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Results for "

PLX4032

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12057
    Vemurafenib
    60+ Cited Publications

    PLX4032; RG7204; RO5185426

    		 Raf Autophagy Cancer
    Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAF V600E and c-RAF-1, respectively . Vemurafenib induces cell autophagy .
    Vemurafenib
  • HY-12057S1
    Vemurafenib-d7

    PLX4032-d7; RG7204-d7; RO5185426-d7

    		 Isotope-Labeled Compounds Raf Autophagy Cancer
    Vemurafenib-d7 is deuterium labeled Vemurafenib. Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively[1][4]. Vemurafenib induces cell autophagy[5].
    Vemurafenib-d7
  • HY-12057S
    Vemurafenib-d5

    		Isotope-Labeled Compounds Raf Autophagy Cancer
    Vemurafenib-d5 is the deuterium labeled Vemurafenib. Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively[1][4]. Vemurafenib induces cell autophagy[5].
    Vemurafenib-d5

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