Search Result

Results for "

NT

" in MedChemExpress (MCE) Product Catalog:

By Targets:	c-Myc (1) CXCR (1) Drug Metabolite (2) Endogenous Metabolite (2) HDAC (1) iGluR (1) Insulin Receptor (1) Interleukin Related (1) Isotope-Labeled Compounds (1) Liposome (2) Neurokinin Receptor (1) Neurotensin Receptor (4) NOD-like Receptor (NLR) (2) Small Interfering RNA (siRNA) (9) STAT (1) Trk Receptor (2)
By Research Areas:	Cancer (8) Cardiovascular Disease (1) Inflammation/Immunology (2) Metabolic Disease (1) Neurological Disease (13)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: CD73

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-100037

NT157 1 Publications Verification Tyrphostin NT157
NT157 (Tyrphostin NT157) is a selective IRS-1/2 inhibitor that induces Ser-phosphorylation and consequently the degradation of IRS-1/2. NT157 (Tyrphostin NT157) is a first-in-class anti-cancer agent that also targets Stat3 signaling pathway .

HY-137500

NT1-014B	Liposome	Neurological Disease
NT1-014B is a potent NT1-lipidoid encapsulated AmB (amphotericin B). NT1-014B dopes the NT-lipidoids into BBB-impermeable lipid nanoparticles (LNPs) gave the LNPs the ability to cross the BBB. NT1-014B enhances brain delivery through intravenous injection .

HY-161297

NT-0249

NOD-like Receptor (NLR) Inflammation/Immunology

NT-0249 is an orally active NLRP3 inhibitor. NT-0249 has anti-inflammatory activity

NT-0249	NOD-like Receptor (NLR)	Inflammation/Immunology
NT-0249 is an orally active NLRP3 inhibitor. NT-0249 has anti-inflammatory activity

HY-156438

NT-0796	NOD-like Receptor (NLR)	Neurological Disease
NT-0796 is a selective and CNS-penetrant NLRP3 inflammasome inhibitor with an IC₅₀ of 0.32 nM in PBMC assay. NT-0796 is an isopropyl ester that undergoes intracellular conversion to NDT-19795, the carboxylic acid active species. NT-0796 has the potential for neuroinflammatory diseases research .

HY-P7060

NT 13 TPPT	iGluR	Neurological Disease
NT 13 (TPPT) is a tetrapeptide having the amino acid sequence L-threonyl-L-prolyl-L-prolyl-L-threonine amide. NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.

HY-149285

NT160	HDAC	Neurological Disease
NT160 is a highly potent class-IIa HDAC inhibitor with an IC₅₀ value of 0.046 μM. NT160 can be used for the research of central nervous system diseases .

HY-137499

NT1-O12B	Liposome Endogenous Metabolite	Neurological Disease
NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .

HY-145935

NT219	Insulin Receptor STAT	Cancer
NT219 is a potent and dual inhibitor of insulin receptor substrates 1/2 (IRS1/2) and STAT3. IRS1/2 and STAT3 are major signaling junctions regulated by various oncogenes. NT219 affects IRS1/2 degradation and inhibits STAT3 phosphorylation. NT219 has the potential for the research of cancer diseases .

HY-161127

NT-B2R

c-Myc Cancer

NT-B2R is a potent MYC inhibitor. NT-B2R inhibited MYC transcriptional activity and cell proliferation .

NT-B2R	c-Myc	Cancer
NT-B2R is a potent MYC inhibitor. NT-B2R inhibited MYC transcriptional activity and cell proliferation .

HY-109171

Elinzanetant NT-814; BAY3427080	Neurokinin Receptor	Cardiovascular Disease Neurological Disease
Elizanetant (NT-814) is an orally active, selective NK-1,3 receptor antagonist. Elizanetant can be used in vasomotor and schizophrenia studies .

HY-P99908

Efineptakin alfa NT-17	Interleukin Related	Cancer
Efineptakin alfa (NT-17) is a long-acting recombinant human IL-7. Efineptakin alfa supports the proliferation and survival CD4 ⁺ and CD8 ⁺ cells in both human and mice. Efineptakin alfa can be used for glioblastoma research .

HY-RS09607

NT5C Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NT5C Human Pre-designed siRNA Set A contains three designed siRNAs for NT5C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NT5C Human Pre-designed siRNA Set A NT5C Human Pre-designed siRNA Set A

HY-RS09612

NT5E Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NT5E Human Pre-designed siRNA Set A contains three designed siRNAs for NT5E gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NT5E Human Pre-designed siRNA Set A NT5E Human Pre-designed siRNA Set A

HY-RS09613

Nt5e Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Nt5e Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nt5e gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Nt5e Mouse Pre-designed siRNA Set A Nt5e Mouse Pre-designed siRNA Set A

HY-RS09614

Nt5e Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Nt5e Rat Pre-designed siRNA Set A contains three designed siRNAs for Nt5e gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Nt5e Rat Pre-designed siRNA Set A Nt5e Rat Pre-designed siRNA Set A

HY-RS09615

NT5M Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NT5M Human Pre-designed siRNA Set A contains three designed siRNAs for NT5M gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NT5M Human Pre-designed siRNA Set A NT5M Human Pre-designed siRNA Set A

HY-RS09609

NT5C2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NT5C2 Human Pre-designed siRNA Set A contains three designed siRNAs for NT5C2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NT5C2 Human Pre-designed siRNA Set A NT5C2 Human Pre-designed siRNA Set A

