PGI

By Targets:	Endogenous Metabolite (4) Isotope-Labeled Compounds (3) Microtubule/Tubulin (1) Prostaglandin Receptor (9)
By Research Areas:	Cancer (2) Cardiovascular Disease (8) Endocrinology (7) Inflammation/Immunology (3) Metabolic Disease (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W011184

6-Phosphogluconic acid trisodium	Endogenous Metabolite	Metabolic Disease
6-Phosphogluconic acid trisodium is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with K_is of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite .

HY-112322

Carbacyclin Carbaprostacyclin; Carba-PGI2	Prostaglandin Receptor	Cardiovascular Disease Endocrinology
Carbacyclin is a PGI2 analogue, acts as a *prostacyclin (PGI2) receptor* agonist and vasodilator, and potently inhibits platelet aggregation.

HY-130594

6α-Prostaglandin I1

6α-PGI1
Others Others

6α-Prostaglandin I1 (6α-PGI1) is an analogue of prostacycline I2 (PGI2) and is resistant to hydrolysis in aqueous solution .

6α-Prostaglandin I1 6α-PGI1	Others	Others
6α-Prostaglandin I1 (6α-PGI1) is an analogue of prostacycline I2 (PGI2) and is resistant to hydrolysis in aqueous solution .

HY-130522

6β-Prostaglandin I1 6β-PGI1	Others	Others
6β-Prostaglandin I1 (6β-PGI1) is an analog of prostaglandin I2 (PGI2) that is resistant to hydrolysis in aqueous solutions. 6β-Prostaglandin I1 can reduce gastric acid secretion with an ID₅₀ (dose causing 50% inhibition) of approximately 3.0 μg/kg/min (intravenous injection) .

HY-113514

6-Phosphogluconic acid	Endogenous Metabolite	Metabolic Disease
6-Phosphogluconic acid is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with K_is of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid is an endogenous metabolite .

HY-A0096S

Iloprost-d4	Isotope-Labeled Compounds Prostaglandin Receptor	Endocrinology
Iloprost-d₄ (Ciloprost-d4) is the deuterium labeled Iloprost. Iloprost (ZK 36374) is a synthetic analogue of prostacyclin PGI2[1][2].

HY-120123

FR181157

Prostaglandin Receptor Inflammation/Immunology

FR181157, an orally active PGI₂ agonist activity with especially good pharmacokinetic properties .

FR181157	Prostaglandin Receptor	Inflammation/Immunology
FR181157, an orally active *PGI₂* agonist activity with especially good pharmacokinetic properties .

HY-14870

Selexipag 2 Publications Verification NS-304; ACT-293987	Prostaglandin Receptor	Cardiovascular Disease Endocrinology
Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin (PGI₂) receptor (IP receptor).

HY-107348

Etofylline clofibrate	Others	Cardiovascular Disease
Etofylline clofibrate has ypolipidemic and antithrombotic effect. Etofylline clofibrate has an agonistic interaction with intimal PGI2 .

HY-124363

5-cis Carbaprostacyclin	Others	Cardiovascular Disease
5-cis Carbaprostacyclin is a stable analog of PGI2. 5-cis Carbaprostacyclin induces relaxant effect in pulmonary vascular tone .

HY-14870S3

Selexipag-d6 NS-304-d₆; ACT-293987-d₆	Isotope-Labeled Compounds Prostaglandin Receptor	Cardiovascular Disease Endocrinology
Selexipag-d₆ is deuterium labeled Selexipag. Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin (PGI2) receptor (IP receptor).

HY-14870S1

Selexipag-d7	Isotope-Labeled Compounds Prostaglandin Receptor	Cardiovascular Disease Endocrinology
Selexipag-d₇ is the deuterium labeled Selexipag. Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin (PGI2) receptor (IP receptor)[1][2].

HY-100283

CGS 15435	Others	Inflammation/Immunology Endocrinology
CGS 15435, a potent thromboxane (TxA₂) synthetase inhibitor with an IC₅₀ of 1 nM, has a selectivity for Tx synthetase 100000-fold greater than that for cyclooxygenase, PGI₂ synthetase and lipoxygenase enzymes.

HY-A0096

Iloprost 3 Publications Verification Ciloprost; ZK 36374	Prostaglandin Receptor Endogenous Metabolite	Endocrinology Cancer
Iloprost (ZK 36374; Ciloprost) is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis. Iloprost can be used for peripheral vascular research .

HY-114671

Taprostene CG-4203	Prostaglandin Receptor	Cardiovascular Disease
Taprostene (CG-4203) is a synthetic, chemically stable analogue of Prostacyclin (PGI2). Taprostene exhibits endothelium and myocardial protecting actions after acute myocardial ischemia and reperfusion in cats. Taprostene enhances cytoprotective actions, while minimizing unwanted hemodynamic effects .

HY-149388

Anticancer agent 139	Microtubule/Tubulin	Cancer
Anticancer agent 139 (Compound 6h) has potent anticancer activity. Anticancer agent 139 displayed a π–cationic interaction with the residue Lys352 of Tublin. Anticancer agent 139 has good anticancer activity against SNB-19, OVCAR-8, and NCI-H40 with PGIs of 86.61, 85.26, and 75.99, respectively. Anticancer agent 139 also has moderate anticancer activity against HOP-62, SNB-75, ACHN, NCI/ADR-RES, 786-O, A549/ATCC, HCT-116, and MDA-MB-231 with PGIs of 67.55, 65.46, 59.09, 59.02, 57.88, 56.88, 56.53, 56.4, and 51.88 respectively .

