Search Result
Results for "
PROTAC Linkers
" in MCE Product Catalog:
3162
Inhibitors & Agonists
4
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
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- HY-130404
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- HY-130662
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- HY-130416
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- HY-130536
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- HY-130520
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- HY-133008
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- HY-113828
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- HY-W190966
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- HY-W014099
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Boc-NH-C4-acid
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PROTAC Linkers
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Cancer
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Boc-NH-C4-acid is a PROTAC linker, which belongs to a Alkyl/ether linker. Boc-NH-C4-acid can be used in the synthesis of the compound PROTAC1, and specifically degrades EED, EZH2, and SUZ12 in the PRC2 Complex.
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- HY-140204
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- HY-141399
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- HY-141222
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- HY-140057
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- HY-141400
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- HY-141408
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- HY-141224
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- HY-130589
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- HY-141398
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- HY-140360
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- HY-140398
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- HY-141403
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- HY-141376
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- HY-141401
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- HY-141219
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- HY-141223
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- HY-130507
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- HY-141221
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- HY-141375
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- HY-141402
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- HY-141396
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- HY-126948
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- HY-126950
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- HY-140056
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- HY-141112
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- HY-140284A
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- HY-140507
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- HY-124011
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- HY-130641
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Br-C10-methyl ester
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PROTAC Linkers
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Cancer
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Br-C10-methyl ester is a PROTAC linker, which refers to the alkyl/ether composition. Br-C10-methyl ester is used in the synthesis of a series of PROTACs (MS432). PROTACs contain two different ligands connected by a linker; one is the VHL ligand portion and the other is for the target protein.
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- HY-108368
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- HY-140164
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- HY-140001
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- HY-130568
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- HY-135796
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- HY-140594
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- HY-140809
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- HY-140590
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- HY-141407
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- HY-130619
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Boc-C1-PEG3-C4-OBn
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PROTAC Linkers
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Cancer
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Boc-C1-PEG3-C4-OBn (PROTAC Linker 15) is a PROTAC linker, which refers to the PEG composition. Boc-C1-PEG3-C4-OBn can be used in the synthesis of a series of PROTACs, such as PROTAC SGK3 degrader-1 (HY-125878). PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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- HY-130228
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- HY-42745
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m-PEG2-Tos
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ADC Linkers
PROTAC Linkers
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Cancer
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m-PEG2-Tos is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG2-Tos is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-130598
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- HY-42617
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- HY-140828
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m-PEG4-azide
13-Azido-2,5,8,11-tetraoxatridecane
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PROTAC Linkers
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Cancer
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m-PEG4-azide (13-Azido-2,5,8,11-tetraoxatridecane) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-130599
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- HY-22340
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- HY-W016735
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- HY-W067489
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- HY-130334
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- HY-126959
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- HY-133176
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- HY-126962
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- HY-126887
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- HY-126961
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- HY-126963
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- HY-40178
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NH2-C4-NH-Boc
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PROTAC Linkers
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Cancer
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NH2-C4-NH-Boc (compound 15) is a PROTAC linker, which refers to the Alkyl/ether composition. NH2-C4-NH-Boc can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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- HY-W039197
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- HY-23167
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- HY-130291
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- HY-133009
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- HY-130586
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- HY-130290
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- HY-135179
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- HY-133175
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- HY-126957
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- HY-133174
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- HY-130560
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- HY-120781
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- HY-140074
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- HY-140077
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- HY-130330
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- HY-126886
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Mal-PEG1-NHS ester
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ADC Linkers
PROTAC Linkers
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Cancer
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Mal-PEG1-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG1-NHS ester is PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-W016087
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Monoethyl pimelate
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PROTAC Linkers
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Cancer
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Monoethyl pimelate is a PROTAC linker, which refers to the alkyl/ether composition. Monoethyl pimelate can be used in the synthesis of (S,R,S)-AHPC-Me-C7 ester, a specific BCL-XL PROTAC degrader.
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- HY-W008296
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NH2-C6-NH-Boc
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PROTAC Linkers
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Cancer
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NH2-C6-NH-Boc is a PROTAC linker which refers to the alkyl/ether composition. NH2-C6-NH-Boc can be used in the synthesis the Mcl-1 inhibitor based on PROTAC.
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- HY-140455
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- HY-140067
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- HY-140802
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- HY-133061
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- HY-140217
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- HY-122459
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- HY-140801
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- HY-140218
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- HY-122456
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- HY-140759
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- HY-126882
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- HY-130715
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tert-Butyl 11-aminoundecanoate
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PROTAC Linkers
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Cancer
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tert-Butyl 11-aminoundecanoate (compound 6b) is a PROTAC linker, which refers to the PEG composition. tert-Butyl 11-aminoundecanoate can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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- HY-120918
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NH2-PEG7
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PROTAC Linkers
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Cancer
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NH2-PEG7 is a PROTAC linker, which refers to the PEG composition. NH2-PEG7 can be used in the synthesis of the PROTAC PARP1 degrader iRucaparib-AP6.
