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Results for "

Niemann-Pick

" in MedChemExpress (MCE) Product Catalog:

13

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4

Recombinant Proteins

2

Isotope-Labeled Compounds

3

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  • HY-P74695
    Niemann Pick C1/NPC1 Protein, Human (His)

    NPC intracellular cholesterol transporter 1; Niemann-Pick C1 protein; NPC1

    		 Human HEK293
    The Niemann Pick C1/NPC1 protein is an intracellular cholesterol transporter that cooperates with NPC2 to promote cholesterol efflux from the endosomal/lysosomal compartment. NPC2 transfers unesterified cholesterol to the N-terminal domain of NPC1, where the cholesterol is bound in a hydrophobic pocket. Niemann Pick C1/NPC1 Protein, Human (His-Flag) is the recombinant human-derived Niemann Pick C1/NPC1 protein, expressed by HEK293 , with N-His labeled tag. The total length of Niemann Pick C1/NPC1 Protein, Human (His-Flag) is 251 a.a., with molecular weight of ~38-55 kDa.
  • HY-P74692
    Niemann Pick C2/NPC2 Protein, Rat (HEK293, His)

    NPC intracellular cholesterol transporter 2; Niemann-Pick disease type C2 protein; HE1

    		 Rat HEK293
    Niemann-Pick C2/NPC2 protein is an important member of the NPC2 family and plays an important role in lipid metabolism and transport, helping to regulate intracellular cholesterol homeostasis and lipid transport. Its involvement in cellular processes highlights its importance in maintaining lipid homeostasis. Niemann Pick C2/NPC2 Protein, Rat (HEK293, His) is the recombinant rat-derived Niemann Pick C2/NPC2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Niemann Pick C2/NPC2 Protein, Rat (HEK293, His) is 130 a.a., with molecular weight of ~15.9 kDa.
  • HY-P74693
    Niemann Pick C2/NPC2 Protein, Mouse (HEK293, His)

    NPC intracellular cholesterol transporter 2; Niemann-Pick disease type C2 protein; HE1

    		 Mouse HEK293
    Niemann Pick C2/NPC2 Protein, a lysosomal protein, plays a critical role in cholesterol trafficking and lipid metabolism. It facilitates the transport of cholesterol from lysosomes to other cellular compartments. Understanding the functions of NPC2 Protein is vital for studying lipid disorders and developing therapeutic strategies targeting abnormal cholesterol metabolism. Niemann Pick C2/NPC2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Niemann Pick C2/NPC2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Niemann Pick C2/NPC2 Protein, Mouse (HEK293, His) is 130 a.a., with molecular weight of ~15.9-19 kDa.
  • HY-P74694
    Niemann Pick C2/NPC2 Protein, Human (HEK293, His)

    NPC intracellular cholesterol transporter 2; Niemann-Pick disease type C2 protein; HE1

    		 Human HEK293
    The Niemann Pick C2/NPC2 Protein is a crucial lysosomal protein that regulates cholesterol trafficking and lipid metabolism. It enables the movement of cholesterol from lysosomes to other parts of the cell. Studying the functions of NPC2 Protein is essential for understanding lipid disorders and developing treatments targeting disrupted cholesterol metabolism. Niemann Pick C2/NPC2 Protein, Human (HEK293, His) is the recombinant human-derived Niemann Pick C2/NPC2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Niemann Pick C2/NPC2 Protein, Human (HEK293, His) is 132 a.a., with molecular weight of 21-24 kDa & 27-35 kDa, respectively.

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