HY-RS09610

NT5DC1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NT5DC1 Human Pre-designed siRNA Set A contains three designed siRNAs for NT5DC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NT5DC1 Human Pre-designed siRNA Set A NT5DC1 Human Pre-designed siRNA Set A

HY-RS09611

NT5DC2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NT5DC2 Human Pre-designed siRNA Set A contains three designed siRNAs for NT5DC2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NT5DC2 Human Pre-designed siRNA Set A NT5DC2 Human Pre-designed siRNA Set A

HY-RS09608

NT5C1A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NT5C1A Human Pre-designed siRNA Set A contains three designed siRNAs for NT5C1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NT5C1A Human Pre-designed siRNA Set A NT5C1A Human Pre-designed siRNA Set A

HY-106856

Dimiracetam NT-11624	Others	Cancer
Dimiracetam is an orally active compound, with anti-neuropathic activity. Dimiracetam inhibits hypersensitivity and neurological alterations, and inhibits Sorafenib (HY-10201)-induced neuropathy in cold stimulation rat models .

HY-P4109

vMIP-II (1-21) NT21MP; V1 peptide	CXCR	Inflammation/Immunology Cancer
vMIP-II (1-21) is a CXCR4 antagonist. vMIP-II has broad-spectrum interaction with CC and CXC chemokine receptors. vMIP-II (1-21) binds with CXCR4 with an IC₅₀ value of 190 nM for competing with CXCR4 binding of 125I-SDF-1R .

HY-P3057

[D-Trp11]-Neurotensin	Neurotensin Receptor	Neurological Disease
[D-Trp11]-Neurotensin, an analogue of Neurotensin (NT), is a selective antagonist of NT in perfused rat hearts but behaves as a full agonist in guinea pig atria and rat stomach strips. [D-Trp11]-Neurotensin can inhibit NT-induced hypotension .

HY-U00050

(E)-10-Hydroxynortriptyline E-10-OH-NT	Drug Metabolite	Neurological Disease
(E)-10-Hydroxynortriptyline (E-10-OH-NT) is a metabolite of Nortriptyline (HY-B1417). Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline (HY-B0527A) . E-10-OH-NT is about 50% as potent as nortriptyline as an inhibitor of the neuronal uptake of norepinephrine in vitro and exhibits less anticholinergic effects in man.

HY-107664A

SR 142948 dihydrochloride	Neurotensin Receptor	Neurological Disease
SR 142948 dihydrochloride is an orally active and selective non-peptide neurotensin receptor (NT) antagonist with IC₅₀s of 1.19 nM, 0.32 nM, 3.96 nM in h-NTR1-CHO cells, HT-29 cells, and adult rat brain, respectively. SR 142948 dihydrochloride antagonizes NT-induced inositol monophosphate formation in HT-29 cells with an IC₅₀ of 3.9 nM. SR 142948 dihydrochloride blocks hypothermia, analgesia and steering behavior induced by NT in vivo. SR 142948 dihydrochloride shows blood-brain permeability and can be used in study of psychiatric disorders .

HY-153843

RNA Aptamer Corn sodium	Others	Others
RNA Aptamer Corn (sodium) is a 28-nt-long aptamer that is substantially shorter than Spinach and Spinach2 and exhibits bright red fluorescence upon binding DFHO (a soluble analog of the intrinsic fluorophore of red fluorescent protein), RNA Aptamer Corn (sodium) can be used to visualize RNA expression or localization in live cells which have been soaked with chromophores. The Corn-DFHO does not become appreciably cytotoxic when illuminated. And most importantly, Corn-DFHO exhibits markedly increased photostability compared to other aptamer-chromophore complexes both in vitro and in vivo. (36 nt Corn construct: 5'-GGCGCGAGGAAGGAGGUCUGAGGAGGUCACUGCGCC-3'; A 36-nt RNA construct, comprised of the 28-nt minimal Corn sequence extended proximally with a 4 base-pair stem.)

HY-146524

TRK-IN-18	Trk Receptor	Cancer
TRK-IN-18 is a potent inhibitor of TRK. Tropomyosin-related kinases (Trks) are a family of receptor tyrosine kinases activated by neurotrophins, a group of soluble growth factors including Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF) and Neurotrophin-3 (NT-3) and Neurotrophin-4/5 (NT-4/5). TRK-IN-18 has the potential for the research of cancer diseases (extracted from patent WO2021148805A1, compound 7) .

HY-146523

TRK-IN-17	Trk Receptor	Cancer
TRK-IN-17 is a potent inhibitor of TRK. Tropomyosin-related kinases (Trks) are a family of receptor tyrosine kinases activated by neurotrophins, a group of soluble growth factors including Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF) and Neurotrophin-3 (NT-3) and Neurotrophin-4/5 (NT-4/5). TRK-IN-17 has the potential for the research of cancer diseases (extracted from patent WO2021148807A1, compound 3) .

HY-107761

JMV 390-1	Others	Neurological Disease
JMV 390-1 (Compound 6a) is a potent multipeptidase inhibitor. JMV 390-1 behaves as a full inhibitor of the major neurotensin (NT)/neuromedin N (NN) degrading enzymes in vitro with IC₅₀ values from 30 to 60 nM. JMV 390-1 increases endogenous recovery of NT and NN from slices of mice hypothalamus depolarized with potassium .

HY-107664

SR 142948	Neurotensin Receptor	Neurological Disease
SR 142948 is an orally active and selective non-peptide neurotensin receptor (NT) antagonist with IC₅₀s of 1.19 nM, 0.32 nM, 3.96 nM in h-NTR1-CHO cells, HT-29 cells, and adult rat brain, respectively. SR 142948 antagonizes NT-induced inositol monophosphate formation in HT-29 cells with an IC50 of 3.9 nM. SR 142948 blocks hypothermia, analgesia and steering behavior induced by NT in vivo. SR 142948 shows blood-brain permeability and can be used in study of psychiatric disorders .