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- HY-117519
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- HY-W043277
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- HY-133006
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- HY-141406
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- HY-140239
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- HY-130742
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- HY-130420
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- HY-35261A
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- HY-W067061
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Hydroxy-PEG2-(CH2)2-Boc
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ADC Linkers
PROTAC Linkers
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Cancer
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Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196). Hydroxy-PEG2-(CH2)2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-130490
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- HY-130143
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- HY-W010764
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- HY-130197
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- HY-118764
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Propargyl-PEG2-acid
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ADC Linkers
PROTAC Linkers
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Cancer
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Propargyl-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-117104
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Hydroxy-PEG4-acid
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ADC Linkers
PROTAC Linkers
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Cancer
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Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-140501
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m-PEG11-acid
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ADC Linkers
PROTAC Linkers
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Cancer
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m-PEG11-acid is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG11-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-140500
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m-PEG10-acid
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ADC Linkers
PROTAC Linkers
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Cancer
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m-PEG10-acid is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG10-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-141404
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- HY-141395
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m-PEG4-Boc
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ADC Linkers
PROTAC Linkers
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Cancer
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m-PEG4-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG4-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-21577
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- HY-140811
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Azido-PEG3-maleimide
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PROTAC Linkers
ADC Linkers
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Cancer
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Azido-PEG3-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG3-maleimide is also a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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- HY-126888
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- HY-140215
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Azido-PEG6-amine
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PROTAC Linkers
ADC Linkers
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Cancer
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Azido-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG6-amine is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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- HY-140226
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m-PEG10-amine
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ADC Linkers
PROTAC Linkers
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Cancer
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m-PEG10-amine is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG10-amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-126951
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Aminooxy-PEG2-alcohol
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ADC Linkers
PROTAC Linkers
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Cancer
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Aminooxy-PEG2-alcohol is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Aminooxy-PEG2-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-140004
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Azide-PEG3-Tos
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PROTAC Linkers
ADC Linkers
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Cancer
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Azide-PEG3-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azide-PEG3-Tos is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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- HY-113931
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Aminooxy-PEG2-azide
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PROTAC Linkers
ADC Linkers
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Cancer
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Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Aminooxy-PEG2-azide is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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- HY-130211
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Azido-PEG5-alcohol
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ADC Linkers
PROTAC Linkers
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Cancer
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Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-141220
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m-PEG12-OH
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PROTAC Linkers
ADC Linkers
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Cancer
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m-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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- HY-140227
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m-PEG12-amine
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PROTAC Linkers
ADC Linkers
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Cancer
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m-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG12-amine is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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- HY-124123
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Aminooxy-PEG4-alcohol
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ADC Linkers
PROTAC Linkers
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Cancer
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Aminooxy-PEG4-alcohol is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Aminooxy-PEG4-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-120775
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- HY-140406
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- HY-140596
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- HY-130695
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- HY-130549
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Acid-PEG3-C2-Boc
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PROTAC Linkers
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Cancer
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Acid-PEG3-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the degradation of EGFR and inhibition of mTOR.
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- HY-120773
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- HY-126881
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- HY-130077
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- HY-130442
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Mal-PEG2-acid
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ADC Linkers
PROTAC Linkers
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Cancer
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Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule. Mal-PEG2-acid is also a PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-140150
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Azido-PEG3-Val-Cit-PAB-PNP
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ADC Linkers
PROTAC Linkers
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Cancer
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Azido-PEG3-Val-Cit-PAB-PNP is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG3-Val-Cit-PAB-PNP is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-140149
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Azido-PEG4-Val-Cit-PAB-OH
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ADC Linkers
PROTAC Linkers
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Cancer
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Azido-PEG4-Val-Cit-PAB-OH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG4-Val-Cit-PAB-OH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-126949
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Aminooxy-PEG3-azide
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ADC Linkers
PROTAC Linkers
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Cancer
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Aminooxy-PEG3-azide is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Aminooxy-C2-PEG3-azide is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-141218
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m-PEG10-alcohol
Decaethylene glycol monomethyl ether
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ADC Linkers
PROTAC Linkers
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Cancer
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m-PEG10-alcohol (Decaethylene glycol monomethyl ether) is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG10-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-117186
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Bis-propargyl-PEG6
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PROTAC Linkers
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Metabolic Disease
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Bis-propargyl-PEG6 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG6 can be used to synthesize the polymer linked multimers of guanosine-3', 5'-cyclic monophosphates.
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- HY-133190
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Bis-propargyl-PEG7
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PROTAC Linkers
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Metabolic Disease
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Bis-propargyl-PEG7 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG7 can be used to synthesize the polymer linked multimers of guanosine-3', 5'-cyclic monophosphates.
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- HY-23408
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Tos-PEG3
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PROTAC Linkers
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Cancer
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Tos-PEG3 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
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- HY-130312
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- HY-130693
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- HY-108369
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Azido-PEG1-CH2CO2H
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PROTAC Linkers
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Cancer
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Azido-PEG1-CH2CO2H is a PROTAC linker, which refers to the alkyl/ether composition. Azido-PEG1-CH2CO2H can be used in the synthesis of PROTAC BRD4 Degrader-1.
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- HY-W013253
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- HY-130194
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Azido-PEG5-CH2CO2H
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ADC Linkers
PROTAC Linkers
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Cancer
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Azido-PEG5-CH2CO2H is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-CH2CO2H is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-141159
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- HY-112559
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- HY-141160
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- HY-141161
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- HY-120587
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- HY-126891
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- HY-141162
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- HY-140015
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- HY-133191
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- HY-141178
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- HY-141181
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- HY-133049
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- HY-130382
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- HY-141187
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- HY-41921
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- HY-141166
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- HY-141183
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- HY-130374
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- HY-133229
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- HY-141180
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- HY-130375
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- HY-126977
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- HY-141189
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- HY-141179
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- HY-141177
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- HY-141169
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- HY-130378
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- HY-130584
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- HY-130380
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- HY-130384
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- HY-141188
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- HY-141168
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- HY-133189
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- HY-139661
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- HY-130146
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- HY-133192
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Bis-propargyl-PEG3
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PROTAC Linkers
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Cancer
Infection
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Bis-propargyl-PEG3 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG3 is used in the synthesis of zinc-dipicolylamine (ZnDPA) complexes with antiplasmodial activity .
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- HY-135090
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m-PEG8-Tos
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PROTAC Linkers
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Cancer
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Tos-PEG8-m is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-d). Tos-PEG8-m is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277).
