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Results for "

PEG-3

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (119) ADC Payload (1) Amyloid-β (1) Anaplastic lymphoma kinase (ALK) (2) Androgen Receptor (1) Apoptosis (24) Aurora Kinase (1) AUTACs (4) Autophagy (26) AUTOTACs (2) Biochemical Assay Reagents (43) Btk (1) DNA/RNA Synthesis (3) Drug Derivative (6) Drug Intermediate (2) Drug-Linker Conjugates for ADC (15) E3 Ligase Ligand-Linker Conjugates (77) EGFR (4) Environmental Pollutants (1) Epigenetic Reader Domain (1) Estrogen Receptor/ERR (1) Ferroptosis (1) FKBP (1) Fluorescent Dye (29) Formyl Peptide Receptor (FPR) (1) Ligands for E3 Ligase (2) Ligands for Target Protein for PROTAC (1) MDM-2/p53 (1) Microtubule/Tubulin (2) Mixed Lineage Kinase (1) PD-1/PD-L1 (1) Phosphoramidites (2) PKA (1) PROTAC Linkers (432) PROTAC-Linker Conjugates for PAC (1) PROTACs (9) PSMA (2) Radionuclide-Drug Conjugates (RDCs) (5) Ras (1) Reactive Oxygen Species (ROS) (1) Reference Standards (4) SGK (2) Small Interfering RNA (siRNA) (4) Somatostatin Receptor (2) Target Protein Ligand-Linker Conjugates (3) Tau Protein (1) Topoisomerase (2)
By Research Areas:	Cancer (636) Cardiovascular Disease (1) Infection (2) Inflammation/Immunology (7) Metabolic Disease (1) Neurological Disease (4)
Click Chemistry:	ADC Synthesis (62) Labeling and Fluorescence Imaging (15) TCO (27) DBCO (30) PROTAC Synthesis (149) BCN (19) Azide (142) Tetrazine (10) Alkynes (42)
Oligonucleotides:	Rat Pre-designed siRNA Sets (2) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) Other Phosphoramidite (2) Phosphoramidites (2) siRNAs (4)

745

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Antibodies

267

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-164239

*NH2-PEG3-VC-PAB-MMAE*	Drug-Linker Conjugates for ADC Microtubule/Tubulin	Cancer
NH2-PEG3-VC-PAB-MMAE is a drug-linker conjugate for ADC, consisting of a cleavable ADC linker (NH2-PEG3-VC-PAB) and a potent tubulin inhibitor Monomethyl auristatin E (MMAE) (HY-15162). NH2-PEG3-VC-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-129526

*Mal-PEG3-NHS ester* 1 Publications Verification	ADC Linker	Cancer
Mal-PEG3-NHS ester is a noncleavable ADC linker containing a Maleimide group. Mal-PEG3-NHS ester is used for making antibody-drug conjugate .

HY-164792

*DBCO-PEG3-VC-Exatecan*	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
DBCO-PEG3-VC-Exatecan (compound 25) is a Drug-Linker Conjugate for ADC. DBCO-PEG3-VC-Exatecan contains the ADC linker (DBCO-PEG3-VC) and a DNA topoisomerase I inhibitor Exatecan (HY-13631) .

HY-W096121

*PEG3*	PROTAC Linkers	Cancer
PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-151696

*TCO-PEG3-maleimide*	ADC Linker	Others
TCO-PEG3-maleimide (TCO-PEG3-NEM) is a click chemistry reagent. TCO-PEG3-maleimide efficiently binds TCO (trans-cyclooctene) moiety to thiol-containing molecules (such as antibodies, cysteine-containing peptides) .

HY-154801

*Biotin-PEG3-CONH-Ph-CF3-diazirine* 1 Publications Verification	Biochemical Assay Reagents	Others
Biotin-PEG3-CONH-Ph-CF3-diazirine is a biotin labeled PEG3 derivative. Biotin-PEG3-CONH-Ph-CF3-diazirine can be used for protein labeling .

