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Results for "

PCPA

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1368
    Fenclonine
    10+ Cited Publications

    4-Chloro-DL-phenylalanine; PCPA; CP-10188

    		 Tryptophan Hydroxylase Neurological Disease Cancer
    Fenclonine is a selective and irreversible tryptophan hydroxylase inhibitor, which is a rate-limiting enzyme in the biosynthesis of serotonin. Fenclonine can be used in carcinoid syndrome research .
    Fenclonine
  • HY-101456
    PCPA methyl ester hydrochloride
    2 Publications Verification

    4-Chloro-DL-phenylalanine methyl ester hydrochloride
    PCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride), a reversible tryptophan hydroxylase inhibitor, is a serotonin (5-HT) synthesis inhibitor. PCPA methyl ester hydrochloride crosses the blood brain barrier and reduces 5-HT central availability .
    <em>PCPA</em> methyl ester hydrochloride
  • HY-W019599
    4-Chloro-L-phenylalanine

    L-PCPA

    		 5-HT Receptor Tryptophan Hydroxylase Neurological Disease
    4-Chloro-L-phenylalanine (L-PCPA) is a 5-HT biosynthesis inhibitor. 4-Chloro-L-phenylalanine is also a nonspecific antagonist of both isoforms of tryptophan hydroxylase (TPH1 and TPH2) .
    4-Chloro-L-phenylalanine
  • HY-151190
    cis-4-Br-2,5-F2-PCPA

    S1024

    		 Histone Demethylase Cancer
    cis-4-Br-2,5-F2-PCPA (S1024) is a selective inhibitor of lysine-specific demethylase 1 (LSD1), with a Ki value of 94 nM instead of 8.4 μM for LSD2. There is aberrant expression of LSD1 in cancer stem cells, cis-4-Br-2,5-F2-PCPA inhibits LSD1 cell proliferation and by increasing the level of dimethylated histone H3 at K4 (H3K4) in CCRF-CEM cells .
    cis-4-Br-2,5-F2-<em>PCPA</em>
  • HY-151194
    LSD1/2-IN-4

    		Histone Demethylase Cancer
    LSD1/2-IN-4, a PCPA derivative, is an inhibitor of lysine-specific demethylase 1 (LSD1) and lysine-specific demethylase 2 (LSD2). LSD1/2-IN-4 inhibits LSD1 and LSD2 with Ki values of 0.11 μM and 130 μM, respectively. LSD1/2-IN-4 can be used for the research of several cancers including T-cell acute lymphoblastic leukemia (TALL) .
    LSD1/2-IN-4
  • HY-17555
    Meclofenoxate hydrochloride

    Centrophenoxine hydrochloride

    		 nAChR iGluR Neurological Disease
    Meclofenoxate hydrochloride is an ester synthesized from DMAE and pCPA, which has the activity of stimulating memory and improving cognition.
    Meclofenoxate hydrochloride
  • HY-17555A
    Meclofenoxate

    Centrophenoxine
    Meclofenoxate (Centrophenoxine) is an ester synthesized from DMAE and pCPA, which has the activity of stimulating memory and improving cognition .
    Meclofenoxate
  • HY-12645
    NCL1

    		Histone Demethylase Cancer
    NCL1 is a phenylcyclopropylamine (PCPA)-based Lysine-specific demethylase 1 (LSD1) inhibitor. NCL1 selectively inhibits LSD1 in preference to LSD2, with IC50 values of 2.5 and 26 μM for LSD1 and LSD2, respectively .
    NCL1
  • HY-151192
    LSD1/2-IN-3

    		Histone Demethylase Cancer
    LSD1/2-IN-3 is a selective inhibitor of lysine-specific demethylase 1 (LSD1), with a Ki value of 11 nM instead of 7 μM for LSD2. There is aberrant expression of LSD1 in cancer stem cells, LSD1/2-IN-1 inhibits LSD1 cell proliferation .
    LSD1/2-IN-3

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