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- HY-130554
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- HY-133230
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- HY-130147
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- HY-117045
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- HY-114670
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- HY-130373
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-
- HY-113921
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-
- HY-131184
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- HY-130563
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- HY-130770
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- HY-130820
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- HY-130389
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- HY-115414
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- HY-130537
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Azido-PEG6-alcohol
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PROTAC Linkers
ADC Linkers
|
Cancer
|
Azido-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG6-alcohol is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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- HY-130474
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Azido-PEG6-NHS ester
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG6-NHS ester is also a PEG- and Alkyl/ether based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-130184
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Azido-PEG8-NHS ester
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ADC Linkers
PROTAC Linkers
|
Cancer
|
Azido-PEG8-NHS ester is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG8-NHS ester is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-121507
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-
- HY-130137
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-
- HY-130422
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Tos-PEG4-t-butyl ester
Tos-PEG4-Boc
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PROTAC Linkers
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Cancer
|
Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker, which refers to the PEG composition. Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) can be used in the synthesis of a series of PROTACs, such as BI-3663 (HY-111546). BI-3663 is a highly selective PTK2/FAK PROTAC, with cereblon ligands to hijack E3 ligases for PTK2 degradation, and inhibits PTK2 with an IC50 of 18 nM.
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- HY-130620
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PEG3-C4-OBn
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PROTAC Linkers
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Cancer
|
PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. PEG3-C4-OBn can be used in the synthesis of the PROTAC SGK3 degrader-1 (HY-125878). PROTAC SGK3 degrader-1 is a potent SKG3 degrader based on PROTAC.
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- HY-130390
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- HY-42618
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Azido-PEG4-CH2-Boc
|
ADC Linkers
PROTAC Linkers
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Cancer
|
Azido-PEG4-CH2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG4-CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-130821
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- HY-130819
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- HY-114661
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m-PEG4-Tos
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PROTAC Linkers
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Cancer
|
m-PEG4-Tos is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-b). m-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277).
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- HY-W042501
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m-PEG5-Tos
|
PROTAC Linkers
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Cancer
|
m-PEG5-Tos is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-c). m-PEG5-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277).
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-
- HY-130407
-
Lipoamido-PEG3-OH
|
PROTAC Linkers
|
Cancer
|
Lipoamido-PEG3-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Lipoamido-PEG3-OH (compound TA-TEG-G2CN) can be used in the formation of a highly stable, dendronized gold nanoparticle (AuNP)-based drug delivery platform.
|
-
- HY-130711A
-
(S,R,S)-AHPC-C3-NH2 TFA
VH032-C3-NH2 TFA
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
(S,R,S)-AHPC-C3-NH2 TFA (VH032-C3-NH2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the synthesis of a series of PROTACs, such as UNC6852 (HY-130708). UNC6852 is an EED-targeted bivalent chemical degrader.
|
-
- HY-130711
-
(S,R,S)-AHPC-C3-NH2
VH032-C3-NH2
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the synthesis of a series of PROTACs, such as UNC6852 (HY-130708). UNC6852 is an EED-targeted bivalent chemical degrader.
|
-
- HY-42489
-
N3-PEG3-CH2CH2-Boc
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
N3-PEG3-CH2CH2-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-CH2CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-133699
-
Pomalidomide-PEG4-COOH
|
Ligands for E3 Ligase
|
Others
|
Pomalidomide-PEG4-COOH is a E3 ligase ligand-linker conjugate. Pomalidomide-PEG4-COOH contains the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology (extracted from patent WO2017184995A1).
|
-
- HY-140345A
-
L-Homopropargylglycine hydrochloride
|
PROTAC Linkers
|
Cancer
|
L-Homopropargylglycine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-homopropargylglycine hydrochloride is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor.
|
-
- HY-140345
-
L-Homopropargylglycine
|
PROTAC Linkers
|
Cancer
|
L-Homopropargylglycine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-homopropargylglycine is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor.
|
-
- HY-118808
-
-
- HY-126976
-
-
- HY-W051634
-
-
- HY-126894
-
Bis-PEG9-acid
|
PROTAC Linkers
ADC Linkers
|
Cancer
|
Bis-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG9-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-126893
-
Bis-PEG8-acid
|
PROTAC Linkers
ADC Linkers
|
Cancer
|
Bis-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-130982
-
Lenalidomide-PEG3-iodine
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
Lenalidomide-PEG3-iodine is a synthesized E3 ligase ligand-linker conjugate that incorporates the Lenalidomide based cereblon ligand and a 3-unit PEG linker. Lenalidomide-PEG3-iodine can be used in the synthesis of a series of PROTACs, such as SJF620 (HY-133137). SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM.
|
-
- HY-126892
-
Bis-PEG7-acid
|
PROTAC Linkers
ADC Linkers
|
Cancer
|
Bis-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-130408
-
m-PEG6-Amine
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
m-PEG6-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG6-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-W018174
-
m-PEG3-Amine
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
m-PEG3-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-140310
-
TCO-PEG4-DBCO
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
TCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-130410
-
-
- HY-130387
-
-
- HY-126885
-
DBCO-PEG5-NHS ester
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-130683
-
-
- HY-145177
-
Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc can be used for the synthesis of PROTAC BET degrader. (From patent WO2017180417A1 compound s7).
|
-
- HY-130682
-
-
- HY-133044
-
Boc-Pip-alkyne-Ph-COOH
|
PROTAC Linkers
|
Cancer
|
Boc-Pip-alkyne-Ph-COOH is a PROTAC linker, which refers to the alkyl/ether composition. Boc-Pip-alkyne-Ph-COOH can be used in the synthesis of a series of PROTACs, such as ARD-266 (HY-133020). ARD-266 effectively induces degradation of androgen receptor (AR) protein in AR-positive LNCaP, VCaP, and 22Rv1 prostate cancer cell lines with DC50 values of 0.2-1 nM.