HY-126974

*Propargyl-PEG3-NHS ester*	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG3-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG3-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-126975

*Propargyl-PEG3-acid*	ADC Linker PROTAC Linkers	Inflammation/Immunology Cancer
Propargyl-PEG3-acid is a non-cleavable (3 unit PEG) ADC linker and also a PEG-based PROTAC linker that can be used to synthesis 6-OHDA-PEG3-yne. 6-OHDA-PEG3-yne contains 6-OHDA (HY-B1081, HY-B1081A) and Propargyl-PEG3-acid . Propargyl-PEG3-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-177546

*DBCO-PEG3-GGFG-Exatecan*	Drug-Linker Conjugates for ADC Drug Derivative Topoisomerase	Cancer
DBCO-PEG3-GGFG-Exatecan is a Drug-linker conjugate for ADC. DBCO-PEG3-GGFG-Exatecan contains the ADC linker (DBCO-PEG3-GGFG) and a DNA topoisomerase I inhibitor Exatecan (HY-13631) .

HY-156383

*SCO-PEG3-NHS*	PROTAC Linkers	Cancer
SCO-PEG3-NHS is a PEG linker with a terminal imine(NH) group. SCO-PEG3-NHS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-W018174

*m-PEG3-Amine* 1 Publications Verification	ADC Linker PROTAC Linkers	Cancer
m-PEG3-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-P5112A

*Azido-PEG3-DYKDDDDK TFA* Azido-PEG3-FLAG TFA	Biochemical Assay Reagents	Others
Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) TFA is a multifunctional fusion tag for the purification of recombinant proteins. Azido-PEG3-DYKDDDDK TFA is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .

HY-140106

*Azido-PEG3-SS-PEG3-azide*	PROTAC Linkers	Cancer
Azido-PEG3-SS-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-SS-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-134977

*Atrovastatin-PEG3-FITC*	Ras	Cancer
Atrovastatin-PEG3-FITC (compound S31) is a KRAS-PDEδ interaction inhibitor. Atrovastatin-PEG3-FITC acts as a ligand in fluorescence anisotropy assay .

HY-141287

*N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid*	PROTAC Linkers	Cancer
N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W190796

*Mal-PEG3-NH2*	PROTAC Linkers	Others
Mal-PEG3-NH2 is a linear heterobifunctional PEG reagent with a maleimide and an amine. Mal-PEG3-NH2 is a crosslinking reagent with a PEG spacer .

HY-23408

Tos-PEG3	PROTAC Linkers	Cancer
Tos-PEG3 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports .

HY-W872575

*TCO4-PEG3-Maleimide*	PROTAC Linkers	Cancer
TCO4-PEG3-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG3-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.

HY-P5112

*Azido-PEG3-DYKDDDDK* Azido-PEG3-FLAG	Biochemical Assay Reagents	Others
Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) is a multifunctional fusion tag for the purification of recombinant proteins. Azido-PEG3-DYKDDDDK is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .

HY-169089

*RP-182-PEG3-K(palmitic acid)-NH2*	Drug Derivative	Cancer
RP-182-PEG3-K palmitic acid-NH2 (Compound 1a) is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K palmitic acid-NH2 inhibits CD206 ^high M2-like macrophage (IC₅₀ of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K palmitic acid-NH2 exhibits antitumor efficacy in mouse B16 melanoma allografts .

HY-153672

*Amine-PEG3-Lys(PEG3-N3)-PEG3-N3*	ADC Linker	Cancer
Amine-PEG3-Lys(PEG3-N3)-PEG3-N3 (compound 5) is a branched linker that can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W674534

*Boc-PEG3-mesylate*	PROTAC Linkers	Cancer
Boc-PEG3-mesylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-130871A

*HS-PEG3-CH2CH2NH2 hydrochloride* Thiol-PEG3-amine hydrochloride	PROTAC Linkers	Cancer
HS-PEG3-CH2CH2NH2 hydrochloride (Thiol-PEG3-amine hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-D2143

*Cy5-PEG3-TCO*	Fluorescent Dye	Others
Cy5-PEG3-TCO is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-TCO utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.

