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Results for "

OA

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Autophagy (1) Biochemical Assay Reagents (1) Calcium Channel (3) Cathepsin (1) Cholinesterase (ChE) (1) COX (1) DNA/RNA Synthesis (4) Endogenous Metabolite (1) Glucosidase (2) Isotope-Labeled Compounds (1) MMP (7) NF-κB (1) P2Y Receptor (1) Parasite (3) PGE synthase (1) Sodium Channel (3) TGF-beta/Smad (4) Wnt (1)
By Research Areas:	Cancer (8) Cardiovascular Disease (5) Infection (3) Inflammation/Immunology (21) Metabolic Disease (4) Neurological Disease (2)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-121936

Yohimbic acid	Others	Cardiovascular Disease Inflammation/Immunology
Yohimbic acid is an amphoteric demethylated derivative of Yohimbine. Yohimbic acid exhibits vasodilatory action. Yohimbic acid also can be used for the research of osteoarthritis (OA) .

HY-121936A

Yohimbic acid hydrate	Others	Cardiovascular Disease Inflammation/Immunology
Yohimbic acid hydrate is an amphoteric demethylated derivative of Yohimbine (HY-12715). Yohimbic acid hydrate exhibits vasodilatory action. Yohimbic acid hydrate also can be used for the research of osteoarthritis (OA) .

HY-B2082

Fursultiamine	Others	Neurological Disease Inflammation/Immunology Cancer
Fursultiamine is a vitamin B₁ derivative, has anti-nociceptive and antineoplastic activity. Fursultiamine can be used for vitamin B₁ deficiency, osteoarthritis (OA) and cancer research .

HY-N0665

Specnuezhenide 1 Publications Verification (8E)-Nuezhenide	NF-κB Wnt	Inflammation/Immunology
Specnuezhenide ((8E)-Nuezhenide) is isolated from the fruits of Ligustrum lucidum. Specnuezhenide ((8E)-Nuezhenide) can inhibit IL-1β-induced inflammation in chondrocytes via inhibition of NF-κB and wnt/β-catenin signaling. Specnuezhenide ((8E)-Nuezhenide) exerts anti-inflammatory effects in a rat model of osteoarthritis (OA) .

HY-P2414

MMP-13 Substrate

MMP Inflammation/Immunology

MMP-13 Substrate is a substrate of MMP-13. MMP-13 Substrate can be used for the research of osteoarthritis (OA) .

MMP-13 Substrate	MMP	Inflammation/Immunology
MMP-13 Substrate is a substrate of MMP-13. MMP-13 Substrate can be used for the research of osteoarthritis (OA) .

HY-16268

Kartogenin Maximum Cited Publications 20 Publications Verification KGN	TGF-beta/Smad	Inflammation/Immunology
Kartogenin (KGN) is an inducer of differentiation of human mesenchymal stem cells into chondrocytes, with an EC₅₀ of 100 nM. Kartogenin binds filamin A, disrupts its interaction with the transcription factor core-binding factor β subunit (CBFβ), and induces chondrogenesis by regulating the CBFβ-RUNX1 transcriptional program. Kartogenin can be used for the research of osteoarthritis (OA) .

HY-N0866

20-Deoxyingenol 1 Publications Verification	Autophagy	Inflammation/Immunology
20-Deoxyingenol, a diterpene, is isolated from the roots of Euphorbia kansui. 20-Deoxyingenol can promote autophagy and lysosomal biogenesis by promoting the nuclear translocation of transcription factor EB (TFEB) in vitro. 20-Deoxyingenol can be used for the research of osteoarthritis (OA) .

HY-112546

MMP-2 Inhibitor I

MMP Cancer

MMP-2 Inhibitor I (OA-Hy) is a potent MMP-2 inhibitor with a K_i of 1.7 μM .
HY-146981

α-Glucosidase-IN-3

Glucosidase Inflammation/Immunology

α-Glucosidase-IN-3 is an oleanolic acid (OA) oxime ester derivativ eagainst α-glucosidase(IC₅₀=0.35 µM) and α-amylase.

MMP-2 Inhibitor I	MMP	Cancer
MMP-2 Inhibitor I (OA-Hy) is a potent MMP-2 inhibitor with a K_i of 1.7 μM .