|
-
- HY-133799
-
-
- HY-W017440
-
-
- HY-W018745
-
-
- HY-W004896
-
-
- HY-W004816
-
-
- HY-W017772
-
-
- HY-W025896
-
-
- HY-W018745S
-
Tetraethylene glycol-d8
PROTAC Linker 18-d8
|
PROTAC Linkers
|
Cancer
|
Tetraethylene glycol-d8 (PROTAC Linker 18-d8) is the deuterium labeled Tetraethylene glycol. Tetraethylene glycol (PROTAC Linker 18) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-128803
-
-
- HY-125907
-
-
- HY-128805
-
-
- HY-125842
-
-
- HY-128833
-
-
- HY-125906
-
-
- HY-132991
-
ML 2-14
|
PROTAC Linkers
|
Others
|
ML 2-14 is a PROTAC linker, which belongs to a polyethylene glycol (PEG) linker. ML 2-14 can be used in the synthesis of the PROTAC.
|
-
- HY-130845
-
AR antagonist 1
|
Ligands for E3 Ligase
|
Cancer
|
AR antagonist 1 (compound 29) is a potent androgen receptor (AR) antagonist and binds to E3 ligase ligands with weak binding affinities to VHL protein in the synthesis of PROTAC ARD-266 (HY-133020).
|
-
- HY-W007545
-
NH2-PEG3
PROTAC Linker 35
|
PROTAC Linkers
|
Cancer
|
NH2-PEG3 (PROTAC Linker 35) is a PROTAC linker, which belongs to a polyethylene glycol (PEG) linker. NH2-PEG3 (PROTAC Linker 35) can be used in the synthesis of the PROTAC (β-NF-JQ1).
|
-
- HY-116006
-
Bis-PEG5-acid
PROTAC Linker 36
|
PROTAC Linkers
|
Cancer
|
Bis-PEG5-acid (PROTAC Linker 36) is a PROTAC linker, which belongs to a polyethylene glycol (PEG) linker. Bis-PEG5-acid (PROTAC Linker 36) can be used in the synthesis of the CP5V. CP5V is a PROTAC, and specifically degrades Cdc20.
|
-
- HY-40171
-
-
- HY-125844
-
-
- HY-W004710
-
-
- HY-125888
-
-
- HY-126313
-
-
- HY-128844
-
-
- HY-128801
-
-
- HY-42637
-
-
- HY-W008474
-
-
- HY-128835
-
-
- HY-108371
-
-
- HY-W022240
-
-
- HY-42776
-
-
- HY-W140896
-
-
- HY-126916
-
-
- HY-128802
-
-
- HY-128834
-
-
- HY-128931
-
-
- HY-128847
-
-
- HY-125887
-
-
- HY-141233
-
-
- HY-W007341
-
-
- HY-130458
-
EGNHS
EGS crosslinker
|
PROTAC Linkers
|
Cancer
|
EGNHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-141232
-
-
- HY-138749
-
-
- HY-141263
-
-
- HY-W050087
-
-
- HY-143820
-
-
- HY-124476
-
-
- HY-141230
-
-
- HY-116899
-
-
- HY-141231
-
-
- HY-130292
-
-
- HY-W096085
-
-
- HY-W096121
-
-
- HY-134751
-
-
- HY-43614
-
-
- HY-W034918
-
Docosanedioic acid
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
Docosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Docosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-141260
-
-
- HY-124480
-
-
- HY-119343
-
-
- HY-141186
-
-
- HY-140338
-
-
- HY-143819
-
-
- HY-130888
-
-
- HY-124318
-
-
- HY-W067705
-
-
- HY-140341
-
-
- HY-140346
-
-
- HY-140339
-
-
- HY-D1295
-
-
- HY-W040304
-
-
- HY-140335
-
-
- HY-134719
-
-
- HY-130887
-
-
- HY-W019795
-
-
- HY-123916
-
-
- HY-141293
-
-
- HY-141165
-
-
- HY-141175
-
-
- HY-130893
-
-
- HY-141176
-
-
- HY-140346A
-
-
- HY-138467
-
-
- HY-W004945
-
-
- HY-129938
-
-
- HY-126908
-
-
- HY-W096096
-
-
- HY-130908
-
-
- HY-141186A
-
-
- HY-130283
-
-
- HY-140293
-
-
- HY-22393
-
-
- HY-127056
-
-
- HY-W190971
-
-
- HY-138401
-
-
- HY-134746
-
-
- HY-113336B
-
-
- HY-138461
-
-
- HY-120175
-
-
- HY-140280
-
-
- HY-W076543
-
-
- HY-140329
-
-
- HY-136168
-
-
- HY-133404
-
-
- HY-W042657
-
-
- HY-42145
-
-
- HY-W018365
-
-
- HY-W044459
-
-
- HY-132065
-
-
- HY-134695
-
-
- HY-138409
-
-
- HY-140357
-
-
- HY-W096150
-
-
- HY-77959
-
-
- HY-140343
-
-
- HY-140991
-
-
- HY-140208
-
-
- HY-141136
-
-
- HY-W042713
-
-
- HY-124531
-
-
- HY-W142506
-
-
- HY-141128
-
-
- HY-140947
-
-
- HY-130898
-
BM-PEG3
1,11-Bis-maleimidotetraethyleneglycol
|
PROTAC Linkers
|
Cancer
|
BM-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-140328
