45586	Akt Ser/Thr Protease	Neurological Disease Cancer
NSC45586 is an inhibitor of pleckstrin homology domain and leucine-rich repeat protein phosphatase (PHLPP). NSC45586 targets the PP2C phosphatase domain in PHLPP1 and PHLPP2. NSC45586 can activate AKT in neurons .

HY-18756

NSC-87877	SHP2 Phosphatase Apoptosis	Others
NSC-87877 is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (SH-PTP2 and SH-PTP1), with IC₅₀ values of 0.318 μM, 0.355 μM shp2 and shp1, respectively . NSC-87877 also inhibits dual-specificity phosphatase 26 (DUSP26) .

HY-18756A

NSC-87877 disodium	SHP2 Phosphatase Apoptosis	Cancer
NSC-87877 disodium is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (SH-PTP2 and SH-PTP1), with IC₅₀ values of 0.318 μM, 0.355 μM shp2 and shp1, respectively . NSC-87877 also inhibits dual-specificity phosphatase 26 (DUSP26) .

HY-N4277

Methyl protogracillin

NSC-698793
Others Cancer

Methyl protogracillin (NSC-698793), isolated from the roots of Dioscorea opposite Thunb, exhibits strong anti-cancer activity .
HY-144441

NSC81111

EGFR Cancer

NSC81111 is a potent and orally active EGFR-TK inhibitor with an IC₅₀ of 0.15 nM. NSC81111 has anticaner effects .

Methyl protogracillin NSC-698793	Others	Cancer
Methyl protogracillin (NSC-698793), isolated from the roots of Dioscorea opposite Thunb, exhibits strong anti-cancer activity .

HY-115492

NSC668394 1 Publications Verification	PKC	Cancer
NSC668394 is a potent ezrin (Thr567) phosphorylation inhibitor, with a K_d of 12.59 μM. NSC668394 inhibit ezrin T567 phosphorylation caused by PKCΙ primarily via their binding to ezrin. NSC668394 can be used to prevent tumor metastasis .

HY-148717

NSC363998 free base	Others	Neurological Disease
NSC363998 (free base) is an orally active compound. NSC363998 (free base) can suppress rCGG90 induced neurotoxicity. NSC363998 (free base) can be used for the research of neurodegenerative disorder such as Fragile X associated tremor/ataxia syndrome (FXTAS) .

HY-118365

NSC 140873	Others	Infection Cancer
NSC 140873 is an inhibitor of the RUNX1-CBFβ interaction. NSC 140873 can be used for research of viral infection and leukemia. NSC 140873 has an unstable structure and can be converted spontaneously in solution to a benzodiazepine (Ro5-3335) .

Cat. No.	Product Name	Target	Research Area

HY-W039756

Boc-Ala-Ala-OH

NSC 334362
Amino Acid Derivatives Others

Boc-Ala-Ala-OH (NSC 334362) is an Alanine derivative. Boc-Ala-Ala-OH is used in the preparation of anti-bacterial agent .

HY-W010955

Z-Phe-Leu-OH NSC 334018	Biochemical Assay Reagents	Others
Z-Phe-Leu-OH (NSC 334018) is a substrate for carboxypeptidase Y (CPY). Z-Phe-Leu-OH is incubated with recombinant CPY to determine peptidase activity .

HY-P4663

Val-Gly-Ser-Glu NSC 350591	Peptides	Cancer
Val-Gly-Ser-Glu (NSC 350591) is an ECF-A tetrapeptide. Val-Gly-Ser-Glu dose-dependently increases the number of human eosinophils, but not neutrophils, rosetting with complement-coated sheep erythrocytes (EAC3b) .

HY-P4698

Tri-valine NSC 35938	Peptides	Metabolic Disease
Tri-valine (NSC 35938) is a polypeptide that can be separated from Creatine kinase (HY-P2799), β-enolase, Triosephosphate isomerase (HY-P2931) and glyceraldehyde 3-phosphate dehydrogenase .