α-Glucosidase-IN-3	Glucosidase	Inflammation/Immunology
α-Glucosidase-IN-3 is an oleanolic acid (OA) oxime ester derivativ eagainst α-glucosidase(IC₅₀=0.35 µM) and α-amylase.

HY-129467

(Rac)-Idroxioleic acid 2-Hydroxyoleic acid; 2-OHOA	Apoptosis	Cancer
(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a synthetic oleic acid (OA) derivative that binds to the plasma membrane and alters lipid organization. (Rac)-Idroxioleic acid has anti-tumor effect .

HY-149377

MMP13-IN-4

MMP Metabolic Disease

MMP13-IN-4 (compound 13) is a potent and selective inhibitor of MMP-13 (IC₅₀=14.6 μM)，involved in osteoarthritis (OA) .

MMP13-IN-4	MMP	Metabolic Disease
MMP13-IN-4 (compound 13) is a potent and selective inhibitor of MMP-13 (IC₅₀=14.6 μM)，involved in osteoarthritis (OA) .

HY-146984

α-Amylase-IN-2	Glucosidase	Inflammation/Immunology
α-Glucosidase-IN-3 is an oleanolic acid (OA) oxime ester derivative against α-glucosidase (IC₅₀=1.28 µM) and α-amylase (IC₅₀=3.8 µM) .

HY-125415

PF-4693627	PGE synthase	Inflammation/Immunology
PF-4693627 is a potent, selective and orally bioavailable microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor (IC₅₀=3 nM) for the treatment of inflammation caused by osteoarthritis (OA) and rheumatoid arthritis (RA) .

HY-151524

Cathepsin K inhibitor 3	Cathepsin	Inflammation/Immunology
Cathepsin K inhibitor 3 (compound 23) is a highly selective cathepsin K inhibitor with an IC₅₀ value of 0.5 nM. Cathepsin K inhibitor 3 has a favorable pharmacokinetic profile and may be used in osteoarthritis (OA) disease studies .

HY-149378

MMP13-IN-5

MMP Metabolic Disease

MMP13-IN-5 (compound 13m) is a potent and selective inhibitor of MMP-2/MMP-13 (IC₅₀=3.6 μM/14.6 μM)，involved in osteoarthritis (OA) .

MMP13-IN-5	MMP	Metabolic Disease
MMP13-IN-5 (compound 13m) is a potent and selective inhibitor of MMP-2/MMP-13 (IC₅₀=3.6 μM/14.6 μM)，involved in osteoarthritis (OA) .

HY-W010320

Ethyl maltol 2-Ethyl-3-hydroxy-4H-pyran-4-one	Biochemical Assay Reagents	Others
Ethyl maltol (2-Ethyl-3-hydroxy-4H-pyran-4-one), an odor-active (OA) compound, is an important food additive and the main component of a type of incense added to food .

HY-W010320S

Ethyl maltol-d5 2-Ethyl-3-hydroxy-4H-pyran-4-one-d₅	Isotope-Labeled Compounds	Others
Ethyl maltol-d₅ is the deuterium labeled Ethyl maltol. Ethyl maltol (2-Ethyl-3-hydroxy-4H-pyran-4-one), an odor-active (OA) compound, is an important food additive and the main component of a type of incense added to food[1][2].

HY-100359

CL-82198 4 Publications Verification	MMP	Inflammation/Immunology Cancer
CL-82198 is a selective inhibitor of MMP-13. CL-82198 binds to the entire S1’ pocket of MMP-13, which is the basis for its selectivity towards MMP-13 and the lack of inhibitory activities against other MMPs . CL-82198 is a pharmacologic treatment for preventing osteoarthritis (OA) progression .

HY-N0801

Polygalacic acid	MMP Cholinesterase (ChE)	Neurological Disease Inflammation/Immunology
Polygalacic acid, is a triterpene, isolated from the root of Polygala tenuifolia Willd. Polygalacic acid inhibits MMP expression. Polygalacic acid may have a therapeutic effect in Osteoarthritis (OA) treatment . Polygalacic acid exerts a significant neuroprotective effect on cognitive impairment, PA improves cholinergic system reactivity by inhibiting acetylcholinesterase (AChE) activity, increasing choline acetyltransferase (ChAT) activity, and elevating levels of acetylcholine (Ach) in the hippocampus and frontal cortex .