-
-
- HY-W037355
-
-
- HY-W007853
-
-
- HY-W018464
-
-
- HY-W096158
-
-
- HY-W042625
-
-
- HY-141268
-
-
- HY-W125504
-
AEEA-AEEA
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
AEEA-AEEA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). AEEA-AEEA is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-76043
-
H-Hyp-OMe hydrochloride
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
H-Hyp-OMe hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). H-Hyp-OMe hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]<
|
-
- HY-W010975
-
Fmoc-Lys-OH hydrochloride
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
Fmoc-Lys-OH hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Lys-OH hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-130186
-
-
- HY-135820
-
-
- HY-140408
-
-
- HY-140179
-
-
- HY-132012
-
-
- HY-140281
-
-
- HY-140318
-
-
- HY-141099
-
-
- HY-133051
-
-
- HY-140496
-
-
- HY-140651
-
-
- HY-140695
-
-
- HY-140642
-
-
- HY-140652
-
-
- HY-138393
-
-
- HY-140367
-
-
- HY-140655
-
-
- HY-133050
-
-
- HY-130425
-
-
- HY-140549
-
-
- HY-141026
-
-
- HY-133386
-
-
- HY-W096116
-
-
- HY-140038
-
-
- HY-140020
-
-
- HY-140548
-
-
- HY-141332
-
-
- HY-133334
-
-
- HY-140657
-
-
- HY-140692
-
-
- HY-141267
-
-
- HY-135153
-
-
- HY-141021
-
-
- HY-138379
-
-
- HY-133054
-
-
- HY-133377
-
-
- HY-141354
-
-
- HY-140717
-
-
- HY-140962
-
-
- HY-140741
-
-
- HY-140334
-
-
- HY-113924
-
-
- HY-140697
-
-
- HY-140183
-
-
- HY-120368
-
-
- HY-141027
-
-
- HY-W096086
-
-
- HY-133481
-
-
- HY-23166
-
-
- HY-W004447
-
-
- HY-133306
-
-
- HY-140661
-
-
- HY-140184
-
-
- HY-133308
-
-
- HY-130417
-
-
- HY-130896
-
-
- HY-140696
-
-
- HY-140674
-
-
- HY-140731
-
-
- HY-140547
-
-
- HY-140709
-
-
- HY-141020
-
-
- HY-140322
-
-
- HY-141334
-
-
- HY-W096129
-
-
- HY-130857
-
-
- HY-132078
-
-
- HY-140666
-
-
- HY-133406
-
-
- HY-140703
-
-
- HY-132098
-
-
- HY-141022
-
-
- HY-43055
-
-
- HY-133318
-
-
- HY-140690
-
-
- HY-W190901
-
-
- HY-140996
-
-
- HY-140716
-
-
- HY-140411
-
-
- HY-130555
-
-
- HY-138487
-
-
- HY-W096089
-
-
- HY-140707
-
-
- HY-140660
-
-
- HY-140672
-
-
- HY-140499
-
-
- HY-140649
-
-
- HY-140182
-
-
- HY-140740
-
-
- HY-140176
-
-
- HY-23417
-
-
- HY-141264
-
-
- HY-141266
-
-
- HY-140265
-
-
- HY-140641
-
-
- HY-140953
-
-
- HY-W035417
-
-
- HY-132075
-
-
- HY-141363
-
-
- HY-140656
-
-
- HY-140673
-
-
- HY-138763
-
-
- HY-140268
-
-
- HY-140667
-
-
- HY-138455
-
-
- HY-42569
-
-
- HY-140185
-
-
- HY-143815
-
-
- HY-140018
-
-
- HY-141019
-
-
- HY-141352
-
-
- HY-140654
-
-
- HY-140721
-
-
- HY-140704
-
-
- HY-140648
-
-
- HY-124380
-
-
- HY-140409
-
-
- HY-140683
-
-
- HY-140700
-
-
- HY-140332
-
-
- HY-140693
-
-
- HY-140348
-
-
- HY-140638
-
-
- HY-140267
-
-
- HY-140161
-
-
- HY-140407
-
-
- HY-130542
-
-
- HY-140653
-
-
- HY-130904
-
-
- HY-140509
-
-
- HY-140153
-
-
- HY-138435
-
-
- HY-140723
-
-
- HY-133052
-
-
- HY-141023
-
-
- HY-W010948
-
-
- HY-140713
-
-
- HY-141393
-
-
- HY-140994
-
-
- HY-W013731
-
-
- HY-140388
-
-
- HY-140178
-
-
- HY-140659
-
-
- HY-138524
-
-
- HY-140495
-
-
- HY-141024
-
-
- HY-141383
-
-
- HY-133385
-
-
- HY-140177
-
-
- HY-140735
-
-
- HY-140640
-
-
- HY-140718
-
-
- HY-140684
-
-
- HY-140021
-
-
- HY-133384
-
-
- HY-141326
-
-
- HY-140682
-
-
- HY-140394
-
-
- HY-140665
-
-
- HY-140320
-
-
- HY-140269
-
-
- HY-140720
-
-
- HY-140410
-
-
- HY-140186
-
-
- HY-140929
-
-
- HY-130909
-
-
- HY-138764
-
-
- HY-133425
-
-
- HY-W190962
-
-
- HY-141164
-
-
- HY-130198
-
-
- HY-140494
-
-
- HY-132027
-
-
- HY-140995
-
-
- HY-140333
-
-
- HY-140708
-
-
- HY-140457
-
-
- HY-140734
-
-
- HY-133290