HY-140246

*N-(PEG3-acid)-N-bis(PEG3-amine)*	PROTAC Linkers	Cancer
N-(PEG3-acid)-N-bis(PEG3-amine) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-161130

*Lenalidomide 4'-PEG3-amine dihydrochloride*	E3 Ligase Ligand-Linker Conjugates	Cancer
Lenalidomide 4'-PEG3-amine dihydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide 4'-PEG3-amine dihydrochloride can be connected to the ligand for protein by a linker to form PROTAC .

HY-128804

PEG3-O-CH2COOH PROTAC Linker 8	PROTAC Linkers	Cancer
PEG3-O-CH2COOH (PROTAC Linker 8) is a PEG-based PROTAC linker can be used in the synthesis of SNIPERs .

HY-169089A

*RP-182-PEG3-K(palmitic acid)-NH2 TFA*	Drug Derivative	Cancer
RP-182-PEG3-K(palmitic acid)-NH2 (Compound 1a) TFA is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K(palmitic acid)-NH2 TFA inhibits CD206 ^high M2-like macrophage (IC₅₀ of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K(palmitic acid)-NH2 TFA exhibits antitumor efficacy in mouse B16 melanoma allografts .

HY-136084

*Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO)*	ADC Linker	Cancer
Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO) is a cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO) is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

HY-140552

*N-(Azido-PEG3)-NH-PEG3-acid*	PROTAC Linkers	Cancer
N-(Azido-PEG3)-NH-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-NH-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140526

*N-(Azido-PEG3)-N-Boc-PEG3-acid*	PROTAC Linkers	Cancer
N-(Azido-PEG3)-N-Boc-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-143849

*N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) hydrochloride*	PROTAC Linkers	Cancer
N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-140247

*N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid*	PROTAC Linkers	Cancer
N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-44063

*Thalidomide-NH-PEG3-NH-Boc*	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-NH-PEG3-NH-Boc is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-NH-PEG3-NH-Boc acts as a ligand for Cereblon to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-NH-PEG3-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-NH-PEG3-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules.

HY-174945

*DSPE-PEG3-azide* DSPE-PEG3-N3	Biochemical Assay Reagents	Others
DSPE-PEG3-azide (DSPE-PEG3-N3) is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery. DSPE-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .

HY-47373

*Folate-PEG3-C2-acid*	PROTAC Linkers	Cancer
Folate-PEG3-C2-acid is the acid fragment of Folate-PEG3-NHS ester (HY-133493), which belongs to the PEG-type PROTAC linker and is used to synthesize PROTAC molecules.

HY-130620

PEG3-C4-OBn	PROTAC Linkers	Cancer
PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. PEG3-C4-OBn can be used in the synthesis of the PROTAC SGK3 degrader-1 (HY-125878). PROTAC SGK3 degrader-1 is a potent SKG3 degrader based on PROTAC .

HY-RS10319

PEG3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PEG3 Human Pre-designed siRNA Set A contains three designed siRNAs for PEG3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PEG3 Human Pre-designed siRNA Set A PEG3 Human Pre-designed siRNA Set A

HY-140607

m-PEG3-Sulfone-PEG3	PROTAC Linkers	Cancer
m-PEG3-Sulfone-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-140605

*m-PEG3-Sulfone-PEG3-acid*	PROTAC Linkers	Cancer
m-PEG3-Sulfone-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-140611

*Propargyl-peg3-sulfone-peg3-propargyl*	PROTAC Linkers	Cancer
Propargyl-peg3-sulfone-peg3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-peg3-sulfone-peg3-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140113

*Acid-PEG3-SS-PEG3-acid*	ADC Linker	Cancer
Acid-PEG3-SS-PEG3-acid is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-140609

*m-PEG3-Sulfone-PEG3-Boc*	PROTAC Linkers	Cancer
m-PEG3-Sulfone-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-135963

*Thiol-PEG3-thiol* Bis-PEG3-thiol	Biochemical Assay Reagents	Others
Thiol-PEG3-thiol (Bis-PEG3-thiol) is a thiol crosslinker used in the synthesis of PEG hydrogels.

HY-140596

*m-PEG3-S-PEG3-Boc*	PROTAC Linkers	Cancer
m-PEG3-S-PEG3-Boc is a PEG- and Alkyl/ether -based PROTAC linker can be used in the synthesis of PROTACs .