HY-13507

Lumiracoxib COX-189	COX	Metabolic Disease Inflammation/Immunology Cancer
Lumiracoxib is a potent,selective and orally active COX-2 inhibitor with a K_i value of 0.06 μM . Lumiracoxib acts as a nonselective NSAID with anti-inflammatory, analgesic and antipyretic activities. Lumiracoxib can be used for osteoarthritis and bone cancer research .

HY-N8060A

Orotidine 5′-monophosphate trisodium Orotidine monophosphate trisodium; Orotidylic acid trisodium	Endogenous Metabolite DNA/RNA Synthesis	Metabolic Disease
Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide. Orotidine 5'-monophosphate trisodium is synthesized via the de novo synthesis pathway for DNA synthesis in a large number of microorganisms including M. tuberculosis, S. cerevisiae, S. typhimurium and P. falciparum to name a few. The synthesis of orotidine 5'-monophosphate trisodium uses phosphoribosyl pyrophosphate (PRPP) and orotic acid (OA) as the substrates catalyzed by orotate phosphoribosyltransferase (OPRT) .

HY-N1584

Halofuginone 5+ Cited Publications RU-19110	DNA/RNA Synthesis TGF-beta/Smad Parasite Sodium Channel Calcium Channel	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Halofuginone (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a K_i of 18.3 nM . Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity . Halofuginone is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca ²⁺ channels. Halofuginone has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects .

HY-N1584A

Halofuginone hydrobromide 5+ Cited Publications RU-19110 hydrobromide	DNA/RNA Synthesis TGF-beta/Smad Parasite Sodium Channel Calcium Channel	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Halofuginone (RU-19110) hydrobromid, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a K_i of 18.3 nM . Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity . Halofuginone hydrobromid is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca ²⁺ channels. Halofuginone hydrobromid has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects .

HY-108672

NF157	P2Y Receptor	Inflammation/Immunology
NF157 is a highly selective nanomolar P2Y11 antagonist with a pK_i of 7.35. The IC₅₀s are 463 nM, 1811 µM, 170 µM for P2Y11 (K_i=44.3 nM), P2Y1 (K_i=187 µM), P2Y2 (K_i=28.9 µM), respectively . NF157, significantly reduces expression of metalloproteinase (MMP)-3, MMP-13, can be used in the treatment of osteoarthritis (OA) .

HY-N1584B

Halofuginone hydrochloride RU-19110 hydrochloride	Calcium Channel DNA/RNA Synthesis Parasite Sodium Channel TGF-beta/Smad	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Halofuginone (RU-19110) hydrobromid, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a K_i of 18.3 nM. Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone hydrobromid is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca ²⁺ channels. Halofuginone hydrobromid has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects .

HY-122624

MMP13-IN-2	MMP	Inflammation/Immunology
MMP13-IN-2 is a potent, selective and orally active MMP-13 inhibitor. MMP13-IN-2 exhibits excellent potency for MMP-13 (IC₅₀=0.036 nM) and selectivities (greater than 1,500-fold) over MMP-1, 3, 7, 8, 9, 14, and TACE. MMP13-IN-2 has the ability to block the release of collagen from cartilage in vitro. MMP13-IN-2 has the potential for collagenase related disease research .

MMP-13 Substrate	MMP	Inflammation/Immunology
MMP-13 Substrate is a substrate of MMP-13. MMP-13 Substrate can be used for the research of osteoarthritis (OA) .

Fasinumab	Inhibitory Antibodies	Inflammation/Immunology
Fasinumab (Anti-Human NGF) is a human IgG4 monoclonal antibody to nerve growth factor (NGF). Fasinumab can be used in acute sciatica and knee osteoarthritis (OA) studies .

Frunevetmab NV-02	Inhibitory Antibodies	Inflammation/Immunology
Frunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a K_d of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-121936

Yohimbic acid	Cardiovascular Disease Alkaloids Structural Classification other families Classification of Application Fields Source classification Plants Isoquinoline Alkaloids Disease Research Fields Indole Alkaloids	Others
Yohimbic acid is an amphoteric demethylated derivative of Yohimbine. Yohimbic acid exhibits vasodilatory action. Yohimbic acid also can be used for the research of osteoarthritis (OA) .