HY-P0251

Neurotensin(8-13) 1 Publications Verification	Neurotensin Receptor	Neurological Disease
Neurotensin (8-13) is an active fragment of Neurotensin. Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.

HY-P3260

5′-Nucleotidase, Microorganism CD73; 5′-NT	Endogenous Metabolite	Metabolic Disease
5′-Nucleotidase, Microorganism (CD73) is an intrinsic membrane glycoprotein present as an ectoenzyme. 5′-Nucleotidase catalyzes hydrolysis of 5-nucleotides to their corresponding nucleosides .

HY-160044

Apt-M13 aptamer sodium	Others	Cancer
Apt-M13 aptamer sodium is a mutant 33 nt aptamer based on the original aptamer for dexamethasone (HY-14648). Apt-M13 aptamer sodium can be combined with other nanomaterials for rapid detection of dexamethasone (HY-14648) .

HY-U00050S

(E)-10-Hydroxynortriptyline-d3 E-10-OH-NT-d₃	Isotope-Labeled Compounds Drug Metabolite	Neurological Disease
(E)-10-Hydroxynortriptyline-d₃ is a deuterium labeled (E)-10-Hydroxy Nortriptyline. (E)-10-Hydroxy Nortriptyline is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].

HY-153845

RNA Aptamer Broccoli sodium	Others	Others
RNA Aptamer Broccoli (sodium) is a 49-nt-long aptamer that is substantially shorter than Spinach and Spinach2 and exhibits bright green fluorescence upon binding DFHBI or DFHBI-1T (soluble analogs of the fluorophore of green fluorescent protein). RNA Aptamer Broccoli (sodium) can be used to visualize RNA expression or localization in live cells. In vitro Broccoli exhibits a similar high folding efficiency as Spinach2, but exhibits markedly lower dependence on magnesium for folding and increased thermostability. Additionally, unlike Spinach2, Broccoli does not require the use of a tRNA scaffold to promote its folding in vivo.

Neurotransmitter Receptor Compound Library	1785 compounds
Neurotransmitter (NT) receptors, also known as neuroreceptors, are a broadly diverse group of membrane proteins that bind neurotransmitters for neuronal signaling. There are two major types of neurotransmitter receptors: ionotropic and metabotropic. Ionotropic receptors are ligand-gated ion channels, meaning that the receptor protein includes both a neurotransmitter binding site and an ion channel. The binding of a neurotransmitter molecule (the ligand) to the binding site induces a conformational change in the receptor structure, which opens, or gates, the ion channel. The term “metabotropic receptors” is typically used to refer to transmembrane G-protein-coupled receptors. Metabotropic receptors trigger second messenger-mediated effects within cells after neurotransmitter binding. In some neurological diseases, the neurotransmitter receptor itself appears to be the target of the disease process. Many neuroactive drugs act by modifying neurotransmitter receptors. A better understanding of neurotransmitter receptor changes in disease may lead to improvements in therapy. MCE designs a unique collection of 1785 compounds targeting a variety of neurotransmitter receptors. MCE Neurotransmitter Receptor Compound Library is a useful tool for neurological diseases drug discovery.

NT1-014B	Drug Delivery
NT1-014B is a potent NT1-lipidoid encapsulated AmB (amphotericin B). NT1-014B dopes the NT-lipidoids into BBB-impermeable lipid nanoparticles (LNPs) gave the LNPs the ability to cross the BBB. NT1-014B enhances brain delivery through intravenous injection .

NT1-O12B	Drug Delivery
NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .

Neurotensin(8-13) 1 Publications Verification	Neurotensin Receptor	Neurological Disease
Neurotensin (8-13) is an active fragment of Neurotensin. Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.

NT 13 TPPT	iGluR	Neurological Disease
NT 13 (TPPT) is a tetrapeptide having the amino acid sequence L-threonyl-L-prolyl-L-prolyl-L-threonine amide. NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.

vMIP-II (1-21) NT21MP; V1 peptide	CXCR	Inflammation/Immunology Cancer
vMIP-II (1-21) is a CXCR4 antagonist. vMIP-II has broad-spectrum interaction with CC and CXC chemokine receptors. vMIP-II (1-21) binds with CXCR4 with an IC₅₀ value of 190 nM for competing with CXCR4 binding of 125I-SDF-1R .

[D-Trp11]-Neurotensin	Neurotensin Receptor	Neurological Disease
[D-Trp11]-Neurotensin, an analogue of Neurotensin (NT), is a selective antagonist of NT in perfused rat hearts but behaves as a full agonist in guinea pig atria and rat stomach strips. [D-Trp11]-Neurotensin can inhibit NT-induced hypotension .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-137499

NT1-O12B	Structural Classification Alkaloids Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Indole Alkaloids	Liposome Endogenous Metabolite
NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .

Species:	Human (23) Mouse (6) Rat (4) Cynomolgus (2) Canine (2)
Tag:	His (26) Tag Free (4) Avi (1) GST (1) Fc (7) Flag (2)
Source:	HEK293 (28) P. pastoris (1) Sf9 insect cells (1) E. coli (7)

Cat. No.	Compare	Product Name	Species	Source

HY-P7273

	NT-4 Protein, Mouse rMuNT-4; NT-5; NTF4; NTF5	Mouse	E. coli
	NT-4 Protein, Mouse is a member of neurotrophins family, binding with two distinct receptors: TrkB, high affinity receptor and p75 low-affinity neurotrophin receptor (p75NTR).