HY-P4644

Tryptophylleucine NSC 286600	Peptides	Others
Tryptophylleucine (NSC 286600) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4647

Tryptophyltryptophan NSC 524592	Peptides	Others
Tryptophyltryptophan (NSC 524592) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4631

Tryptophylalanine NSC 97949	Peptides	Others
Tryptophylalanine (NSC 97949) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P5012

Cbz-Glu-Gly-OH NSC 186902	Peptides	Others
Cbz-Glu-Gly-OH (NSC 186902) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P5024

Cbz-Ile-Pro-OH NSC 333754	Peptides	Others
Cbz-Ile-Pro-OH (NSC 333754) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4711

N-β-Alanyl-β-alanine NSC 97926	Peptides	Others
N-β-Alanyl-β-alanine (NSC 97926) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0837

Veratramine 1 Publications Verification NSC17821; NSC23880	Alkaloids Piperidine Alkaloids other families Classification of Application Fields Source classification Plants Disease Research Fields Cancer	Others
Veratramine(NSC17821; NSC23880) is useful as a signal transduction inhibitor for treating tumors.

HY-N4277

Methyl protogracillin NSC-698793	Other Terpenoids other families Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Cancer	Others
Methyl protogracillin (NSC-698793), isolated from the roots of Dioscorea opposite Thunb, exhibits strong anti-cancer activity .

HY-Y0057

NSC 13138 Cinchoninic acid (6CI,7CI,8CI); 4-Carboxyquinoline	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NSC 13138 is an endogenous metabolite.

HY-114557

NSC 90469 3,5-Diiodo-L-thyronine	Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NSC 90469 is an endogenous metabolite.

HY-Y1644

NSC 8751 (E)-2-Butenoic acid; (E)-Crotonic acid; trans-2-Butenoic acid; trans-Crotonic acid; trans-3-Methylacrylic acid	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NSC 8751 is an endogenous metabolite.

HY-13555

β-Lapachone 5+ Cited Publications ARQ-501; NSC-26326	Quinones Structural Classification other families Classification of Application Fields Source classification Plants Naphthalene Quinones Disease Research Fields Cancer	Topoisomerase Autophagy Apoptosis
β-Lapachone (ARQ-501;NSC-26326) is a naturally occurring O-naphthoquinone, acts as a topoisomerase I inhibitor, and induces apoptosis by inhibiting cell cycle progression.

HY-13764

Tetrandrine 5+ Cited Publications NSC-77037; d-Tetrandrine	Stephania tetrandra S. Moore Alkaloids Structural Classification Classification of Application Fields Source classification Plants Menispermaceae Inflammation/Immunology Disease Research Fields Alkaloid Dimers	Calcium Channel Potassium Channel Parasite
Tetrandrine (NSC-77037; d-Tetrandrine) is a bis-benzyl-isoquinoline alkaloid, which inhibits voltage-gated Ca ²⁺ current (ICa) and Ca ²⁺-activated K ⁺ current.

HY-15733

Lucidin 1 Publications Verification NSC 30546	Quinones Classification of Application Fields Anthraquinones Source classification Rubiaceae Phenols Polyphenols Plants Disease Research Fields Cancer Rubia cordifolia L.	Others
Lucidin (NSC 30546) is a natural component of Rubia cordifolia.

HY-79494

Glyoxalic acid 1 Publications Verification NSC 27785; Formylformic acid; Oxalaldehydic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Other Diseases Endocrine diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Glyoxalic acid (NSC 27785) is an organic compound that is both an aldehyde and a carboxylic acid.

HY-112058

Distamycin A NSC-82150	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Apoptosis
Distamycin A (NSC-82150), an oligopeptide antibiotic, is a minor groove binder which binds to B-form DNA, preferentially at A/T rich sites.Distamycin A can change Enediyne-induced DNA cleavage sites and enhances apoptosis .