HY-140245

*N-(Amino-PEG3)-N-bis(PEG3-acid)*	PROTAC Linkers	Cancer
N-(Amino-PEG3)-N-bis(PEG3-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-140536

*N-(Boc-PEG3)-N-bis(PEG3-acid)*	PROTAC Linkers	Cancer
N-(Boc-PEG3)-N-bis(PEG3-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-140603

*Azide-PEG3-Sulfone-PEG3-azide*	PROTAC Linkers	Cancer
Azide-PEG3-Sulfone-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG3-Sulfone-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140590

*Azido-PEG3-S-PEG3-azide*	PROTAC Linkers	Cancer
Azido-PEG3-S-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-S-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140606

*m-PEG3-Sulfone-PEG3-azide*	PROTAC Linkers	Cancer
m-PEG3-Sulfone-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . m-PEG3-Sulfone-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No.	Product Name	Type

HY-111377

*Amine-PEG3-Biotin* 3 Publications Verification	Fluorescent Dye
Amine-PEG3-Biotin is a signal amplification label containing a biotin group and a terminal primary amine group .

HY-149618

*Cy5-PEG3-endo-BCN*	Fluorescent Dye
Cy5-PEG3-endo-BCN is a derivative of the Cyanine 5 (Cy5) (HY-D0821) dye bearing 3 PEG units. Cy5-PEG3-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, endo-BCN forms stable triazoles with azide-containing molecules under catalyst-free conditions .

HY-135835

6-FAM-PEG3-Azide

Fluorescent Dye

6-FAM-PEG3-Azide is a fluorescent dye that can be used to label oligonucleotide . 6-FAM-PEG3-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-D2353

Biotin-PEG3-benzophenone

Fluorescent Dye

Biotin-PEG3-benzophenone is biotin-labeled Benzophenone (HY-Y0546). Benzophenone is an endogenous metabolite and a photosensitizer that has been implicated in photosensitive damage to DNA. Benzophenone causes nucleobase oxidation, formation of cyclobutane-pyrimidine dimers, single-strand breaks, DNA-protein cross-links or abasic sites, different pathologies that may occur in nucleosides, oligonucleotides or DNA .

HY-D2143

*Cy5-PEG3-TCO*	Fluorescent Dye
Cy5-PEG3-TCO is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-TCO utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.

HY-D2113

*TAMRA-PEG3-Alkyne*	Fluorescent Dye
TAMRA-PEG3-Alkyne is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-101974

Biotin-PEG3-Bromide

Fluorescent Dye

Biotin-PEG3-Bromide is a short PEG linker featuring a biotin group and a bromide. The bromide is a halogen which is easily displaced by nucleophiles such as alcohols or amines. Alternatively, bromide can be applied in a number of cross-coupling reactions such as in a Suzuki reaction. Biotin is useful for affinity-based applications such as pull-down assays or for ligating with streptavidin proteins.

HY-D2101

*TAMRA-PEG3-NH2*	Fluorescent Dye
TAMRA-PEG3-NH2 is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-NH2 contains NH2 groups, which can undergo condensation reactions with carboxyl groups to form covalent bonds.

HY-130768

N-(Azido-PEG3)-N-Fluorescein-PEG3-acid

Fluorescent Dye

N-(Azido-PEG3)-N-Fluorescein-PEG3-acid is a PEG-based PROTAC linker which contains azide, fluorescein and carboxylic acid moieties. N-(Azido-PEG3)-N-Fluorescein-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-D2105

*TAMRA-PEG3-NHS*	Fluorescent Dye
TAMRA-PEG3-NHS is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-NHS contains NHS groups that react with ammonia to form ester bonds.

HY-D2123

*Cy3-PEG3-SCO*	Fluorescent Dye
Cy5-PEG3-SCO is a fluorescent dye that reacts with tetrazines and azides.

HY-D2226

*Sulfo-Cy5-PEG3-Biotin*	Fluorescent Dye
Sulfo-Cy5-PEG3-Biotin is a fluorescent dye.

HY-D2103

*TAMRA-PEG3-Maleimide*	Fluorescent Dye
TAMRA-PEG3-Maleimide is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Maleimide contains maleimide groups that react with thiol groups to form covalent bonds.