HY-13569A

Beraprost sodium	Prostaglandin Receptor	Cardiovascular Disease Inflammation/Immunology
Beraprost sodium, a prostacyclin analog, is a stable and orally active proagent of *PGI2. Beraprost sodium is a potent vasodilator*, has the potential for pulmonary arterial hypertension treatment through expanding renal vessels, improving microcirculation . Beraprost (sodium) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-P2918

Phosphoglucose Isomerase, Baker's yeast (S. cerevisiae) GPI; Phosphoglucose Isomerase	Endogenous Metabolite	Others
Phosphoglucose Isomerase, Baker's yeast (S. cerevisiae) (GPI), i.e., phosphoglucose isomerase/phosphoglucoisomerase (PGI) or phosphohexose isomerase (PHI), is often used in biochemical studies. Glucose 6-phosphate isomeras is a highly conserved glycolytic and dimeric enzyme. Glucose 6-phosphate isomeras catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W011184

6-Phosphogluconic acid trisodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
6-Phosphogluconic acid trisodium is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with K_is of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite .

HY-A0096

Iloprost 3 Publications Verification Ciloprost; ZK 36374	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Endocrinology Cancer	Prostaglandin Receptor Endogenous Metabolite
Iloprost (ZK 36374; Ciloprost) is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis. Iloprost can be used for peripheral vascular research .

HY-113514

6-Phosphogluconic acid	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
6-Phosphogluconic acid is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with K_is of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid is an endogenous metabolite .

Species:	Human (1) Mouse (1)
Tag:	His (2) B2M (1)
Source:	E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P71680

	Glucose-6-phosphate isomerase Protein, Human (His) AMF; Aurocrine motility factor; Autocrine motility factor; DKFZp686C13233; EC 5.3.1.9; Neuroleukin; NLK; Oxoisomerase; PGI; PHI; Phosphoglucose isomerase; SA-36; SA36; Sperm antigen 36	Human	E. coli
	Glucose-6-phosphate isomerase protein is a key player in glycolysis, catalyzing the conversion of glucose-6-phosphate into fructose-6-phosphate in the cytoplasm. It carries out this reaction reversibly during gluconeogenesis. Glucose-6-phosphate isomerase Protein, Human (His) is the recombinant human-derived Glucose-6-phosphate isomerase protein, expressed by E. coli , with N-6*His labeled tag. The total length of Glucose-6-phosphate isomerase Protein, Human (His) is 553 a.a., with molecular weight of ~65.0 kDa.

HY-P72210

	Glucose-6-phosphate isomerase Protein, Mouse (His-B2M) Gpi; Gpi1Glucose-6-phosphate isomerase; GPI; EC 5.3.1.9; Autocrine motility factor; AMF; Neuroleukin; NLK; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI	Mouse	E. coli
	Glucose-6-phosphate isomerase protein exists in the cytoplasm and has dual functions. It converts glucose-6-phosphate into fructose-6-phosphate, playing a vital role in glycolysis and gluconeogenesis. Glucose-6-phosphate isomerase Protein, Mouse (His-B2M) is the recombinant mouse-derived Glucose-6-phosphate isomerase protein, expressed by E. coli , with N-6*His, B2M labeled tag. The total length of Glucose-6-phosphate isomerase Protein, Mouse (His-B2M) is 557 a.a., with molecular weight of ~76.6 kDa.


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Cat. No.	Product Name	Chemical Structure

HY-14870S1

Selexipag-d7

Selexipag-d₇ is the deuterium labeled Selexipag. Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin (PGI2) receptor (IP receptor)[1][2].
HY-A0096S

Iloprost-d4

Iloprost-d₄ (Ciloprost-d4) is the deuterium labeled Iloprost. Iloprost (ZK 36374) is a synthetic analogue of prostacyclin PGI2[1][2].
HY-14870S3

Selexipag-d6

Selexipag-d₆ is deuterium labeled Selexipag. Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin (PGI2) receptor (IP receptor).

Selexipag-d7
Selexipag-d₇ is the deuterium labeled Selexipag. Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin (PGI2) receptor (IP receptor)[1][2].

Iloprost-d4
Iloprost-d₄ (Ciloprost-d4) is the deuterium labeled Iloprost. Iloprost (ZK 36374) is a synthetic analogue of prostacyclin PGI2[1][2].

Selexipag-d6
Selexipag-d₆ is deuterium labeled Selexipag. Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin (PGI2) receptor (IP receptor).

Cat. No.	Product Name	Application	Reactivity

HY-P82032

AMF Antibody (YA1777) GPI; Glucose-6-phosphate isomerase; GPI; Autocrine motility factor; AMF; Neuroleukin; NLK; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI; Sperm antigen 36; SA-36	WB, IHC-P, ICC/IF, FC	Human

HY-P82562

Biglycan Antibody (YA2307)

BGN; Biglycan; DSPG1; PG S1; PGI; SEMDX; SLRR1A
WB, IP, FC Human, Mouse, Rat

HY-P83334

IGFBP7 Antibody (YA3079) IGFBP7; MAC25; PSF; Insulin-like growth factor-binding protein 7; IBP-7; IGF-binding protein 7; IGFBP-7; IGFBP-rP1; MAC25 protein; PGI2-stimulating factor; Prostacyclin-stimulating factor; Tumor-derived adhesion factor; TAF	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat

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Inhibitors & Agonists

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Isotope-Labeled Compounds

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PGI

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