HY-Y0124

NSC 16590 α,α-Dimethylglycine; α-Aminoisobutanoic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Pterocarpus soyauxii Taub. Source classification Other Diseases Plants Compositae Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NSC 16590 inhibits the production of endogenous ethylene in the cotyledonary segments of cocklebur.

HY-N0004

Oridonin Maximum Cited Publications 16 Publications Verification NSC-250682; Isodonol	Infection Structural Classification Classification of Application Fields Terpenoids Labiatae Diterpenoids Plants Emilia sonchifolia (L.) DC. Inflammation/Immunology Disease Research Fields	Akt Bacterial
Oridonin (NSC-250682), a diterpenoid isolated from Rabdosia rubescens, acts as an inhibitor of AKT, with IC₅₀s of 8.4 and 8.9 μM for AKT1 and AKT2; Oridonin possesses anti-tumor, anti-bacterial and anti-inflammatory effects.

HY-N1293

Serpentinine NSC72123	Apocynaceae Rauvolfia verticillata (Lour.) Baill. Structural Classification Alkaloids Rauvolfia serpentina Source classification Plants Indole Alkaloids	Others
Serpentinine (NSC72123) is an alkaloid isolated from Rauwolfia serpentina Benth .

HY-15753

Ellipticine 3 Publications Verification NSC 71795	Apocynaceae Alkaloids Classification of Application Fields Source classification Plants Amsonia elliptica (Thunberg ex Murray) Roemer & Schultes Disease Research Fields Indole Alkaloids Cancer	Topoisomerase
Ellipticine (NSC 71795) is a potent antineoplastic agent; inhibits DNA topoisomerase II activities.

HY-15753A

Ellipticine hydrochloride 3 Publications Verification NSC 71795 hydrochloride	Apocynaceae Alkaloids Structural Classification Classification of Application Fields Source classification Plants Amsonia elliptica (Thunberg ex Murray) Roemer & Schultes Disease Research Fields Indole Alkaloids Cancer	Topoisomerase
Ellipticine (NSC 71795) hydrochloride is a potent antineoplastic agent; inhibits DNA topoisomerase II activities.

HY-N3738

Demethoxycentaureidin NSC 689466	Structural Classification Flavonoids Flavones Source classification Peucephyllum schottii A.Gray Plants Compositae	Others
Demethoxycentaureidin (NSC 689466) is a natural product that can be isolated from Peucephyllum schottii .

HY-N0034

Arctiin 3 Publications Verification Arctii; NSC 315527; Arctigenin-4-glucoside	Structural Classification Natural Products Classification of Application Fields Anti-aging Source classification Lignans Phenylpropanoids Plants Compositae Caesalpinia magnifoliolata Metc. Disease Research Fields Cancer	NF-κB
Arctiin (NSC 315527) is a plant lignan extracted from burdock seeds and has anti-cancer activity.

HY-B0504

Creatinine 2 Publications Verification NSC13123	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease markers Metabolic Disease Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Creatinine(NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.

HY-N0841

Bruceine A 3 Publications Verification Dihydrobrusatol; NSC310616	Infection Triterpenes Simaroubaceae Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Brucea javanica (L.) Merr.	Parasite Antibiotic
Bruceine A(NSC310616; Dihydrobrusatol) is a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.

HY-105529

Indicine N-oxide (+)-Indicine N-oxide; NSC 132319	Alkaloids Structural Classification Pyrrole Alkaloids Classification of Application Fields Tournefortia argentea Linnaeus f. Source classification Plants Disease Research Fields Boraginaceae Cancer	Others
Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, is an antitumor agent for pediatric cancer and solid tumors research .

HY-N10687

Saprorthoquinone NSC 648341	Quinones Structural Classification Labiatae Source classification Plants Naphthalene Quinones Vachellia nilotica (L.) P. J. H. Hurter & Mabb.	Others
Saprorthoquinone (NSC 648341) is a diterpenoid that can be found in salvia atropatana. Saprorthoquinone shows cytotoxicity for PC3 cells .

