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Results for "

Nef-dependent

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-125028
    Hck-IN-1

    		Src HIV Infection
    Hck-IN-1 (compound B9), a diphenylpyrazolo compound, is a selective Nef-dependent Hck inhibitor with IC50s of 2.8 μM, >20 μM for Nef:Hck complex and Hck, respectively. Hck-IN-1 is a direct and wide HIV-1 Nef antagonists with an IC50 of 100-300 nM for wild-type HIV-1 replication. Hck-IN-1 binds pocket residue Asn126 and has anti-retroviral activity .
    Hck-IN-1
  • HY-121718
    DQBS

    		HIV Infection
    DQBS can bind to HIV-1 nef protein, and inhibits Nef-dependent HIV replication .
    DQBS

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