-
-
- HY-133324
-
-
- HY-132015
-
-
- HY-133323
-
-
- HY-140662
-
-
- HY-140502
-
-
- HY-120678
-
-
- HY-140639
-
-
- HY-141333
-
-
- HY-140694
-
-
- HY-140705
-
-
- HY-136159
-
-
- HY-140041
-
-
- HY-138486
-
-
- HY-140699
-
-
- HY-140702
-
-
- HY-130938
-
-
- HY-140458
-
-
- HY-140358
-
-
- HY-140330
-
-
- HY-140663
-
-
- HY-132091
-
-
- HY-140724
-
-
- HY-140646
-
-
- HY-130895
-
-
- HY-141335
-
-
- HY-140685
-
-
- HY-132088
-
-
- HY-140368
-
-
- HY-W096147
-
-
- HY-43581
-
-
- HY-140710
-
-
- HY-140691
-
-
- HY-140180
-
-
- HY-140993
-
-
- HY-140040
-
-
- HY-W096166
-
-
- HY-140706
-
-
- HY-W096131
-
-
- HY-140698
-
-
- HY-140395
-
-
- HY-133322
-
-
- HY-141265
-
-
- HY-140650
-
-
- HY-141025
-
-
- HY-W096155
-
-
- HY-140715
-
-
- HY-140670
-
-
- HY-138507
-
-
- HY-140319
-
-
- HY-133231
-
-
- HY-141163
-
-
- HY-140000
-
-
- HY-140005
-
-
- HY-130213
-
-
- HY-140321
-
-
- HY-140266
-
-
- HY-140022
-
-
- HY-138436
-
-
- HY-140181
-
-
- HY-140453
-
-
- HY-133291
-
-
- HY-140658
-
-
- HY-140421
-
-
- HY-138411
-
-
- HY-140736
-
-
- HY-133307
-
-
- HY-W096160
-
-
- HY-140714
-
-
- HY-138723
-
-
- HY-140456
-
-
- HY-133317
-
-
- HY-138505
-
-
- HY-140664
-
-
- HY-140671
-
-
- HY-140719
-
-
- HY-133325
-
-
- HY-140647
-
-
- HY-W096142
-
-
- HY-W096161
-
-
- HY-140039
-
-
- HY-134754
-
-
- HY-140689
-
-
- HY-101838
-
dBET1
|
PROTACs
Epigenetic Reader Domain
|
Cancer
|
dBET1 is a PROTAC connected by ligands for Cereblon and BRD4 with an EC50 of 430 nM. dBET1 is a PROTAC that composes of (+)-JQ1 (HY-13030) linked to NSC 527179 (HY-14658) with a linker.
|
-
- HY-65039
-
Boc-Hyp-OMe
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
Boc-Hyp-OMe is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OMe is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-I0781
-
Boc-Hyp-OH
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
Boc-Hyp-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]
|
-
- HY-W018154
-
H-Glu-OtBu
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
H-Glu-OtBu is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). H-Glu-OtBu is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2
|
-
- HY-129652
-
Halo PROTAC 1
|
AUTACs
|
Cancer
|
Halo PROTAC 1 is a conjugate of ligands for E3 and 22-atom-length linker. The connector of linker is Halogen group. Halo PROTAC 1 is a ligand having activity to bind to an intracellular proteins fused with HaloTag and a structure having activity to induce autophagy of an intracellular molecule are linked via a PEG linker. Halo PROTAC 1 can be uesd for the synthesis of AUTAC.
|
-
- HY-120430
-
-
- HY-140722
-
-
- HY-133493
-
-
- HY-140784
-
-
- HY-140516
-
-
- HY-140756
-
-
- HY-141368
-
-
- HY-140852
-
-
- HY-133279
-
-
- HY-138354
-
-
- HY-140450
-
-
- HY-134710
-
-
- HY-133354
-
-
- HY-133394
-
-
- HY-140387
-
-
- HY-140156
-
-
- HY-133345
-
-
- HY-143844
-
-
- HY-123629
-
-
- HY-140984
-
-
- HY-140775
-
-
- HY-133399
-
-
- HY-130534
-
-
- HY-140272
-
-
- HY-140162
-
-
- HY-140197
-
-
- HY-133395
-
-
- HY-132049
-
-
- HY-132097
-
-
- HY-135142
-
-
- HY-134752
-
-
- HY-140933
-
-
- HY-141174
-
-
- HY-138352
-
-
- HY-120724
-
-
- HY-140302
-
-
- HY-135917
-
-
- HY-132052
-
-
- HY-140957
-
-
- HY-138385
-
-
- HY-133393
-
-
- HY-141298
-
-
- HY-141367
-
-
- HY-141302
-
-
- HY-134698
-
-
- HY-140365
-
-
- HY-138449
-
-
- HY-138513
-
-
- HY-140857
-
-
- HY-133327
-
-
- HY-130600
-
-
- HY-140615
-
-
- HY-138347
-
-
- HY-138324
-
-
- HY-140036
-
-
- HY-W096069
-
-
- HY-130834
-
-
- HY-134711
-
-
- HY-138428
-
-
- HY-140618
-
-
- HY-133495
-
-
- HY-140305
-
-
- HY-126919
-
-
- HY-132070
-
-
- HY-141258
-
-