HY-N0863

Methyl protodioscin NSC-698790; Smilax saponin B	other families Classification of Application Fields Source classification Plants Disease Research Fields Steroids Cancer	Apoptosis
Methyl protodioscin(NSC-698790) is a furostanol bisglycoside with antitumor properties; shows to reduce proliferation, cause cell cycle arrest.

HY-114502

Chrysanthemic acid NSC 11779	Structural Classification Tanacetum cinerariifolium (Treviranus) Schultz Bipontinus Ketones, Aldehydes, Acids Source classification Plants Compositae	Others
Chrysanthemic acid (NSC 11779) is an organic compound that is associated with a variety of natural and synthetic insecticides for the prevention of insect-borne diseases, among others .

HY-114772

Methyl reserpate NSC 81464; Me reserpate	Apocynaceae Structural Classification Alkaloids Source classification Rauvolfia vomitoria Afzel. Plants	Others
Methyl reserpate (NSC 81464) is a Yohimbine (HY-12715) type alkaloid, that can be isolated from Rauwolfia vomitoria roots and leaves .

HY-118166

Gentisein NSC 329491; 1,3,7-Trihydroxyxanthone	other families Xanthones Classification of Application Fields Neurological Disease Source classification Phenols Polyphenols Plants Disease Research Fields	5-HT Receptor
Gentisein (NSC 329491), the major metabolite of Mangiferin, shows the most potent serotonin uptake inhibition with an IC₅₀ value of 4.7 µM .

HY-N4315

Pomiferin NSC 5113	Classification of Application Fields Source classification Phenols Polyphenols Maclura pomifera (Raf.) Schneid. Plants Moraceae Disease Research Fields Cancer	HDAC mTOR
Pomiferin (NSC 5113) acts as an potential inhibitor of HDAC, with an IC₅₀ of 1.05 μM, and also potently inhibits mTOR (IC₅₀, 6.2 µM).

HY-105697

Protoveratrine A NSC 7526; Protalba; Protoveratrin	Structural Classification Alkaloids Piperidine Alkaloids Veratrum nigrum Linn. Liliaceae Source classification Plants	Others
Protoveratrine A (NSC 7526; Protalba; Protoveratrin) is an alkaloid with strong cardiostimulant and vasoconstrictive effects, which can be used in the study of hypertension and other cardiovascular diseases .

HY-N1107

Uzarigenin NSC 119993; NSC 277290; Odorigeni	Apocynaceae Structural Classification Cardiacglycosides Source classification Plants Steroids	Others
Uzarigenin (NSC 119993; NSC 277290; Odorigeni) is a carnolide can be isolated from Pergularia tomentosa and exhibits antiproliferative activity. Uzarigenin resists the proliferation of PC3 cells, HeLa cells, Calu-1 cells, MCF-7 cells and U251MG cells, with IC₅₀ values of 0.3 μM, 3.0 μM, 8.0 μM, 6.0 μM and 6.0 μM respectively .

HY-N1393

2-Methoxybenzoic acid NSC 3778; O-Methylsalicylic acid; Salicylic acid methyl ether	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
2-Methoxybenzoic acid (NSC 3778) is used as an internal standard of salicylic acid and its putative biosynthetic precursors in cucumber leaves. Another known use is in the synthesis of Benextramine.

HY-114917

Aldophosphamide NSC 254	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Drug Metabolite Endogenous Metabolite
Aldophosphamide (NSC 254) is a cyclophosphamide metabolite. Aldophosphamide is cleaved intracellularly to phosphoramide mustard, an active metabolite with direct cytotoxicity, and acrolein. Aldophosphamide has potential for cancer research .