HY-P7272

	Neurotrophin-4 Protein, Human rHuNT-4; NT-5; NTF4; NTF5; NT4	Human	E. coli
	NT-4 Protein, Human is a member of neurotrophins family, binding with two distinct receptors: TrkB, high affinity receptor and p75 low-affinity neurotrophin receptor (p75NTR).

HY-P701335

	Neurotrophin-4 Protein, Human (His) rHuNT-4; NT-5; NTF4; NTF5; NT4	Human	E. coli
	Neurotrophin-4 (NT-4) protein serves as a vital target-derived survival factor for peripheral sensory sympathetic neurons, emphasizing its crucial role in promoting their survival and maintenance. The specific and targeted actions of NT-4 underscore its significance as a neurotrophic factor in the intricate mechanisms governing the well-being of peripheral neurons within the sympathetic nervous system. Neurotrophin-4 Protein, Human (His) is the recombinant human-derived Neurotrophin-4 protein, expressed by E. coli , with N-6*His labeled tag. The total length of Neurotrophin-4 Protein, Human (His) is 129 a.a., with molecular weight of 19 kDa.

HY-P77534

	CD73/5'-Nucleotidase Protein, Human (Biotinylated, HEK293, His-Avi) 5-NT; 5'-Nucleotidase; CD73; E5NT; NT5E; NTE	Human	HEK293
	CD73/5'-Nucleotidase Protein hydrolyzes nucleotide monophosphates, favoring AMP as the primary substrate and showing a preference for ribonucleotide monophosphates. It releases inorganic phosphate and the corresponding nucleoside. CD73 also acts on other substrates, including IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD, and NMN. CD73/5'-Nucleotidase Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived CD73/5'-Nucleotidase protein, expressed by HEK293 , with C-His labeled tag. The total length of CD73/5'-Nucleotidase Protein, Human (Biotinylated, HEK293, His) is 521 a.a., with molecular weight of ~59.2 KDa.

HY-P74272

	CD73/5'-Nucleotidase Protein, Human (T376A, HEK293, Fc) 5-NT; 5'-Nucleotidase; CD73; E5NT; NT5E; NTE	Human	HEK293
	CD73/5'-Nucleotidase Protein hydrolyzes nucleotide monophosphates, favoring AMP as the primary substrate and showing a preference for ribonucleotide monophosphates. It releases inorganic phosphate and the corresponding nucleoside. CD73 also acts on other substrates, including IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD, and NMN. CD73/5'-Nucleotidase Protein, Human (T376A, HEK293, Fc) is the recombinant human-derived CD73/5'-Nucleotidase protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD73/5'-Nucleotidase Protein, Human (T376A, HEK293, Fc) is 547 a.a., with molecular weight of ~84.5 kDa.

HY-P77455

	NT5C3A/NT5C3 Protein, Human Cytosolic 5'-nucleotidase 3A; NT5C3; P5N1; UMPH1	Human	E. coli
	NT5C3A/NT5C3 Protein, a nucleotidase, preferentially hydrolyzes cytidine monophosphate (CMP) and 7-methylguanosine monophosphate (m(7)GMP), emphasizing a potential role in cellular processes, with a preference for CMP. NT5C3A/NT5C3 Protein, Human is the recombinant human-derived NT5C3A/NT5C3 protein, expressed by E. coli , with tag free. The total length of NT5C3A/NT5C3 Protein, Human is 286 a.a., with molecular weight of ~32 kDa.

HY-P70492

	CD73/5'-Nucleotidase Protein, Human (T376A, M379T, HEK293, His) 5'-Nucleotidase; 5'-NT; Ecto-5'-Nucleotidase; CD73; NT5E; NT5; NTE	Human	HEK293
	CD73/5'-Nucleotidase Protein hydrolyzes nucleotide monophosphates, favoring AMP as the primary substrate and showing a preference for ribonucleotide monophosphates. It releases inorganic phosphate and the corresponding nucleoside. CD73 also acts on other substrates, including IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD, and NMN. CD73/5'-Nucleotidase Protein, Human (T376A, M379T, HEK293, His) is the recombinant human-derived CD73/5'-Nucleotidase protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD73/5'-Nucleotidase Protein, Human (T376A, M379T, HEK293, His) is 521 a.a., with molecular weight of ~62.0 kDa.

HY-P7836

	CD73/5'-Nucleotidase Protein, Cynomolgus (521a.a, HEK293, His) rCynEcto-5'-nucleotidase/CD73, His; 5'-Nucleotidase; 5'-NT; Ecto-5'-Nucleotidase; CD73; NT5E; NT5; NTE	Cynomolgus	HEK293
	CD73/5'-Nucleotidase Protein, Cynomolgus (HEK 293, His) is a CD73 protein with a His-flag. CD73/5'-Nucleotidase Protein a zinc-dependent, 70 kDa homodimeric enzyme that binds to the cell membrane through a glycosyl phophatidylinositol (GPI) anchor.