- HY-140058
-
-
- HY-130830
-
-
- HY-132095
-
-
- HY-138515
-
-
- HY-140946
-
-
- HY-140965
-
-
- HY-138518
-
-
- HY-140029
-
-
- HY-133278
-
-
- HY-140842
-
-
- HY-132053
-
-
- HY-133319
-
-
- HY-140861
-
-
- HY-140876
-
-
- HY-140963
-
-
- HY-140742
-
-
- HY-W096078
-
-
- HY-140955
-
-
- HY-140862
-
-
- HY-138382
-
-
- HY-140975
-
-
- HY-133494
-
-
- HY-W044155
-
-
- HY-130901
-
-
- HY-140823
-
-
- HY-132014
-
-
- HY-140362
-
-
- HY-141109
-
-
- HY-143827
-
-
- HY-140958
-
-
- HY-140954
-
-
- HY-138490
-
-
- HY-140396
-
-
- HY-W007529
-
-
- HY-138503
-
-
- HY-138738
-
-
- HY-141337
-
-
- HY-138325
-
-
- HY-140601
-
-
- HY-140165
-
-
- HY-140206
-
-
- HY-133300
-
-
- HY-133289
-
-
- HY-140779
-
-
- HY-W096073
-
-
- HY-138525
-
-
- HY-141357
-
-
- HY-140283
-
-
- HY-140973
-
-
- HY-138437
-
-
- HY-141272
-
-
- HY-140806
-
-
- HY-135169
-
-
- HY-138482
-
-
- HY-141394
-
-
- HY-140807
-
-
- HY-133344
-
-
- HY-W096075
-
-
- HY-141271
-
-
- HY-141106
-
-
- HY-141269
-
-
- HY-141369
-
-
- HY-140971
-
-
- HY-140399
-
-
- HY-130336
-
-
- HY-140863
-
-
- HY-130942
-
-
- HY-138722
-
-
- HY-140822
-
-
- HY-130469
-
-
- HY-141206
-
-
- HY-141366
-
-
- HY-140782
-
-
- HY-133299
-
-
- HY-130672
-
-
- HY-W096081
-
-
- HY-132068
-
-
- HY-140832
-
-
- HY-133437
-
-
- HY-140829
-
-
- HY-130890
-
-
- HY-140381
-
-
- HY-133298
-
-
- HY-140777
-
-
- HY-138342
-
-
- HY-138334
-
-
- HY-138337
-
-
- HY-W096072
-
-
- HY-140620
-
-
- HY-133294
-
-
- HY-134697
-
-
- HY-133496
-
-
- HY-141373
-
-
- HY-138477
-
-
- HY-141100
-
-
- HY-130512
-
-
- HY-W096120
-
-
- HY-140028
-
-
- HY-138391
-
-
- HY-140617
-
-
- HY-138424
-
-
- HY-133383
-
-
- HY-135940
-
-
- HY-141255
-
-
- HY-135819
-
-
- HY-140799
-
-
- HY-132021
-
-
- HY-140171
-
-
- HY-143855
-
-
- HY-140826
-
-
- HY-141093
-
-
- HY-140273
-
-
- HY-140285
-
-
- HY-141217
-
-
- HY-133352
-
-
- HY-W040527
-
-
- HY-W096157
-
-
- HY-141236
-
-
- HY-140951
-
-
- HY-140440
-
-
- HY-140059
-
-
- HY-140765
-
-
- HY-W096153
-
-
- HY-140744
-
-
- HY-138346
-
-
- HY-138483
-
-
- HY-133378
-
-
- HY-141282
-
-
- HY-140833
-
-
- HY-132104
-
-
- HY-140037
-
-
- HY-134700
-
-
- HY-140771
-
-
- HY-134720
-
-
- HY-133351
-
-
- HY-132048
-
-
- HY-130342
-
-
- HY-140751
-
-
- HY-140989
-
-
- HY-140909
-
-
- HY-140355
-
-
- HY-141101
-
-
- HY-135941
-
-
- HY-138323
-
-
- HY-138333
-
-
- HY-140282
-
-
- HY-140758
-
-
- HY-140008
-
-
- HY-140065
-
-
- HY-140733
-
-
- HY-138468
-
-
- HY-140983
-
-
- HY-130152
-
-
- HY-133295
-
-
- HY-133329
-
-
- HY-140284
-
-
- HY-138395
-
-
- HY-144081
-
-
- HY-133382
-
-
- HY-140904
-
-
- HY-133475
-
-
- HY-138739
-
-
- HY-W096077
-
-
- HY-140240
-
-
- HY-126717
-
-
- HY-140263
-
-
- HY-141238
-
-
- HY-132013
-
-
- HY-140200
-
-
- HY-140006
-
-
- HY-140616
-
-
- HY-130910
-
-
- HY-140210
-
-
- HY-141203
-
-
- HY-132114
-
-
- HY-133348
-
-
- HY-141096
-
-
- HY-133281
-
-
- HY-138472
-
-
- HY-130216
-
-
- HY-140303
-
-
- HY-140804
-
-
- HY-W096139
-
-
- HY-133277
-
-
- HY-138741
-
-
- HY-138744
-
-
- HY-133282
-
-
- HY-140913
-
-
- HY-133353
-
-
- HY-134683
-
-
- HY-133297
-
-
- HY-138721
-
-
- HY-140505
-
-
- HY-141159A
-
-
- HY-W190795
-
-
- HY-133438
-
-
- HY-132043
-
-
- HY-140175
-
-
- HY-140830
-
-
- HY-140351
-
-
- HY-141275
-
-
- HY-W042579
-
-
- HY-141204
-
-
- HY-133212
-
-
- HY-140749
-
-
- HY-133287
-
-
- HY-140754
-
-
- HY-134676
-
-
- HY-138499
-
-
- HY-140219
-
-
- HY-133498
-
-
- HY-140511
-
-
- HY-134703
-
-
- HY-138338
-
-
- HY-140898
-
-
- HY-140451
-
-
- HY-132018
-
-
- HY-133316
-
-
- HY-140382
-
-
- HY-133390
-
-
- HY-132115
-
-
- HY-130399
-
-
- HY-135049
-
-
- HY-134704
-
-
- HY-140772
-
-
- HY-138737