HY-Y0148

10-Hydroxydecanoic acid NSC 15139	Structural Classification Classification of Application Fields Animals Ketones, Aldehydes, Acids Source classification Inflammation/Immunology Disease Research Fields	Others
10-Hydroxydecanoic acid (NSC 15139) is a saturated fatty acid of 10-hydroxy-trans-2-decenoic acid from royal jelly, with anti-inflammatory activity .

HY-N1375

Qingyangshengenin	Monophenols Classification of Application Fields Source classification Asclepiadaceae Phenols Cynanchum otophyllum Schneid． Plants Disease Research Fields Steroids Cancer	Others
Qingyanshengenin (NSC 379666; compound 2), a pregnane glycoside, is a C21 steroidal aglycone isolated from the root of Cynanchumot ophyllum (Asclepiadaceae). Qingyanshengenin has anti-cancer activity .

HY-118384

Sangivamycin 2 Publications Verification NSC 65346; BA-90912	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields Cancer	PKC Nucleoside Antimetabolite/Analog
Sangivamycin (NSC 65346), a nucleoside analog, is a potent inhibitor of protein kinase C (PKC) with an K_i of 10 μM. Sangivamycin has potent antiproliferative activity against a variety of human cancers .

HY-101413

Iberin 1 Publications Verification NSC 321801	Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Endogenous metabolite Disease Research Fields Cancer	Apoptosis Endogenous Metabolite Bacterial
Iberin (NSC 321801), a sulfoxide analogue of sulforaphane, is a naturally occurring member of isothiocyanate family. Iberin inhibits cell survival with an IC₅₀ of 2.3 μM in HL60 cell. Iberin induces apoptosis.

HY-N0840

Bruceantin 1 Publications Verification (-)-Bruceantin; NCI165563; NSC165563	Simaroubaceae Classification of Application Fields Brucea antidysenterica J.F.Mill. Terpenoids Source classification Diterpenoids Plants Disease Research Fields Cancer Brucea javanica (L.) Merr.	Others
Bruceantin(NSC165563) is first isolated from Brucea javanica, a tree used in Ethiopia for the treatment of cancer, and activity was observed against B16 melanoma, colon 38, and L1210 and P388 leukemia in mice.

HY-B0751

Fumagillin Amebacilin; NSC9168	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Parasite HIV Antibiotic
Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.

HY-32736

Triptonide 2 Publications Verification NSC 165677; PG 492	Classification of Application Fields Terpenoids Source classification Celastraceae Diterpenoids Plants Tripterygium wilfordii Hook. f. Disease Research Fields Inflammation/Immunology	Wnt β-catenin Apoptosis Autophagy
Triptonide (NSC 165677) is a natural product identified in Tripterygium wilfordii Hook F.. Triptonide is a Wnt signaling inhibitor with an IC₅₀ of appropriately 0.3 nM. Triptonide has immunosuppression, anti-inflammatory, anti-fertility, neuroprotective and anti-lymphoma effects .

HY-N3627

Coronalolide methyl este NSC 680073	Structural Classification Natural Products Source classification Rubiaceae Plants Gardenia jasminoides Ellis	Others
Coronalolide methyl ester (NSC 680073) is a natural triterpene with anticancer effects. Coronalolide methyl ester shows moderately cytotoxic to KATO-3, SW-620, and Hep-G2 cells., with IC₅₀ values of 8.64 µg/mL, 6.19 µg/mL, and 6.8 µg/mL, respectively .

HY-17470

Mizoribine 4 Publications Verification NSC 289637; HE 69	Alkaloids Structural Classification Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields	HCV SARS-CoV Antibiotic Parasite
Mizoribine (NSC 289637), an imidazole nucleoside, inhibits HCV RNA replication with IC₅₀ of approximately 100 μM for anti-HCV activity. Immunosuppressant . Mizoribine, an IMPDH inhibitor, inhibits replication of SARS-CoV with IC₅₀s of 3.5 μg/mL and 16 μg/mL for SARS-CoV Frankfurt-1 and SARS-CoV HKU39849, respectively .