HY-P70010

	CD73/5'-Nucleotidase Protein, Human (521a.a, HEK293, His) rHu5'-nucleotidase/CD73, His; 5'-Nucleotidase; 5'-NT; Ecto-5'-Nucleotidase; CD73; NT5E; NT5; NTE	Human	HEK293
	CD73/5'-Nucleotidase Protein hydrolyzes nucleotide monophosphates, favoring AMP as the primary substrate and showing a preference for ribonucleotide monophosphates. It releases inorganic phosphate and the corresponding nucleoside. CD73 also acts on other substrates, including IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD, and NMN. CD73/5'-Nucleotidase Protein, Human (521a.a, HEK293, His) is the recombinant human-derived CD73/5'-Nucleotidase protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD73/5'-Nucleotidase Protein, Human (521a.a, HEK293, His) is 521 a.a., with molecular weight of ~62.0 kDa.

HY-P77817

	NTS1/NTSR1 Protein, Mouse (HEK293, Fc) NT; NTR; NTR1; NTRH; NTRR; NTS1; NTSR1; NMN-125; NN; NT/N	Mouse	HEK293
	NTS1/NTSR1, the neurotensin receptor 1, potentially regulates fat metabolism through endocrine or paracrine mechanisms. Interacting with its ligand, neurotensin, NTS1/NTSR1 induces smooth muscle contraction. The receptor's interactions with neurotensin and other proteins like SORT1 and SORL1 suggest involvement in diverse cellular processes, indicating potential implications for fat metabolism regulation. NTS1/NTSR1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived NTS1/NTSR1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of NTS1/NTSR1 Protein, Mouse (HEK293, Fc) is 140 a.a., with molecular weight of 48-53 kDa.

HY-P701029

	NTS1/NTSR1 Protein, Cynomolgus (HEK293, His) NT; NTR; NTR1; NTRH; NTRR; NTS1; NTSR1; NMN-125; NN; NT/N; NTS	Cynomolgus	HEK293
	NTS1/NTSR1 protein, as the receptor for neurotensin, regulates fat metabolism through potential endocrine and paracrine functions. The neuropeptide exerts influence on smooth muscle contraction. NTS1/NTSR1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived NTS1/NTSR1 protein, expressed by HEK293 , with C-His labeled tag. The total length of NTS1/NTSR1 Protein, Cynomolgus (HEK293, His) is 140 a.a., with molecular weight of 20-25 kDa.

HY-P74702

	Neurotrimin Protein, Human (HEK293, Fc) Neurotrimin; hNT; NTM; IGLON2; NT	Human	HEK293
	Neurotrimin Protein, a neural cell adhesion molecule, plays a crucial role in facilitating neural connections through its adhesive properties. As a member of the cell adhesion molecule family, Neurotrimin influences various aspects of neural function, including cell adhesion, communication, and potential contributions to neuronal development and synaptic plasticity, underscoring its significance as a molecular mediator within the nervous system. Neurotrimin Protein, Human (HEK293, Fc) is the recombinant human-derived Neurotrimin protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Neurotrimin Protein, Human (HEK293, Fc) is 312 a.a., with molecular weight of ~57.6 kDa.

HY-P73465

	TrkC Protein, Human (HEK293, His) TrkC; NT-3 Growth Factor Receptor; NTRK3; TRKC	Human	HEK293
	TrkC Protein, a receptor tyrosine kinase, crucially contributes to nervous system and potential heart development. Upon NTF3/neurotrophin-3 binding, TrkC undergoes autophosphorylation, activating pathways like phosphatidylinositol 3-kinase/AKT and MAPK. These pathways regulate cell survival and differentiation, emphasizing TrkC's pivotal role in essential cellular processes during development. TrkC Protein, Human (HEK293, His) is the recombinant human-derived TrkC protein, expressed by HEK293 , with C-His labeled tag. The total length of TrkC Protein, Human (HEK293, His) is 428 a.a., with molecular weight of 80-90 kDa.

HY-P74701

	Neurotrimin Protein, Human (312a.a, HEK293, His) Neurotrimin; hNT; NTM; IGLON2; NT	Human	HEK293
	Neurotrimin Protein, a neural cell adhesion molecule, plays a crucial role in facilitating neural connections through its adhesive properties. As a member of the cell adhesion molecule family, Neurotrimin influences various aspects of neural function, including cell adhesion, communication, and potential contributions to neuronal development and synaptic plasticity, underscoring its significance as a molecular mediator within the nervous system. Neurotrimin Protein, Human (312a.a, HEK293, His) is the recombinant human-derived Neurotrimin protein, expressed by HEK293 , with C-His labeled tag. The total length of Neurotrimin Protein, Human (312a.a, HEK293, His) is 312 a.a., with molecular weight of ~32.3 kDa.

HY-P73464

	TrkC Protein, Human (HEK293, His-Fc) TrkC; NT-3 Growth Factor Receptor; NTRK3; TRKC	Human	HEK293
	TrkC Protein, a receptor tyrosine kinase, crucially contributes to nervous system and potential heart development. Upon NTF3/neurotrophin-3 binding, TrkC undergoes autophosphorylation, activating pathways like phosphatidylinositol 3-kinase/AKT and MAPK. These pathways regulate cell survival and differentiation, emphasizing TrkC's pivotal role in essential cellular processes during development. TrkC Protein, Human (HEK293, His-Fc) is the recombinant human-derived TrkC protein, expressed by HEK293 , with C-hFc, C-His labeled tag. The total length of TrkC Protein, Human (HEK293, His-Fc) is 428 a.a., with molecular weight of 110-120 kDa.