HY-D2108

*TAMRA-PEG3-COOH*	Fluorescent Dye
TAMRA-PEG3-COOH is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.

HY-D2139

*Cy3-PEG3-Alkyne*	Fluorescent Dye
Cy3-PEG3-Alkyne is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D2134

*Cy5-PEG3-Tetrazin*	Fluorescent Dye
Cy5-PEG3-Tetrazin is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-Tetrazin contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-155323

*Cy3-PEG3-TCO*	Fluorescent Dye
Cy3-PEG3-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.

HY-D2152

*Cy5-PEG3-SCO*	Fluorescent Dye
Cy5-PEG3-SCO is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-SCO has a SCO group that can be covalently bonded to the amino group. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.

HY-D1870

Sulfo-Cy3-PEG3-biotin potassium

Fluorescent Dye

Sulfo-Cy3-PEG3-biotin potassium is a biotin-modified derivative of Cy3 (Cyanine3) (HY-D0822) dye containing a TCO group. The TCO group of Sulfo-Cy3-PEG3-biotin potassium reacts with the tetrazine functional group in highly specific click chemistry to form a covalent bond. Thus, Sulfo-Cy3-PEG3-biotin potassium can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples. And because it is labeled with biotin, it is often used in affinity chromatography experiments, such as immunoprecipitation.

HY-156306

*Coumarin-PEG3-TCO*	Fluorescent Dye
Coumarin-PEG3-TCO is a dye derivative of Coumarin (HY-N0709) containing 3 PEG units. Coumarin-PEG3-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.

HY-D2146

*Cy5-PEG3-TCO4*	Fluorescent Dye
Cy5-PEG3-TCO4 is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-TCO4 utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.

HY-155326

*Cy3-PEG3-TCO4*	Fluorescent Dye
Cy3-PEG3-TCO4 is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-TCO4 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.

HY-D2137

*Cy3-PEG3-Azide*	Fluorescent Dye
Cy3-PEG3-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 3 PEG units. Cy3-PEG3-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-D2118

*TAMRA-PEG3-Me-Tet*	Fluorescent Dye
TAMRA-PEG3-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-D2120A

*Cy3-PEG3-exo-BCN*	Fluorescent Dye
Cy3-PEG3-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-D2120

*Cy3-PEG3-endo-BCN*	Fluorescent Dye
Cy3-PEG3-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-endo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-140938A

*(Rac)-Biotin-PEG3-oxyamine hydrochloride*	Fluorescent Dye
(Rac)-Biotin-PEG3-oxyamine hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-135635

*ABL-001-Amide-PEG3-acid*	Fluorescent Dye
ABL-001-Amide-PEG3-acid, an analogue of ABL-001, is usually used as a labeled chemical or fluorescent probe.

Cat. No.	Product Name	Type

HY-W879049

*DBCO-PEG3-Maleimide* DBCO-NHCO-PEG3-maleimide	Biochemical Assay Reagents
DBCO-PEG3-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG3-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .

HY-W042449

*TBDMS-PEG3-OH*	Biochemical Assay Reagents
TBDMS-PEG3-OH is a PEG derivative that can be used for drug delivery and other research .

HY-174938

*Biotin-PEG3-Iodoacetamide*	Biochemical Assay Reagents
Biotin-PEG3-Iodoacetamide is a PEG derivative composed of Biotin, 3 PEG units, and Iodoacetamide. Biotin can form a stable non-covalent bond with streptavidin.

HY-174924

*Cholesterol-PEG3-azide*	Biochemical Assay Reagents
Cholesterol-PEG3-azide is a PEG derivative composed of Cholesterol, 3 PEG units and an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition reaction (SPAAC) with molecules containing DBCO or BCN groups.

HY-174945

DSPE-PEG3-azide

DSPE-PEG3-N3

Biochemical Assay Reagents

DSPE-PEG3-azide (DSPE-PEG3-N3) is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery. DSPE-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .

HY-163790

*Desthiobiotin-PEG3-sulfo-Maleimide*	Biochemical Assay Reagents
Desthiobiotin-PEG3-sulfo-Maleimide is a PEG linker can be used in the synthesis of PROTACs .