HY-N6703

ar-Turmerone (+)-ar-Turmerone	Natural Products Classification of Application Fields Source classification Plants Curcuma longa Disease Research Fields Inflammation/Immunology Zingiberaceae	Apoptosis
ar-Turmerone ((+)-ar-Turmerone) is a major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities . ar-Turmerone activates apoptotic protein in human lymphoma U937 cells . ar-Turmerone exerts positive modulation on murine DCs. ar-Turmerone induces NSC proliferation and constitutes a promising therapeutic agent for various neurologic disorders .

HY-134000

Emodic acid NSC624610	Quinones Structural Classification Human Gut Microbiota Metabolites Microorganisms Leguminosae Cercis chinensis Bunge Anthraquinones Source classification Plants Endogenous metabolite	p38 MAPK NF-κB ERK JNK VEGFR MMP
Emodic acid (NSC624610) is an anthraquinone compound isolated from A. microcarpus, which can inhibit the proliferation of cancer cells by inhibiting the activity of NF-κB. Emodic acid can also inhibit the phosphorylation of p38, ERK and JNK, the secretion of tumor-promoting cytokines IL-1β and IL-6, and the expression of VEGF and MMP, thereby inhibiting the invasion and migration potential of cancer cells .

HY-N0142

Phloretin 10+ Cited Publications NSC 407292; RJC 02792	Structural Classification Classification of Application Fields Source classification Rosaceae Plants Dihydrochalcones Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Microorganisms Malus pumila Mill. Phenols Polyphenols Disease Research Fields Cancer	SGLT Endogenous Metabolite GLUT
Phloretin (NSC 407292; RJC 02792) is a flavonoid extracted from Malus pumila Mill., has anti-inflammatory activities. Phloridzin is a specific, competitive and orally active inhibitor of sodium/glucose cotransporters in the intestine (SGLT1) and kidney (SGLT2). Phloretin inhibits Yeast-made GLUT1 as well as Human erythrocyte GLUT1 with IC₅₀values of 49 μM and 61 μM, respectively .Phloretin has the potential for the treatment of rheumatoid arthritis (RA) and allergic airway inflammation .

HY-N0142R

Phloretin (Standard) NSC 407292 (Standard); RJC 02792 (Standard)	Structural Classification Human Gut Microbiota Metabolites Flavonoids Classification of Application Fields Source classification Malus pumila Mill. Rosaceae Phenols Plants Endogenous metabolite Disease Research Fields Cancer	SGLT Endogenous Metabolite GLUT
Phloretin (Standard) is the analytical standard of Phloretin. This product is intended for research and analytical applications. Phloretin (NSC 407292; RJC 02792) is a flavonoid extracted from Malus pumila Mill., has anti-inflammatory activities. Phloridzin is a specific, competitive and orally active inhibitor of sodium/glucose cotransporters in the intestine (SGLT1) and kidney (SGLT2). Phloretin inhibits Yeast-made GLUT1 as well as Human erythrocyte GLUT1 with IC₅₀values of 49 μM and 61 μM, respectively .Phloretin has the potential for the treatment of rheumatoid arthritis (RA)?and allergic airway inflammation .

Cat. No.	Product Name	Chemical Structure

HY-Y1644S

NSC 8751-d6

NSC 8751-d₆ is the deuterium labeled NSC 8751[1]. NSC 8751 is an endogenous metabolite[2].
HY-Y0124S

NSC 16590-d6

NSC 16590-d₆ is the deuterium labeled NSC 16590. NSC 16590 inhibits the production of endogenous ethylene in the cotyledonary segments of cocklebur.
HY-79576S