-
-
- HY-140278
-
-
- HY-132055
-
-
- HY-133284
-
-
- HY-140373
-
-
- HY-141171
-
-
- HY-133389
-
-
- HY-133330
-
-
- HY-141083
-
-
- HY-141082
-
-
- HY-141270
-
-
- HY-138378
-
-
- HY-134722
-
-
- HY-141338
-
-
- HY-138727
-
-
- HY-W190970
-
-
- HY-141328
-
-
- HY-141262
-
-
- HY-W143484
-
-
- HY-132085
-
-
- HY-117028
-
-
- HY-140370
-
-
- HY-138450
-
-
- HY-141308
-
-
- HY-132092
-
-
- HY-126917
-
-
- HY-140461
-
-
- HY-141226
-
-
- HY-138498
-
-
- HY-141318
-
-
- HY-132009
-
-
- HY-138531
-
-
- HY-133456
-
-
- HY-138426
-
-
- HY-140412
-
-
- HY-133439
-
-
- HY-130891
-
-
- HY-140752
-
-
- HY-140317
-
-
- HY-133276
-
-
- HY-135924
-
-
- HY-140743
-
-
- HY-132072
-
-
- HY-141184
-
-
- HY-141173
-
-
- HY-135921
-
-
- HY-W019794
-
-
- HY-140199
-
-
- HY-138423
-
-
- HY-140174
-
-
- HY-133272
-
-
- HY-140205
-
-
- HY-130195
-
-
- HY-140490
-
-
- HY-140034
-
-
- HY-141331
-
-
- HY-140515
-
-
- HY-141107
-
-
- HY-42774
-
Ms-PEG4-Ms
1,11-Bis(methanesulfonyloxy)-3,6,9-trioxandecane
|
PROTAC Linkers
|
Cancer
|
Ms-PEG4-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-132051
-
-
- HY-138433
-
-
- HY-133350
-
-
- HY-132105
-
-
- HY-140448
-
-
- HY-132059
-
-
- HY-133454
-
-
- HY-132029
-
-
- HY-141294
-
-
- HY-133467
-
-
- HY-133396
-
-
- HY-138479
-
-
- HY-140371
-
-
- HY-141097
-
-
- HY-138336
-
-
- HY-W096156
-
-
- HY-140966
-
-
- HY-140969
-
-
- HY-138368
-
-
- HY-132028
-
-
- HY-140196
-
-
- HY-132074
-
-
- HY-141307
-
-
- HY-130900
-
-
- HY-138720
-
-
- HY-130597
-
-
- HY-138733
-
-
- HY-140229
-
-
- HY-W096146
-
-
- HY-138459
-
-
- HY-134707
-
-
- HY-140404
-
-
- HY-138335
-
-
- HY-138759
-
-
- HY-140805
-
-
- HY-140814
-
-
- HY-140209
-
-
- HY-133210
-
-
- HY-140974
-
-
- HY-140827
-
-
- HY-133478
-
-
- HY-132077
-
-
- HY-138420
-
-
- HY-138766
-
-
- HY-130907
-
-
- HY-130856
-
-
- HY-138434
-
-
- HY-140220
-
-
- HY-125534
-
-
- HY-141306
-
-
- HY-141205
-
-
- HY-133474
-
-
- HY-W096074
-
-
- HY-133497
-
-
- HY-130833
-
-
- HY-W096145
-
-
- HY-W096071
-
-
- HY-134747
-
-
- HY-140959
-
-
- HY-130832
-
-
- HY-130348
-
-
- HY-W004697
-
-
- HY-140066
-
-
- HY-W096164
-
-
- HY-W096107
-
-
- HY-140195
-
-
- HY-143832
-
-
- HY-130855
-
-
- HY-141207
-
-
- HY-133379
-
-
- HY-140363
-
-
- HY-133349
-
-
- HY-138340
-
-
- HY-140701
-
-
- HY-140936
-
-
- HY-134717
-
-
- HY-133455
-
-
- HY-140821
-
-
- HY-141098
-
-
- HY-140170
-
-
- HY-133000
-
-
- HY-138371
-
-
- HY-141261
-
-
- HY-140797
-
-
- HY-138374
-
-
- HY-141214
-
-
- HY-130496
-
-
- HY-141283
-
-
- HY-138419
-
-
- HY-133270
-
-
- HY-138427
-
-
- HY-133347
-
-
- HY-132090
-
-
- HY-118781
-
-
- HY-140154
-
-
- HY-141397
-
-
- HY-140986
-
-
- HY-140304
-
-
- HY-138329
-
-
- HY-130829
-
-
- HY-140781
-
-
- HY-114843
-
-
- HY-140894
-
-
- HY-130902
-
-
- HY-140279
-
-
- HY-140216
-
-
- HY-140891
-
-
- HY-138314
-
-
- HY-W096105
-
-
- HY-133508
-
-
- HY-138728
-
-
- HY-138404
-
-
- HY-133280
-
-
- HY-133293
-
-
- HY-133391
-
-
- HY-140762
-
-
- HY-133370
-
-
- HY-138516
-
-
- HY-138740
-
-
- HY-138315
-
-
- HY-140815
-
-
- HY-140198
-
-
- HY-132096
-
-
- HY-132024
-
-
- HY-141228
-
-
- HY-W190843
-
-
- HY-140726
-
-
- HY-133269
-
-
- HY-W190968
-
-
- HY-132020
-
-
- HY-133480
-
-
- HY-133369
-
-
- HY-140800
-
-
- HY-140901
-
-
- HY-140778
-
-
- HY-140062
-
-
- HY-133326
-
-
- HY-W190728
-
-
- HY-141327
-
-
- HY-133381
-
-
- HY-132107
-
-
- HY-140214
-
-
- HY-133315
-
-
- HY-138765
-
-
- HY-141102
-
-
- HY-133476
-
-
- HY-130580
-
-
- HY-140825
-
-
- HY-141105
-
-
- HY-140308
-
-
- HY-132011
-
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- HY-138460
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