HY-P73461

	TrkB Protein, Canine (HEK293, His) BDNF/NT-3 Growth Factors Receptor; Trk-B; NTRK2; TRKB	Canine	HEK293
	TrkB Protein is a neurotrophic factor receptor and a member of the tropomyosin receptor kinase family. TrkB Protein has high affinity for brain-derived neurotrophic factor (BDNF) and plays a role in various physiological functions of neurons, including cell survival and differentiation. TrkB Protein has carcinogenic activity. TrkB Protein, Canine (HEK293, His) is the recombinant canine-derived TrkB protein, expressed by HEK293 , with C-His labeled tag. The total length of TrkB Protein, Canine (HEK293, His) is 399 a.a., with molecular weight of ~60-78 kDa.

HY-P73574

	TrkB Protein, Rat (HEK293, His) BDNF/NT-3 Growth Factors Receptor; Trk-B; NTRK2; TRKB	Rat	HEK293
	TrkB is a key receptor tyrosine kinase that coordinates multiple neuronal processes in the central and peripheral nervous systems. As a receptor for BDNF and NTF4, it regulates survival through NTF3. TrkB Protein, Rat (HEK293, His) is the recombinant rat-derived TrkB protein, expressed by HEK293 , with C-His labeled tag. The total length of TrkB Protein, Rat (HEK293, His) is 398 a.a., with molecular weight of ~67 kDa.

HY-P73575

	TrkB Protein, Rat (HEK293, Fc) BDNF/NT-3 Growth Factors Receptor; Trk-B; NTRK2; TRKB	Rat	HEK293
	TrkB is a key receptor tyrosine kinase that coordinates multiple neuronal processes in the central and peripheral nervous systems. As a receptor for BDNF and NTF4, it regulates survival through NTF3. TrkB Protein, Rat (HEK293, Fc) is the recombinant rat-derived TrkB protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TrkB Protein, Rat (HEK293, Fc) is 429 a.a., with molecular weight of ~120 kDa.

HY-P73576

	TrkB Protein, Canine (HEK293, Fc) BDNF/NT-3 Growth Factors Receptor; Trk-B; NTRK2; TRKB	Canine	HEK293
	TrkB Protein is a neurotrophic factor receptor and a member of the tropomyosin receptor kinase family. TrkB Protein has high affinity for brain-derived neurotrophic factor (BDNF) and plays a role in various physiological functions of neurons, including cell survival and differentiation. TrkB Protein has carcinogenic activity. TrkB Protein, Canine (HEK293, Fc) is the recombinant canine-derived TrkB protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TrkB Protein, Canine (HEK293, Fc) is 430 a.a., with molecular weight of ~71.2 kDa.

HY-P78773

	Sortilin/SORT1 Protein, Human (HEK293, His) Sortilin; SORT1; 100 kDa NT receptor; Glycoprotein 95; Gp95; Gp95LDLCQ6; Neurotensin receptor 3; NT3NTR3; NTr3; sortilin 1;	Human	HEK293
	Sortilin/SORT1 Protein serves as a sorting receptor in the Golgi and a clearance receptor on the cell surface. It plays a crucial role in protein transport to lysosomes, independent of M6PR. Lysosomal proteins bind to the Golgi receptor, forming a complex transported to an acidic prelysosomal compartment. The low pH mediates dissociation, and the receptor recycles via retromer. Sortilin is involved in Golgi-to-endosome protein transport, facilitates neuronal apoptosis, acts as a neurotensin receptor, and aids insulin responsiveness in adipocytes. It interacts with partners like LRPAP1/RAP, GM2A, NTS, and NGFR, as well as adapter proteins GGA1 and GGA2, and proteins CLN5, PSAP, GRN, and SMPD1, contributing to diverse cellular functions. Sortilin/SORT1 Protein, Human (HEK293, His) is the recombinant human-derived Sortilin/SORT1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Sortilin/SORT1 Protein, Human (HEK293, His) is 678 a.a., with molecular weight of 90-110 kDa.

HY-P73462

	TrkB Protein, Human (HEK293, His-Fc) BDNF/NT-3 Growth Factors Receptor; Trk-B; NTRK2; TRKB	Human	HEK293
	The TrkB protein is a key receptor tyrosine kinase that plays a key role in central and peripheral nervous system development. It regulates neuronal survival, proliferation, migration, differentiation, synapse formation, and plasticity. TrkB Protein, Human (HEK293, His-Fc) is the recombinant human-derived TrkB protein, expressed by HEK293 , with C-hFc, C-His, C-10*His labeled tag. The total length of TrkB Protein, Human (HEK293, His-Fc) is 399 a.a., with molecular weight of 95-130 kDa.

HY-P73574A

	TrkB Protein, Rat (HEK293, C-His) BDNF/NT-3 Growth Factors Receptor; Trk-B; NTRK2; TRKB	Rat	HEK293
	TrkB, a pivotal receptor tyrosine kinase, orchestrates diverse neuronal processes in the central and peripheral nervous systems. Serving as a receptor for BDNF and NTF4, it modulates survival through NTF3. Upon ligand binding, TrkB undergoes activation, initiating downstream cascades. It recruits effectors like SHC1, FRS2, SH2B1, SH2B2, and PLCG1, regulating pathways for differentiation, growth, survival, and synaptic plasticity. TrkB's role in learning involves short-term synaptic function, long-term potentiation, and PLCG1-mediated suppression of anoikis. Additionally, it contributes to neurotrophin-dependent calcium signaling in glial cells. TrkB Protein, Rat (HEK293, C-His) is the recombinant rat-derived TrkB protein, expressed by HEK293, with C-6*His labeled tag. The total length of TrkB Protein, Rat (HEK293, C-His) is 398 a.a., with molecular weight of ~62-85 kDa.