NSC 88911-d3

NSC 88911-d₃ is the deuterium labeled NSC 88911[1].
HY-52155S

NSC 89275-d12

NSC 89275-d₁₂ is the deuterium labeled NSC 89275[1].
HY-Y0085S

NSC 190686-d3

NSC 190686-d₃ is the deuterium labeled NSC 190686[1].
HY-Y0093S

NSC 5416-d14

NSC 5416-d₁₄ is the deuterium labeled NSC 5416[1].
HY-Y0219S1

1,2,4-Triazole-d3

NSC 83128-d₃ is the deuterium labeled NSC 83128[1].
HY-Y0226S1

NSC 1940-d8

NSC 1940-d₈ is the deuterium labeled NSC 1940[1].
HY-Y0226S2

NSC 1940-d4

NSC 1940-d₄ is the deuterium labeled NSC 1940[1].
HY-Y0251S

NSC 3120-d3

NSC 3120-d₃ is the deuterium labeled NSC 3120[1].
HY-Y1630S

NSC 10281-d4

NSC 10281-d₄ is the deuterium labeled NSC 10281[1].
HY-Y1675S

NSC 65593-d4

NSC 65593-d₄ is the deuterium labeled NSC 65593[1].
HY-Y0219S

1,2,4-Triazole-13C2,15N3

NSC 83128- ¹³C₂, ¹⁵N₃ is the ¹³C and ¹⁵N labeled NSC 83128[1].
HY-B0678S

Metaxalone-d3

Metaxalone-d₃ is the deuterium labeled Metaxalone. Metaxalone (AHR438;NSC170959) is a muscle relaxant used to relax muscles.

HY-17393S

Carboplatin-d4
Carboplatin-d₄ is the deuterium labeled Carboplatin. Carboplatin (NSC 241240) is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death. Carboplatin (NSC 241240) is a derivative of CDDP and a potent anti-cancer agent.

HY-W017475S

4-Nitrobenzonitrile-d4

4-Nitrobenzonitrile-d₄ is the deuterium labeled NSC 88911[1].
HY-W016389S

9H-Fluoren-2-ol-d9

9H-Fluoren-2-ol-d₉ (NSC 31248-d₉) is a deuterium labeled compound.

HY-N0055S

Chlorogenic acid-13C3

Chlorogenic acid- ¹³C₃ (Heriguard- ¹³C₃; NSC-407296- ¹³C₃) is ¹³C- and ¹⁵N-labeled Chlorogenic acid (HY-N0055). Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb.. It plays several important and therapeutic roles such as antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension .

HY-B0504S2

Creatinine-d5
Creatinine-d₅ is the deuterium labeled Creatinine. Creatinine (NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.

HY-123533S

Resorufin-d6

Resorufin-d₆ is the deuterium labeled Resorufin. Resorufin (NSC 12097) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte[1].

HY-B0504S1

Creatinine-13C
Creatinine- ¹³C is the ¹³C-labeled Creatinine. Creatinine (NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.

HY-79576S2

NSC 88911-13C6

NSC 88911- ¹³C₆ is a ¹³C-labeled 3-(4-Chlorophenyl)-1-methoxy-1-methylurea[1].

HY-N5034S

Phosphorylethanolamine-d4
Phosphorylethanolamine-d₄ (Monoaminoethyl phosphate-d₄; NSC 254167-d₄) is a deuterium labeled Phosphorylethanolamine (HY-N5034). Phosphorylethanolamine is an endogenous metabolite.

HY-B0246S3

Carbamazepine-(Ph)d8

Carbamazepine-(Ph)d8 (CBZ-(Ph)d8; NSC 169864-(Ph)d8) is the deuterium labeled Carbamazepine-(Ph) (HY-B0246) .
HY-B0139S

Flucytosine-13C,15N2

Flucytosine- ¹³C, ¹⁵N₂ (NSC 103805- ¹³C, ¹⁵N₂; Ro 2-9915- ¹³C, ¹⁵N₂) is a ¹³C- and ¹⁵N-labeled Flucytosine (HY-B0139).