HY-135963

*Thiol-PEG3-thiol* Bis-PEG3-thiol	Biochemical Assay Reagents
Thiol-PEG3-thiol (Bis-PEG3-thiol) is a thiol crosslinker used in the synthesis of PEG hydrogels.

HY-163789

*Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide*	Biochemical Assay Reagents
Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-174925

*Thalidomide-O-PEG3-COOH*	Biochemical Assay Reagents
Thalidomide-O-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology .

HY-131455A

Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 TFA

Biochemical Assay Reagents

Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 TFA is used for detection of modification site for N-myristoylated and GPI-anchored proteins in blood-stage P. falciparum . Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 (TFA) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W796380

*Allyl-PEG3-OH* Acryloyl-PEG3-OH	Biochemical Assay Reagents
Allyl-PEG3-OH (Acryloyl-PEG3-OH) is a PEG derivative with a hydroxyl (OH) functional group that can be used for drug delivery.

HY-174937

*DNP-PEG3-acid* DNP-PEG3-COOH	Biochemical Assay Reagents
DNP-PEG3-acid (DNP-PEG3-COOH) is a compound composed of 2,4-dinitroaniline (DNP), three PEG units, and propionic acid, which can be used for drug delivery.

HY-W190745B

*DNP-PEG3-NHS ester*	Biochemical Assay Reagents
DNP-PEG3-NHS ester is a PEG derivative that contains DNP (2,4-dinitroaniline), three PEG units, and NHS ester. NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). DNP-PEG3-NHS ester can be used for drug delivery.

HY-W190756

*DNP-PEG3-NH2*	Biochemical Assay Reagents
DNP-PEG3-NH2 is a PEG derivative that can be used for drug delivery research.

Cat. No.	Product Name	Target	Research Area

HY-P5112A

*Azido-PEG3-DYKDDDDK TFA* Azido-PEG3-FLAG TFA	Biochemical Assay Reagents	Others
Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) TFA is a multifunctional fusion tag for the purification of recombinant proteins. Azido-PEG3-DYKDDDDK TFA is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .

HY-P5112

*Azido-PEG3-DYKDDDDK* Azido-PEG3-FLAG	Biochemical Assay Reagents	Others
Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) is a multifunctional fusion tag for the purification of recombinant proteins. Azido-PEG3-DYKDDDDK is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .

HY-169089

*RP-182-PEG3-K(palmitic acid)-NH2*	Drug Derivative	Cancer
RP-182-PEG3-K palmitic acid-NH2 (Compound 1a) is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K palmitic acid-NH2 inhibits CD206 ^high M2-like macrophage (IC₅₀ of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K palmitic acid-NH2 exhibits antitumor efficacy in mouse B16 melanoma allografts .

HY-169089A

*RP-182-PEG3-K(palmitic acid)-NH2 TFA*	Drug Derivative	Cancer
RP-182-PEG3-K(palmitic acid)-NH2 (Compound 1a) TFA is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K(palmitic acid)-NH2 TFA inhibits CD206 ^high M2-like macrophage (IC₅₀ of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K(palmitic acid)-NH2 TFA exhibits antitumor efficacy in mouse B16 melanoma allografts .

HY-P10319

RI-STAD-2	PKA	Cardiovascular Disease Cancer
RI-STAD-2 is a high-affinity interfering peptide that regulates the subunit RI of protein kinase A (PKA). RI-STAD-2 interferes with the binding of AKAPs and PKA-RI by simulating the interaction between AKAPs' α-helix domain and PKA-RI's dimerization/anchoration (D/D) domain, thereby affecting PKA activity and intracellular localization. RI-STAD-2 can be used to study the role of AKAPs interaction with PKA-RI in pathological processes such as cardiovascular disease and cancer .

HY-P11488

*JR11-PEG3-DOTA-PSMA-03*	Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor PSMA	Cancer
JR11-PEG3-DOTA-PSMA-03 (Compound 2) is an RDC-related compound containing the chelating agent DOTA (HY-W053583), the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-DOTA-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC₅₀ s of 94.0 nM, 81.8 nM, respectively. JR11-PEG3-DOTA-PSMA-03 can be radiolabeled with [ ⁶⁸Ga]. [ ⁶⁸Ga] radiolabeled JR11-PEG3-DOTA-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .

HY-P11485

*JR11-PEG3-HBED-CC-PSMA-03*	Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor PSMA	Cancer
JR11-PEG3-HBED-CC-PSMA-03 (Compound 1) is an RDC-related compound containing the chelating agent HBED-CC, the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-HBED-CC-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC₅₀ s of 59.2 nM, 57.0 nM, respectively. JR11-PEG3-HBED-CC-PSMA-03 can be radiolabeled with [ ⁶⁸Ga]. [ ⁶⁸Ga] radiolabeled JR11-PEG3-HBED-CC-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .

HY-P11718

cFLFLF	Formyl Peptide Receptor (FPR) Radionuclide-Drug Conjugates (RDCs)	Inflammation/Immunology
cFLFLF is a FPR-specific peptide. cFLFLF is sequentially conjugated with a bifunctional polyethylene glycol moiety (PEG, 3.4 kD) and a DOTA through a lysine (K) spacer and finally labeled with ⁶⁴Cu-CuCl₂ to form cFLFLFKPEG- ⁶⁴Cu. cFLFLFKPEG- ⁶⁴Cu is a neutrophil-specific PET imaging agent .

Species:	Human (3)
Tag:	His (2) Tag Free (1) Myc (1)
Source:	E. coli (3)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P701811

	MELK Protein, Human (His) MELK; Maternal embryonic leucine zipper kinase; hMELK; Protein kinase Eg3; PEG3 kinase; Protein kinase PK38; hPK38; Tyrosine-protein kinase MELK	Human	E. coli
	MELK is a multifunctional serine/threonine protein kinase that regulates the cell cycle, stem cell self-renewal, apoptosis, and splicing. MELK phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622, activates apoptosis through MAP3K5/ASK1, helps CDC25B localize during mitosis, and inhibits BCL2L14, which may affect breast cancer occurrence. MELK Protein, Human (His) is the recombinant human-derived MELK protein, expressed by E. coli , with N-6*His labeled tag.

HY-P701810

	MELK Protein, Human (Active) MELK; Maternal embryonic leucine zipper kinase; hMELK; Protein kinase Eg3; PEG3 kinase; Protein kinase PK38; hPK38; Tyrosine-protein kinase MELK	Human	E. coli
	MELK is a multifunctional serine/threonine protein kinase that regulates the cell cycle, stem cell self-renewal, apoptosis, and splicing. MELK phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622, activates apoptosis through MAP3K5/ASK1, helps CDC25B localize during mitosis, and inhibits BCL2L14, which may affect breast cancer occurrence. MELK Protein, Human is the recombinant human-derived MELK protein, expressed by E. coli , with tag free.

HY-P705043

	MELK Protein, Human (340a.a, His, Myc) MELK; Maternal embryonic leucine zipper kinase; hMELK; Protein kinase Eg3; PEG3 kinase; Protein kinase PK38; hPK38; Tyrosine-protein kinase MELK	Human	E. coli

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Host:	Mouse (2) Rabbit (1)
Reactivity:	Human (3)
Application:	IHC-P (2) WB (1)
Isotype:	IgG (1) IgG1 (2)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

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HY-P89004

	PEG3 Antibody (YA8688) PW1; ZKSCAN22; ZNF904; ZSCAN24	IHC-P	Human
	PEG3 Antibody (YA8688) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PEG3.

HY-P89004A

	PEG3 Antibody (YA8688)(PBS only) PW1; ZKSCAN22; ZNF904; ZSCAN24	IHC-P	Human
	PEG3 Antibody (YA8688) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PEG3.

HY-P81678

	MELK Antibody (YA1423) MELK; KIAA0175; Maternal embryonic leucine zipper kinase; hMELK; Protein kinase Eg3; PEG3 kinase; Protein kinase PK38; hPK38; Tyrosine-protein kinase MELK	WB	Human
	MELK Antibody (YA1423) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MELK.

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PEG-3

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Fluorescent Dye

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