HY-121936A

Yohimbic acid hydrate	Alkaloids Structural Classification other families Plants Isoquinoline Alkaloids Indole Alkaloids	Others
Yohimbic acid hydrate is an amphoteric demethylated derivative of Yohimbine (HY-12715). Yohimbic acid hydrate exhibits vasodilatory action. Yohimbic acid hydrate also can be used for the research of osteoarthritis (OA) .

HY-N0665

Specnuezhenide 1 Publications Verification (8E)-Nuezhenide	Monophenols Iridoids Classification of Application Fields Oleaceae Ligustrum lucidum Ait. Terpenoids Source classification Phenols Plants Inflammation/Immunology Disease Research Fields	NF-κB Wnt
Specnuezhenide ((8E)-Nuezhenide) is isolated from the fruits of Ligustrum lucidum. Specnuezhenide ((8E)-Nuezhenide) can inhibit IL-1β-induced inflammation in chondrocytes via inhibition of NF-κB and wnt/β-catenin signaling. Specnuezhenide ((8E)-Nuezhenide) exerts anti-inflammatory effects in a rat model of osteoarthritis (OA) .

HY-N0866

20-Deoxyingenol 1 Publications Verification	Classification of Application Fields Terpenoids Source classification Euphorbia kansui T. N. Liou ex S. B. Ho Diterpenoids Euphorbiaceae Plants Inflammation/Immunology Disease Research Fields	Autophagy
20-Deoxyingenol, a diterpene, is isolated from the roots of Euphorbia kansui. 20-Deoxyingenol can promote autophagy and lysosomal biogenesis by promoting the nuclear translocation of transcription factor EB (TFEB) in vitro. 20-Deoxyingenol can be used for the research of osteoarthritis (OA) .

HY-N0801

Polygalacic acid	Triterpenes Terpenoids Source classification Polygalaceae Plants Polygala tenuifolia Willd.	MMP Cholinesterase (ChE)
Polygalacic acid, is a triterpene, isolated from the root of Polygala tenuifolia Willd. Polygalacic acid inhibits MMP expression. Polygalacic acid may have a therapeutic effect in Osteoarthritis (OA) treatment . Polygalacic acid exerts a significant neuroprotective effect on cognitive impairment, PA improves cholinergic system reactivity by inhibiting acetylcholinesterase (AChE) activity, increasing choline acetyltransferase (ChAT) activity, and elevating levels of acetylcholine (Ach) in the hippocampus and frontal cortex .

HY-N8060A

Orotidine 5′-monophosphate trisodium Orotidine monophosphate trisodium; Orotidylic acid trisodium	Alkaloids Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite DNA/RNA Synthesis
Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide. Orotidine 5'-monophosphate trisodium is synthesized via the de novo synthesis pathway for DNA synthesis in a large number of microorganisms including M. tuberculosis, S. cerevisiae, S. typhimurium and P. falciparum to name a few. The synthesis of orotidine 5'-monophosphate trisodium uses phosphoribosyl pyrophosphate (PRPP) and orotic acid (OA) as the substrates catalyzed by orotate phosphoribosyltransferase (OPRT) .

HY-N1584

Halofuginone Maximum Cited Publications 9 Publications Verification RU-19110	Infection Cardiovascular Disease Alkaloids Piperidine Alkaloids Structural Classification Classification of Application Fields Dichroa febrifuga Lour Source classification Saxifragaceae Plants Inflammation/Immunology Disease Research Fields	DNA/RNA Synthesis TGF-beta/Smad Parasite Sodium Channel Calcium Channel
Halofuginone (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a K_i of 18.3 nM . Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity . Halofuginone is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca ²⁺ channels. Halofuginone has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects .

HY-N1584A

Halofuginone hydrobromide Maximum Cited Publications 9 Publications Verification RU-19110 hydrobromide	Infection Cardiovascular Disease Alkaloids Piperidine Alkaloids Structural Classification Classification of Application Fields Dichroa febrifuga Lour Source classification Saxifragaceae Plants Inflammation/Immunology Disease Research Fields	DNA/RNA Synthesis TGF-beta/Smad Parasite Sodium Channel Calcium Channel
Halofuginone (RU-19110) hydrobromid, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a K_i of 18.3 nM . Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity . Halofuginone hydrobromid is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca ²⁺ channels. Halofuginone hydrobromid has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects .

Species:	Human (8) Rhesus Macaque (2) Mouse (2) Cynomolgus (2)
Tag:	His (6) Avi (4) Fc (6)
Source:	HEK293 (12)

Cat. No.	Compare	Product Name	Species	Source

HY-P7335

	CD47 Protein, Human (HEK293, Fc) rHuCD47, Fc Chimera; MER6; IAP; OA3	Human	HEK293
	CD47 Protein, Human (HEK293, Fc) is a polypeptide chain with the C-terminal human IgG1 Fc fragment produced in HEK293 cells. CD47 is a prominent target in cancer immunotherapy.

HY-P78561

	CD47 Protein, Human (Biotinylated, HEK293, mFc-Avi) CD47; MER6; IAP; OA3	Human	HEK293
	FITC-Labeled CD47, an adhesive protein, modulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, impacting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal, and immunoregulation. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor agent in blood pressure regulation, and is crucial for memory formation. CD47's interactions with SIRPA, SIRPG, and FAS/CD95 influence dendritic cell maturation, T-cell activation, apoptosis, and angiogenesis. As a monomer, CD47 intricately participates in diverse cellular and molecular pathways, contributing to physiological and pathological processes. CD47 Protein, Human (Biotinylated, HEK293, mFc-Avi) is the recombinant human-derived CD47 protein, expressed by HEK293, with C-mFc, C-Avi labeled tag. The total length of CD47 Protein, Human (Biotinylated, HEK293, mFc-Avi) is 121 a.a., with molecular weight of 60-66 kDa.

HY-P78908

	CD47 Protein, Human (Biotinylated, HEK293, Fc-Avi) CD47; MER6; IAP; OA3	Human	HEK293
	FITC-Labeled CD47, an adhesive protein, modulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, impacting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal, and immunoregulation. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor agent in blood pressure regulation, and is crucial for memory formation. CD47's interactions with SIRPA, SIRPG, and FAS/CD95 influence dendritic cell maturation, T-cell activation, apoptosis, and angiogenesis. As a monomer, CD47 intricately participates in diverse cellular and molecular pathways, contributing to physiological and pathological processes. CD47 Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived CD47 protein, expressed by HEK293, with C-Avi, C-hFc labeled tag. The total length of CD47 Protein, Human (Biotinylated, HEK293, Fc-Avi) is 121 a.a., with molecular weight of 55-66 kDa.

HY-P78711

	CD47 Protein, Mouse (HEK293, Fc) CD47; MER6; IAP; OA3	Mouse	HEK293
	CD47 Protein, an adhesive multifunctional protein, orchestrates cell-to-cell interactions, serving as a receptor for THBS1 and modulating integrin signaling via heterotrimeric G proteins. It plays a pivotal role in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, immunoregulation, and memory formation. CD47, a receptor for SIRPA, influences dendritic cell maturation, inhibits cytokine production, and mediates cell-cell adhesion. Additionally, it modulates pulmonary EDN1 signaling, supports blood pressure in response to THBS1-induced NO signaling, and contributes to memory formation. CD47's role in wound healing, stem cell self-renewal inhibition, and its interactions with THBS1, SIRPA, FAS/CD95, SIRPG, UBQLN1, UBQLN2, and possibly fibrinogen underscore its diverse impact on cellular processes. Existing as a monomer, CD47 exhibits intricate involvement in various cellular pathways. CD47 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CD47 protein, expressed by HEK293, with C-hFc labeled tag. The total length of CD47 Protein, Mouse (HEK293, Fc) is 122 a.a., with molecular weight of 60-70 kDa.

HY-P701266

	FITC-Labeled CD47 Protein, Human (HEK293, His) CD47; MER6; IAP; OA3	Human	HEK293
	CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. FITC-Labeled CD47 Protein, Human (HEK293, His) is the recombinant human-derived FITC-Labeled CD47 protein, expressed by HEK293 , with His labeled tag. The total length of FITC-Labeled CD47 Protein, Human (HEK293, His) is 121 a.a., with molecular weight of 35-45 kDa.