HY-P7448

	CD73/5'-Nucleotidase Protein, Mouse (HEK293, His) rMuCD73, His; 5'-Nucleotidase; NT5E; CD-73	Mouse	HEK293
	CD73/5'-Nucleotidase Protein Protein, Mouse (HEK293, His) is a recombinant mouse CD73 expressed by HEK293 cells with His tag. CD73 is a cell surface enzyme that catalyzes the dephosphorylation of extracellular AMP to adenosine.

HY-P7449

	CD73/5'-Nucleotidase Protein, Rat (HEK293, His) rRtCD73, His; 5'-Nucleotidase; NT5E; CD-73	Rat	HEK293
	CD73/5'-Nucleotidase Protein, Rat (HEK293, His) is a 70-90 kDa rat CD73 protein with His-flag expressed by HEK293. Rat CD73 is a cell membrane protein that catalyzes the conversion of purine and pyrimidine ribo- and deoxyribonucleoside monophosphates to the corresponding nucleosides.

HY-P71120

	NPPB Protein, Human (76a.a, Flag-His) Natriuretic peptides B; Gamma-brain natriuretic peptide; NPPB; BNP; NT-proBNP	Human	E. coli
	NPPB proteins are members of the natriuretic peptide family and are key regulators of cardiovascular homeostasis. As a hormone, NPPB is produced and released primarily by ventricular myocytes in response to increases in pressure and volume. NPPB Protein, Human (76a.a, Flag-His) is the recombinant human-derived NPPB protein, expressed by E. coli , with N-6*His, N-Flag labeled tag. The total length of NPPB Protein, Human (76a.a, Flag-His) is 76 a.a., with molecular weight of ~14.0 kDa.

HY-P73463

	TrkB Protein, Mouse (429a.a, HEK293, His) BDNF/NT-3 Growth Factors Receptor; Trk-B; NTRK2; TRKB	Mouse	HEK293
	TrkB protein, also known as tropomyosin receptor kinase B, consists of a non-catalytic isoform. Unlike its catalytic isoform, the noncatalytic isoform of TrkB lacks intrinsic kinase activity. TrkB Protein, Mouse (429a.a, HEK293, His) is the recombinant mouse-derived TrkB protein, expressed by HEK293 , with C-His labeled tag. The total length of TrkB Protein, Mouse (429a.a, HEK293, His) is 429 a.a., with molecular weight of 75-85 kDa.

HY-P70456

	Neurotrophin-3 Protein, Human Neurotrophin-3; NT-3; HDNF; Nerve Growth Factor 2; NGF-2; Neurotrophic Factor; NTF3	Human	E. coli
	Neurotrophin-3 Protein, Human is a recombinant Neurotrophin-3 protein expressed in E. coli system. Neurotrophin-3 is widely expressed in the nervous system. Neurotrophin-3 reduces cellular damage, improves neuronal regeneration in different models of lesions.

HY-P71849

	NT5C1A Protein, Human (P.pastoris, His) 5' nucleotidase cytosolic IA; CN IA; Cytosolic 5' nucleotidase 1A; cytosolic; IA	Human	P. pastoris
	The NT5C1A protein plays a key role in cellular nucleotide metabolism, catalyzing the hydrolysis of ribonucleotide and deoxyribonucleotide monophosphates and releasing inorganic phosphates and the corresponding nucleosides. Although AMP was identified as the primary substrate of NT5C1A, this versatile enzyme is also capable of hydrolyzing other nucleotides, such as dCMP and IMP. NT5C1A Protein, Human (P.pastoris, His) is the recombinant human-derived NT5C1A protein, expressed by P. pastoris , with N-His labeled tag. The total length of NT5C1A Protein, Human (P.pastoris, His) is 368 a.a., with molecular weight of ~43.0 kDa.

HY-P71386

	TrkC Protein, Mouse (HEK293, His) GP145-TrkC; TrkC; trk-C; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase; NT-3 Growth Factor Receptor	Mouse	HEK293
	TrkC Protein, a receptor tyrosine kinase, is vital in nervous system and potential heart development. Upon binding its ligand NTF3/neurotrophin-3, TrkC undergoes autophosphorylation, activating key signaling pathways like phosphatidylinositol 3-kinase/AKT and MAPK. These pathways intricately govern cell survival and differentiation, underscoring TrkC's pivotal role in orchestrating fundamental processes during development. TrkC Protein, Mouse (HEK293, His) is the recombinant mouse-derived TrkC protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TrkC Protein, Mouse (HEK293, His) is 398 a.a., with molecular weight of 80-110 kDa.

HY-P71174

	NTAQ1 Protein, Human (GST) Protein N-terminal glutamine amidohydrolase; WDYHV1; Protein NH2-terminal glutamine deamidase; N-terminal Gln amidase; NT(Q)-amidase; C8orf32; NTAQ1	Human	E. coli
	NTAQ1 Protein is a monomeric globular protein with alpha-beta-alpha three-layer sandwich architecture. NTAQ1 converts N-terminal glutamine to glutamate by eliminating the amine group and plays an essential role in the N-end rule pathway for protein degradation. The active site and catalytic mechanism of NTAQ1 are similar to those of transglutaminases. NTAQ1 Protein, Human (GST) is the recombinant human-derived NTAQ1 protein, expressed by E. coli , with N-GST labeled tag. The total length of NTAQ1 Protein, Human (GST) is 205 a.a., with molecular weight of 45-50 kDa.