HY-N1393S

2-Methoxybenzoic acid-13C6
2-Methoxybenzoic acid- ¹³C₆ is the ¹³C-labeled 2-Methoxybenzoic acid. 2-Methoxybenzoic acid (NSC 3778) is used as an internal standard of salicylic acid and its putative biosynthetic precursors in cucumber leaves. Another known use is in the synthesis of Benextramine.

HY-14655S

Sulfasalazine-d4
Sulfasalazine-d₄ is the deuterium labeled Sulfasalazine. Sulfasalazine (NSC 667219) is an anti-rheumatic agent for the research of rheumatoid arthritis and ulcerative colitis. Sulfasalazine can suppress NF-κB activity. Sulfasalazine is a type 1 ferroptosis inducer[1][2][3][4].

HY-N1150S10

Thymidine-d14
Thymidine-d₁₄ (DThyd-d₁₄; NSC 21548-d₁₄) is deuterium labeled Thymidine (HY-N1150). Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.

HY-N1150S11

Thymidine-13C10
Thymidine- ¹³C₁₀ (DThyd- ¹³C₁₀; NSC 21548- ¹³C₁₀) is ¹³C-labeled Thymidine (HY-N1150). Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.

HY-17364S

Temozolomide-d3

Temozolomide-d₃ is the deuterium labeled Temozolomide. Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects[1][2].

HY-13768S1

Topotecan-d6
Topotecan-d₆ is the deuterium labeled Topotecan. Topotecan (SKF 104864A; NSC 609669) is a Topoisomerase I inhibitor. The IC50 values of Topotecan at 24 h are 2.73±0.25 μM of U251 cells, 2.95±0.23 μM of U87 cells, 5.46±0.41 μM of GSCs-U251 and 5.95 μM of GSCs-U87[1][2].

HY-N6746S1

Citrinin-13C13

Citrinin- ¹³C₁₃ (NSC 186- ¹³C₁₃) is the ¹³C labeled Citrinin (HY-N6746) . Citrinin is a mycotoxin which causes contamination in the food and is associated with different toxic effects. Citrinin is usually found together with another nephrotoxic mycotoxin, Ochratoxin A. Citrinin is also reported to possess a broad spectrum of bioactivities, including antibacterial, antifungal, and potential anticancer and neuro-protective effects in vitro .

HY-B1221S

Flufenamic acid-d4

Flufenamic acid-d₄ is deuterium labeled Flufenamic acid. Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca ²⁺ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation.

HY-15036S1

Diclofenac-13C6
Diclofenac- ¹³C₆ is the ¹³C₆ labeled Diclofenac. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.

HY-15037S2

Diclofenac-13C6 sodium

Diclofenac- ¹³C₆ (Sodium) is the ¹³C₆ labeled Diclofenac (Sodium). Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.

HY-B1221S1

Flufenamic acid-13C6

Flufenamic acid- ¹³C₆ is the ¹³C₆ labeled Flufenamic acid. Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca ²⁺ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation.

HY-15037S1

Diclofenac-d4 sodium

Diclofenac-d₄ (sodium) is the deuterium labeled Diclofenac sodium. Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].

HY-15036S

Diclofenac-d4
Diclofenac-d₄ is the deuterium labeled Diclofenac. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].

HY-N6703S

ar-Turmerone-d3

ar-Turmerone-d₃ is the deuterium labeled ar-Turmerone. ar-Turmerone ((+)-ar-Turmerone) is a major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities[1][2][3]. ar-Turmerone activates apoptotic protein in human lymphoma U937 cells[3]. ar-Turmerone exerts positive modulation on murine DCs. ar-Turmerone induces NSC proliferation and constitutes a promising therapeutic agent for various neurologic disorders[4][5].

HY-15037S

Diclofenac-13C6 sodium heminonahydrate

Diclofenac- ¹³C₆ (sodium heminonahydrate) is the ¹³C-labeled Diclofenac Sodium. Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].

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