HY-P7336

	CD47 Protein, Human (HEK293, His) rHuCD47, His; CD47; MER6; IAP; OA3	Human	HEK293
	CD47 Protein, Human (HEK293, His) is a polypeptide chain with His tag produced in HEK293 cells. CD47 is a prominent target in cancer immunotherapy.

HY-P78094

	CD47 Protein, Human (Biotinylated, HEK293, Fc) CD47 glycoprotein; CD47 molecule; CD47; IAP; OA3; MER6	Human	HEK293
	CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. CD47 Protein, Human (Biotinylated, HEK293, Fc) is the recombinant human-derived CD47 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD47 Protein, Human (Biotinylated, HEK293, Fc) is 121 a.a., with molecular weight of 55-65 kDa.

HY-P78095

	CD47 Protein, Human (Biotinylated, HEK293, His-Avi) CD47 glycoprotein; CD47 molecule; CD47; IAP; OA3; MER6	Human	HEK293
	CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. CD47 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD47 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of CD47 Protein, Human (Biotinylated, HEK293, His-Avi) is 121 a.a., with molecular weight of 45-55 kDa.

HY-P700682

	CD47 Protein, Cynomolgus/Rhesus Macaque (HEK293, C-His) CD47 glycoprotein; CD47 molecule; CD47; IAP; OA3; MER6	Rhesus Macaque;Cynomolgus	HEK293
	CD47 is a leukocyte surface antigen, and high expression of CD47 helps tumors escape. CD47 inhibition leads to the activation of CD103+ dendritic cells, which leads to the recruitment and activation of natural killer cells and inhibits cancer development. CD47 Protein, Cynomolgus/Rhesus Macaque (HEK293, C-His) is the recombinant Rhesus Macaque, cynomolgus-derived CD47 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD47 Protein, Cynomolgus/Rhesus Macaque (HEK293, C-His) is 123 a.a., with molecular weight of 30-43 kDa.

HY-P72359

	CD47 Protein, Human (Biotinylated, HEK293, Avi-His) Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; IAP; MER6	Human	HEK293
	CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. CD47 Protein, Human (Biotinylated, HEK293, Avi-His) is the recombinant human-derived CD47 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of CD47 Protein, Human (Biotinylated, HEK293, Avi-His) is 121 a.a., with molecular weight of 30-55 kDa.

HY-P70820

	CD47 Protein, Mouse (HEK293, His) Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6	Mouse	HEK293
	CD47 Protein, an adhesive multifunctional protein, orchestrates cell-to-cell interactions, serving as a receptor for THBS1 and modulating integrin signaling via heterotrimeric G proteins. It plays a pivotal role in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, immunoregulation, and memory formation. CD47, a receptor for SIRPA, influences dendritic cell maturation, inhibits cytokine production, and mediates cell-cell adhesion. Additionally, it modulates pulmonary EDN1 signaling, supports blood pressure in response to THBS1-induced NO signaling, and contributes to memory formation. CD47's role in wound healing, stem cell self-renewal inhibition, and its interactions with THBS1, SIRPA, FAS/CD95, SIRPG, UBQLN1, UBQLN2, and possibly fibrinogen underscore its diverse impact on cellular processes. Existing as a monomer, CD47 exhibits intricate involvement in various cellular pathways. CD47 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD47 protein, expressed by HEK293, with C-6*His labeled tag. The total length of CD47 Protein, Mouse (HEK293, His) is 140 a.a., with molecular weight of 30-60 kDa.

HY-P7831

	CD47 Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) rRhIntegrin-associated protein/CD47, Fc; Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6	Rhesus Macaque;Cynomolgus	HEK293
	CD47 is a leukocyte surface antigen, and high expression of CD47 helps tumors escape. CD47 inhibition leads to the activation of CD103+ dendritic cells, which leads to the recruitment and activation of natural killer cells and inhibits cancer development. CD47 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived CD47 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD47 Protein, Rhesus Macaque (HEK293, Fc) is 121 a.a., with molecular weight of 60-90 kDa.

Cat. No.	Product Name	Chemical Structure

HY-W010320S

Ethyl maltol-d5
Ethyl maltol-d₅ is the deuterium labeled Ethyl maltol. Ethyl maltol (2-Ethyl-3-hydroxy-4H-pyran-4-one), an odor-active (OA) compound, is an important food additive and the main component of a type of incense added to food[1][2].

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