HY-P72436

	TrkB Protein, Mouse (398a.a, HEK293, His) BDNF/NT-3 Growth Factors Receptor; GP145-TrkB; Trk-B; Neurotrophic Tyrosine Kinase Receptor Type 2; TrkB Tyrosine Kinase; NTRK2; TRKB	Mouse	HEK293
	TrkB protein, also known as tropomyosin receptor kinase B, consists of a non-catalytic isoform. Unlike its catalytic isoform, the noncatalytic isoform of TrkB lacks intrinsic kinase activity. TrkB Protein, Mouse (398a.a, HEK293, His) is the recombinant mouse-derived TrkB protein, expressed by HEK293 , with C-His labeled tag. The total length of TrkB Protein, Mouse (398a.a, HEK293, His) is 398 a.a., with molecular weight of 60-90 kDa.

HY-P70793

	TrkB Protein, Human (HEK293, His) BDNF/NT-3 Growth Factors Receptor; GP145-TrkB; Trk-B; Neurotrophic Tyrosine Kinase Receptor Type 2; TrkB Tyrosine Kinase; Tropomyosin-Related Kinase B; NTRK2; TRKB	Human	HEK293
	The TrkB protein is a key receptor tyrosine kinase that plays a key role in central and peripheral nervous system development. It regulates neuronal survival, proliferation, migration, differentiation, synapse formation, and plasticity. TrkB Protein, Human (HEK293, His) is the recombinant human-derived TrkB protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TrkB Protein, Human (HEK293, His) is 399 a.a., with molecular weight of 60-105 kDa.

HY-P702763

	NTRK2/TrkB Protein, Human (Biotinylated, sf9, Flag) NTRK2; neurotrophic tyrosine kinase, receptor, type 2; BDNF/NT-3 growth factors receptor; trk-B; GP145-TrkB/GP95-TrkB; trkB tyrosine kinase; Neural receptor protein-tyrosine kinase (trkB); Tkrb; trkB; TRKB1; RATTRKB1	Human	Sf9 insect cells

HY-P70410

	MGAT2 Protein, Human (HEK293, His) rHuAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase/MGAT2, His ; Alpha-1; 6-Mannosyl-Glycoprotein 2-Beta-N-Acetylglucosaminyltransferase; Beta-1; 2-N-acetylglucosaminyltransferase II; GlcNAc-T II; NT-II; Mannoside Acetylglucosaminyltransferase 2; N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase II; MGAT2	Human	HEK293
	The MGAT2 protein plays an important role in protein N-glycosylation, catalyzing the transfer of GlcNAc to the free terminal mannose in nascent N-linked glycan chains. This forms a second branch of the complex glycan and is critical for glycoprotein maturation and functional diversity. MGAT2 Protein, Human (HEK293, His) is the recombinant human-derived MGAT2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of MGAT2 Protein, Human (HEK293, His) is 418 a.a., with molecular weight of ~50.0 kDa.

HY-P7817A

	Prostatic acid phosphatase/ACPP Protein, Human (HEK293, His) Prostatic Acid Phosphatase; PAP; 5'-Nucleotidase; 5'-NT, Ecto-5'-Nucleotidase; Thiamine Monophosphatase; TMPase; ACPP	Human	HEK293
	Acid prostatic phosphatase (ACPP) is an enzyme that catalyzes the conversion of orthophosphate monoesters into alcohol and orthophosphate. ACPP is regulated by androgens and secreted by prostate epithelial cells. Prostatic acid phosphatase/ACPP Protein, Human (HEK293, His) is the recombinant human-derived Prostatic acid phosphatase/ACPP protein, expressed by HEK293 , with C-His labeled tag. The total length of Prostatic acid phosphatase/ACPP Protein, Human (HEK293, His) is 350 a.a., with molecular weight of 43-55 kDa.

HY-P75796

	GPR56 Protein, Human (HEK293, His) Adhesion G-protein coupled receptor G1; ADGRG1 NT; ADGRG1; GPR56; TM7LN4; TM7XN1	Human	HEK293
	GPR56, a cell adhesion receptor, mediates cell-matrix adhesion in developing neurons and hematopoietic stem cells. It acts as a receptor for collagen III (COL3A1), influencing cortical development and hematopoietic stem cell maintenance. Additionally, GPR56 plays a pivotal role in cancer progression by inhibiting angiogenesis via PRKCA-mediated signaling and is essential for testis development. GPR56 Protein, Human (HEK293, His) is the recombinant human-derived GPR56 protein, expressed by HEK293, with C-His labeled tag. The total length of GPR56 Protein, Human (HEK293, His) is 317 a.a., with molecular weight of 45-70 kDa.

HY-P7817

	Prostatic acid phosphatase/ACPP Protein, Human (354a.a, HEK293, His, solution) rHuProstatic acid phosphatase/ACPP, His; Prostatic Acid Phosphatase; PAP; 5'-Nucleotidase; 5'-NT, Ecto-5'-Nucleotidase; Thiamine Monophosphatase; TMPase; ACPP	Human	HEK293
	PPAP protein, a nonspecific tyrosine phosphatase, has anticancer and antiproliferative activities. The PPAP protein dephosphorylates a variety of substrates under acidic conditions (pH 4-6), resulting in the inactivation of lysophosphatidic acid in seminal plasma. The PPAP protein is also a common biomarker for prostate cancer and can inhibit tumor development. Prostatic acid phosphatase/ACPP Protein, Human (354a.a, HEK293, His, solution) is the recombinant human-derived Prostatic acid phosphatase/ACPP protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Prostatic acid phosphatase/ACPP Protein, Human (354a.a, HEK293, His, solution) is 354 a.a., with molecular weight of ~50.0 kDa.

Cat. No.	Product Name	Chemical Structure